When is evidence sufficient for decision-making? A framework for understanding the pace of evidence adoption.

abstract：:Aim: Breast cancer is a leading cause of cancer among women. Because guidelines on screening for breast cancer for certain ages are controversial, many experts advocate the use of shared decision making (SDM) using validated decision aids (DAs). Recent studies have concluded that DAs are beneficial; however, the resul...

journal_title：Journal of comparative effectiveness research

authors： Yu L,Li P,Yang S,Guo P,Zhang X,Liu N,Wang J,Zhang W

更新日期：2020-10-01 00:00:00

abstract：:The intense competition that accompanied the growth of internet-based companies ushered in the era of 'big data' characterized by major innovations in processing of very large amounts of data and the application of advanced analytics including data mining and machine learning. Healthcare is on the cusp of its own era ...

journal_title：Journal of comparative effectiveness research

authors： Berger ML,Doban V

更新日期：2014-03-01 00:00:00

abstract：AIM:Compare the safety and efficacy of intermittent fenofibrate versus simvastatin in chronic hemodialysis patients. PATIENTS & METHODS:Sixty patients received either fenofibrate 100 mg or simvastatin 20 mg after their dialysis session (parallel study). The safety and efficacy of drugs on lipid profile, oxidized low-d...

journal_title：Journal of comparative effectiveness research

authors： Abdel Magid AM,Abbassi MM,Iskander EEM,Mohamady O,Farid SF

更新日期：2017-07-01 00:00:00

abstract：:AIMS: Stakeholder engagement is fundamental to comparative effectiveness research (CER), but lacks consistent terminology. This paper aims to define stakeholder engagement and present a conceptual model for involving stakeholders in CER. MATERIALS #ENTITYSTARTX00026; METHODS: The definitions and model were developed f...

journal_title：Journal of comparative effectiveness research

authors： Deverka PA,Lavallee DC,Desai PJ,Esmail LC,Ramsey SD,Veenstra DL,Tunis SR

更新日期：2012-03-01 00:00:00

abstract：:Aim: Increasing use of selective serotonin-reuptake inhibitors (SSRIs) in Scotland, coupled with safety concerns with some SSRIs, and the increasing availability of generic SSRIs, have resulted in multiple initiatives to improve the quality and efficiency of their prescribing in Scotland. Our aim is to assess their in...

journal_title：Journal of comparative effectiveness research

authors： Godman B,Kurdi A,McCabe H,Johnson CF,Barbui C,MacBride-Stewart S,Hurding S,Leporowski A,Bennie M,Morton A

更新日期：2019-05-01 00:00:00

abstract：AIM:To evaluate treatment patterns among elderly, newly diagnosed stage IV breast cancer patients receiving HER-2-targeted therapy. METHODS:Women aged 65+ with an incident diagnosis of stage IV breast cancer (index) and no history of other cancer were identified from 2006 to 2010 linked Surveillance, Epidemiology and ...

journal_title：Journal of comparative effectiveness research

authors： Lang K,Hao Y,Huang H,Lin I,Rogerio JW,Menzin J

更新日期：2014-09-01 00:00:00

abstract：:The 11 big health data networks participating in the AcademyHealth Electronic Data Methods Forum represent cutting-edge efforts to harness the power of big health data for research and quality improvement. This paper is a comparative case study based on site visits conducted with a subset of these large infrastructure...

journal_title：Journal of comparative effectiveness research

authors： Holve E,Segal C

更新日期：2014-11-01 00:00:00

abstract：:Choice-based conjoint (CBC) is used to understand how individuals develop preferences for decision alternatives. When decision alternatives can be described in terms of attributes, researchers want to determine the value respondents attach to various attribute levels. Popular in psychology, marketing, economics and ot...

journal_title：Journal of comparative effectiveness research

authors： Chitturi P,Carides A

更新日期：2020-01-01 00:00:00

abstract：:Functional tricuspid regurgitation (FTR) is an acquired valvular abnormality that is most frequently encountered during the evaluation and operative management of left-sided heart failure and left heart valve disease. Observational studies have demonstrated that uncorrected significant FTR during mitral valve surgery ...

journal_title：Journal of comparative effectiveness research

authors： Rogers JH,Bolling SF

更新日期：2015-11-01 00:00:00

abstract：:Aim: To evaluate the patterns of cancer patients-assessed quality of outpatient care in the USA. Materials & methods: Medical Expenditure Panel Survey datasets for the years 2011, 2013, 2015 and 2017 were accessed and adult participants with a history of cancer diagnosis were reviewed. Participants' assessments of dif...

journal_title：Journal of comparative effectiveness research

authors： Abdel-Rahman O

更新日期：2020-09-01 00:00:00

abstract：:Aim: Indirect treatment comparisons are used when no direct comparison is available. Comparison networks should satisfy the transitivity assumption, that is, equal likelihood of treatment assignment for a given patient based on comparability of studies. Materials & methods: Seven criteria were evaluated across 18 rand...

journal_title：Journal of comparative effectiveness research

authors： Tremblay G,Westley T,Forsythe A,Pelletier C,Briggs A

更新日期：2019-11-01 00:00:00

abstract：:Concerted efforts are underway to improve healthcare decision-making through patient-centered outcomes research. These efforts are supported by the Patient-Centered Outcomes Research Trust Fund, which was established within the Patient Protection and Affordable Care Act. This article focuses on describing national dat...

journal_title：Journal of comparative effectiveness research

authors： Dymek C,Gingold J,Shanbhag A,Fridsma D,Yong PL

更新日期：2015-01-01 00:00:00

abstract：AIM:GNE myopathy, a rare, severe, progressive myopathy, presents with lower extremity distal muscle weakness. The GNE myopathy functional activity scale (GNEM-FAS) evaluates the impact of GNE myopathy on functioning in adults. This paper presents the psychometric validation of the GNEM-FAS. PATIENTS & METHODS:Validati...

journal_title：Journal of comparative effectiveness research

authors： Mayhew J,Bonner N,Arbuckle R,Turnbull A,Bowden A,Skrinar A

更新日期：2018-04-01 00:00:00

abstract：AIM:We conducted a meta-analysis to compare the efficacy and safety of oral and intravenous applications of tranexamic acid (TXA) in total hip arthroplasty (THA). MATERIALS & METHODS:Electronic databases, including PubMed, Cochrane CENTRAL, ScienceDirect and Embase, were searched to identify the studies comparing the ...

journal_title：Journal of comparative effectiveness research

authors： Wang L,Cao JG,Liu J

更新日期：2019-04-01 00:00:00

abstract：:Aim: Medicaid versus private primary insurance status may predict in-hospital mortality and morbidity after total knee arthroplasty (TKA). Materials & methods: Regression models were used to test our hypothesis in patients in the State Inpatient Database (SID) from five states who underwent primary TKA from January 20...

journal_title：Journal of comparative effectiveness research

authors： Maman SR,Andreae MH,Gaber-Baylis LK,Turnbull ZA,White RS

更新日期：2019-10-01 00:00:00

abstract：AIM:Laboratory test (lab) results may be useful to detect incident diabetes in electronic health record and claims-based studies. RESEARCH DESIGN & METHODS:Using the Mini-Sentinel distributed database, we assessed the value of lab results added to diagnosis codes and dispensing claims to identify incident diabetes. R...

journal_title：Journal of comparative effectiveness research

authors： Flory JH,Roy J,Gagne JJ,Haynes K,Herrinton L,Lu C,Patorno E,Shoaibi A,Raebel MA

更新日期：2017-01-01 00:00:00

abstract：:Comparative effectiveness research (CER) calls for substantial changes in the way clinical research is conducted, interpreted and practically applied in the USA, in order to produce useful clinical evidence. Departing from classic efficacy and effectiveness research, the evolving CER paradigm requires structural and s...

journal_title：Journal of comparative effectiveness research

authors： Greenfield S,Kaplan SH

更新日期：2012-05-01 00:00:00

abstract：AIMS:This study aimed to identify methods to engage hard-to-reach patients in the research process. MATERIALS & METHODS:With funding from the Patient-Centered Outcomes Research Institute (Washington, DC, USA), the University of Maryland (MD, USA) conducted 20 focus groups and one individual interview. The sample consi...

journal_title：Journal of comparative effectiveness research

authors： Kauffman KS,Dosreis S,Ross M,Barnet B,Onukwugha E,Mullins CD

更新日期：2013-05-01 00:00:00

abstract：:Rationale, aim & objective: The goal of this study was to examine the health and economic impacts related to increased utilization of the Duke Smoking Cessation Program resulting from the addition of two relatively new referral methods - Best Practice Advisory and Population Outreach. Materials & methods: In a compani...

journal_title：Journal of comparative effectiveness research

authors： Datta SK,Dennis PA,Davis JM

更新日期：2020-08-01 00:00:00

abstract：:Aim: We assessed reporting of data on sex/gender and race/ethnicity in randomized controlled trials of interventions published in the highest-ranking anesthesiology journals from 2014 to 2017. Methods: We extracted data regarding terminology for sex/gender, proportion of participants according to the race/gender and r...

journal_title：Journal of comparative effectiveness research

authors： Begic D,Janda-Martinac C,Vrdoljak M,Puljak L

更新日期：2019-12-01 00:00:00

abstract：:Aim: To compare secukinumab with infliximab in biologic-naive patients with psoriatic arthritis using matching-adjusted indirect comparison. Patients & methods: Individual patient baseline data for secukinumab were matched to published aggregate data for infliximab by key baseline characteristics, with matching weight...

journal_title：Journal of comparative effectiveness research

authors： Strand V,McInnes I,Mease P,Nash P,Thom H,Kalyvas C,Hunger M,Gandhi K,Pricop L,Jugl S,Choy E

更新日期：2019-05-01 00:00:00

abstract：:Aim: The systematic review assessed the effect of mindfulness-based interventions on the quality of life among women with breast cancer. Methods: PubMed, Cochrane library, EMBASE, Web of Science and CINAHL databases were searched for studies published. Our review assessed the effect of mindfulness-based interventions ...

journal_title：Journal of comparative effectiveness research

authors： Zhang X,Liu D,Li Y,Zhang Y,Zhang B,Wang X,Wang G

更新日期：2019-08-01 00:00:00

abstract：AIM:To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination and implementation (D&I) via NIH-funded Clinical and Translational Science Award (CTSA) institutions. MATERIALS & METHODS:Key informant interviews were conducted with 18...

journal_title：Journal of comparative effectiveness research

authors： Morrato EH,Concannon TW,Meissner P,Shah ND,Turner BJ

更新日期：2013-03-01 00:00:00

abstract：AIMS:The potential of dedicated Breast-CT is evaluated by simulating its impact onto the performance of the German breast cancer screening program. Attendance rates, cancer detection and economic implications are quantified. METHODS:Based on a prospective health technology assessment approach, we simulated screening i...

journal_title：Journal of comparative effectiveness research

authors： Ruile G,Djanatliev A,Kriza C,Meier F,Leb I,Kalender WA,Kolominsky-Rabas PL,National Leading-Edge Cluster Medical Technologies ‘Medical Valley EMN’.

更新日期：2015-11-01 00:00:00

abstract：:Since 2010, four oral anticoagulants have been approved for marketing in addition to warfarin for treatment of thromboembolic disease. Limited head-to-head data exist comparing these treatments, leaving patients and clinicians with little guidance for selecting a strategy that balances recurrence reduction with bleedi...

journal_title：Journal of comparative effectiveness research

authors： Krumme AA,Pawar A,Schneeweiss S,Glynn RJ,Choudhry NK,Kulldorff M,Ortiz AS,Avorn J,Gagne JJ

更新日期：2018-01-01 00:00:00

abstract：AIM:Details of data quality and how quality issues were solved have not been reported in published comparative effectiveness studies using electronic health record data. METHODS:We developed a conceptual framework of data quality assessment and preprocessing and apply it to a study comparing angiotensin-converting enz...

journal_title：Journal of comparative effectiveness research

authors： Huang Y,Voorham J,Haaijer-Ruskamp FM

更新日期：2016-07-01 00:00:00

abstract：AIM:To evaluate overall survival (OS) in unresectable American Joint Committee on Cancer (AJCC) stage I/II hepatocellular carcinoma (HCC) treated with drug-eluting-bead transarterial chemoembolization (DEB-TACE) versus best supportive care. MATERIALS & METHODS:OS in consecutive patients with AJCC stage I/II unresectab...

journal_title：Journal of comparative effectiveness research

authors： Xing M,Kokabi N,Prajapati HJ,Close O,Ludwig JM,Kim HS

更新日期：2016-03-01 00:00:00

abstract：:Clinical trial designs often fail to deliver data that jointly satisfy evolving demands of both regulatory and reimbursement authorities. We propose a new multi-tiered trial design to integrate efficacy and effectiveness, and address the evolving needs of authorities. The mixed randomized trial allocates patients firs...

journal_title：Journal of comparative effectiveness research

authors： Alsop J,Scott M,Archey W

更新日期：2016-11-01 00:00:00

abstract：AIM:Reducing the fluctuation of blood pressure has recently been recognized as a potential target for improving management of hypertension to prevent cardiovascular events, particularly for strokes. Some randomized controlled trials demonstrated that amlodipine can effectively reduce blood pressure as a well-establishe...

journal_title：Journal of comparative effectiveness research

authors： Zhang L,Yang J,Li L,Liu D,Xie X,Dong P,Lin Y

更新日期：2018-07-01 00:00:00

abstract：AIMS:To develop principles for planning and conducting comparative effectiveness research (CER). METHODS:Beginning with a modified existing list of health technology assessment principles, we developed a set of CER principles using literature review, engagement of multiple experts and broad stakeholder feedback. RESU...

journal_title：Journal of comparative effectiveness research

authors： Luce BR,Drummond MF,Dubois RW,Neumann PJ,Jönsson B,Siebert U,Schwartz JS

更新日期：2012-09-01 00:00:00