Abstract:
AIM:To estimate healthcare utilization and costs in amyloid light-chain (AL) amyloidosis. PATIENTS & METHODS:AL amyloidosis patients were identified in 2007-2015 claims databases if they had ≥1 inpatient/≥2 outpatient claims consistent with AL amyloidosis and received ≥1 AL-specific treatment. Descriptive statistics were reported. RESULTS:50.1% (n = 3670) were admitted ≥1 time during the year, 11.3% (n = 827) ≥3 times. From 2007 to 2015, bortezomib use increased from 4.6 to 25.3%; melphalan use decreased from 18.9 to 2.0%; costs increased from 92,866 to $114,030. Among incident patients with at least 2 years of follow-up, healthcare utilization and costs decreased from first to second year post-diagnosis. CONCLUSION:AL chemotherapy-based prescribing practices changed. Total annual healthcare costs increased over time among AL amyloidosis patients.
journal_name
J Comp Eff Resjournal_title
Journal of comparative effectiveness researchauthors
Quock TP,Yan T,Chang E,Guthrie S,Broder MSdoi
10.2217/cer-2017-0100subject
Has Abstractpub_date
2018-06-01 00:00:00pages
549-559issue
6eissn
2042-6305issn
2042-6313journal_volume
7pub_type
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