Experimental design issues in choice-based conjoint applied to patient choice in healthcare.

abstract：:Degenerative spine disorders are a significant cause of patient morbidity and are a prominent factor in healthcare costs in many countries. Pressure for healthcare cost control and the desire for improved outcomes have led to an expanding emphasis on evidence-based medicine methodologies in spine research. Determinati...

journal_title：Journal of comparative effectiveness research

authors： Lake WB,Brooks NP,Resnick DK

更新日期：2013-01-01 00:00:00

abstract：:There is increasing attention in the US healthcare system on the delivery of high-quality care, an issue central to oncology. In the report 'Crossing the Quality Chasm', the Institute of Medicine identified six aims for improving healthcare quality: safe, effective, patient-centered, timely, efficient and equitable. T...

journal_title：Journal of comparative effectiveness research

authors： Broughman JR,Chen RC

更新日期：2016-05-01 00:00:00

abstract：AIM:Details of data quality and how quality issues were solved have not been reported in published comparative effectiveness studies using electronic health record data. METHODS:We developed a conceptual framework of data quality assessment and preprocessing and apply it to a study comparing angiotensin-converting enz...

journal_title：Journal of comparative effectiveness research

authors： Huang Y,Voorham J,Haaijer-Ruskamp FM

更新日期：2016-07-01 00:00:00

abstract：AIM:The importance of adjusting for cross-study heterogeneity when conducting network meta-analyses (NMAs) was demonstrated using a case study of biologic therapies for moderate-to-severe plaque psoriasis. METHODS:Bayesian NMAs were conducted for Psoriasis Area and Severity Index 90 response. Several covariates were c...

journal_title：Journal of comparative effectiveness research

authors： Cameron C,Hutton B,Druchok C,McElligott S,Nair S,Schubert A,Situ A,Varu A,Villacorta R

更新日期：2018-11-01 00:00:00

abstract：AIM:Explore perspectives of adolescent and young adult (AYA) and parent stakeholders regarding their engagement in comparative effectiveness research (CER) evaluating cholesterol screening and treatment strategies for 17-21 year olds. METHODS:All nine AYAs and parent stakeholders participating in a 20-member panel of ...

journal_title：Journal of comparative effectiveness research

authors： Saunders T,Mackie TI,Shah S,Gooding H,de Ferranti SD,Leslie LK

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Palliative cancer patients often require clinic or hospital follow-up after any treatment intervention they may have received. This is typically done in person at either a hospital or a clinic. In these advanced cancer patients, this may be burdensome and result in attrition. Telephone follow-up is becoming ...

journal_title：Journal of comparative effectiveness research

authors： Zhou M,Holden L,Bedard G,Zeng L,Lam H,Chu D,Lao N,Lauzon N,Chow E

更新日期：2012-11-01 00:00:00

abstract：AIM:GNE myopathy, a rare, severe, progressive myopathy, presents with lower extremity distal muscle weakness. The GNE myopathy functional activity scale (GNEM-FAS) evaluates the impact of GNE myopathy on functioning in adults. This paper presents the psychometric validation of the GNEM-FAS. PATIENTS & METHODS:Validati...

journal_title：Journal of comparative effectiveness research

authors： Mayhew J,Bonner N,Arbuckle R,Turnbull A,Bowden A,Skrinar A

更新日期：2018-04-01 00:00:00

abstract：AIM:To provide an overview of thresholds for incremental cost-effectiveness ratios (ICERs) representing willingness-to-pay (WTP) across multiple countries and insights into exemptions pertaining to the ICER (e.g., cancer). To compare ICER thresholds to individual country's estimated ability-to-pay. MATERIALS & METHODS...

journal_title：Journal of comparative effectiveness research

authors： Schwarzer R,Rochau U,Saverno K,Jahn B,Bornschein B,Muehlberger N,Flatscher-Thoeni M,Schnell-Inderst P,Sroczynski G,Lackner M,Schall I,Hebborn A,Pugner K,Fehervary A,Brixner D,Siebert U

更新日期：2015-09-01 00:00:00

abstract：:Evaluation of: Olanow CW, Kieburtz K, Odin P et al. Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study. Lancet Neurol. 13(2), 141-149 (2014). Levodopa-induced motor complications, including mot...

journal_title：Journal of comparative effectiveness research

authors： Guthikonda LN,Lyons KE,Pahwa R

更新日期：2014-07-01 00:00:00

abstract：:Functional tricuspid regurgitation (FTR) is an acquired valvular abnormality that is most frequently encountered during the evaluation and operative management of left-sided heart failure and left heart valve disease. Observational studies have demonstrated that uncorrected significant FTR during mitral valve surgery ...

journal_title：Journal of comparative effectiveness research

authors： Rogers JH,Bolling SF

更新日期：2015-11-01 00:00:00

abstract：:Patients with acute coronary syndromes and severe multivessel or left main coronary artery disease have better outcomes when prompt revascularization is performed in addition to optimal medical therapy (OMT). However, in patients with stable ischemic heart disease, randomized strategy trials have revealed equipoise be...

journal_title：Journal of comparative effectiveness research

authors： Torosoff MT,Sidhu MS,Desai KP,Fein SA,Boden WE

更新日期：2015-09-01 00:00:00

abstract：AIM:Current stroke severity scales cannot be used for archival data. We develop and validate a measure of stroke severity at hospital discharge (Stroke Administrative Severity Index [SASI]) for use in billing data. METHODS:We used the NIH Stroke Scale (NIHSS) as the theoretical framework and identified 285 relevant In...

journal_title：Journal of comparative effectiveness research

authors： Simpson AN,Wilmskoetter J,Hong I,Li CY,Jauch EC,Bonilha HS,Anderson K,Harvey J,Simpson KN

更新日期：2018-04-01 00:00:00

abstract：:Aim: Breast cancer is a leading cause of cancer among women. Because guidelines on screening for breast cancer for certain ages are controversial, many experts advocate the use of shared decision making (SDM) using validated decision aids (DAs). Recent studies have concluded that DAs are beneficial; however, the resul...

journal_title：Journal of comparative effectiveness research

authors： Yu L,Li P,Yang S,Guo P,Zhang X,Liu N,Wang J,Zhang W

更新日期：2020-10-01 00:00:00

abstract：:Aim: To perform cost-effectiveness analysis (CEA) and budget impact analysis (BIA) comparing stenting to standard medical treatment (SMT) for the management of deep venous outflow obstruction and leg ulcers from the Italian Healthcare Service perspective. Materials & methods: A Markov model was developed to project co...

journal_title：Journal of comparative effectiveness research

authors： Rognoni C,Lugli M,Maleti O,Tarricone R

更新日期：2020-07-01 00:00:00

abstract：AIM:To evaluate treatment patterns among elderly, newly diagnosed stage IV breast cancer patients receiving HER-2-targeted therapy. METHODS:Women aged 65+ with an incident diagnosis of stage IV breast cancer (index) and no history of other cancer were identified from 2006 to 2010 linked Surveillance, Epidemiology and ...

journal_title：Journal of comparative effectiveness research

authors： Lang K,Hao Y,Huang H,Lin I,Rogerio JW,Menzin J

更新日期：2014-09-01 00:00:00

abstract：:Aim: Dedicated brain imaging is advocated by the National Comprehensive Cancer Network guidelines for newly diagnosed non-small-cell cancer (NSCLC) patients beyond stage I. The current study assessed the performance characteristics of this recommendation. Methods: Through accessing the Surveillance, Epidemiology and E...

journal_title：Journal of comparative effectiveness research

authors： Abdel-Rahman O

更新日期：2019-06-01 00:00:00

abstract：AIM:To evaluate overall survival (OS) in unresectable American Joint Committee on Cancer (AJCC) stage I/II hepatocellular carcinoma (HCC) treated with drug-eluting-bead transarterial chemoembolization (DEB-TACE) versus best supportive care. MATERIALS & METHODS:OS in consecutive patients with AJCC stage I/II unresectab...

journal_title：Journal of comparative effectiveness research

authors： Xing M,Kokabi N,Prajapati HJ,Close O,Ludwig JM,Kim HS

更新日期：2016-03-01 00:00:00

abstract：AIM:Laboratory test (lab) results may be useful to detect incident diabetes in electronic health record and claims-based studies. RESEARCH DESIGN & METHODS:Using the Mini-Sentinel distributed database, we assessed the value of lab results added to diagnosis codes and dispensing claims to identify incident diabetes. R...

journal_title：Journal of comparative effectiveness research

authors： Flory JH,Roy J,Gagne JJ,Haynes K,Herrinton L,Lu C,Patorno E,Shoaibi A,Raebel MA

更新日期：2017-01-01 00:00:00

abstract：AIM:To measure the private and social benefits of donor insemination (DI). METHODS:An empirical model investigates the general public and DI clients' willingness to pay (WTP) for DI, and the willingness of potential donors to become altruistic or paid sperm donors. RESULTS:The general public and DI clients value DI a...

journal_title：Journal of comparative effectiveness research

authors： Gonen LD

更新日期：2017-03-01 00:00:00

abstract：:Aim: To compare efficacy between total gastrectomy (TG) and proximal gastrectomy (PG) for upper-third gastric cancer. Materials & methods: PubMed, Embase and Cochrane library were searched to select suitable researches. Stata was used for meta-analysis including 5-year overall survival rate, recurrence rate, complicat...

journal_title：Journal of comparative effectiveness research

authors： Chen YC,Lu L,Fan KH,Wang DH,Fu WH

更新日期：2019-07-01 00:00:00

abstract：:Concerted efforts are underway to improve healthcare decision-making through patient-centered outcomes research. These efforts are supported by the Patient-Centered Outcomes Research Trust Fund, which was established within the Patient Protection and Affordable Care Act. This article focuses on describing national dat...

journal_title：Journal of comparative effectiveness research

authors： Dymek C,Gingold J,Shanbhag A,Fridsma D,Yong PL

更新日期：2015-01-01 00:00:00

abstract：:Comparative effectiveness research (CER) calls for substantial changes in the way clinical research is conducted, interpreted and practically applied in the USA, in order to produce useful clinical evidence. Departing from classic efficacy and effectiveness research, the evolving CER paradigm requires structural and s...

journal_title：Journal of comparative effectiveness research

authors： Greenfield S,Kaplan SH

更新日期：2012-05-01 00:00:00

abstract：:AIMS: Stakeholder engagement is fundamental to comparative effectiveness research (CER), but lacks consistent terminology. This paper aims to define stakeholder engagement and present a conceptual model for involving stakeholders in CER. MATERIALS #ENTITYSTARTX00026; METHODS: The definitions and model were developed f...

journal_title：Journal of comparative effectiveness research

authors： Deverka PA,Lavallee DC,Desai PJ,Esmail LC,Ramsey SD,Veenstra DL,Tunis SR

更新日期：2012-03-01 00:00:00

abstract：:Rationale, aim & objective: The goal of this study was to examine the health and economic impacts related to increased utilization of the Duke Smoking Cessation Program resulting from the addition of two relatively new referral methods - Best Practice Advisory and Population Outreach. Materials & methods: In a compani...

journal_title：Journal of comparative effectiveness research

authors： Datta SK,Dennis PA,Davis JM

更新日期：2020-08-01 00:00:00

abstract：AIM:Studies on multiple sclerosis in Saudi Arabia remain scant, particularly studies on the psychological aspects. This study measures severities of depression, anxiety and stress, and compares them to the used disease-modifying treatment. MATERIALS & METHODS:Cross-sectional study using a phone questionnaire targeting...

journal_title：Journal of comparative effectiveness research

authors： Al-Hussain F,Al-Salloum N,Alazwary N,Saeedi J,Howaidi S,Daif A

更新日期：2017-07-01 00:00:00

abstract：:Clinical trial designs often fail to deliver data that jointly satisfy evolving demands of both regulatory and reimbursement authorities. We propose a new multi-tiered trial design to integrate efficacy and effectiveness, and address the evolving needs of authorities. The mixed randomized trial allocates patients firs...

journal_title：Journal of comparative effectiveness research

authors： Alsop J,Scott M,Archey W

更新日期：2016-11-01 00:00:00

abstract：:Aim: To evaluate the patterns of cancer patients-assessed quality of outpatient care in the USA. Materials & methods: Medical Expenditure Panel Survey datasets for the years 2011, 2013, 2015 and 2017 were accessed and adult participants with a history of cancer diagnosis were reviewed. Participants' assessments of dif...

journal_title：Journal of comparative effectiveness research

authors： Abdel-Rahman O

更新日期：2020-09-01 00:00:00

abstract：AIM:To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination and implementation (D&I) via NIH-funded Clinical and Translational Science Award (CTSA) institutions. MATERIALS & METHODS:Key informant interviews were conducted with 18...

journal_title：Journal of comparative effectiveness research

authors： Morrato EH,Concannon TW,Meissner P,Shah ND,Turner BJ

更新日期：2013-03-01 00:00:00

abstract：:Aim: To compare secukinumab with infliximab in biologic-naive patients with psoriatic arthritis using matching-adjusted indirect comparison. Patients & methods: Individual patient baseline data for secukinumab were matched to published aggregate data for infliximab by key baseline characteristics, with matching weight...

journal_title：Journal of comparative effectiveness research

authors： Strand V,McInnes I,Mease P,Nash P,Thom H,Kalyvas C,Hunger M,Gandhi K,Pricop L,Jugl S,Choy E

更新日期：2019-05-01 00:00:00

abstract：:Alternative approaches to the current rebate system are being considered by policymakers and stakeholders in the private insurance market. This paper presents an analysis of three alternative options to the current rebate model: retaining retroactive rebates but requiring 100% pass-through of rebates and fees to plan ...

journal_title：Journal of comparative effectiveness research

authors： Pearson SD,Segel C,Cole A,Henshall C,Towse A

更新日期：2019-10-01 00:00:00