Perfect proton selectivity in ion transport through two-dimensional crystals.

abstract：:Removal of internal transcribed spacer 2 (ITS2) from pre-ribosomal RNA is essential to make functional ribosomes. This complicated processing reaction begins with a single endonucleolytic cleavage followed by exonucleolytic trimming at both new cleavage sites to generate mature 5.8S and 25S rRNA. We reconstituted the ...

journal_title：Nature communications

authors： Fromm L,Falk S,Flemming D,Schuller JM,Thoms M,Conti E,Hurt E

更新日期：2017-11-27 00:00:00

abstract：:Inspired by mammalian skins, soft hybrids integrating the merits of elastomers and hydrogels have potential applications in diverse areas including stretchable and bio-integrated electronics, microfluidics, tissue engineering, soft robotics and biomedical devices. However, existing hydrogel-elastomer hybrids have limi...

journal_title：Nature communications

authors： Yuk H,Zhang T,Parada GA,Liu X,Zhao X

更新日期：2016-06-27 00:00:00

abstract：:Understanding the response of granular matter to intrusion of solid objects is key to modelling many aspects of behaviour of granular matter, including plastic flow. Here we report a general model for such a quasistatic process. Using a range of experiments, we first show that the relation between the penetration dept...

journal_title：Nature communications

authors： Kang W,Feng Y,Liu C,Blumenfeld R

更新日期：2018-03-16 00:00:00

abstract：:The design and assembly of artificial protocell consortia displaying dynamical behaviours and systems-based properties are emerging challenges in bottom-up synthetic biology. Cellular processes such as morphogenesis and differentiation rely in part on reaction-diffusion gradients, and the ability to mimic rudimentary ...

journal_title：Nature communications

authors： Tian L,Li M,Patil AJ,Drinkwater BW,Mann S

更新日期：2019-07-25 00:00:00

abstract：:Nanostructured metasurfaces offer unique capabilities for subwavelength control of optical waves. Based on this potential, a large number of metasurfaces have been proposed recently as alternatives to standard optical elements. In most cases, however, these elements suffer from large chromatic aberrations, thus limiti...

journal_title：Nature communications

authors： Avayu O,Almeida E,Prior Y,Ellenbogen T

更新日期：2017-04-05 00:00:00

abstract：:Charge acceleration during an intense light field application to solids attracts much attention as elementary processes in high-harmonic generation and photoelectron emission. For manipulating such attosecond dynamics of charge, carrier-envelope-phase (CEP: relative phase between carrier oscillation of light field and...

journal_title：Nature communications

authors： Kawakami Y,Amano T,Ohashi H,Itoh H,Nakamura Y,Kishida H,Sasaki T,Kawaguchi G,Yamamoto HM,Yamamoto K,Ishihara S,Yonemitsu K,Iwai S

更新日期：2020-08-18 00:00:00

abstract：:It is a relatively new insight of classical statistics that empirical data can contain information about causation rather than mere correlation. First algorithms have been proposed that are capable of testing whether a presumed causal relationship is compatible with an observed distribution. However, no systematic met...

journal_title：Nature communications

authors： Chaves R,Majenz C,Gross D

更新日期：2015-01-06 00:00:00

abstract：:Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on the regulation of mTORC1, a critical kinase that regulates cell growth and proliferation. We report that suppleme...

journal_title：Nature communications

authors： Tan HWS,Sim AYL,Long YC

更新日期：2017-08-24 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder due to selective loss of motor neurons (MNs). Mutations in the fused in sarcoma (FUS) gene can cause both juvenile and late onset ALS. We generated and characterized induced pluripotent stem cells (iPSCs) from ALS patients with dif...

journal_title：Nature communications

authors： Guo W,Naujock M,Fumagalli L,Vandoorne T,Baatsen P,Boon R,Ordovás L,Patel A,Welters M,Vanwelden T,Geens N,Tricot T,Benoy V,Steyaert J,Lefebvre-Omar C,Boesmans W,Jarpe M,Sterneckert J,Wegner F,Petri S,Bohl D,Vande

更新日期：2017-10-11 00:00:00

abstract：:Chiral magnets are an emerging class of topological matter harboring localized and topologically protected vortex-like magnetic textures called skyrmions, which are currently under intense scrutiny as an entity for information storage and processing. Here, on the level of micromagnetics we rigorously show that chiral ...

journal_title：Nature communications

authors： Hoffmann M,Zimmermann B,Müller GP,Schürhoff D,Kiselev NS,Melcher C,Blügel S

更新日期：2017-08-21 00:00:00

abstract：:Compared with noble metals, semiconductors with surface plasmon resonance effect are another type of SERS substrate materials. The main obstacles so far are that the semiconducting materials are often unstable and easy to be further oxidized or decomposed by laser irradiating or contacting with corrosive substances. H...

journal_title：Nature communications

authors： Zhang Q,Li X,Ma Q,Zhang Q,Bai H,Yi W,Liu J,Han J,Xi G

更新日期：2017-04-24 00:00:00

abstract：:The downstream consequences of inflammation in the adult mammalian heart are formation of a non-functional scar, pathological remodelling and heart failure. In zebrafish, hydrogen peroxide released from a wound is the initial instructive chemotactic cue for the infiltration of inflammatory cells, however, the identity...

journal_title：Nature communications

authors： Evans MA,Smart N,Dubé KN,Bollini S,Clark JE,Evans HG,Taams LS,Richardson R,Lévesque M,Martin P,Mills K,Riegler J,Price AN,Lythgoe MF,Riley PR

更新日期：2013-01-01 00:00:00

abstract：:Electrochemical water splitting requires efficient water oxidation catalysts to accelerate the sluggish kinetics of water oxidation reaction. Here, we report a promisingly dendritic core-shell nickel-iron-copper metal/metal oxide electrode, prepared via dealloying with an electrodeposited nickel-iron-copper alloy as a...

journal_title：Nature communications

authors： Zhang P,Li L,Nordlund D,Chen H,Fan L,Zhang B,Sheng X,Daniel Q,Sun L

更新日期：2018-01-26 00:00:00

abstract：:Recent studies suggest a role for T lymphocytes in hypertension. However, whether T cells contribute to renal sodium retention and salt-sensitive hypertension is unknown. Here we demonstrate that T cells infiltrate into the kidney of salt-sensitive hypertensive animals. In particular, CD8+ T cells directly contact the...

journal_title：Nature communications

authors： Liu Y,Rafferty TM,Rhee SW,Webber JS,Song L,Ko B,Hoover RS,He B,Mu S

更新日期：2017-01-09 00:00:00

abstract：:Stimulation of TNFR1 by TNFα can promote three distinct alternative mechanisms of cell death: necroptosis, RIPK1-independent and -dependent apoptosis. How cells decide which way to die is unclear. Here, we report that TNFα-induced phosphorylation of RIPK1 in the intermediate domain by TAK1 plays a key role in regulati...

journal_title：Nature communications

authors： Geng J,Ito Y,Shi L,Amin P,Chu J,Ouchida AT,Mookhtiar AK,Zhao H,Xu D,Shan B,Najafov A,Gao G,Akira S,Yuan J

更新日期：2017-08-25 00:00:00

abstract：:Of the many challenges in building a wireless network at terahertz frequencies, link discovery remains one of the most critical and least explored. In a network of mobile receivers using narrow directional beams, how do the nodes rapidly locate each other? This direction information is crucial for beam forming and ste...

journal_title：Nature communications

authors： Ghasempour Y,Shrestha R,Charous A,Knightly E,Mittleman DM

更新日期：2020-04-24 00:00:00

abstract：:Large-scale genetic and genomic data are increasingly available and the major bottleneck in their analysis is a lack of sufficiently scalable computational tools. To address this problem in the context of complex traits analysis, we present DISSECT. DISSECT is a new and freely available software that is able to exploi...

journal_title：Nature communications

authors： Canela-Xandri O,Law A,Gray A,Woolliams JA,Tenesa A

更新日期：2015-12-11 00:00:00

abstract：:Inspired by biological neural systems, neuromorphic devices may open up new computing paradigms to explore cognition, learning and limits of parallel computation. Here we report the demonstration of a synaptic transistor with SmNiO₃, a correlated electron system with insulator-metal transition temperature at 130°C in ...

journal_title：Nature communications

authors： Shi J,Ha SD,Zhou Y,Schoofs F,Ramanathan S

更新日期：2013-01-01 00:00:00

abstract：:Extremely metal-poor galaxies with metallicity below 10% of the solar value in the local universe are the best analogues to investigating the interstellar medium at a quasi-primitive environment in the early universe. In spite of the ongoing formation of stars in these galaxies, the presence of molecular gas (which is...

journal_title：Nature communications

authors： Shi Y,Wang J,Zhang ZY,Gao Y,Hao CN,Xia XY,Gu Q

更新日期：2016-12-09 00:00:00

abstract：:In order to control and eradicate epidemic cholera, we need to understand how epidemics begin, how they spread, and how they decline and eventually end. This requires extensive sampling of epidemic disease over time, alongside the background of endemic disease that may exist concurrently with the epidemic. The unique ...

journal_title：Nature communications

authors： Dorman MJ,Domman D,Poklepovich T,Tolley C,Zolezzi G,Kane L,Viñas MR,Panagópulo M,Moroni M,Binsztein N,Caffer MI,Clare S,Dougan G,Salmond GPC,Parkhill J,Campos J,Thomson NR

更新日期：2020-10-01 00:00:00

abstract：:The sudden deterioration of patients with novel coronavirus disease 2019 (COVID-19) into critical illness is of major concern. It is imperative to identify these patients early. We show that a deep learning-based survival model can predict the risk of COVID-19 patients developing critical illness based on clinical cha...

journal_title：Nature communications

authors： Liang W,Yao J,Chen A,Lv Q,Zanin M,Liu J,Wong S,Li Y,Lu J,Liang H,Chen G,Guo H,Guo J,Zhou R,Ou L,Zhou N,Chen H,Yang F,Han X,Huan W,Tang W,Guan W,Chen Z,Zhao Y,Sang L,Xu Y,Wang W,Li S,Lu L,Zhang N

更新日期：2020-07-15 00:00:00

abstract：:Histone acetylation is known to affect the speed of seed germination, but the molecular regulatory basis of this remains ambiguous. Here we report that loss of function of two histone deacetylase-binding factors, SWI-INDEPENDENT3 (SIN3)-LIKE1 (SNL1) and SNL2, results in accelerated radicle protrusion and growth during...

journal_title：Nature communications

authors： Wang Z,Chen F,Li X,Cao H,Ding M,Zhang C,Zuo J,Xu C,Xu J,Deng X,Xiang Y,Soppe WJ,Liu Y

更新日期：2016-11-11 00:00:00

abstract：:Fluctuations in glacier motion are very common and are thought to be controlled by subglacial hydrology and till deformation. There are few instrumented studies that have monitored seasonal changes. We use the innovative Glacsweb subglacial in situ wireless probes, combined with dGPS and custom geophone data from an I...

journal_title：Nature communications

authors： Hart JK,Martinez K,Basford PJ,Clayton AI,Robson BA,Young DS

更新日期：2019-04-08 00:00:00

abstract：:Macrophage-mediated inflammation is thought to have a causal role in osteoarthritis-related pain and severity, and has been suggested to be triggered by endotoxins produced by the gastrointestinal microbiome. Here we investigate the relationship between joint pain and the gastrointestinal microbiome composition, and o...

journal_title：Nature communications

authors： Boer CG,Radjabzadeh D,Medina-Gomez C,Garmaeva S,Schiphof D,Arp P,Koet T,Kurilshikov A,Fu J,Ikram MA,Bierma-Zeinstra S,Uitterlinden AG,Kraaij R,Zhernakova A,van Meurs JBJ

更新日期：2019-10-25 00:00:00

abstract：:Maternal glucose levels during pregnancy impact the developing fetus, affecting metabolic health both early and later on in life. Both genetic and environmental factors influence maternal metabolism, but little is known about the genetic mechanisms that alter glucose metabolism during pregnancy. Here, we report that h...

journal_title：Nature communications

authors： Guo C,Ludvik AE,Arlotto ME,Hayes MG,Armstrong LL,Scholtens DM,Brown CD,Newgard CB,Becker TC,Layden BT,Lowe WL,Reddy TE

更新日期：2015-02-04 00:00:00

abstract：:The space charge layer (SCL) is generally considered one of the origins of the sluggish interfacial lithium-ion transport in all-solid-state lithium-ion batteries (ASSLIBs). However, in-situ visualization of the SCL effect on the interfacial lithium-ion transport in sulfide-based ASSLIBs is still a great challenge. He...

journal_title：Nature communications

authors： Wang L,Xie R,Chen B,Yu X,Ma J,Li C,Hu Z,Sun X,Xu C,Dong S,Chan TS,Luo J,Cui G,Chen L

更新日期：2020-11-18 00:00:00

abstract：:Biodiversity changes are lagging behind current climate warming. The underlying determinants of this climatic debt are unknown and yet critical to understand the impacts of climate change on the present biota and improve forecasts of biodiversity changes. Here we assess determinants of climatic debt accumulated in Fre...

journal_title：Nature communications

authors： Bertrand R,Riofrío-Dillon G,Lenoir J,Drapier J,de Ruffray P,Gégout JC,Loreau M

更新日期：2016-08-26 00:00:00

abstract：:Cotton is an important natural fiber crop, however, its comprehensive and high-resolution gene map is lacking. Here we integrate four complementary high-throughput techniques, including Pacbio long read Iso-seq, strand-specific RNA-seq, CAGE-seq, and PolyA-seq, to systematically explore the transcription landscape acr...

journal_title：Nature communications

authors： Wang K,Wang D,Zheng X,Qin A,Zhou J,Guo B,Chen Y,Wen X,Ye W,Zhou Y,Zhu Y

更新日期：2019-10-17 00:00:00

abstract：:Van Allen radiation belts are typically two zones of energetic particles encircling the Earth separated by the slot region. How the outer radiation belt electrons are accelerated to relativistic energies remains an unanswered question. Recent studies have presented compelling evidence for the local acceleration by ver...

journal_title：Nature communications

authors： Su Z,Zhu H,Xiao F,Zong QG,Zhou XZ,Zheng H,Wang Y,Wang S,Hao YX,Gao Z,He Z,Baker DN,Spence HE,Reeves GD,Blake JB,Wygant JR

更新日期：2015-12-22 00:00:00

abstract：:The nutritional environment to which animals are exposed in early life can lead to epigenetic changes in the genome that influence the risk of obesity in later life. Here, we demonstrate that the fibroblast growth factor-21 gene (Fgf21) is subject to peroxisome proliferator-activated receptor (PPAR) α-dependent DNA de...

journal_title：Nature communications

authors： Yuan X,Tsujimoto K,Hashimoto K,Kawahori K,Hanzawa N,Hamaguchi M,Seki T,Nawa M,Ehara T,Kitamura Y,Hatada I,Konishi M,Itoh N,Nakagawa Y,Shimano H,Takai-Igarashi T,Kamei Y,Ogawa Y

更新日期：2018-02-12 00:00:00