Hypertension in Premenopausal and Postmenopausal Women.

abstract：:Progressive abnormalities of passive stiffness or active relaxation of the myocardium that impair ventricular filling during diastole may be an important contributor to the development of heart failure in patients with preserved ejection fraction. In this review, we discuss the epidemiology and pathophysiology of dias...

journal_title：Current hypertension reports

authors： Janardhanan R,Desai AS,Solomon SD

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Review the renal nerve anatomy and physiology basics and explore the concept of global vs. selective renal denervation (RDN) to uncover some of the fundamental limitations of non-targeted renal nerve ablation and the potential superiority of selective RDN. RECENT FINDINGS:Recent trials testing the ef...

journal_title：Current hypertension reports

authors： Fudim M,Sobotka AA,Yin YH,Wang JW,Levin H,Esler M,Wang J,Sobotka PA

更新日期：2018-05-01 00:00:00

abstract：:LCZ696 is a single molecule which combines the angiotensin receptor blocker valsartan with the neprilysn inhibitor sacubitril (AHU377). In the recently published PARADIGM-HF trial, LCZ696 proved superior to enalapril in reducing overall mortality, heart failure hospitalizations, and other endpoints in patients with sy...

journal_title：Current hypertension reports

authors： Gradman AH

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review is intended to briefly describe the primary mechanistic pathways by which several common drugs can increase blood pressure. We also propose potential management strategies based on the underlying mechanisms responsible for the blood pressure elevation. RECENT FINDINGS:As hypertension is a...

journal_title：Current hypertension reports

authors： Lovell AR,Ernst ME

更新日期：2017-05-01 00:00:00

abstract：:Hypertension is a major cause of morbidity and mortality worldwide. Despite a myriad of oral agents, many patients fail to reach their target blood pressure. Electrical stimulation of the carotid sinus, an old therapeutic concept, lowers blood pressure by initiating the baroreflex and reducing sympathetic tone. Recent...

journal_title：Current hypertension reports

authors： Filippone JD,Sloand JA,Illig KA,Bisognano JD

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The intrarenal renin-angiotensin-aldosterone system (RAS) is an independent paracrine hormonal system with an increasingly prominent role in hypertension and renal disease. Two enzyme components of this system are angiotensin-converting enzyme (ACE) and more recently discovered ACE2. The purpose of th...

journal_title：Current hypertension reports

authors： Culver S,Li C,Siragy HM

更新日期：2017-09-19 00:00:00

abstract：PURPOSE OF REVIEW:This meta-analysis and systematic review was conducted to evaluate the effect of probiotics on blood pressure, body mass index (BMI), and blood glucose changes in patients with hypertension. RECENT FINDINGS:We searched the PubMed, Cochrane, Embase, and ProQuest databases using a combination of MeSH a...

journal_title：Current hypertension reports

authors： Chi C,Li C,Wu D,Buys N,Wang W,Fan H,Sun J

更新日期：2020-03-21 00:00:00

abstract：:Circulating angiotensin II (Ang II) combined with high salt intake increases sympathetic nerve activity (SNA) in some forms of hypertension. Ang II-induced increases in SNA are modest, delayed, and specific to certain vascular beds. The brain targets for circulating Ang II are neurons in the area postrema (AP), subfor...

journal_title：Current hypertension reports

authors： Osborn JW,Fink GD,Sved AF,Toney GM,Raizada MK

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Do dietary fats lower blood pressure? This review covers total fats, individual fatty acids and foods that provide specific fats. RECENT FINDINGS:Evidence for blood pressure lowering is stronger for supplements providing individual marine fatty acids than for fish intake since data on fish consumptio...

journal_title：Current hypertension reports

authors： Nestel PJ

更新日期：2019-02-12 00:00:00

abstract：:Hypertension (especially systolic hypertension) is very common in older persons. Systolic hypertension occurs because large conduit arteries become stiffer with age. Strong evidence from randomized trials suggests that treating systolic blood pressures initially higher than 160 mm Hg is extremely beneficial, and a rec...

journal_title：Current hypertension reports

authors： Hyman DJ,Taffet GE

更新日期：2009-10-01 00:00:00

abstract：:Primary aldosteronism (PA) is a common cause of arterial hypertension: in the PA Prevalence in Hypertensives (PAPY) Study, the prevalence of PA was 11.2% in consecutive referred hypertensive patients. When adrenal vein sampling (AVS) is available, two thirds of the cases can be attributed to a tumor and one third of c...

journal_title：Current hypertension reports

authors： Rossi GP

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review latest reports of the food products which might increase blood pressure and therefore might participate in the pathogenesis of hypertension. RECENT FINDINGS:Results of clinical study suggest that consumption of high-sodium food leads to transient increase in plasma sodium concentration. Thi...

journal_title：Current hypertension reports

authors： Adamczak M,Wiecek A

更新日期：2020-01-08 00:00:00

abstract：:Resistant hypertension is defined as blood pressure that remains uncontrolled despite using at least three antihypertensive medications in effective doses, ideally including a diuretic. Stricter blood pressure goals, higher obesity rates, older age, and increased use of certain exogenous substances are related to an i...

journal_title：Current hypertension reports

authors： Pimenta E,Calhoun DA

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Renal sympathetic denervation (RDN) as treatment option for hypertension has a strong rationale; however, variable effects on blood pressure (BP) have been reported ranging from non-response to marked reductions in BP. The absence of a procedural end point for RDN is one of the potential factors assoc...

journal_title：Current hypertension reports

authors： Hoogerwaard AF,de Jong MR,Elvan A

更新日期：2018-03-19 00:00:00

abstract：:We are used to thinking of angiotensin (Ang) II as a regulatory hormone that stimulates constriction of vascular smooth muscle cells, aldosterone release from the adrenal gland, and sodium reabsorption in the renal tubule. We have also become accustomed to understanding that Ang II may be formed and may act locally as...

journal_title：Current hypertension reports

authors： Luft FC

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the most recent literature on current strategies for the treatment of hypertension associated with pediatric obesity. RECENT FINDINGS:Over the last three decades, childhood and adolescent overweight and obesity prevalence in the USA has continued to rise. Unsurprisingly but rather disturbin...

journal_title：Current hypertension reports

authors： Binka E,Brady TM

更新日期：2019-02-12 00:00:00

abstract：:Young and middle-aged adults (ages ≤50 years) are increasingly prone to stroke, kidney disease, and worsening cardiovascular disease (CVD) mortality. An alarming increase in the prevalence of high blood pressure (BP) may underlie the adverse trend. However, there is often uncertainty in BP management for young and mid...

journal_title：Current hypertension reports

authors： Yano Y,Lloyd-Jones DM

更新日期：2016-11-01 00:00:00

abstract：:When a large multicenter research trial is abruptly terminated, it is usually a consequence of significant adverse events. In contrast, when the Randomized Aldactone Evaluation Study (RALES) mortality trial was discontinued 18 months early, it was because of the prominent salutary effect of spironolactone, added to st...

journal_title：Current hypertension reports

authors： Soberman JE,Weber KT

更新日期：2000-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide insight into the mechanisms underlying cerebral pathophysiology and to highlight possible methods for evaluation, screening, and surveillance of cerebral complications in preeclampsia. RECENT FINDINGS:The pathophysiology of eclampsia remains enigmatic. Animal studies show that the cerebral...

journal_title：Current hypertension reports

authors： Bergman L,Torres-Vergara P,Penny J,Wikström J,Nelander M,Leon J,Tolcher M,Roberts JM,Wikström AK,Escudero C

更新日期：2019-08-02 00:00:00

abstract：PURPOSE OF REVIEW:This review provides a comprehensive insight into the angiogenic profile of hypertensive and normotensive pregnancies compromised by HIV infection. Furthermore, we evaluate the economic implementation of the sFlt-1/PlGF ratio and review the reports on therapeutic apheresis in limiting sFlt-1 productio...

journal_title：Current hypertension reports

authors： Padayachee S,Moodley J,Naicker T

更新日期：2019-07-24 00:00:00

abstract：:Administering relaxin to conscious rats and humans elicits systemic and renal vasodilation. The molecular mechanisms vary according to the duration of relaxin exposure-so-called "rapid" (within minutes) or "sustained" (hours to days) vasodilatory responses-both being endothelium-dependent. Rapid responses are mediated...

journal_title：Current hypertension reports

authors： Conrad KP,Shroff SG

更新日期：2011-12-01 00:00:00

abstract：:Decreased endothelial nitric oxide (NO) bioavailability as it relates to endothelial dysfunction plays an important role in various cardiovascular disorders, including athero-sclerosis. Recent research has provided evidence that endothelial dysfunction in atherosclerosis is not primarily caused by decreased endothelia...

journal_title：Current hypertension reports

authors： Yang Z,Ming XF

更新日期：2006-04-01 00:00:00

abstract：:With current immunosuppression, elevated blood pressure is found in almost 90% of renal graft recipients. Major causes of this are impairment of renal function (secondary to chronic allograft nephropathy or less frequently recurrence of primary renal disease), the use of calcineurin inhibitors as immunosuppressants, u...

journal_title：Current hypertension reports

authors： Schwenger V,Zeier M,Ritz E

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of the study is to perform a critical assessment of in vitro models of pre-eclampsia using complementary human and cell line-based studies. Molecular mechanisms involved in spiral uterine artery (SUA) remodelling and trophoblast functionality will also be discussed. RECENT FINDINGS:A number o...

journal_title：Current hypertension reports

authors： McNally R,Alqudah A,Obradovic D,McClements L

更新日期：2017-10-23 00:00:00

abstract：:Masked hypertension refers to the phenomenon of having a non-elevated clinic blood pressure (BP) despite having an elevated out-of-clinic BP. Masked hypertension is a common phenotype with a cardiovascular risk profile similar to that of sustained hypertension, defined as elevated clinic and out-of-clinic BP. Current ...

journal_title：Current hypertension reports

authors： Anstey DE,Pugliese D,Abdalla M,Bello NA,Givens R,Shimbo D

更新日期：2017-10-25 00:00:00

abstract：:Dual blockade of the renin angiotensin system is based on a principle of obtaining the broadest and most efficient blockade of the effects of angiotensin II, by using the combination of an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II-receptor blocker (ARB). By combining two, different pharmacolo...

journal_title：Current hypertension reports

authors： Andersen NH,Mogensen CE

更新日期：2004-10-01 00:00:00

abstract：:The epithelial sodium channel (ENaC) is a membrane protein made of three different but homologous subunits (a, b, and g) present in the apical membrane of epithelial cells of, for example, the distal nephron. This channel is responsible for salt reabsorption in the kidney and can cause human diseases by increasing cha...

journal_title：Current hypertension reports

authors： Hummler E

更新日期：2003-02-01 00:00:00

abstract：:Hypertension is present in three of four patients with coronary artery disease (CAD) but remains largely uncontrolled in most patients. Treating hypertension in these patients is complicated by the concern of precipitating coronary ischemia when diastolic blood pressure (DBP) is reduced excessively. However, an emergi...

journal_title：Current hypertension reports

authors： Vongpatanasin W

更新日期：2008-10-01 00:00:00

abstract：:Chronic kidney disease is a major public health problem worldwide: it is estimated that in the general population, 1 person in 10 has some degree of renal damage. Adequate blood pressure control represents the mainstay of treatment, to delay deterioration of renal function and prevent cardiovascular complications. Cur...

journal_title：Current hypertension reports

authors： Leoncini G,Viazzi F,Pontremoli R

更新日期：2010-10-01 00:00:00

abstract：:Recent studies have identified key gender differences in cardiovascular function, renal hemodynamics, and the renin-angiotensin system. Extensive epidemiologic evidence has shown a clear gender difference in cardiovascular and renal disease progression, whereby female sex appears to be protective. The mechanisms under...

journal_title：Current hypertension reports

authors： Kang AK,Miller JA

更新日期：2002-04-01 00:00:00