Real-World Strategies to Treat Hypertension Associated with Pediatric Obesity.

abstract：:Elevation of blood pressure (BP) and the risk for progression to hypertension (HTN) is of increasing concern in children and adolescents. Indeed, it is increasingly recognized that target organ injury may begin with even low levels of BP elevation. Sodium intake has long been recognized as a modifiable risk factor for...

journal_title：Current hypertension reports

authors： Hanevold CD

更新日期：2013-10-01 00:00:00

abstract：:The research on molecular genetics of human hypertension aims to identify the loci involved in the regulation of blood pressure, detect gene variants within the identified loci, associate them with intermediate phenotypes, and ultimately estimate their quantitative effects on blood pressure level and their interaction...

journal_title：Current hypertension reports

authors： Jeunemaitre X,Gimenez-Roqueplo AP,Célérier J,Corvol P

更新日期：1999-02-01 00:00:00

abstract：:Heart failure has emerged as one of the most important diseases of the past century. The understanding and treatment of heart failure has evolved significantly over the years. As we move further into the era of device therapy, attention has turned to the idea of sympathetic nervous system modulation through renal dene...

journal_title：Current hypertension reports

authors： Fong MW,Shavelle D,Weaver FA,Nadim MK

更新日期：2015-03-01 00:00:00

abstract：:Diabetes and hypertension are common coexistent conditions, the combination of which results in an increased risk for cardiovascular and renal disease. Clinical trials have convincingly demonstrated the benefit of tight blood pressure control among patients with diabetes in reducing these risks. Furthermore, the choic...

journal_title：Current hypertension reports

authors： Borzecki AM,Berlowitz DR

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes the most recent and innovative implementation strategies for hypertension control in low- and middle-income countries (LMICs). RECENT FINDINGS:Implementation strategies from Latin America, Africa, and Asia were organized across three levels: community, health system, and policy...

journal_title：Current hypertension reports

authors： Mercer T,Nulu S,Vedanthan R

更新日期：2020-05-13 00:00:00

abstract：:Diastolic pressure, systolic pressure, and pulse pressure have all been assigned the role of the best predictor of cardiovascular events during the 20th century. At the dawn of the new millennium, concepts that draw attention to vascular mechanics reconcile the seemingly conflicting results of epidemiologic studies, b...

journal_title：Current hypertension reports

authors： Vlachopoulos C,O'Rourke M

更新日期：2000-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The overactive renin-angiotensin-aldosterone system (RAAS) plays an important part in many pathologic conditions including hypertension, heart failure, and renal disease. Hyperkalemia, a potentially life-threatening side effect of RAAS inhibitors, limits their use. The recent introduction of new hyper...

journal_title：Current hypertension reports

authors： Rastogi A,Arman F,Alipourfetrati S

更新日期：2016-07-01 00:00:00

abstract：:Recent guidelines for the treatment of hypertension place great emphasis on tighter blood pressure control, especially in the presence of hypertensive target organ damage and diabetes. In order to achieve these treatment targets, more patients will require a combination of antihypertensive medications. However, resist...

journal_title：Current hypertension reports

authors： Felmeden DC,Lip GY

更新日期：2001-06-01 00:00:00

abstract：:The ubiquitin-proteasome system (UPS) is a major proteolytic system that regulates the degradation of intracellular proteins in the heart. The UPS regulates the turnover of misfolded and damaged proteins, in addition to numerous cellular processes, by affecting the stability of short-lived proteins such as transcripti...

journal_title：Current hypertension reports

authors： Rodríguez JE,Schisler JC,Patterson C,Willis MS

更新日期：2009-12-01 00:00:00

abstract：:The fact that cardiovascular risk factors cluster among individuals with the insulin resistance syndrome strongly suggests a common pathogenetic denominator. For many years, abnormalities of nonesterified fatty acid metabolism have been implicated in the disturbances of carbohydrate and lipid metabolism that character...

journal_title：Current hypertension reports

authors： Egan BM,Greene EL,Goodfriend TL

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to systematically review existing evidence on the effectiveness of mobile health technology (mHealth) interventions in addressing medication adherence among people with hypertension. RECENT FINDINGS:Twenty-one studies of mHealth interventions were included in the final review after sy...

journal_title：Current hypertension reports

authors： Xiong S,Berkhouse H,Schooler M,Pu W,Sun A,Gong E,Yan LL

更新日期：2018-08-07 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension remains to be a major contributor to global morbidity and mortality. Despite a plethora of pharmacological options available, an abundance of patients have uncontrolled blood pressure thus creating the need for additional strategies, including non-pharmacologic approaches. In this review,...

journal_title：Current hypertension reports

authors： Cernes R,Zimlichman R

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To review latest reports of the food products which might increase blood pressure and therefore might participate in the pathogenesis of hypertension. RECENT FINDINGS:Results of clinical study suggest that consumption of high-sodium food leads to transient increase in plasma sodium concentration. Thi...

journal_title：Current hypertension reports

authors： Adamczak M,Wiecek A

更新日期：2020-01-08 00:00:00

abstract：:Sympathetic nerve activity is involved in the pathogenesis of salt-sensitive hypertension. The central nervous system, which regulates sympathetic nerve activity and blood pressure, plays a pivotal role. Central sympathoexcitation is deeply involved in the pathogenesis of salt-sensitive hypertension, although the prec...

journal_title：Current hypertension reports

authors： Fujita M,Fujita T

更新日期：2016-02-01 00:00:00

abstract：:To further understand chronic heart disease, such as heart failure and cardiomyopathy, we must fully define signaling pathways within the myocardium. Recent studies suggest that some forms of heart disease are associated with a chronic low-grade inflammation that promotes adverse ventricular remodeling and correlates ...

journal_title：Current hypertension reports

authors： Ahn J,Kim J

更新日期：2012-12-01 00:00:00

abstract：:Inflammation plays an important role in the pathogenesis of hypertension. Innate and adaptive immune response may contribute to this process. The mechanisms implicating immune response in hypertension are still elusive. To date, the evidence originates in three major areas of data: cytokine production, central nervous...

journal_title：Current hypertension reports

authors： Leibowitz A,Schiffrin EL

更新日期：2011-12-01 00:00:00

abstract：:Excess weight gain is a major cause of essential hypertension, and abnormal kidney function appears to be a cause as well as a consequence of obesity hypertension. Excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role in mediating increased blood pressure associated with w...

journal_title：Current hypertension reports

authors： Hall JE

更新日期：2000-04-01 00:00:00

abstract：:Salt-sensitive hypertension is closely related with natriuretic capacity of the kidney. Besides several genome-wide research reported candidate gene or gene polymorphism responsible for salt-sensitive hypertension, recently, several new factors for acquired salt-sensitive hypertension are reported. Among them, we have...

journal_title：Current hypertension reports

authors： Shimosawa T,Mu S,Shibata S,Fujita T

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This article introduces the haemodynamic principles that underpin the pathophysiology of hypertension and introduces a rational physiological approach to appropriate pharmacologic treatment. RECENT FINDINGS:Outdated understanding of haemodynamics based on previous measurement systems can no longer be...

journal_title：Current hypertension reports

authors： Smith BE,Madigan VM

更新日期：2018-04-10 00:00:00

abstract：:Hypertension (especially systolic hypertension) is very common in older persons. Systolic hypertension occurs because large conduit arteries become stiffer with age. Strong evidence from randomized trials suggests that treating systolic blood pressures initially higher than 160 mm Hg is extremely beneficial, and a rec...

journal_title：Current hypertension reports

authors： Hyman DJ,Taffet GE

更新日期：2009-10-01 00:00:00

abstract：:When a large multicenter research trial is abruptly terminated, it is usually a consequence of significant adverse events. In contrast, when the Randomized Aldactone Evaluation Study (RALES) mortality trial was discontinued 18 months early, it was because of the prominent salutary effect of spironolactone, added to st...

journal_title：Current hypertension reports

authors： Soberman JE,Weber KT

更新日期：2000-10-01 00:00:00

abstract：:Circulating angiotensin II (Ang II) combined with high salt intake increases sympathetic nerve activity (SNA) in some forms of hypertension. Ang II-induced increases in SNA are modest, delayed, and specific to certain vascular beds. The brain targets for circulating Ang II are neurons in the area postrema (AP), subfor...

journal_title：Current hypertension reports

authors： Osborn JW,Fink GD,Sved AF,Toney GM,Raizada MK

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Do dietary fats lower blood pressure? This review covers total fats, individual fatty acids and foods that provide specific fats. RECENT FINDINGS:Evidence for blood pressure lowering is stronger for supplements providing individual marine fatty acids than for fish intake since data on fish consumptio...

journal_title：Current hypertension reports

authors： Nestel PJ

更新日期：2019-02-12 00:00:00

abstract：:Current national guidelines recommend aggressive lowering of blood pressure (< 130/80 mm Hg) in patients with chronic kidney disease (CKD). In this paper, we summarize recent clinical trial data evaluating the effect of lower blood pressure goals on renal outcomes. The epidemiologic data relating blood pressure to pro...

journal_title：Current hypertension reports

authors： Rahman M,El-Meanawy A,Romanello J

更新日期：2005-10-01 00:00:00

abstract：:Patients with hypertension have a high prevalence of concurrent metabolic abnormalities (eg, obesity, dyslipidemia, and hyperglycemia). Clustering of these risk factors, defined as the metabolic syndrome, is associated with a high cardiovascular risk profile. This review summarizes current knowledge about the prevalen...

journal_title：Current hypertension reports

authors： Fallo F,Federspil G,Veglio F,Mulatero P

更新日期：2007-04-01 00:00:00

abstract：:Masked hypertension refers to the phenomenon of having a non-elevated clinic blood pressure (BP) despite having an elevated out-of-clinic BP. Masked hypertension is a common phenotype with a cardiovascular risk profile similar to that of sustained hypertension, defined as elevated clinic and out-of-clinic BP. Current ...

journal_title：Current hypertension reports

authors： Anstey DE,Pugliese D,Abdalla M,Bello NA,Givens R,Shimbo D

更新日期：2017-10-25 00:00:00

abstract：PURPOSE OF THE REVIEW:The purpose of this review is to highlight the clinical significance of increased renal risk that has its origins in fetal life. This review will also discuss the critical need to identify therapeutic interventions for use in a pregnancy complicated by placental dysfunction and intrauterine growth...

journal_title：Current hypertension reports

authors： Coats LE,Davis GK,Newsome AD,Ojeda NB,Alexander BT

更新日期：2019-06-21 00:00:00

abstract：:We are used to thinking of angiotensin (Ang) II as a regulatory hormone that stimulates constriction of vascular smooth muscle cells, aldosterone release from the adrenal gland, and sodium reabsorption in the renal tubule. We have also become accustomed to understanding that Ang II may be formed and may act locally as...

journal_title：Current hypertension reports

authors： Luft FC

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This meta-analysis and systematic review was conducted to evaluate the effect of probiotics on blood pressure, body mass index (BMI), and blood glucose changes in patients with hypertension. RECENT FINDINGS:We searched the PubMed, Cochrane, Embase, and ProQuest databases using a combination of MeSH a...

journal_title：Current hypertension reports

authors： Chi C,Li C,Wu D,Buys N,Wang W,Fan H,Sun J

更新日期：2020-03-21 00:00:00

abstract：PURPOSE OF REVIEW:This review is intended to briefly describe the primary mechanistic pathways by which several common drugs can increase blood pressure. We also propose potential management strategies based on the underlying mechanisms responsible for the blood pressure elevation. RECENT FINDINGS:As hypertension is a...

journal_title：Current hypertension reports

authors： Lovell AR,Ernst ME

更新日期：2017-05-01 00:00:00