Nonesterified fatty acids in blood pressure control and cardiovascular complications.

abstract：:Antiplatelet agents represent a cornerstone in the management of patients at increased cardiovascular risk. Essential hypertension is considered a major public health problem leading to increased cardiovascular morbidity and mortality. The majority of patients with essential hypertension exhibit also additional cardio...

journal_title：Current hypertension reports

authors： Gkaliagkousi E,Gavriilaki E,Douma S

更新日期：2015-04-01 00:00:00

abstract：:With the cut-off point between "normal" and "high" blood pressure (BP) being pushed increasingly downward, especially for patients with multiple cardiovascular risk factors, most hypertensives need more than one antihypertensive agent to reach their target BP. In this article, we examine the rationale for combining dr...

journal_title：Current hypertension reports

authors： Gavras I,Rosenthal T

更新日期：2004-08-01 00:00:00

abstract：:The obesity gene product leptin plays an important role in the physiologic regulation of appetite and energy balance. Plasma leptin levels correlate closely with body fat storage and may respond to changes in energy expenditure. Recent evidence has implicated a direct cardiac regulatory action of leptin in addition to...

journal_title：Current hypertension reports

authors： Ren J,Ma H

更新日期：2008-12-01 00:00:00

abstract：:There are many drug studies for the treatment of hypertension. Most studies compare one drug with another to determine if a drug or class of drugs have unique benefits. In evaluating drug trials, separation of hypertension as compared with atherosclerotic events is important. Trials that focus on prevention of hyperte...

journal_title：Current hypertension reports

authors： Kuller LH

更新日期：1999-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review is intended to briefly describe the primary mechanistic pathways by which several common drugs can increase blood pressure. We also propose potential management strategies based on the underlying mechanisms responsible for the blood pressure elevation. RECENT FINDINGS:As hypertension is a...

journal_title：Current hypertension reports

authors： Lovell AR,Ernst ME

更新日期：2017-05-01 00:00:00

abstract：:Hypertension is a preventable condition, and the outcomes of clinical trials have established that its treatment reduces cardiovascular morbidity and mortality. Although awareness about the disease has improved in the past two decades, the reality is that many people remain untreated or not adequately controlled. The ...

journal_title：Current hypertension reports

authors： Nunes MI

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In chronic kidney disease (CKD), plasma uric acid levels are increased because of the decrease in glomerular filtration rate. However, in addition to CKD, hyperuricemia is frequently associated with a number of other conditions such as hypertension, type 2 diabetes, obesity, and heart failure, overwei...

journal_title：Current hypertension reports

authors： Kielstein JT,Pontremoli R,Burnier M

更新日期：2020-10-31 00:00:00

abstract：:Vascular changes associated with elevated blood pressure may precede the clinical diagnosis of hypertension. Even after the diagnosis is made, associated coronary heart disease and renal disease continue to progress, despite adequate blood pressure control. Early treatment of blood pressure may reduce the incidence of...

journal_title：Current hypertension reports

authors： Nesbitt SD,Julius S

更新日期：2000-08-01 00:00:00

abstract：:Elevation of blood pressure (BP) and the risk for progression to hypertension (HTN) is of increasing concern in children and adolescents. Indeed, it is increasingly recognized that target organ injury may begin with even low levels of BP elevation. Sodium intake has long been recognized as a modifiable risk factor for...

journal_title：Current hypertension reports

authors： Hanevold CD

更新日期：2013-10-01 00:00:00

abstract：:The metabolic syndrome leads to cardiovascular disease and type 2 diabetes mellitus, through multiple risks, such as insulin resistance, dyslipidemia, hyperinsulinemia, and hypertension. It also represents a disorder of partial genetic background as mutations of the peroxisome proliferator-activated receptor-gamma (PP...

journal_title：Current hypertension reports

authors： Tuck ML

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this meta-analysis was to compare the magnitude of systematic bias (mean difference) and random error (standard deviation of mean difference) between the cuff method of indirect blood pressure and directly measured intra-arterial pressure. RECENT FINDINGS:Blood pressure is almost exclu...

journal_title：Current hypertension reports

authors： Dankel SJ,Kang M,Abe T,Loenneke JP

更新日期：2019-02-07 00:00:00

abstract：:There is increasing concern that sugar consumption may be linked to the development of metabolic and cardiovascular diseases. There is indeed strong evidence that consumption of energy-dense sugary beverages and foods is associated with increased energy intake and body weight gain over time. It is further proposed tha...

journal_title：Current hypertension reports

authors： Rosset R,Surowska A,Tappy L

更新日期：2016-06-01 00:00:00

abstract：:Resistant hypertension is defined as blood pressure that remains uncontrolled despite using at least three antihypertensive medications in effective doses, ideally including a diuretic. Stricter blood pressure goals, higher obesity rates, older age, and increased use of certain exogenous substances are related to an i...

journal_title：Current hypertension reports

authors： Pimenta E,Calhoun DA

更新日期：2007-11-01 00:00:00

abstract：:The sodium pump, an ancestral enzyme with conserved ability to bind ouabain, plays a key role in salt conservation and is regulated by aldosterone and endogenous ouabain (EO). Plasma EO is elevated in about 45% of patients with essential hypertension and correlates with blood pressure. The relationship of EO with Na(+...

journal_title：Current hypertension reports

authors： Hamlyn JM,Manunta P

更新日期：2011-02-01 00:00:00

abstract：:The discovery of angiotensin-converting enzyme (ACE) 2 adds a new level of complexity to the understanding of the renin-angiotensin system. The high catalytic efficiency of ACE2 for the generation of angiotensin (ANG)-1-7 from ANG II suggests an important role of ACE2 in preventing ANG II accumulation, while at the sa...

journal_title：Current hypertension reports

authors： Wysocki J,González-Pacheco FR,Batlle D

更新日期：2008-02-01 00:00:00

abstract：:Hypertension (HTN) is the most common modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality worldwide. Lower- and middle-income countries (LMICs) are projected to bear the vast majority of this disease burden, but local and regional health care delivery systems in these countries are ill equi...

journal_title：Current hypertension reports

authors： Brody AM,Kumar VA,Levy PD

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine available clinical data on the differences between premenopausal and postmenopausal women with hypertension (HTN). Clinical conditions related to HTN and reproductive status differ in younger women compared with older women. Due to recent changes in the definition of HTN, the prevalence of ...

journal_title：Current hypertension reports

authors： Brahmbhatt Y,Gupta M,Hamrahian S

更新日期：2019-08-26 00:00:00

abstract：:Hypertension is an important public health problem, and increasingly children are being diagnosed with primary hypertension. As the list of secondary causes of hypertension is extensive, pediatric practitioners increasingly need to decide on investigations needed for evaluating children presenting with high blood pres...

journal_title：Current hypertension reports

authors： Kapur G,Baracco R

更新日期：2013-10-01 00:00:00

abstract：:Hypertension is a major cause of morbidity and mortality worldwide. Despite a myriad of oral agents, many patients fail to reach their target blood pressure. Electrical stimulation of the carotid sinus, an old therapeutic concept, lowers blood pressure by initiating the baroreflex and reducing sympathetic tone. Recent...

journal_title：Current hypertension reports

authors： Filippone JD,Sloand JA,Illig KA,Bisognano JD

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension remains to be a major contributor to global morbidity and mortality. Despite a plethora of pharmacological options available, an abundance of patients have uncontrolled blood pressure thus creating the need for additional strategies, including non-pharmacologic approaches. In this review,...

journal_title：Current hypertension reports

authors： Cernes R,Zimlichman R

更新日期：2017-06-01 00:00:00

abstract：:Epinephrine is the prototypical stress hormone. Its stimulation of all α and β adrenergic receptors elicits short-term systolic hypertension, hyperglycemia, and other aspects of the metabolic syndrome. Acute epinephrine infusion increases cardiac output and induces insulin resistance, but removal of the adrenal medull...

journal_title：Current hypertension reports

authors： Ziegler MG,Elayan H,Milic M,Sun P,Gharaibeh M

更新日期：2012-02-01 00:00:00

abstract：:Primary aldosteronism is commonly regarded as largely sporadic, but both germline and somatic mutations are increasingly recognized as underlying the condition. Three germline mutations causing familial hyperaldosteronism have been described, dubbed FH I (due to a CYP11B1/CYP11B2 chimera), FH II (localized to chromoso...

journal_title：Current hypertension reports

authors： Funder JW

更新日期：2012-04-01 00:00:00

abstract：:Aldosterone antagonists have been highly successful in treating congestive heart failure and resistant hypertension. Until recently, therapies targeting the mineralocorticoid receptor in chronic kidney disease (CKD) have received little attention, largely because of the risk of hyperkalemia and the incorrect assumptio...

journal_title：Current hypertension reports

authors： Volk MJ,Bomback AS,Klemmer PJ

更新日期：2011-08-01 00:00:00

abstract：:Resistant hypertension is a common and growing clinical problem characterized by failure to achieve target blood pressure levels despite adequate use of at least three antihypertensive agents. Although numerous safe and effective pharmacologic therapies are available to treat elevated blood pressure, novel therapeutic...

journal_title：Current hypertension reports

authors： Schlaich MP,Krum H,Esler MD

更新日期：2010-08-01 00:00:00

abstract：:Administering relaxin to conscious rats and humans elicits systemic and renal vasodilation. The molecular mechanisms vary according to the duration of relaxin exposure-so-called "rapid" (within minutes) or "sustained" (hours to days) vasodilatory responses-both being endothelium-dependent. Rapid responses are mediated...

journal_title：Current hypertension reports

authors： Conrad KP,Shroff SG

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the current literature on use of telehealth at different stages of the hypertension control cascade in sub-Saharan Africa (SSA) and to discuss opportunities to harness technology infrastructure in SSA to improve population-level blood pressure control. RECENT FINDINGS:Despite the high burde...

journal_title：Current hypertension reports

authors： Muiruri C,Manavalan P,Jazowski SA,Knettel BA,Vilme H,Zullig LL

更新日期：2019-08-26 00:00:00

abstract：:The various antihypertensive regimens have varying effects on glucose metabolism and the development of diabetes mellitus. Recent large hypertension trials have shown great differences in the development of new-onset diabetes among antihypertensive drug therapies. The incidence of diabetes is unchanged or increased by...

journal_title：Current hypertension reports

authors： Aksnes TA,Reims HM,Kjeldsen SE,Mancia G

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review data supporting the use of home blood pressure monitoring (HBPM) and provide practical guidance to clinicians wishing to incorporate HBPM into their practice. RECENT FINDINGS:HBPM more accurately reflects the risk of cardiovascular events than office blood pressure measurement. In addition,...

journal_title：Current hypertension reports

authors： Liyanage-Don N,Fung D,Phillips E,Kronish IM

更新日期：2019-02-12 00:00:00

abstract：:Young hypertensive adults demonstrate decreased performance on neurocognitive testing compared with that of normotensive controls. There is emerging, preliminary evidence that children with hypertension also manifest cognitive differences when compared to normotensive controls. These preliminary studies consist mostly...

journal_title：Current hypertension reports

authors： Lande MB,Kupferman JC

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This meta-analysis and systematic review was conducted to evaluate the effect of probiotics on blood pressure, body mass index (BMI), and blood glucose changes in patients with hypertension. RECENT FINDINGS:We searched the PubMed, Cochrane, Embase, and ProQuest databases using a combination of MeSH a...

journal_title：Current hypertension reports

authors： Chi C,Li C,Wu D,Buys N,Wang W,Fan H,Sun J

更新日期：2020-03-21 00:00:00