Effectiveness of mHealth Interventions in Improving Medication Adherence Among People with Hypertension: a Systematic Review.

Abstract:

PURPOSE OF REVIEW:This study aims to systematically review existing evidence on the effectiveness of mobile health technology (mHealth) interventions in addressing medication adherence among people with hypertension. RECENT FINDINGS:Twenty-one studies of mHealth interventions were included in the final review after systematic searching and screening of publications from 2000 to 2017 in PubMed, Web of Science, and Embase. Key features of the mHealth interventions include high intervention intensity, multifactorial components, and patient-centered approaches with tailored content and interaction. All studies found tendencies to improvement in medication adherence, but only 12 studies reported that the improvements were statistically significant in the intervention groups compared with the control groups. Twelve studies also found that mHealth interventions were beneficial for blood pressure control. None of the studies was conducted in a low-income country. Our systematic review found evidence that mHealth interventions improved medication adherence and blood pressure control among people with hypertension. However, most studies were small in sample size and short in study duration, and not all results were statistically significant. Future research should focus on investigating the sustainability and generalizability of mHealth interventions.

journal_name

Curr Hypertens Rep

authors

Xiong S,Berkhouse H,Schooler M,Pu W,Sun A,Gong E,Yan LL

doi

10.1007/s11906-018-0886-7

subject

Has Abstract

pub_date

2018-08-07 00:00:00

pages

86

issue

10

eissn

1522-6417

issn

1534-3111

pii

10.1007/s11906-018-0886-7

journal_volume

20

pub_type

杂志文章
  • Spironolactone in congestive heart failure.

    abstract::When a large multicenter research trial is abruptly terminated, it is usually a consequence of significant adverse events. In contrast, when the Randomized Aldactone Evaluation Study (RALES) mortality trial was discontinued 18 months early, it was because of the prominent salutary effect of spironolactone, added to st...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-000-0027-x

    authors: Soberman JE,Weber KT

    更新日期:2000-10-01 00:00:00

  • Dysfunctional brain-bone marrow communication: a paradigm shift in the pathophysiology of hypertension.

    abstract::It is widely accepted that the pathophysiology of hypertension involves autonomic nervous system dysfunction, as well as a multitude of immune responses. However, the close interplay of these systems in the development and establishment of high blood pressure and its associated pathophysiology remains elusive and is t...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-013-0361-4

    authors: Santisteban MM,Zubcevic J,Baekey DM,Raizada MK

    更新日期:2013-08-01 00:00:00

  • Ongoing trials: what should we expect after ALLHAT?

    abstract::The publication of the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, when used in conjunction with a new meta-analysis, provides hypertension research with a watershed. Data demonstrate clearly that lowering blood pressure is the most important aspect of hypertension man...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,meta分析

    doi:10.1007/s11906-003-0044-7

    authors: Wang JG,Staessen JA,Heagerty AM

    更新日期:2003-08-01 00:00:00

  • Using health information technology to improve hypertension management.

    abstract::High-quality medical care requires implementing evidence-based best practices, with continued monitoring to improve performance. Implementation science is beginning to identify approaches to developing, implementing, and evaluating quality improvement strategies across health care systems that lead to good outcomes fo...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-008-0038-6

    authors: Goldstein MK

    更新日期:2008-06-01 00:00:00

  • Management of hypertension in patients with coronary artery disease.

    abstract::Hypertension is present in three of four patients with coronary artery disease (CAD) but remains largely uncontrolled in most patients. Treating hypertension in these patients is complicated by the concern of precipitating coronary ischemia when diastolic blood pressure (DBP) is reduced excessively. However, an emergi...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-008-0066-2

    authors: Vongpatanasin W

    更新日期:2008-10-01 00:00:00

  • Hypertension after renal transplantation.

    abstract::With current immunosuppression, elevated blood pressure is found in almost 90% of renal graft recipients. Major causes of this are impairment of renal function (secondary to chronic allograft nephropathy or less frequently recurrence of primary renal disease), the use of calcineurin inhibitors as immunosuppressants, u...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-001-0063-1

    authors: Schwenger V,Zeier M,Ritz E

    更新日期:2001-10-01 00:00:00

  • Drug-Induced Hypertension: Focus on Mechanisms and Management.

    abstract:PURPOSE OF REVIEW:This review is intended to briefly describe the primary mechanistic pathways by which several common drugs can increase blood pressure. We also propose potential management strategies based on the underlying mechanisms responsible for the blood pressure elevation. RECENT FINDINGS:As hypertension is a...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-017-0736-z

    authors: Lovell AR,Ernst ME

    更新日期:2017-05-01 00:00:00

  • The kidney and hypertension: pathogenesis of salt-sensitive hypertension.

    abstract::Salt-sensitive hypertension is closely related with natriuretic capacity of the kidney. Besides several genome-wide research reported candidate gene or gene polymorphism responsible for salt-sensitive hypertension, recently, several new factors for acquired salt-sensitive hypertension are reported. Among them, we have...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-012-0284-5

    authors: Shimosawa T,Mu S,Shibata S,Fujita T

    更新日期:2012-10-01 00:00:00

  • Selective vs. Global Renal Denervation: a Case for Less Is More.

    abstract:PURPOSE OF REVIEW:Review the renal nerve anatomy and physiology basics and explore the concept of global vs. selective renal denervation (RDN) to uncover some of the fundamental limitations of non-targeted renal nerve ablation and the potential superiority of selective RDN. RECENT FINDINGS:Recent trials testing the ef...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-018-0838-2

    authors: Fudim M,Sobotka AA,Yin YH,Wang JW,Levin H,Esler M,Wang J,Sobotka PA

    更新日期:2018-05-01 00:00:00

  • Renin receptor blockade: a better strategy for renal protection than renin-angiotensin system inhibition?

    abstract::Prorenin and renin bind to a 350-amino acid protein called the (pro)renin receptor, which is present on the surface and functions intracellularly. When the receptor's N terminus binds either prorenin or renin, intracellular signaling occurs via extracellular-regulated kinases, which can result in plasminogen activator...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-008-0075-1

    authors: Müller DN,Luft FC

    更新日期:2008-10-01 00:00:00

  • From Clinical Trials to Bedside: the Use of Antihypertensives in Aged Individuals. Part 2: Approach to Treatment.

    abstract:PURPOSE OF REVIEW:Use of antihypertensives in older adults can be complicated by the potential for undesired effects on comorbidities, adverse effects of the drugs, and overall medication burden. The purpose of this two-part review is to discuss contemporary issues encountered in the management of hypertension in aged ...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-019-0988-x

    authors: Ernst ME,MacLaughlin EJ

    更新日期:2019-10-10 00:00:00

  • Vasopeptidase inhibition and endothelial function in hypertension.

    abstract::Vasopeptidase inhibitors are a new class of drugs capable of inhibiting both angiotensin-converting enzyme and neutral endopeptidase 24.11. This involves simultaneous inhibition with a single molecule of two key enzymes, ACE and NEP, which are both involved in the regulation of cardiovascular homeostasis in many ways....

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-001-0101-z

    authors: d'Uscio LV,Lüscher TF

    更新日期:2001-12-01 00:00:00

  • Implementing Home Blood Pressure Monitoring into Clinical Practice.

    abstract:PURPOSE OF REVIEW:To review data supporting the use of home blood pressure monitoring (HBPM) and provide practical guidance to clinicians wishing to incorporate HBPM into their practice. RECENT FINDINGS:HBPM more accurately reflects the risk of cardiovascular events than office blood pressure measurement. In addition,...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-019-0916-0

    authors: Liyanage-Don N,Fung D,Phillips E,Kronish IM

    更新日期:2019-02-12 00:00:00

  • Systemic blood pressure and stroke outcome and recurrence.

    abstract::Although it is clear that hypertension is a primary cause of stroke, there has been controversy concerning blood pressure management after stroke. Recent studies indicate that lowering systemic blood pressure after stroke reduces the risk for recurrent stroke or vascular events, but other studies provide evidence that...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-005-0058-4

    authors: Hillis AE

    更新日期:2005-02-01 00:00:00

  • Postmenopausal hypertension.

    abstract::Cardiovascular disease is the leading cause of death in women and claims the lives of more than half a million women every year. Hypertension is one of the most prevalent and powerful contributors to atherosclerotic cardiovascular disease. Hypertension affects more men than women until 55 years of age, but after age 5...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-000-0083-2

    authors: Harrison-Bernard LM,Raij L

    更新日期:2000-04-01 00:00:00

  • Renin inhibitors: optimal strategy for renal protection.

    abstract::Diabetic nephropathy and hypertension are the major causes of chronic kidney disease. The renin system plays a key role in the control of blood pressure (BP), as well as in the regulation of renal and adrenal function. Chronic activation of the renin system can lead to organ damage, particularly renal damage; increasi...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-007-0076-5

    authors: Schmieder RE

    更新日期:2007-11-01 00:00:00

  • A Meta-analysis to Determine the Validity of Taking Blood Pressure Using the Indirect Cuff Method.

    abstract:PURPOSE OF REVIEW:The purpose of this meta-analysis was to compare the magnitude of systematic bias (mean difference) and random error (standard deviation of mean difference) between the cuff method of indirect blood pressure and directly measured intra-arterial pressure. RECENT FINDINGS:Blood pressure is almost exclu...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,meta分析

    doi:10.1007/s11906-019-0929-8

    authors: Dankel SJ,Kang M,Abe T,Loenneke JP

    更新日期:2019-02-07 00:00:00

  • Biomarkers in hypertension and their relationship with myocardial target-organ damage.

    abstract::Essential hypertension is a very common health condition that is associated with an array of long-term end-organ diseases, including premature cardiovascular disease. Currently, there is no effective method to identify high-risk patients who may develop cardiovascular comorbidities in the future. Clinically, it would ...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-014-0502-4

    authors: Xue Y,Iqbal N,Chan J,Maisel A

    更新日期:2014-12-01 00:00:00

  • Assessment of cardiovascular risk.

    abstract::Atherosclerotic cardiovascular disease (CVD) is the most common cause of death worldwide. Usually atherosclerosis is caused by the combined effects of multiple risk factors. For this reason, most guidelines on the prevention of CVD stress the assessment of total CVD risk. The most intensive risk factor modification ca...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-010-0143-1

    authors: Cooney MT,Cooney HC,Dudina A,Graham IM

    更新日期:2010-10-01 00:00:00

  • Insulin resistance in HIV-related lipodystrophy.

    abstract::Lipodystrophy (LD) associated with HIV infection is a syndrome of abnormal fat distribution observed in HIV-infected patients treated with various antiretroviral agents. In addition, insulin resistance and dyslipidemia can occur in HIV-infected patients with or without LD. The demonstration of the latter metabolic dis...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-003-0067-0

    authors: Mikhail N

    更新日期:2003-04-01 00:00:00

  • Is population-wide diuretic use directly associated with the incidence of end-stage renal disease in the United States?

    abstract::In the quest for "evidence-based" medicine, an accepted hierarchy of evidence has been proposed. This hierarchy places in vitro studies and animal data at the base, and puts systematic reviews, meta-analyses, and randomized controlled trials at the pinnacle. However, when clinical medicine faces questions that have no...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-006-0054-3

    authors: Hawkins RG

    更新日期:2006-06-01 00:00:00

  • Effects of Intrauterine Growth Restriction and Female Sex on Future Blood Pressure and Cardiovascular Disease.

    abstract:PURPOSE OF THE REVIEW:It is well-established that the age-related increase in blood pressure is augmented after menopause. Yet, the prevalence of hypertension is enhanced in low birth weight women relative to normal birth weight counterparts by 60 years of age suggesting that adverse influences during fetal life height...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-017-0712-7

    authors: Davis GK,Newsome AD,Ojeda NB,Alexander BT

    更新日期:2017-02-01 00:00:00

  • The metabolic syndrome in primary aldosteronism.

    abstract::Patients with hypertension have a high prevalence of concurrent metabolic abnormalities (eg, obesity, dyslipidemia, and hyperglycemia). Clustering of these risk factors, defined as the metabolic syndrome, is associated with a high cardiovascular risk profile. This review summarizes current knowledge about the prevalen...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-007-0019-1

    authors: Fallo F,Federspil G,Veglio F,Mulatero P

    更新日期:2007-04-01 00:00:00

  • Renal nerves in the maintenance of hypertension: a potential therapeutic target.

    abstract::Renal sympathetic efferent and afferent nerves, which lie within and immediately adjacent to the wall of the renal arteries, contribute to the maintenance of hypertension. Because the causative factors of hypertension change over time, denervation of both efferent and afferent renal nerves should result in long-term a...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-010-0108-4

    authors: Katholi RE,Rocha-Singh KJ,Goswami NJ,Sobotka PA

    更新日期:2010-06-01 00:00:00

  • Pathophysiology and medical management of systemic hypertension in preeclampsia.

    abstract::Hypertension that complicates preeclampsia in pregnancy is a disorder that requires special consideration in both prevention and pharmacologic treatment. In recent years, few advances have been made regarding the pathophysiology and prevention of preeclampsia; however, there have been some promising results from studi...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-006-0030-y

    authors: Frishman WH,Veresh M,Schlocker SJ,Tejani N

    更新日期:2006-12-01 00:00:00

  • Resistant hypertension and the Birmingham Hypertension Square.

    abstract::Recent guidelines for the treatment of hypertension place great emphasis on tighter blood pressure control, especially in the presence of hypertensive target organ damage and diabetes. In order to achieve these treatment targets, more patients will require a combination of antihypertensive medications. However, resist...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-001-0039-1

    authors: Felmeden DC,Lip GY

    更新日期:2001-06-01 00:00:00

  • The role of the sympathetic nervous system in obesity-related hypertension.

    abstract::Obesity is recognized as a major health problem throughout the world. Excess weight is a major cause of increased blood pressure in most patients with essential hypertension and greatly increases the risk for diabetes, cardiovascular diseases, and end-stage renal disease. Although the mechanisms by which obesity raise...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-009-0036-3

    authors: da Silva AA,do Carmo J,Dubinion J,Hall JE

    更新日期:2009-06-01 00:00:00

  • Effects of antihypertensive treatment on endothelial function.

    abstract::Essential hypertension is characterized by endothelial dysfunction due to reduced availability of nitric oxide (NO) secondary to increased generation of oxygen-free radicals. Some antihypertensive drugs may improve or restore endothelial function independently of their blood pressure lowering effect. The newer generat...

    journal_title:Current hypertension reports

    pub_type: 杂志文章

    doi:10.1007/s11906-011-0207-x

    authors: Virdis A,Ghiadoni L,Taddei S

    更新日期:2011-08-01 00:00:00

  • Epidemiology of pulmonary arterial hypertension.

    abstract::The epidemiology of pulmonary arterial hypertension (PAH) has changed over the last decade. Remarkable advances in understanding the pathobiology and clinical care required in PAH have resulted in improved quality of life and survival. Despite such important progress, the long-term rate of survival is still unacceptab...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-013-0397-5

    authors: Jiang X,Jing ZC

    更新日期:2013-12-01 00:00:00

  • Impaired cardiac function in leptin-deficient mice.

    abstract::The obesity gene product leptin plays an important role in the physiologic regulation of appetite and energy balance. Plasma leptin levels correlate closely with body fat storage and may respond to changes in energy expenditure. Recent evidence has implicated a direct cardiac regulatory action of leptin in addition to...

    journal_title:Current hypertension reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11906-008-0084-0

    authors: Ren J,Ma H

    更新日期:2008-12-01 00:00:00