Low Birth Weight, Blood Pressure and Renal Susceptibility.

abstract：:The prevalence of the metabolic syndrome (MetS) has increased rapidly in North America in recent years. Presently, the MetS is found in 34.3% of the population, and the prevalence is likely to continue to increase in parallel with the obesity epidemic. Losing weight and long-term maintenance of the weight loss are pri...

journal_title：Current hypertension reports

authors： Ferland A,Eckel RH

更新日期：2011-12-01 00:00:00

abstract：:Primary aldosteronism is commonly regarded as largely sporadic, but both germline and somatic mutations are increasingly recognized as underlying the condition. Three germline mutations causing familial hyperaldosteronism have been described, dubbed FH I (due to a CYP11B1/CYP11B2 chimera), FH II (localized to chromoso...

journal_title：Current hypertension reports

authors： Funder JW

更新日期：2012-04-01 00:00:00

abstract：:We are used to thinking of angiotensin (Ang) II as a regulatory hormone that stimulates constriction of vascular smooth muscle cells, aldosterone release from the adrenal gland, and sodium reabsorption in the renal tubule. We have also become accustomed to understanding that Ang II may be formed and may act locally as...

journal_title：Current hypertension reports

authors： Luft FC

更新日期：2001-02-01 00:00:00

abstract：:Insulin resistance (IR) is present in pathologies such as diabetes, obesity, metabolic syndrome, impaired glucose tolerance, hypertension, inflammation, cardiac disease, and dyslipidemias. Population studies show that IR is multifactorial and has genetic components, such as defects in the insulin-signaling pathway (as...

journal_title：Current hypertension reports

authors： Molina MN,Ferder L,Manucha W

更新日期：2016-01-01 00:00:00

abstract：:Hypertension and obesity are two closely related pathologies in clinical practice. Currently, about one billion adults worldwide are overweight, and it is estimated that, if no serious action is taken to effect profound change, that figure will continue to rise throughout this century. Hypertension is also a serious p...

journal_title：Current hypertension reports

authors： Díaz MG,Rusak EJ,Aguilar EA,Bellido CA

更新日期：2014-07-01 00:00:00

abstract：:Our understanding of Na(+) transport defects has exploded in the past several years, and has provided unique insights into epithelial transport processes, and unusual clinical syndromes resulting from mutations of specific ion transporters. These genetic disorders affect Na(+) balance, with both Na(+) retaining and Na...

journal_title：Current hypertension reports

authors： Warnock DG

更新日期：1999-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This meta-analysis and systematic review was conducted to evaluate the effect of probiotics on blood pressure, body mass index (BMI), and blood glucose changes in patients with hypertension. RECENT FINDINGS:We searched the PubMed, Cochrane, Embase, and ProQuest databases using a combination of MeSH a...

journal_title：Current hypertension reports

authors： Chi C,Li C,Wu D,Buys N,Wang W,Fan H,Sun J

更新日期：2020-03-21 00:00:00

abstract：:LCZ696 is a single molecule which combines the angiotensin receptor blocker valsartan with the neprilysn inhibitor sacubitril (AHU377). In the recently published PARADIGM-HF trial, LCZ696 proved superior to enalapril in reducing overall mortality, heart failure hospitalizations, and other endpoints in patients with sy...

journal_title：Current hypertension reports

authors： Gradman AH

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes the most recent and innovative implementation strategies for hypertension control in low- and middle-income countries (LMICs). RECENT FINDINGS:Implementation strategies from Latin America, Africa, and Asia were organized across three levels: community, health system, and policy...

journal_title：Current hypertension reports

authors： Mercer T,Nulu S,Vedanthan R

更新日期：2020-05-13 00:00:00

abstract：PURPOSE OF REVIEW:We focus on the current understanding of preeclampsia (PE) in order to examine how it mediates glomerular injury and affects the course of glomerulonephritis (GNs). In addition, this review discusses the role of GNs on the development of PE. RECENT FINDINGS:In PE, the dysfunctional utero-placental pe...

journal_title：Current hypertension reports

authors： Di Leo V,Capaccio F,Gesualdo L

更新日期：2020-03-21 00:00:00

abstract：:Nitric oxide is involved in the regulation of resting vascular tone, adaptation of blood flow to metabolic demand of tissue, and adaptation of vessel diameter to volume of inflow, ie, flow-mediated dilation. Arterial hypertension is associated with an increased vascular tone of resistance vessels, a reduced compliance...

journal_title：Current hypertension reports

authors： Kelm M

更新日期：2003-02-01 00:00:00

abstract：:Young hypertensive adults demonstrate decreased performance on neurocognitive testing compared with that of normotensive controls. There is emerging, preliminary evidence that children with hypertension also manifest cognitive differences when compared to normotensive controls. These preliminary studies consist mostly...

journal_title：Current hypertension reports

authors： Lande MB,Kupferman JC

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this meta-analysis is to compare the effects of moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) on blood pressure of hypertensive individuals. RECENT FINDINGS:Continuous aerobic training programs are successful in health promotion and are effec...

journal_title：Current hypertension reports

authors： Leal JM,Galliano LM,Del Vecchio FB

更新日期：2020-03-03 00:00:00

abstract：:Diabetes mellitus is well recognized as a potent and prevalent risk factor for accelerated atherosclerosis and ischemic heart disease. However, there is also evidence of cardiac dysfunction in diabetes in the absence of coronary atherosclerosis, termed diabetic cardiomyopathy. Changes in ventricular structure and left...

journal_title：Current hypertension reports

authors： Karnik AA,Fields AV,Shannon RP

更新日期：2007-12-01 00:00:00

abstract：:The renal pressure-natriuresis mechanism is the dominant controller of body fluid balance and long-term arterial pressure. In recent years, it has become clear that the balance of reactive oxygen and nitrogen species within the renal medullary region is a key determinant of the set point of the renal pressure-natriure...

journal_title：Current hypertension reports

authors： O'Connor PM,Cowley AW Jr

更新日期：2010-04-01 00:00:00

abstract：:The ubiquitin-proteasome system (UPS) is a major proteolytic system that regulates the degradation of intracellular proteins in the heart. The UPS regulates the turnover of misfolded and damaged proteins, in addition to numerous cellular processes, by affecting the stability of short-lived proteins such as transcripti...

journal_title：Current hypertension reports

authors： Rodríguez JE,Schisler JC,Patterson C,Willis MS

更新日期：2009-12-01 00:00:00

abstract：:The kidneys play a central role in the long-term regulation of blood pressure and in the pathogenesis of hypertension. A common defect that has been found in all forms of hypertension examined to date is a hypertensive shift in the pressure-natriuresis relationship. A major objective of this brief review is to highlig...

journal_title：Current hypertension reports

authors： Granger JP,Abram S,Stec D,Chandler D,LaMarca B

更新日期：2006-08-01 00:00:00

abstract：:This review is focused on the interplay between two major factors affecting the vascular tree in diabetes, insulin resistance, and hyperglycemia. The implications for vascular function, structure, and the interaction between vascular cells and other tissues by which they are affected under these conditions are reviewe...

journal_title：Current hypertension reports

authors： Stern N,Marcus Y

更新日期：2004-04-01 00:00:00

abstract：:Epinephrine is the prototypical stress hormone. Its stimulation of all α and β adrenergic receptors elicits short-term systolic hypertension, hyperglycemia, and other aspects of the metabolic syndrome. Acute epinephrine infusion increases cardiac output and induces insulin resistance, but removal of the adrenal medull...

journal_title：Current hypertension reports

authors： Ziegler MG,Elayan H,Milic M,Sun P,Gharaibeh M

更新日期：2012-02-01 00:00:00

abstract：:Hypertension is very common in patients with chronic renal failure and contributes to cardiovascular morbidity and mortality. Several mechanisms may contribute to hypertension in these patients, but recently a large body of evidence supports the notion that activation of the sympathetic nervous system (SNS) may play a...

journal_title：Current hypertension reports

authors： Campese VM,Krol E

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF THE REVIEW:In our innate immune system, neutrophils are the first cells to sense signals of infection and to proceed to kill the invading pathogen. This is mediated by their production of neutrophil extracellular traps (NETS) to entrap pathogenic micro-organisms, preventing their amplification and disseminat...

journal_title：Current hypertension reports

authors： Moodley M,Moodley J,Naicker T

更新日期：2020-05-27 00:00:00

abstract：PURPOSE OF REVIEW:To review latest reports of the food products which might increase blood pressure and therefore might participate in the pathogenesis of hypertension. RECENT FINDINGS:Results of clinical study suggest that consumption of high-sodium food leads to transient increase in plasma sodium concentration. Thi...

journal_title：Current hypertension reports

authors： Adamczak M,Wiecek A

更新日期：2020-01-08 00:00:00

abstract：:The underlying pathophysiologic concept of diverse invasive devices to treat resistant hypertension (e.g., sympathetic denervation, carotid sinus nerve stimulation) is known for a long time. Since the pioneering work in the 1940s in humans, innovative techniques have been developed resulting in less invasive treatment...

journal_title：Current hypertension reports

authors： Ott C,Schmieder RE

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To review data supporting the use of home blood pressure monitoring (HBPM) and provide practical guidance to clinicians wishing to incorporate HBPM into their practice. RECENT FINDINGS:HBPM more accurately reflects the risk of cardiovascular events than office blood pressure measurement. In addition,...

journal_title：Current hypertension reports

authors： Liyanage-Don N,Fung D,Phillips E,Kronish IM

更新日期：2019-02-12 00:00:00

abstract：:Women with chronic hypertension and pregnancy-induced hypertension are at substantial risk for developing pre-eclampsia/eclampsia, a disease with high fetomaternal morbidity and mortality. However, the etiology of this disease is still unknown. In this article, recent concepts on the pathophysiology of pre-eclampsia, ...

journal_title：Current hypertension reports

authors： Kashiwagi M,Zimmermann R,Beinder E

更新日期：2003-12-01 00:00:00

abstract：:In the quest for "evidence-based" medicine, an accepted hierarchy of evidence has been proposed. This hierarchy places in vitro studies and animal data at the base, and puts systematic reviews, meta-analyses, and randomized controlled trials at the pinnacle. However, when clinical medicine faces questions that have no...

journal_title：Current hypertension reports

authors： Hawkins RG

更新日期：2006-06-01 00:00:00

abstract：:Hypertension is the leading risk factor for the global burden of disease, yet more than 20% of adults with hypertension are unaware of their condition. Underlying hypertension affects over 25% emergency department attendees, and the condition is more commonly encountered in emergency departments than in primary care s...

journal_title：Current hypertension reports

authors： Chan SS,Graham CA,Rainer TH

更新日期：2016-04-01 00:00:00

abstract：:Investigations using chronic blood pressure (BP) radiotelemetry in conscious animals have provided substantial insights into the pathophysiology of hypertensive renal damage. Normal renal autoregulation protects the renal microvasculature from significant injury in most patients with primary hypertension, unless BP ex...

journal_title：Current hypertension reports

authors： Griffin KA,Bidani AK

更新日期：2004-04-01 00:00:00

abstract：:Resistant hypertension is defined as blood pressure that remains uncontrolled despite using at least three antihypertensive medications in effective doses, ideally including a diuretic. Stricter blood pressure goals, higher obesity rates, older age, and increased use of certain exogenous substances are related to an i...

journal_title：Current hypertension reports

authors： Pimenta E,Calhoun DA

更新日期：2007-11-01 00:00:00

abstract：:Diastolic pressure, systolic pressure, and pulse pressure have all been assigned the role of the best predictor of cardiovascular events during the 20th century. At the dawn of the new millennium, concepts that draw attention to vascular mechanics reconcile the seemingly conflicting results of epidemiologic studies, b...

journal_title：Current hypertension reports

authors： Vlachopoulos C,O'Rourke M

更新日期：2000-06-01 00:00:00