Abstract：
:Diastolic pressure, systolic pressure, and pulse pressure have all been assigned the role of the best predictor of cardiovascular events during the 20th century. At the dawn of the new millennium, concepts that draw attention to vascular mechanics reconcile the seemingly conflicting results of epidemiologic studies, better define the hypertensive patient, evaluate more accurately the risk and set its markers, and ultimately optimize treatment through a logical approach that aims at the mechanism and not at the manifestation. Pulse wave analysis and measurement of arterial stiffness are valuable tools in the assessment and management of the hypertensive patient.
journal_name
Curr Hypertens Repjournal_title
Current hypertension reportsauthors
Vlachopoulos C,O'Rourke Mdoi
10.1007/s11906-000-0010-6keywords:
subject
Has Abstractpub_date
2000-06-01 00:00:00pages
271-9issue
3eissn
1522-6417issn
1534-3111journal_volume
2pub_type
杂志文章,评审abstract：PURPOSE OF REVIEW:We focus on the current understanding of preeclampsia (PE) in order to examine how it mediates glomerular injury and affects the course of glomerulonephritis (GNs). In addition, this review discusses the role of GNs on the development of PE. RECENT FINDINGS:In PE, the dysfunctional utero-placental pe...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-020-1033-9
更新日期：2020-03-21 00:00:00
abstract：:Peak-systolic blood pressure (SBP) and end-diastolic blood pressure (DBP) have been considered the exclusive mechanical factors predicting cardiovascular (CV) risk in populations of normotensive and hypertensive subjects. The purpose of this review is to show that in addition to SBP and DBP, other hemodynamic indices ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-004-0068-7
更新日期：2004-06-01 00:00:00
abstract：:Hypertension and high serum cholesterol levels are two of the most relevant risk factors for cardiovascular diseases. A combined increase in both risk factors has been reported in a significant proportion of patients with coronary artery disease. Statins are the most widely used drugs to treat hypercholesterolemia, an...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-001-0090-y
更新日期：2001-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Use of antihypertensives in older adults can be complicated by the potential for undesired effects on comorbidities, adverse effects of the drugs, and overall medication burden. The purpose of this two-part review is to discuss contemporary issues encountered in the management of hypertension in aged ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0988-x
更新日期：2019-10-10 00:00:00
abstract：:The World Health Organization's annual report World Health Statistics 2012 was recently published. In addition to annually published indicators of health, this year's report contains a highlighted new section on non-communicable diseases and their impact on world health. The section gives particular attention to hyper...
journal_title：Current hypertension reports
pub_type： 杂志文章
doi：10.1007/s11906-012-0303-6
更新日期：2012-12-01 00:00:00
abstract：:The epithelial sodium channel (ENaC) is a membrane protein made of three different but homologous subunits (a, b, and g) present in the apical membrane of epithelial cells of, for example, the distal nephron. This channel is responsible for salt reabsorption in the kidney and can cause human diseases by increasing cha...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-003-0005-1
更新日期：2003-02-01 00:00:00
abstract：:The kidneys play a central role in the long-term regulation of blood pressure and in the pathogenesis of hypertension. A common defect that has been found in all forms of hypertension examined to date is a hypertensive shift in the pressure-natriuresis relationship. A major objective of this brief review is to highlig...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-006-0068-x
更新日期：2006-08-01 00:00:00
abstract：:High blood pressure in the setting of type 1 and type 2 diabetes is commonly associated with the earlier development of target-organ damage, including cardiovascular and cerebrovascular disease and progressive renal insufficiency. The major goal of treating high blood pressure in this population is to prevent or reduc...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-003-0020-2
更新日期：2003-06-01 00:00:00
abstract：:The concept of "perioperative hypertensive emergency" must be defined differently from that of ambulatory hypertensive emergency in view of its unique clinical considerations in an atypical setting. It should be noted that moderately high normal blood pressure (BP) values in the perioperative setting often trigger sit...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-014-0448-6
更新日期：2014-07-01 00:00:00
abstract：:Nitric oxide is involved in the regulation of resting vascular tone, adaptation of blood flow to metabolic demand of tissue, and adaptation of vessel diameter to volume of inflow, ie, flow-mediated dilation. Arterial hypertension is associated with an increased vascular tone of resistance vessels, a reduced compliance...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-003-0015-z
更新日期：2003-02-01 00:00:00
abstract：:Vascular changes associated with elevated blood pressure may precede the clinical diagnosis of hypertension. Even after the diagnosis is made, associated coronary heart disease and renal disease continue to progress, despite adequate blood pressure control. Early treatment of blood pressure may reduce the incidence of...
journal_title：Current hypertension reports
pub_type： 临床试验,杂志文章,评审
doi：10.1007/s11906-000-0038-7
更新日期：2000-08-01 00:00:00
abstract：PURPOSE OF REVIEW:This is a review of available data on the effects of blood pressure and statins on cognition. RECENT FINDINGS:Recent randomized clinical trials have shown that intensive control of systolic blood pressure in older adults prevented the development of mild cognitive impairment (MCI) and the combined ef...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0973-4
更新日期：2019-07-26 00:00:00
abstract：PURPOSE OF REVIEW:Do dietary fats lower blood pressure? This review covers total fats, individual fatty acids and foods that provide specific fats. RECENT FINDINGS:Evidence for blood pressure lowering is stronger for supplements providing individual marine fatty acids than for fish intake since data on fish consumptio...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0918-y
更新日期：2019-02-12 00:00:00
abstract：:This review attempts to highlight the potential of calcium-channel blockers in the prevention of sequelae of diabetes mellitus and hypertension in patients who have both disorders. Evidence-based medicine is driven by the results of randomized, clinical trials. Major contributions were therefore derived from post hoc ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-999-0025-6
更新日期：1999-06-01 00:00:00
abstract：:The nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling system is a well-characterized modulator of cardiovascular function, in general, and blood pressure, in particular. The availability of mice mutant for key enzymes in the NO-cGMP signaling system facilitated the identification of interactions with o...
journal_title：Current hypertension reports
pub_type： 杂志文章
doi：10.1007/s11906-012-0320-5
更新日期：2013-02-01 00:00:00
abstract：PURPOSE OF REVIEW:The overactive renin-angiotensin-aldosterone system (RAAS) plays an important part in many pathologic conditions including hypertension, heart failure, and renal disease. Hyperkalemia, a potentially life-threatening side effect of RAAS inhibitors, limits their use. The recent introduction of new hyper...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-016-0663-4
更新日期：2016-07-01 00:00:00
abstract：:Primary aldosteronism is commonly regarded as largely sporadic, but both germline and somatic mutations are increasingly recognized as underlying the condition. Three germline mutations causing familial hyperaldosteronism have been described, dubbed FH I (due to a CYP11B1/CYP11B2 chimera), FH II (localized to chromoso...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-012-0255-x
更新日期：2012-04-01 00:00:00
abstract：:Inflammation plays an important role in the pathogenesis of hypertension. Innate and adaptive immune response may contribute to this process. The mechanisms implicating immune response in hypertension are still elusive. To date, the evidence originates in three major areas of data: cytokine production, central nervous...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-011-0224-9
更新日期：2011-12-01 00:00:00
abstract：PURPOSE OF THE REVIEW:It is well-established that the age-related increase in blood pressure is augmented after menopause. Yet, the prevalence of hypertension is enhanced in low birth weight women relative to normal birth weight counterparts by 60 years of age suggesting that adverse influences during fetal life height...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-017-0712-7
更新日期：2017-02-01 00:00:00
abstract：:The fact that cardiovascular risk factors cluster among individuals with the insulin resistance syndrome strongly suggests a common pathogenetic denominator. For many years, abnormalities of nonesterified fatty acid metabolism have been implicated in the disturbances of carbohydrate and lipid metabolism that character...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-001-0021-y
更新日期：2001-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Automated office blood pressure (AOBP) measurements may provide more accurate estimation of blood pressure (BP) than manual office blood pressure (MOBP) measurements. This systematic review investigated the diagnostic performance of AOBP and MOBP using ambulatory blood pressure measurement (ABPM) as r...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-020-01118-1
更新日期：2021-01-15 00:00:00
abstract：:Aldosterone antagonists have been highly successful in treating congestive heart failure and resistant hypertension. Until recently, therapies targeting the mineralocorticoid receptor in chronic kidney disease (CKD) have received little attention, largely because of the risk of hyperkalemia and the incorrect assumptio...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-011-0202-2
更新日期：2011-08-01 00:00:00
abstract：:Over the last few decades, there has been increasing emphasis on cardiovascular disease in women and study of female-specific cardiovascular risk factors. Hypertension in pregnancy, and specifically preeclampsia, has been identified as one such risk factor. In this review, we explore the epidemiological evidence for p...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-014-0472-6
更新日期：2014-09-01 00:00:00
abstract：PURPOSE OF REVIEW:To review data supporting the use of home blood pressure monitoring (HBPM) and provide practical guidance to clinicians wishing to incorporate HBPM into their practice. RECENT FINDINGS:HBPM more accurately reflects the risk of cardiovascular events than office blood pressure measurement. In addition,...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0916-0
更新日期：2019-02-12 00:00:00
abstract：:Nycthemeral changes in renal function have been known for a long time, but our knowledge about the underlying mechanisms is still far from complete. From a theoretical point of view, many physiological systems could be involved in turning the kidney from a sodium-excretory organ during daytime into a sodium-conserving...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-011-0183-1
更新日期：2011-04-01 00:00:00
abstract：PURPOSE OF REVIEW:This review provides a comprehensive insight into the angiogenic profile of hypertensive and normotensive pregnancies compromised by HIV infection. Furthermore, we evaluate the economic implementation of the sFlt-1/PlGF ratio and review the reports on therapeutic apheresis in limiting sFlt-1 productio...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0970-7
更新日期：2019-07-24 00:00:00
abstract：:Renal sympathetic efferent and afferent nerves, which lie within and immediately adjacent to the wall of the renal arteries, contribute to the maintenance of hypertension. Because the causative factors of hypertension change over time, denervation of both efferent and afferent renal nerves should result in long-term a...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-010-0108-4
更新日期：2010-06-01 00:00:00
abstract：:The obesity gene product leptin plays an important role in the physiologic regulation of appetite and energy balance. Plasma leptin levels correlate closely with body fat storage and may respond to changes in energy expenditure. Recent evidence has implicated a direct cardiac regulatory action of leptin in addition to...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-008-0084-0
更新日期：2008-12-01 00:00:00
abstract：:Essential hypertension is characterized by endothelial dysfunction due to reduced availability of nitric oxide (NO) secondary to increased generation of oxygen-free radicals. Some antihypertensive drugs may improve or restore endothelial function independently of their blood pressure lowering effect. The newer generat...
journal_title：Current hypertension reports
pub_type： 杂志文章
doi：10.1007/s11906-011-0207-x
更新日期：2011-08-01 00:00:00
abstract：PURPOSE OF REVIEW:To review latest reports of the food products which might increase blood pressure and therefore might participate in the pathogenesis of hypertension. RECENT FINDINGS:Results of clinical study suggest that consumption of high-sodium food leads to transient increase in plasma sodium concentration. Thi...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-1007-y
更新日期：2020-01-08 00:00:00
