Abstract：
PURPOSE OF REVIEW:Hypertension remains to be a major contributor to global morbidity and mortality. Despite a plethora of pharmacological options available, an abundance of patients have uncontrolled blood pressure thus creating the need for additional strategies, including non-pharmacologic approaches. In this review, we discuss the antihypertensive effect of slow and deep respiration by increasing baroreflex sensitivity. RECENT FINDINGS:Asking patients to carry out paced breathing sessions unaccompanied by a personal coach or unaided by a device may be unfeasible. Among proposed breathing techniques, RESPeRATE is a US Food and Drug Administration-certified device that assists slow breathing. In this review, we consider the mechanisms through which guided breathing mechanisms may impact on blood pressure control and alternative techniques. Guided breathing techniques along with lifestyle therapies may be helpful as a first step for patients with mild hypertension and prehypertension who do not suffer from cardiovascular disease, renal disease, or diabetes. Drug therapy must be considered after a couple of months if non-pharmacological therapy was unsuccessful. Device-guided paced breathing (DGB) may be recommended for those who cannot obtain full control of their hypertension with medical therapy alone or cannot tolerate potential side effects of pharmacologic treatment. Also, patients with well-controlled hypertension who may wish to try to reduce medication burden may be candidates for DGB. Patients with white coat or labile hypertension who are interested in biofeedback techniques could also be considered.
journal_name
Curr Hypertens Repjournal_title
Current hypertension reportsauthors
Cernes R,Zimlichman Rdoi
10.1007/s11906-017-0742-1subject
Has Abstractpub_date
2017-06-01 00:00:00pages
45issue
6eissn
1522-6417issn
1534-3111pii
10.1007/s11906-017-0742-1journal_volume
19pub_type
杂志文章,评审abstract：PURPOSE OF REVIEW:To review the current literature on use of telehealth at different stages of the hypertension control cascade in sub-Saharan Africa (SSA) and to discuss opportunities to harness technology infrastructure in SSA to improve population-level blood pressure control. RECENT FINDINGS:Despite the high burde...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0983-2
更新日期：2019-08-26 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-014-0512-2
更新日期：2015-02-01 00:00:00
abstract：:The research on molecular genetics of human hypertension aims to identify the loci involved in the regulation of blood pressure, detect gene variants within the identified loci, associate them with intermediate phenotypes, and ultimately estimate their quantitative effects on blood pressure level and their interaction...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-999-0071-0
更新日期：1999-02-01 00:00:00
abstract：:Hypertension is a preventable condition, and the outcomes of clinical trials have established that its treatment reduces cardiovascular morbidity and mortality. Although awareness about the disease has improved in the past two decades, the reality is that many people remain untreated or not adequately controlled. The ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-001-0007-9
更新日期：2001-12-01 00:00:00
abstract：:Insulin resistance (IR) is present in pathologies such as diabetes, obesity, metabolic syndrome, impaired glucose tolerance, hypertension, inflammation, cardiac disease, and dyslipidemias. Population studies show that IR is multifactorial and has genetic components, such as defects in the insulin-signaling pathway (as...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-015-0615-4
更新日期：2016-01-01 00:00:00
abstract：:Hypertension contributes greatly to global disease burden and in many patients current treatments do not adequately control blood pressure (BP). Endothelin-1 (ET-1) is a potent vasoconstrictor that is implicated in the pathogenesis of hypertension, including the hypertension that is often associated with chronic kidne...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-013-0380-1
更新日期：2013-10-01 00:00:00
abstract：:The metabolic syndrome associates metabolic abnormalities such as insulin resistance and dyslipidemia with increased waist circumference and hypertension. It is a major public health concern, as its prevalence could soon reach 30% to 50% in developed countries. Aldosterone, a mineralocorticoid hormone classically invo...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-011-0182-2
更新日期：2011-04-01 00:00:00
abstract：PURPOSE OF REVIEW:The overactive renin-angiotensin-aldosterone system (RAAS) plays an important part in many pathologic conditions including hypertension, heart failure, and renal disease. Hyperkalemia, a potentially life-threatening side effect of RAAS inhibitors, limits their use. The recent introduction of new hyper...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-016-0663-4
更新日期：2016-07-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-003-0030-0
更新日期：2003-06-01 00:00:00
abstract：:Na+,K+-ATPase distributes ions between the intracellular and extracellular space and is responsible for total-body sodium homeostasis. The activity of this ion pump is regulated by catecholamines and peptide hormones; by the ligand of Na+,K+-ATPase, ouabain; and by direct interaction with cytoskeleton proteins. This r...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-001-0032-8
更新日期：2001-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Review the renal nerve anatomy and physiology basics and explore the concept of global vs. selective renal denervation (RDN) to uncover some of the fundamental limitations of non-targeted renal nerve ablation and the potential superiority of selective RDN. RECENT FINDINGS:Recent trials testing the ef...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-018-0838-2
更新日期：2018-05-01 00:00:00
abstract：:Diabetes mellitus is well recognized as a potent and prevalent risk factor for accelerated atherosclerosis and ischemic heart disease. However, there is also evidence of cardiac dysfunction in diabetes in the absence of coronary atherosclerosis, termed diabetic cardiomyopathy. Changes in ventricular structure and left...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-007-0086-3
更新日期：2007-12-01 00:00:00
abstract：:Cardiovascular disease is the leading cause of death in women and claims the lives of more than half a million women every year. Hypertension is one of the most prevalent and powerful contributors to atherosclerotic cardiovascular disease. Hypertension affects more men than women until 55 years of age, but after age 5...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-000-0083-2
更新日期：2000-04-01 00:00:00
abstract：:Angiotensin II is the most active hormone of the renin-angiotensin system. In humans, two angiotensin receptors have been identified: AT(1) and AT(2). In adults, most of the effects of angiotensin II are mediated by the AT(1) receptor; the function of the AT(2) receptor is not yet well established. Angiotensin II has ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-999-0036-3
更新日期：1999-08-01 00:00:00
abstract：PURPOSE OF REVIEW:This is a review of available data on the effects of blood pressure and statins on cognition. RECENT FINDINGS:Recent randomized clinical trials have shown that intensive control of systolic blood pressure in older adults prevented the development of mild cognitive impairment (MCI) and the combined ef...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0973-4
更新日期：2019-07-26 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-010-0108-4
更新日期：2010-06-01 00:00:00
abstract：:Interpretation of some recent trials in hypertension opened a debate on the clinical value of new-onset diabetes in treated hypertensive patients. It is not completely clear whether certain antihypertensive drug classes are associated with a higher risk for developing type 2 diabetes when compared with other classes. ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-005-0006-3
更新日期：2005-06-01 00:00:00
abstract：:The obesity gene product leptin plays an important role in the physiologic regulation of appetite and energy balance. Plasma leptin levels correlate closely with body fat storage and may respond to changes in energy expenditure. Recent evidence has implicated a direct cardiac regulatory action of leptin in addition to...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-008-0084-0
更新日期：2008-12-01 00:00:00
abstract：:Primary aldosteronism is commonly regarded as largely sporadic, but both germline and somatic mutations are increasingly recognized as underlying the condition. Three germline mutations causing familial hyperaldosteronism have been described, dubbed FH I (due to a CYP11B1/CYP11B2 chimera), FH II (localized to chromoso...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-012-0255-x
更新日期：2012-04-01 00:00:00
abstract：:Albuminuria is an early marker for diabetic nephropathy in patients with diabetes, and has a clear place in patient care. It also predicts cardiovascular events and mortality in diabetic patients and in the general population, and is slowly becoming accepted in population screening for cardiovascular disease and chron...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-009-0021-x
更新日期：2009-04-01 00:00:00
abstract：:Hypertension and high serum cholesterol levels are two of the most relevant risk factors for cardiovascular diseases. A combined increase in both risk factors has been reported in a significant proportion of patients with coronary artery disease. Statins are the most widely used drugs to treat hypercholesterolemia, an...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-001-0090-y
更新日期：2001-08-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章
doi：10.1007/s11906-018-0886-7
更新日期：2018-08-07 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-017-0763-9
更新日期：2017-08-01 00:00:00
abstract：:Peak-systolic blood pressure (SBP) and end-diastolic blood pressure (DBP) have been considered the exclusive mechanical factors predicting cardiovascular (CV) risk in populations of normotensive and hypertensive subjects. The purpose of this review is to show that in addition to SBP and DBP, other hemodynamic indices ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-004-0068-7
更新日期：2004-06-01 00:00:00
abstract：PURPOSE OF REVIEW:The purpose of this meta-analysis was to compare the magnitude of systematic bias (mean difference) and random error (standard deviation of mean difference) between the cuff method of indirect blood pressure and directly measured intra-arterial pressure. RECENT FINDINGS:Blood pressure is almost exclu...
journal_title：Current hypertension reports
pub_type： 杂志文章,meta分析
doi：10.1007/s11906-019-0929-8
更新日期：2019-02-07 00:00:00
abstract：:The underlying pathophysiologic concept of diverse invasive devices to treat resistant hypertension (e.g., sympathetic denervation, carotid sinus nerve stimulation) is known for a long time. Since the pioneering work in the 1940s in humans, innovative techniques have been developed resulting in less invasive treatment...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-014-0488-y
更新日期：2014-11-01 00:00:00
abstract：PURPOSE OF REVIEW:The renin-angiotensin system (RAS) plays an important role in modulating cardiovascular function and fluid homeostasis. While the systemic actions of the RAS are widely accepted, the role of the RAS in the brain, its regulation of cardiovascular function, and sympathetic outflow remain controversial. ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-018-0810-1
更新日期：2018-02-26 00:00:00
abstract：PURPOSE OF REVIEW:This review summarizes the most recent and innovative implementation strategies for hypertension control in low- and middle-income countries (LMICs). RECENT FINDINGS:Implementation strategies from Latin America, Africa, and Asia were organized across three levels: community, health system, and policy...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-020-01045-1
更新日期：2020-05-13 00:00:00
abstract：PURPOSE OF REVIEW:To evaluate recent developments in the management of hypertension in obese pregnant women. RECENT FINDINGS:The mainstay of management targets prevention of hypertension with preconception counselling, entering pregnancy with a lower BMI, limiting weight gain, and taking low-dose aspirin to prevent pr...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0927-x
更新日期：2019-03-26 00:00:00
abstract：:The renin-angiotensin system (RAS) plays an important role in the initiation and progression of tissue injuries in the cardiovascular and nervous systems. The detrimental actions of the AT1 receptor (AT1R) in hypertension and vascular injury, myocardial infarction and brain ischemia are well established. In the past t...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-013-0416-6
更新日期：2014-02-01 00:00:00
