Renal Nerve Stimulation as Procedural End Point for Renal Sympathetic Denervation.

abstract：:In the quest for "evidence-based" medicine, an accepted hierarchy of evidence has been proposed. This hierarchy places in vitro studies and animal data at the base, and puts systematic reviews, meta-analyses, and randomized controlled trials at the pinnacle. However, when clinical medicine faces questions that have no...

journal_title：Current hypertension reports

authors： Hawkins RG

更新日期：2006-06-01 00:00:00

abstract：:Hypertension is the leading risk factor for the global burden of disease, yet more than 20% of adults with hypertension are unaware of their condition. Underlying hypertension affects over 25% emergency department attendees, and the condition is more commonly encountered in emergency departments than in primary care s...

journal_title：Current hypertension reports

authors： Chan SS,Graham CA,Rainer TH

更新日期：2016-04-01 00:00:00

abstract：:The nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling system is a well-characterized modulator of cardiovascular function, in general, and blood pressure, in particular. The availability of mice mutant for key enzymes in the NO-cGMP signaling system facilitated the identification of interactions with o...

journal_title：Current hypertension reports

authors： Thoonen R,Sips PY,Bloch KD,Buys ES

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To estimate the impact of the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines for high blood pressure (BP) on the next hypertension guidelines in Asia. RECENT FINDINGS:The 2017 ACC/AHA guidelines for high BP in adults changed the diagnostic threshold and the manage...

journal_title：Current hypertension reports

authors： Nakagawa N,Hasebe N

更新日期：2019-01-10 00:00:00

abstract：PURPOSE OF REVIEW:This review sought to evaluate the role of exercise in patients with obesity and comorbid hypertension, with a focus on contemporary literature (since January 2015). RECENT FINDINGS:No reviews have included patients classified with both obesity and hypertension and there is a paucity of randomised co...

journal_title：Current hypertension reports

authors： Keating SE,Coombes JS,Stowasser M,Bailey TG

更新日期：2020-09-03 00:00:00

abstract：:The impaired capacity of the kidney to excrete sodium plays an essential role in the development of hypertension. Adrenal corticosteroids control renal handling of sodium by regulating tubular sodium reabsorption in the distal nephron where both mineralocorticoid receptors (MR) and glucocorticoid receptors are express...

journal_title：Current hypertension reports

authors： Ayuzawa N,Fujita T

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer's disease; however, associations between antihypertensive medications (AHMs) and dementia risk are less consistent. An increased interest in AHM has resulted in ex...

journal_title：Current hypertension reports

authors： Yasar S,Schuchman M,Peters J,Anstey KJ,Carlson MC,Peters R

更新日期：2016-08-01 00:00:00

abstract：:Prorenin and renin bind to a 350-amino acid protein called the (pro)renin receptor, which is present on the surface and functions intracellularly. When the receptor's N terminus binds either prorenin or renin, intracellular signaling occurs via extracellular-regulated kinases, which can result in plasminogen activator...

journal_title：Current hypertension reports

authors： Müller DN,Luft FC

更新日期：2008-10-01 00:00:00

abstract：:Nycthemeral changes in renal function have been known for a long time, but our knowledge about the underlying mechanisms is still far from complete. From a theoretical point of view, many physiological systems could be involved in turning the kidney from a sodium-excretory organ during daytime into a sodium-conserving...

journal_title：Current hypertension reports

authors： de Leeuw PW

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to systematically review existing evidence on the effectiveness of mobile health technology (mHealth) interventions in addressing medication adherence among people with hypertension. RECENT FINDINGS:Twenty-one studies of mHealth interventions were included in the final review after sy...

journal_title：Current hypertension reports

authors： Xiong S,Berkhouse H,Schooler M,Pu W,Sun A,Gong E,Yan LL

更新日期：2018-08-07 00:00:00

abstract：:The publication of the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, when used in conjunction with a new meta-analysis, provides hypertension research with a watershed. Data demonstrate clearly that lowering blood pressure is the most important aspect of hypertension man...

journal_title：Current hypertension reports

authors： Wang JG,Staessen JA,Heagerty AM

更新日期：2003-08-01 00:00:00

abstract：:Hypertension is a major cause of morbidity and mortality worldwide. Despite a myriad of oral agents, many patients fail to reach their target blood pressure. Electrical stimulation of the carotid sinus, an old therapeutic concept, lowers blood pressure by initiating the baroreflex and reducing sympathetic tone. Recent...

journal_title：Current hypertension reports

authors： Filippone JD,Sloand JA,Illig KA,Bisognano JD

更新日期：2006-10-01 00:00:00

abstract：:The fact that cardiovascular risk factors cluster among individuals with the insulin resistance syndrome strongly suggests a common pathogenetic denominator. For many years, abnormalities of nonesterified fatty acid metabolism have been implicated in the disturbances of carbohydrate and lipid metabolism that character...

journal_title：Current hypertension reports

authors： Egan BM,Greene EL,Goodfriend TL

更新日期：2001-04-01 00:00:00

abstract：:Diabetes mellitus is well recognized as a potent and prevalent risk factor for accelerated atherosclerosis and ischemic heart disease. However, there is also evidence of cardiac dysfunction in diabetes in the absence of coronary atherosclerosis, termed diabetic cardiomyopathy. Changes in ventricular structure and left...

journal_title：Current hypertension reports

authors： Karnik AA,Fields AV,Shannon RP

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This is a review of available data on the effects of blood pressure and statins on cognition. RECENT FINDINGS:Recent randomized clinical trials have shown that intensive control of systolic blood pressure in older adults prevented the development of mild cognitive impairment (MCI) and the combined ef...

journal_title：Current hypertension reports

authors： Yang M,Williamson J

更新日期：2019-07-26 00:00:00

abstract：:Salt-sensitive hypertension is closely related with natriuretic capacity of the kidney. Besides several genome-wide research reported candidate gene or gene polymorphism responsible for salt-sensitive hypertension, recently, several new factors for acquired salt-sensitive hypertension are reported. Among them, we have...

journal_title：Current hypertension reports

authors： Shimosawa T,Mu S,Shibata S,Fujita T

更新日期：2012-10-01 00:00:00

abstract：:Excess weight gain is a major cause of essential hypertension, and abnormal kidney function appears to be a cause as well as a consequence of obesity hypertension. Excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role in mediating increased blood pressure associated with w...

journal_title：Current hypertension reports

authors： Hall JE

更新日期：2000-04-01 00:00:00

abstract：:Individuals with hypertension need to stay on therapy with antihypertensive medication to obtain the full benefits of blood pressure reduction. There are important differences in tolerability across antihypertensive drug classes, and these differences influence the extent to which patients are willing to continue taki...

journal_title：Current hypertension reports

authors： Gerth WC

更新日期：2002-12-01 00:00:00

abstract：:When a large multicenter research trial is abruptly terminated, it is usually a consequence of significant adverse events. In contrast, when the Randomized Aldactone Evaluation Study (RALES) mortality trial was discontinued 18 months early, it was because of the prominent salutary effect of spironolactone, added to st...

journal_title：Current hypertension reports

authors： Soberman JE,Weber KT

更新日期：2000-10-01 00:00:00

abstract：PURPOSE OF REVIEW:In chronic kidney disease (CKD), plasma uric acid levels are increased because of the decrease in glomerular filtration rate. However, in addition to CKD, hyperuricemia is frequently associated with a number of other conditions such as hypertension, type 2 diabetes, obesity, and heart failure, overwei...

journal_title：Current hypertension reports

authors： Kielstein JT,Pontremoli R,Burnier M

更新日期：2020-10-31 00:00:00

abstract：PURPOSE OF REVIEW:The major health issue of being overweight or obese relates to the development of hypertension, insulin resistance and diabetic complications. One of the major underlying factors influencing the elevated blood pressure in obesity is increased activity of the sympathetic nerves to particular organs suc...

journal_title：Current hypertension reports

authors： Lim K,Jackson KL,Sata Y,Head GA

更新日期：2017-07-01 00:00:00

abstract：:Current national guidelines recommend aggressive lowering of blood pressure (< 130/80 mm Hg) in patients with chronic kidney disease (CKD). In this paper, we summarize recent clinical trial data evaluating the effect of lower blood pressure goals on renal outcomes. The epidemiologic data relating blood pressure to pro...

journal_title：Current hypertension reports

authors： Rahman M,El-Meanawy A,Romanello J

更新日期：2005-10-01 00:00:00

abstract：:Blood pressure is typically lower in premenopausal women than in men. However, after menopause, the prevalence of hypertension in women is higher than it is in men. Hypertension is a major risk factor for cardiovascular disease in women and men, but cardiovascular disease is the leading cause of death in women. Furthe...

journal_title：Current hypertension reports

authors： Lima R,Wofford M,Reckelhoff JF

更新日期：2012-06-01 00:00:00

abstract：:Essential hypertension is a very common health condition that is associated with an array of long-term end-organ diseases, including premature cardiovascular disease. Currently, there is no effective method to identify high-risk patients who may develop cardiovascular comorbidities in the future. Clinically, it would ...

journal_title：Current hypertension reports

authors： Xue Y,Iqbal N,Chan J,Maisel A

更新日期：2014-12-01 00:00:00

abstract：:Women with chronic hypertension and pregnancy-induced hypertension are at substantial risk for developing pre-eclampsia/eclampsia, a disease with high fetomaternal morbidity and mortality. However, the etiology of this disease is still unknown. In this article, recent concepts on the pathophysiology of pre-eclampsia, ...

journal_title：Current hypertension reports

authors： Kashiwagi M,Zimmermann R,Beinder E

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review data supporting the use of home blood pressure monitoring (HBPM) and provide practical guidance to clinicians wishing to incorporate HBPM into their practice. RECENT FINDINGS:HBPM more accurately reflects the risk of cardiovascular events than office blood pressure measurement. In addition,...

journal_title：Current hypertension reports

authors： Liyanage-Don N,Fung D,Phillips E,Kronish IM

更新日期：2019-02-12 00:00:00

abstract：:Cardiovascular disease is the leading cause of death in women and claims the lives of more than half a million women every year. Hypertension is one of the most prevalent and powerful contributors to atherosclerotic cardiovascular disease. Hypertension affects more men than women until 55 years of age, but after age 5...

journal_title：Current hypertension reports

authors： Harrison-Bernard LM,Raij L

更新日期：2000-04-01 00:00:00

abstract：:The metabolic syndrome associates metabolic abnormalities such as insulin resistance and dyslipidemia with increased waist circumference and hypertension. It is a major public health concern, as its prevalence could soon reach 30% to 50% in developed countries. Aldosterone, a mineralocorticoid hormone classically invo...

journal_title：Current hypertension reports

authors： Briet M,Schiffrin EL

更新日期：2011-04-01 00:00:00

abstract：:Interpretation of some recent trials in hypertension opened a debate on the clinical value of new-onset diabetes in treated hypertensive patients. It is not completely clear whether certain antihypertensive drug classes are associated with a higher risk for developing type 2 diabetes when compared with other classes. ...

journal_title：Current hypertension reports

authors： Verdecchia P,Angeli F,Reboldi GP,Gattobigio R

更新日期：2005-06-01 00:00:00

abstract：:To further understand chronic heart disease, such as heart failure and cardiomyopathy, we must fully define signaling pathways within the myocardium. Recent studies suggest that some forms of heart disease are associated with a chronic low-grade inflammation that promotes adverse ventricular remodeling and correlates ...

journal_title：Current hypertension reports

authors： Ahn J,Kim J

更新日期：2012-12-01 00:00:00