Author Correction: SREBP1 drives keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer.

abstract：:Lungs resected for adenocarcinomas often harbour minute discrete foci of cytologically atypical pneumocyte proliferations designated as atypical adenomatous hyperplasia (AAH). Evidence suggests that AAH represents an initial step in the progression to adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MI...

journal_title：Nature communications

authors： Izumchenko E,Chang X,Brait M,Fertig E,Kagohara LT,Bedi A,Marchionni L,Agrawal N,Ravi R,Jones S,Hoque MO,Westra WH,Sidransky D

更新日期：2015-09-16 00:00:00

abstract：:The amniote middle ear is a classical example of the evolutionary novelty. Although paleontological evidence supports the view that mammals and diapsids (modern reptiles and birds) independently acquired the middle ear after divergence from their common ancestor, the developmental bases of these transformations remain...

journal_title：Nature communications

authors： Kitazawa T,Takechi M,Hirasawa T,Adachi N,Narboux-Nême N,Kume H,Maeda K,Hirai T,Miyagawa-Tomita S,Kurihara Y,Hitomi J,Levi G,Kuratani S,Kurihara H

更新日期：2015-04-22 00:00:00

abstract：:Quantum states induced by single-atomic impurities are at the frontier of physics and material science. While such states have been reported in high-temperature superconductors and dilute magnetic semiconductors, they are unexplored in topological magnets which can feature spin-orbit tunability. Here we use spin-polar...

journal_title：Nature communications

authors： Yin JX,Shumiya N,Jiang Y,Zhou H,Macam G,Sura HOM,Zhang SS,Cheng ZJ,Guguchia Z,Li Y,Wang Q,Litskevich M,Belopolski I,Yang XP,Cochran TA,Chang G,Zhang Q,Huang ZQ,Chuang FC,Lin H,Lei H,Andersen BM,Wang Z,Jia S

更新日期：2020-09-04 00:00:00

abstract：:Leaves lose approximately 400 H2O molecules for every 1 CO2 gained during photosynthesis. Most long-distance water transport in plants, or xylem sap flow, serves to replace this water to prevent desiccation. Theory predicts that the largest vessels contribute disproportionately to overall sap flow because flow in pipe...

journal_title：Nature communications

authors： Bouda M,Windt CW,McElrone AJ,Brodersen CR

更新日期：2019-12-10 00:00:00

abstract：:Photosynthesis is nature's route to convert intermittent solar irradiation into storable energy, while its use for an industrial energy supply is impaired by low efficiency. Artificial photosynthesis provides a promising alternative for efficient robust carbon-neutral renewable energy generation. The approach of direc...

journal_title：Nature communications

authors： May MM,Lewerenz HJ,Lackner D,Dimroth F,Hannappel T

更新日期：2015-09-15 00:00:00

abstract：:Target-centric drug development strategies prioritize single-target potency in vitro and do not account for connectivity and multi-target effects within a signal transduction network. Here, we present a systems biology approach that combines transcriptomic and structural analyses with live-cell imaging to predict smal...

journal_title：Nature communications

authors： Pabon NA,Zhang Q,Cruz JA,Schipper DL,Camacho CJ,Lee REC

更新日期：2019-02-26 00:00:00

abstract：:Chronic bacterial infections on medical devices, including catheter-associated urinary tract infections (CAUTI), are associated with bacterial biofilm communities that are refractory to antibiotic therapy and resistant to host immunity. Previously, we have shown that Pseudomonas aeruginosa can cause CAUTI by forming a...

journal_title：Nature communications

authors： Cole SJ,Hall CL,Schniederberend M,Farrow Iii JM,Goodson JR,Pesci EC,Kazmierczak BI,Lee VT

更新日期：2018-10-25 00:00:00

abstract：:The interface between LaAlO(3) and SrTiO(3) possesses a range of intriguing properties, notably a proposed connection between the surface state of the LaAlO(3) and the conductivity buried in the SrTiO(3). Here we study the effect of the surface adsorption of a variety of common laboratory solvents on the conductivity ...

journal_title：Nature communications

authors： Xie Y,Hikita Y,Bell C,Hwang HY

更新日期：2011-10-11 00:00:00

abstract：:Energy circulation in geospace lies at the heart of space weather research. In the inner magnetosphere, the steep plasmapause boundary separates the cold dense plasmasphere, which corotates with the planet, from the hot ring current/plasma sheet outside. Theoretical studies suggested that plasmapause surface waves rel...

journal_title：Nature communications

authors： He F,Guo RL,Dunn WR,Yao ZH,Zhang HS,Hao YX,Shi QQ,Rong ZJ,Liu J,Tian AM,Zhang XX,Wei Y,Zhang YL,Zong QG,Pu ZY,Wan WX

更新日期：2020-04-03 00:00:00

abstract：:Non-symmorphic chiral topological crystals host exotic multifold fermions, and their associated Fermi arcs helically wrap around and expand throughout the Brillouin zone between the high-symmetry center and surface-corner momenta. However, Fermi-arc splitting and realization of the theoretically proposed maximal Chern...

journal_title：Nature communications

authors： Yao M,Manna K,Yang Q,Fedorov A,Voroshnin V,Valentin Schwarze B,Hornung J,Chattopadhyay S,Sun Z,Guin SN,Wosnitza J,Borrmann H,Shekhar C,Kumar N,Fink J,Sun Y,Felser C

更新日期：2020-04-27 00:00:00

abstract：:Clostridium difficile is the leading cause of nosocomial diarrhea and colitis in the industrialized world. Disruption of the protective gut microbiota by antibiotics enables colonization by multidrug-resistant C. difficile, which secrete up to three different protein toxins that are responsible for the gastrointestina...

journal_title：Nature communications

authors： Tam J,Hamza T,Ma B,Chen K,Beilhartz GL,Ravel J,Feng H,Melnyk RA

更新日期：2018-12-07 00:00:00

abstract：:In-plane anisotropic ground states are ubiquitous in correlated solids such as pnictides, cuprates and manganites. They can arise from doping Mott insulators and compete with phases such as superconductivity; however, their origins are debated. Strong coupling between lattice, charge, orbital and spin degrees of freed...

journal_title：Nature communications

authors： Miller TA,Chhajlany RW,Tagliacozzo L,Green B,Kovalev S,Prabhakaran D,Lewenstein M,Gensch M,Wall S

更新日期：2015-09-18 00:00:00

abstract：:Telomerase elongates the telomeric G-strand to prevent telomere shortening through conventional DNA replication. However, synthesis of the complementary C-strand by DNA polymerase α is also required to maintain telomere length. Polymerase α cannot perform this role without the ssDNA binding complex CST (CTC1-STN1-TEN1...

journal_title：Nature communications

authors： Feng X,Hsu SJ,Bhattacharjee A,Wang Y,Diao J,Price CM

更新日期：2018-07-19 00:00:00

abstract：:Amino-terminal acetylation is among the most ubiquitous of protein modifications in eukaryotes. Although loss of N-terminal acetylation is associated with many abnormalities, the molecular basis of these effects is known for only a few cases, where acetylation of single factors has been linked to binding avidity or me...

journal_title：Nature communications

authors： Holmes WM,Mannakee BK,Gutenkunst RN,Serio TR

更新日期：2014-07-15 00:00:00

abstract：:Somatic mutations in the RNase IIIb domain of DICER1 arise in cancer and disrupt the cleavage of 5' pre-miRNA arms. Here, we characterize an unstudied, recurrent, mutation (S1344L) in the DICER1 RNase IIIa domain in tumors from The Cancer Genome Atlas (TCGA) project and MSK-IMPACT profiling. RNase IIIa/b hotspots are ...

journal_title：Nature communications

authors： Vedanayagam J,Chatila WK,Aksoy BA,Majumdar S,Skanderup AJ,Demir E,Schultz N,Sander C,Lai EC

更新日期：2019-08-15 00:00:00

abstract：:Granule cells are the dominant cell type of the olfactory bulb inhibiting mitral and tufted cells via dendrodendritic synapses; yet the factors regulating the strength of their inhibitory output, and, therefore, their impact on odour discrimination, remain unknown. Here we show that GABAAR β3-subunits are distributed ...

journal_title：Nature communications

authors： Nunes D,Kuner T

更新日期：2015-11-23 00:00:00

abstract：:Chromothripsis is a recently identified mutational phenomenon, by which a presumably single catastrophic event generates extensive genomic rearrangements of one or a few chromosome(s). Considered as an early event in tumour development, this form of genome instability plays a prominent role in tumour onset. Chromothri...

journal_title：Nature communications

authors： Voronina N,Wong JKL,Hübschmann D,Hlevnjak M,Uhrig S,Heilig CE,Horak P,Kreutzfeldt S,Mock A,Stenzinger A,Hutter B,Fröhlich M,Brors B,Jahn A,Klink B,Gieldon L,Sieverling L,Feuerbach L,Chudasama P,Beck K,Kroiss M,H

更新日期：2020-05-08 00:00:00

abstract：:Survival following a diagnosis of multiple myeloma (MM) varies between patients and some of these differences may be a consequence of inherited genetic variation. In this study, to identify genetic markers associated with MM overall survival (MM-OS), we conduct a meta-analysis of four patient series of European ancest...

journal_title：Nature communications

authors： Johnson DC,Weinhold N,Mitchell JS,Chen B,Kaiser M,Begum DB,Hillengass J,Bertsch U,Gregory WA,Cairns D,Jackson GH,Försti A,Nickel J,Hoffmann P,Nöethen MM,Stephens OW,Barlogie B,Davis FE,Hemminki K,Goldschmidt H,Hou

更新日期：2016-01-08 00:00:00

abstract：:Large-scale genetic and genomic data are increasingly available and the major bottleneck in their analysis is a lack of sufficiently scalable computational tools. To address this problem in the context of complex traits analysis, we present DISSECT. DISSECT is a new and freely available software that is able to exploi...

journal_title：Nature communications

authors： Canela-Xandri O,Law A,Gray A,Woolliams JA,Tenesa A

更新日期：2015-12-11 00:00:00

abstract：:The ice- and organic-rich permafrost of the northeast Siberian Arctic lowlands (NESAL) has been projected to remain stable beyond 2100, even under pessimistic climate warming scenarios. However, the numerical models used for these projections lack processes which induce widespread landscape change termed thermokarst, ...

journal_title：Nature communications

authors： Nitzbon J,Westermann S,Langer M,Martin LCP,Strauss J,Laboor S,Boike J

更新日期：2020-05-04 00:00:00

abstract：:Understanding how rock-forming minerals transform under shock loading is critical for modeling collisions between planetary bodies, interpreting the significance of shock features in minerals and for using them as diagnostic indicators of impact conditions, such as shock pressure. To date, our understanding of the for...

journal_title：Nature communications

authors： Gleason AE,Bolme CA,Lee HJ,Nagler B,Galtier E,Kraus RG,Sandberg R,Yang W,Langenhorst F,Mao WL

更新日期：2017-11-14 00:00:00

abstract：:The original version of this Article omitted references to previous experimental reports on solid hydrogen that are relevant for a full understanding of the context of the previous work. The added references are: 47. Akahama, Y. et al. Evidence from x-ray diffraction of orientational ordering in phase III of solid hyd...

journal_title：Nature communications

authors： Dalladay-Simpson P,Binns J,Peña-Alvarez M,Donnelly ME,Greenberg E,Prakapenka V,Chen XJ,Gregoryanz E,Howie RT

更新日期：2019-05-03 00:00:00

abstract：:Individual cells in clonal populations often respond differently to environmental changes; for binary phenotypes, such as cell death, this can be measured as a fractional response. These types of responses have been attributed to cell-intrinsic stochastic processes and variable abundances of biochemical constituents, ...

journal_title：Nature communications

authors： Santos LC,Vogel R,Chipuk JE,Birtwistle MR,Stolovitzky G,Meyer P

更新日期：2019-03-21 00:00:00

abstract：:Autophagy perturbation represents an emerging therapeutic strategy in cancer. Although LATS1 and LATS2 kinases, core components of the mammalian Hippo pathway, have been shown to exert tumor suppressive activities, here we report a pro-survival role of LATS1 but not LATS2 in hepatocellular carcinoma (HCC) cells. Speci...

journal_title：Nature communications

authors： Tang F,Gao R,Jeevan-Raj B,Wyss CB,Kalathur RKR,Piscuoglio S,Ng CKY,Hindupur SK,Nuciforo S,Dazert E,Bock T,Song S,Buechel D,Morini MF,Hergovich A,Matthias P,Lim DS,Terracciano LM,Heim MH,Hall MN,Christofori G

更新日期：2019-12-17 00:00:00

abstract：:Emerging evidence has revealed that Nestin not only serves as a biomarker for multipotent stem cells, but also regulates cell proliferation and invasion in various tumors. However, the mechanistic contributions of Nestin to cancer pathogenesis are still unknown. In the present study, previously thought to reside exclu...

journal_title：Nature communications

authors： Zhang Y,Wang J,Huang W,Cai J,Ba J,Wang Y,Ke Q,Huang Y,Liu X,Qiu Y,Lu Q,Sui X,Shi Y,Wang T,Shen H,Guan Y,Zhou Y,Chen Y,Wang M,Xiang AP

更新日期：2018-09-06 00:00:00

abstract：:MAVS and MITA are essential adaptor proteins mediating innate antiviral immune responses against RNA and DNA viruses, respectively. Here we show that RNF115 plays dual roles in response to RNA or DNA virus infections by catalyzing distinct types of ubiquitination of MAVS and MITA at different phases of viral infection...

journal_title：Nature communications

authors： Zhang ZD,Xiong TC,Yao SQ,Wei MC,Chen M,Lin D,Zhong B

更新日期：2020-11-02 00:00:00

abstract：:Quantum triangular-lattice antiferromagnets are important prototype systems to investigate numerous phenomena of the geometrical frustration in condensed matter. Apart from highly unusual magnetic properties, they possess a rich phase diagram (ranging from an unfrustrated square lattice to a quantum spin liquid), yet ...

journal_title：Nature communications

authors： Zvyagin SA,Graf D,Sakurai T,Kimura S,Nojiri H,Wosnitza J,Ohta H,Ono T,Tanaka H

更新日期：2019-03-06 00:00:00

abstract：:The direct response of the tropical mixed layer to near-inertial waves (NIWs) has only rarely been observed. Here, we present upper-ocean turbulence data that provide evidence for a strongly elevated vertical diffusive heat flux across the base of the mixed layer in the presence of a NIW, thereby cooling the mixed lay...

journal_title：Nature communications

authors： Hummels R,Dengler M,Rath W,Foltz GR,Schütte F,Fischer T,Brandt P

更新日期：2020-07-31 00:00:00

abstract：:Understanding the microscopic elementary process of chemical reactions, especially in condensed phase, is highly desirable for improvement of efficiencies in industrial chemical processes. Here we show an approach to gaining new insights into elementary reactions in condensed phase by combining quantum chemical calcul...

journal_title：Nature communications

authors： Zhang Y,Song P,Fu Q,Ruan M,Xu W

更新日期：2014-06-25 00:00:00

abstract：:The history of the Earth has been marked by major ecological transitions, driven by metabolic innovation, that radically reshaped the composition of the oceans and atmosphere. The nature and magnitude of the earliest transitions, hundreds of million years before photosynthesis evolved, remain poorly understood. Using ...

journal_title：Nature communications

authors： Sauterey B,Charnay B,Affholder A,Mazevet S,Ferrière R

更新日期：2020-06-01 00:00:00