The landscape of chromothripsis across adult cancer types.

abstract：:With the development of ultrafast electron and X-ray sources it is becoming possible to study structural dynamics with atomic-level spatial and temporal resolution. Because of their short mean free path, electrons are particularly well suited for investigating surfaces and thin films, such as the challenging and impor...

journal_title：Nature communications

authors： Engelen WJ,van der Heijden MA,Bakker DJ,Vredenbregt EJ,Luiten OJ

更新日期：2013-01-01 00:00:00

abstract：:Most tumor cells take up more glucose than normal cells. Splicing dysregulation is one of the molecular hallmarks of cancer. However, the role of splicing factor in glucose metabolism and tumor development remains poorly defined. Here, we show that upon glucose intake, the splicing factor SRSF5 is specifically induced...

journal_title：Nature communications

authors： Chen Y,Huang Q,Liu W,Zhu Q,Cui CP,Xu L,Guo X,Wang P,Liu J,Dong G,Wei W,Liu CH,Feng Z,He F,Zhang L

更新日期：2018-06-25 00:00:00

abstract：:Thanks to the nature of strong programmability, field-programmable gate arrays (FPGAs) have been playing a significant role in signal processing and control. With the explosive growth in digital data, big data analytics becomes an important emerging field, in which FPGAs are a major player. However, the computational ...

journal_title：Nature communications

authors： Zhang W,Yao J

更新日期：2020-01-21 00:00:00

abstract：:The continued convergence of electronics and photonics on the chip scale can benefit from the voltage control of optical polarization for applications in communications, signal processing and sensing. It is challenging, however, to electrically manipulate the polarization state of light in planar optical waveguides. H...

journal_title：Nature communications

authors： Xu Q,Chen L,Wood MG,Sun P,Reano RM

更新日期：2014-11-12 00:00:00

abstract：:The originally published version of this Article contained an error in the spelling of the author Md. Saiful Islam, which was incorrectly given as Saiful Islam. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Wilkins SE,Islam MS,Gannon JM,Markolovic S,Hopkinson RJ,Ge W,Schofield CJ,Chowdhury R

更新日期：2018-04-23 00:00:00

abstract：:Cognitive brain networks such as the default-mode network (DMN), frontoparietal network, and salience network, are key functional networks of the human brain. Here we show that the rapid evolutionary cortical expansion of cognitive networks in the human brain, and most pronounced the DMN, runs parallel with high expre...

journal_title：Nature communications

authors： Wei Y,de Lange SC,Scholtens LH,Watanabe K,Ardesch DJ,Jansen PR,Savage JE,Li L,Preuss TM,Rilling JK,Posthuma D,van den Heuvel MP

更新日期：2019-10-24 00:00:00

abstract：:Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs (miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However, whether miRNAs mediate osteoclast-directed osteoblastic bone formation is mostly unknown. Here, we show that increased osteoclastic miR-214-...

journal_title：Nature communications

authors： Li D,Liu J,Guo B,Liang C,Dang L,Lu C,He X,Cheung HY,Xu L,Lu C,He B,Liu B,Shaikh AB,Li F,Wang L,Yang Z,Au DW,Peng S,Zhang Z,Zhang BT,Pan X,Qian A,Shang P,Xiao L,Jiang B,Wong CK,Xu J,Bian Z,Liang Z,

更新日期：2016-03-07 00:00:00

abstract：:Protein tyrosine O-sulfation (PTS) plays a crucial role in extracellular biomolecular interactions that dictate various cellular processes. It also involves in the development of many human diseases. Regardless of recent progress, our current understanding of PTS is still in its infancy. To promote and facilitate rele...

journal_title：Nature communications

authors： He X,Chen Y,Beltran DG,Kelly M,Ma B,Lawrie J,Wang F,Dodds E,Zhang L,Guo J,Niu W

更新日期：2020-09-24 00:00:00

abstract：:The superconducting gap structure in iron-based high-temperature superconductors (Fe-HTSs) is non-universal. In contrast to other unconventional superconductors, in the Fe-HTSs both d-wave and extended s-wave pairing symmetries are close in energy. Probing the proximity between these very different superconducting sta...

journal_title：Nature communications

authors： Guguchia Z,Amato A,Kang J,Luetkens H,Biswas PK,Prando G,von Rohr F,Bukowski Z,Shengelaya A,Keller H,Morenzoni E,Fernandes RM,Khasanov R

更新日期：2015-11-09 00:00:00

abstract：:The ability to understand and control the electronic properties of individual molecules in a device environment is crucial for developing future technologies at the nanometre scale and below. Achieving this, however, requires the creation of three-terminal devices that allow single molecules to be both gated and image...

journal_title：Nature communications

authors： Wickenburg S,Lu J,Lischner J,Tsai HZ,Omrani AA,Riss A,Karrasch C,Bradley A,Jung HS,Khajeh R,Wong D,Watanabe K,Taniguchi T,Zettl A,Neto AHC,Louie SG,Crommie MF

更新日期：2016-11-25 00:00:00

abstract：:The use of graphene in electronic devices requires a band gap, which can be achieved by creating nanostructures such as graphene nanoribbons. A wide variety of atomically precise graphene nanoribbons can be prepared through on-surface synthesis, bringing the concept of graphene nanoribbon electronics closer to reality...

journal_title：Nature communications

authors： Jacobse PH,Kimouche A,Gebraad T,Ervasti MM,Thijssen JM,Liljeroth P,Swart I

更新日期：2017-07-25 00:00:00

abstract：:Nanoscale correlation of structural information acquisition with specific-molecule identification provides new insight for studying rare subcellular events. To achieve this correlation, scanning electron microscopy has been combined with super-resolution fluorescent microscopy, despite its destructivity when acquiring...

journal_title：Nature communications

authors： Wang F,Liu L,Yu H,Wen Y,Yu P,Liu Z,Wang Y,Li WJ

更新日期：2016-12-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Temko D,Tomlinson IPM,Severini S,Schuster-Böckler B,Graham TA

更新日期：2020-04-20 00:00:00

abstract：:Natural systems frequently exploit intricate multiscale and multiphasic structures to achieve functionalities beyond those of man-made systems. Although understanding the chemical make-up of these systems is essential, the passive and active mechanics within biological systems are crucial when considering the many nat...

journal_title：Nature communications

authors： Egan P,Sinko R,LeDuc PR,Keten S

更新日期：2015-07-06 00:00:00

abstract：:The low-energy electronic excitations in graphene are described by massless Dirac fermions that have a linear dispersion relation. Taking advantage of this 'optics-like' electron dynamics, generic optical elements like lenses and wave guides have been proposed for electrons in graphene. Tuning of these elements relies...

journal_title：Nature communications

authors： Rickhaus P,Maurand R,Liu MH,Weiss M,Richter K,Schönenberger C

更新日期：2013-01-01 00:00:00

abstract：:It has previously been postulated that the Earth's hydrous mantle transition zone may play a key role in intraplate magmatism, but no confirmatory evidence has been reported. Here we demonstrate that hydrothermally altered subducted oceanic crust was involved in generating the late Cenozoic Chifeng continental flood b...

journal_title：Nature communications

authors： Wang XC,Wilde SA,Li QL,Yang YN

更新日期：2015-07-14 00:00:00

abstract：:Active biofluid management is central to the realization of wearable bioanalytical platforms that are poised to autonomously provide frequent, real-time, and accurate measures of biomarkers in epidermally-retrievable biofluids (e.g., sweat). Accordingly, here, a programmable epidermal microfluidic valving system is de...

journal_title：Nature communications

authors： Lin H,Tan J,Zhu J,Lin S,Zhao Y,Yu W,Hojaiji H,Wang B,Yang S,Cheng X,Wang Z,Tang E,Yeung C,Emaminejad S

更新日期：2020-09-02 00:00:00

abstract：:Itch, in particular chronic forms, has been widely recognized as an important clinical problem, but much less is known about the mechanisms of itch in comparison with other sensory modalities such as pain. Recently, considerable progress has been made in dissecting the circuit mechanisms of itch at both the spinal and...

journal_title：Nature communications

authors： Chen XJ,Sun YG

更新日期：2020-06-16 00:00:00

abstract：:Amongst the many spectacular properties of hybrid lead halide perovskites, their defect tolerance is regarded as the key enabler for a spectrum of high-performance optoelectronic devices that propel perovskites to prominence. However, the plateauing efficiency enhancement of perovskite devices calls into question the ...

journal_title：Nature communications

authors： Righetto M,Lim SS,Giovanni D,Lim JWM,Zhang Q,Ramesh S,Tay YKE,Sum TC

更新日期：2020-06-01 00:00:00

abstract：:High-dose ionizing radiation induces severe DNA damage in the epithelial stem cells in small intestinal crypts and causes gastrointestinal syndrome (GIS). Although the tumour suppressor p53 is a primary factor inducing death of crypt cells with DNA damage, its essential role in maintaining genome stability means inhib...

journal_title：Nature communications

authors： Takemura N,Kawasaki T,Kunisawa J,Sato S,Lamichhane A,Kobiyama K,Aoshi T,Ito J,Mizuguchi K,Karuppuchamy T,Matsunaga K,Miyatake S,Mori N,Tsujimura T,Satoh T,Kumagai Y,Kawai T,Standley DM,Ishii KJ,Kiyono H,Akira S,

更新日期：2014-03-18 00:00:00

abstract：:Human-induced ocean acidification and warming alter seawater carbonate chemistry reducing the calcification of reef-building crustose coralline algae (CCA), which has implications for reef stability. However, due to the presence of multiple carbonate minerals with different solubilities in seawater, the algal mineralo...

journal_title：Nature communications

authors： Diaz-Pulido G,Nash MC,Anthony KR,Bender D,Opdyke BN,Reyes-Nivia C,Troitzsch U

更新日期：2014-01-01 00:00:00

abstract：: ...

journal_title：Nature communications

authors： Tsai D,Sawyer D,Bradd A,Yuste R,Shepard KL

更新日期：2018-10-24 00:00:00

abstract：:Proper regulation of energy storage in adipose tissue is crucial for maintaining insulin sensitivity and molecules contributing to this process have not been fully revealed. Here we show that type II transmembrane protein tenomodulin (TNMD) is upregulated in adipose tissue of insulin-resistant versus insulin-sensitive...

journal_title：Nature communications

authors： Senol-Cosar O,Flach RJ,DiStefano M,Chawla A,Nicoloro S,Straubhaar J,Hardy OT,Noh HL,Kim JK,Wabitsch M,Scherer PE,Czech MP

更新日期：2016-02-16 00:00:00

abstract：:A major challenge in environmental policymaking is determining whether and how fast our society should adopt sustainable management methods. These decisions may have long-lasting effects on the environment, and therefore, they depend critically on the discount factor, which determines the relative values given to futu...

journal_title：Nature communications

authors： Lampert A

更新日期：2019-03-29 00:00:00

abstract：:Host dependency factors that are required for influenza A virus infection may serve as therapeutic targets as the virus is less likely to bypass them under drug-mediated selection pressure. Previous attempts to identify host factors have produced largely divergent results, with few overlapping hits across different st...

journal_title：Nature communications

authors： Li B,Clohisey SM,Chia BS,Wang B,Cui A,Eisenhaure T,Schweitzer LD,Hoover P,Parkinson NJ,Nachshon A,Smith N,Regan T,Farr D,Gutmann MU,Bukhari SI,Law A,Sangesland M,Gat-Viks I,Digard P,Vasudevan S,Lingwood D,Dockre

更新日期：2020-01-09 00:00:00

abstract：:Exciton dynamics can be strongly affected by lattice vibrations through electron-phonon coupling. This is rarely explored in two-dimensional magnetic semiconductors. Focusing on bilayer CrI3, we first show the presence of strong electron-phonon coupling through temperature-dependent photoluminescence and absorption sp...

journal_title：Nature communications

authors： Jin W,Kim HH,Ye Z,Ye G,Rojas L,Luo X,Yang B,Yin F,Horng JSA,Tian S,Fu Y,Xu G,Deng H,Lei H,Tsen AW,Sun K,He R,Zhao L

更新日期：2020-09-22 00:00:00

abstract：:Generation of periodic patterns is fundamental to the differentiation of multiple tissues during development. How such patterns form robustly is still unclear. The Drosophila eye comprises ∼750 units, whose crystalline order is set during differentiation of the eye imaginal disc: an activation wave sweeping across the...

journal_title：Nature communications

authors： Gavish A,Shwartz A,Weizman A,Schejter E,Shilo BZ,Barkai N

更新日期：2016-02-15 00:00:00

abstract：:Acoustic sensors play an important role in many areas, such as homeland security, navigation, communication, health care and industry. However, the fundamental pressure detection limit hinders the performance of current acoustic sensing technologies. Here, through analytical, numerical and experimental studies, we sho...

journal_title：Nature communications

authors： Chen Y,Liu H,Reilly M,Bae H,Yu M

更新日期：2014-10-15 00:00:00

abstract：:Myopia can cause severe visual impairment. Here, we report a two-stage genome-wide association study for three myopia-related traits in 9,804 Japanese individuals, which was extended with trans-ethnic replication in 2,674 Chinese and 2,690 Caucasian individuals. We identify WNT7B as a novel susceptibility gene for axi...

journal_title：Nature communications

authors： Miyake M,Yamashiro K,Tabara Y,Suda K,Morooka S,Nakanishi H,Khor CC,Chen P,Qiao F,Nakata I,Akagi-Kurashige Y,Gotoh N,Tsujikawa A,Meguro A,Kusuhara S,Polasek O,Hayward C,Wright AF,Campbell H,Richardson AJ,Schache M

更新日期：2015-03-31 00:00:00

abstract：:Quantum Griffiths singularity was theoretically proposed to interpret the phenomenon of divergent dynamical exponent in quantum phase transitions. It has been discovered experimentally in three-dimensional (3D) magnetic metal systems and two-dimensional (2D) superconductors. But, whether this state exists in lower dim...

journal_title：Nature communications

authors： Zhang E,Zhi J,Zou YC,Ye Z,Ai L,Shi J,Huang C,Liu S,Lin Z,Zheng X,Kang N,Xu H,Wang W,He L,Zou J,Liu J,Mao Z,Xiu F

更新日期：2018-11-07 00:00:00