The effect of hyaluronic acid hydrogels on dental pulp stem cells behavior.

Abstract:

:Dental caries and trauma, particularly in childhood, are among the most prevalent teeth problems, which result in the creation of cavities and probably tooth loss. Thus, novel regenerative approaches with high efficiency and less toxicity are required. Stem cell therapy along with the implementation of scaffolds has provided excellent opportunities in the regeneration of teeth structure. Hyaluronic acid (HA) hydrogels have enticed great attention in the field of regenerative medicine. The unique chemical and structural properties of HA and its derivatives have enabled their application in tissue engineering. Several factors such as the location and type of the lesion, teeth age, the type of capping materials determine the success rate of pulp therapy. HA hydrogels have been considered as biocompatible and safe scaffold supports in human dental cell therapies.

journal_name

Int J Biol Macromol

authors

Ahmadian E,Eftekhari A,Dizaj SM,Sharifi S,Mokhtarpour M,Nasibova AN,Khalilov R,Samiei M

doi

10.1016/j.ijbiomac.2019.08.119

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

245-254

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(19)33424-5

journal_volume

140

pub_type

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