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Protective effect of polysaccharides from morinda officinalis on bone loss in ovariectomized rats.

Abstract：

:In order to examine the effect of polysaccharides from morinda officinalis (MOP) on bone quality of osteoporosis rats. The osteoporosis in rats was induced by ovariectomy, and MOP (100 or 300 mg/kg) was orally administrated once daily. The animals were assessed 30 days after the operation for bone mineral density, serum cytokines level and mineral element concentration. MOP administration in rats resulted in an increase in bone mineral density and mineral element concentration, a decrease in serum cytokines level, which indicated that MOP administration may play an important role in the development of osteoporosis.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

MengYong Z,CaiJiao W,HuSheng Z,XianWu P,JianMin F

doi

10.1016/j.ijbiomac.2008.06.008

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

276-8

issue

3

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(08)00133-5

journal_volume

43

pub_type

杂志文章

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