当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Silk sericin loaded alginate nanoparticles: Preparation and anti-inflammatory efficacy.

Silk sericin loaded alginate nanoparticles: Preparation and anti-inflammatory efficacy.

Abstract：

:In this study, silk sericin loaded alginate nanoparticles were prepared by the emulsification method followed by internal crosslinking. The effects of various silk sericin loading concentration on particle size, shape, thermal properties, and release characteristics were investigated. The initial silk sericin loadings of 20, 40, and 80% w/w to polymer were incorporated into these alginate nanoparticles. SEM images showed a spherical shape and small particles of about 71.30-89.50 nm. TGA analysis showed that thermal stability slightly increased with increasing silk sericin loadings. FTIR analysis suggested interactions between alginate and silk sericin in the nanoparticles. The release study was performed in acetate buffer at normal skin conditions (pH 5.5; 32 °C). The release profiles of silk sericin exhibited initial rapid release, consequently with sustained release. These silk sericin loaded alginate nanoparticles were further incorporated into topical hydrogel and their anti-inflammatory properties were studied using carrageenan-induced paw edema assay. The current study confirms the hypothesis that the application of silk sericin loaded alginate nanoparticle gel can inhibit inflammation induced by carrageenan.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Khampieng T,Aramwit P,Supaphol P

doi

10.1016/j.ijbiomac.2015.07.018

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

636-43

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(15)00479-1

journal_volume

80

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Pectin-non-starch nanofibers biocomposites as novel gastrointestinal-resistant prebiotics.

    abstract：:Incorporation of nanofibers of chitin (NC), lignocellulose (NLC) and bacterial cellulose (BNC) in pectin was studied to improve prebiotic activity and gastrointestinal resistance of the pectin-nanofibers biocomposites for protection of probiotics under simulated gastrointestinal conditions. The biocomposites were prep...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.10.011

    authors： Khorasani AC,Shojaosadati SA

    更新日期：2017-01-01 00:00:00

  • Zinc-chitosan nanoparticles induced apoptosis in human acute T-lymphocyte leukemia through activation of tumor necrosis factor receptor CD95 and apoptosis-related genes.

    abstract：:Chitosan (CS), a novel biomaterial is widely used as a drug nano-carrier for cancer treatments. Towards this aim, anticancer and antibacterial activities of CS-nanoparticles-linked zinc (Zn-CSNPs) were evaluated. The particle size of CSNPs was lowered (113.09 nm) compared to Zn-CSNPs (160.7 nm). Both nanoparticles (CS...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.017

    authors： Saravanakumar K,Jeevithan E,Chelliah R,Kathiresan K,Wen-Hui W,Oh DH,Wang MH

    更新日期：2018-11-01 00:00:00

  • The interaction between residues 62 and 193 play a key role in activity and structural stability of arginine kinase.

    abstract：:The purpose of this study is to clarify that the amino acid residues (Asp62 and Arg193) are responsible for the activity and stability of arginine kinase (AK). The amino acid residues Asp62 (D62) and Arg193 (R193) are strictly conserved in monomeric AKs and form an ion pair in the transition state analogue complex. In...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2011.05.022

    authors： Liu N,Wang JS,Wang WD,Pan JC

    更新日期：2011-10-01 00:00:00

  • Anti-inflammatory effects of vanadium-binding protein from Halocynthia roretzi in LPS-stimulated RAW264.7 macrophages through NF-κB and MAPK pathways.

    abstract：:Vanadium-binding protein (VBP) was separated from the blood of the fresh sea urchin Halocynthia roretzi through (NH4)2SO4 precipitation, Diethylaminoethyl Sepharose fast-flow ion-exchange chromatography, and Sephacryl S-200 high-resolution size-exclusion chromatography. The protein size and purification yield of VBP w...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.04.106

    authors： Kim AT,Kim DO

    更新日期：2019-07-15 00:00:00

  • Supramolecular structure and pasting/digestion behaviors of rice starches following concurrent microwave and heat moisture treatment.

    abstract：:From a supramolecular structure viewpoint, we concern how concurrent microwave and heat moisture treatment (M/HMT) tailors the pasting and digestion features of indica rice starch (IRS) and waxy rice starch (WRS), using combined analytical methods such as scanning electron microscopy and small-angle X-ray scattering. ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.05.189

    authors： Guo Y,Xu T,Li N,Cheng Q,Qiao D,Zhang B,Zhao S,Huang Q,Lin Q

    更新日期：2019-08-15 00:00:00

  • Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex.

    abstract：:An algal extracellular biopolymer (over 8.5 × 10(5)Da) composed of carbohydrates (52%) and protein (∼13%) has been isolated from a red alga Rhodella grisea growing in natural conditions by concentration of water medium, alcohol precipitation, dialysis and freeze-drying. This mucilagineous biopolymer contained xylose a...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2011.08.029

    authors： Nosáľová G,Capek P,Flešková D,Jureček L,Hindák F,Lukavský J,Cepák V,Ray B,Breierová E,Turjan J

    更新日期：2011-12-01 00:00:00

  • Preparation and structural characterization of surface modified microporous bacterial cellulose scaffolds: A potential material for skin regeneration applications in vitro and in vivo.

    abstract：:This study reports the fabrication of porogen-induced, surface-modified, 3-dimensionally microporous regenerated bacterial cellulose (rBC)/gelatin (3DMP rBC/G) scaffolds for skin regeneration applications. Round shaped gelatin microspheres (GMS), fabricated using a water-in-oil emulsion (WOE) method, were utilized as ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.06.044

    authors： Khan S,Ul-Islam M,Ikram M,Islam SU,Ullah MW,Israr M,Jang JH,Yoon S,Park JK

    更新日期：2018-10-01 00:00:00

  • Aqueous extraction of pectin from sour orange peel and its preliminary physicochemical properties.

    abstract：:Sour orange peel, a by-product of the fruit juice industry, was used as a source of pectin. The effects of temperature (75-95°C), time (30-90 min), and liquid-solid ratio (20-40, v/w) were investigated on yield, methoxylation degree (DE), and galacturonic acid content using a Box-Behnken design and response surface me...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.11.007

    authors： Hosseini SS,Khodaiyan F,Yarmand MS

    更新日期：2016-01-01 00:00:00

  • Structural characteristics and prebiotic effects of Semen coicis resistant starches (type 3) prepared by different methods.

    abstract：:In order to investigate the effects of different preparation methods on Semen coicis resistant starch, the structural properties and prebiotic effects of autoclaving treatment-purified S. coicis resistant starch (GP-SRS3), ultrasonic-autoclaving treatment-purified S. coicis resistant starch (UP-SRS3), enzyme-autoclavi...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.07.091

    authors： Bao C,Zeng H,Zhang Y,Zhang L,Lu X,Guo Z,Miao S,Zheng B

    更新日期：2017-12-01 00:00:00

  • Some biophysical applications of motional contrast in n.m.r. microscopy.

    abstract：:The principal advantage of the n.m.r. imaging method lies in the specific contrasts which are available. In this work we describe the use of velocity and diffusion contrast methods in biophysical applications and at microscopic spatial resolution. In the first example, involving water-protein interactions, the relatio...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(91)90045-v

    authors： Back PJ,Coy A,Xia Y,Callaghan PT,Diamante LM,Umbach SL

    更新日期：1991-06-01 00:00:00

  • Fabrication and characterization of PVA/Gum tragacanth/PCL hybrid nanofibrous scaffolds for skin substitutes.

    abstract：:In this work three dimensional biodegradable nanofiberous scaffolds containing poly(ε-caprolactone) (PCL), poly(vinyl alcohol) (PVA) and gum tragacanth (GT) were successfully fabricated through two nozzles electrospinning process. For this purpose, PVA/GT blend (Blend: B) solution (60:40wt%) was injected from one syri...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.10.042

    authors： Zarekhalili Z,Bahrami SH,Ranjbar-Mohammadi M,Milan PB

    更新日期：2017-01-01 00:00:00

  • Enhanced antibacterial activity of PEO-chitosan nanofibers with potential application in burn infection management.

    abstract：:Chitosan (CS) is a well-known biological macromolecule having numerous applications due to its exceptional properties especially in the form of nanofibers. The antibacterial activity is compromised when co-polymers are added to electrospun CS but, the reproducibility can be enhanced which is key to commercialization. ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.06.022

    authors： Abid S,Hussain T,Nazir A,Zahir A,Ramakrishna S,Hameed M,Khenoussi N

    更新日期：2019-08-15 00:00:00

  • Enzymatic phosphorylation of hair keratin enhances fast adsorption of cationic moieties.

    abstract：:The current study describes the in vitro phosphorylation of a human hair keratin, using protein kinase for the first time. Phosphorylation of keratin was demonstrated by (31)P NMR (Nuclear Magnetic Resonance) and Diffuse Reflectance Infrared Fourier Transform (DRIFT) techniques. Phosphorylation induced a 2.5 fold incr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.12.082

    authors： Volkov V,Cavaco-Paulo A

    更新日期：2016-04-01 00:00:00

  • Development of biopolymers based interpenetrating polymeric network of capecitabine: A drug delivery vehicle to extend the release of the model drug.

    abstract：:The research aims the development and optimization of capecitabine loaded interpenetrating polymeric network by ionotropic gelation method using polymers locust bean gum and sodium alginate by QbD approach. FMEA was performed to recognize the risks influencing CQAs. BBD was applied to study the effect of factors (poly...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.04.123

    authors： Upadhyay M,Adena SKR,Vardhan H,Yadav SK,Mishra B

    更新日期：2018-08-01 00:00:00

  • The differences between fungal α-glucan synthase determining pullulan synthesis and that controlling cell wall α-1,3 glucan synthesis.

    abstract：:The fungal α-glucan synthases (Agss) are multi-domain proteins catalyzing biosynthesis of cell wall α-1,3-glucan which determines cell wall integrity or fungal pathogenicity and pullulan which is a maltotriosyl polymer made of α-1,4 and α-1,6 bound glucose units. The Agss family can be divided into 11 groups, some of ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.06.147

    authors： Qi CY,Jia SL,Wei X,Yang G,Chi Z,Liu GL,Hu Z,Chi ZM

    更新日期：2020-11-01 00:00:00

  • A novel quaternized chitosan-melamine-glutaraldehyde resin for the removal of nitrate and phosphate anions.

    abstract：:A terpolymer of chitosan-melamine-glutaraldehyde was prepared for the first time and it was quaternized with glycidyl trimethyl ammonium chloride (GTMAC). The quaternized chitosan-melamine-glutaraldehyde resin (QCMGR) was found to be effective for the removal of nitrate and phosphate oxyanions. The resin was character...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.11.036

    authors： Sowmya A,Meenakshi S

    更新日期：2014-03-01 00:00:00

  • Toxic heavy metal cadmium removal using chitosan and polypropylene based fiber composite.

    abstract：:The aim of the present work was to evaluate the performance of polypropylene (PP)/sisal fiber (SF)/banana fiber (BF) and chitosan-based hybrid (chitosan(CS)/SF)/BF) composite materials for the adsorptive removal of cadmium (Cd) ions from water waste. Polypropylene is harnessed for its importance in forming strong comp...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.07.252

    authors： Alaswad SO,Lakshmi KB,Sudha PN,Gomathi T,Arunachalam P

    更新日期：2020-12-01 00:00:00

  • Cloning, overexpression, purification of bacteriocin enterocin-B and structural analysis, interaction determination of enterocin-A, B against pathogenic bacteria and human cancer cells.

    abstract：:In this present study, a gene (ent-B) encoding the bacteriocin enterocin-B was cloned, overexpressed and purified from Enterococcus faecium por1. The molecular weight of the bacteriocin enterocin-B was observed around 7.2 kDa and exhibited antimicrobial activity against several human pathogenic bacteria. The antimicro...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.05.002

    authors： Ankaiah D,Palanichamy E,Antonyraj CB,Ayyanna R,Perumal V,Ahamed SIB,Arul V

    更新日期：2018-09-01 00:00:00

  • Insights into anti-pathogenic activities of mannose lectins.

    abstract：:Carbohydrate-binding proteins, also known as lectins, are valuable tools for biotechnology, including pharmacological uses. Mannose lectins obtained from plant and animal sources are applied to protection and characterization of autoimmune diseases as well as defense proteins against pathogens. The presence of mannose...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijbiomac.2019.08.059

    authors： Dos Santos Silva PM,de Oliveira WF,Albuquerque PBS,Dos Santos Correia MT,Coelho LCBB

    更新日期：2019-11-01 00:00:00

  • Polyethyleneimine-protein interactions and implications on protein stability.

    abstract：:Protein stability assessment of seven model proteins in the presence of low molecular weight polyethyleneimine (PEI, MW 2000 Da) was performed. Thermodynamic stability, monitored by circular dichroism (CD) spectroscopy, showed that the polymer did not have a major effect on the melting temperature (T(m)) of the basic ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2010.04.003

    authors： Mazzaferro L,Breccia JD,Andersson MM,Hitzmann B,Hatti-Kaul R

    更新日期：2010-07-01 00:00:00

  • Preparation and characterization of bionanocomposite films based on potato starch/halloysite nanoclay.

    abstract：:In this research casting method was used to prepare potato starch based bio-nanocomposite films with halloysite nanoclay as the reinforcing materials. The composition included potato starch with 40% (w/w) of a mixture of sorbitol/glycerol (weight ratio of 3 to 1as plasticizer) with nanoclay (0-5% w/w). The films were ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.04.009

    authors： Sadegh-Hassani F,Mohammadi Nafchi A

    更新日期：2014-06-01 00:00:00

  • Biophysical characterization of the interaction between M2-1 protein of hRSV and quercetin.

    abstract：:hRSV is the major causative agent of acute respiratory infections. Among its eleven proteins, M2-1 is a transcription antiterminator, making it an interesting target for antivirals. Quercetin is a flavonol which inhibits some virus infectivity and replication. In the present work, the M2-1 gene was cloned, expressed a...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.11.033

    authors： Teixeira TS,Caruso ÍP,Lopes BR,Regasini LO,Toledo KA,Fossey MA,Souza FP

    更新日期：2017-02-01 00:00:00

  • Synthesis and characterization of schizophyllan nanogels via inverse emulsion using biobased materials.

    abstract：:Oxidized sucrose cross-linked Schizophyllan nanogel was successfully synthesized via inverse emulsion method for the first time. The synthesis process was conducted in the absence of both toxic cross-linker and organic solvent. The nanogel crosslinking network was prepared using fractionated coconut oil as the continu...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.119

    authors： Mousaviasl S,Saleh T,Shojaosadati SA,Boddohi S

    更新日期：2018-12-01 00:00:00

  • In vitro release and biological activities of Carum copticum essential oil (CEO) loaded chitosan nanoparticles.

    abstract：:In recent years, the unparalleled and functional properties of essential oils have been extensively reported, but the sensitivity of essential oils to environmental factors and their poor aqueous solubility have limited their applications in industries. Hence, we encapsulated CEO in chitosan nanoparticles by an emulsi...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.08.010

    authors： Esmaeili A,Asgari A

    更新日期：2015-11-01 00:00:00

  • Stabilization of collagen using plant polyphenol: role of catechin.

    abstract：:Collagen, a unique connective tissue protein finds extensive application as biocompatible biomaterial in wound healing, as drug carriers, cosmetics, etc. A work has been undertaken to study the stabilization of type I collagen using the plant polyphenol catechin. Catechin treated collagen fibres showed a shrinkage tem...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2005.08.005

    authors： Madhan B,Subramanian V,Rao JR,Nair BU,Ramasami T

    更新日期：2005-10-30 00:00:00

  • Convenient preparation of an antigenic oligosaccharide from white kidney bean powder: A useful plant oligosaccharide for synthesis of immunoactive glycopolymer.

    abstract：:Plant glycoproteins, especially allergenic glycoproteins such as pollen allergens, often carry antigenic N-glycans with α1-3 fucose and/or β1-2 xylose residue(s) on the trimannosyl core structure. We previously reported that one of such antigenic free-form N-glycans, Man3Xyl1Fuc1GlcNAc2 (M3FX) suppressed IL-4 producti...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.10.231

    authors： Kimura M,Ogura M,Akamatsu M,Sugimoto K,Maeda M,Nitoda T,Nagasawa-Fujimori H,Yamashita H,Kimura Y

    更新日期：2020-06-15 00:00:00

  • Facile fabrication of core-shell/bead-like ethylenediamine-functionalized Al-pillared montmorillonite/calcium alginate for As(V) ion adsorption.

    abstract：:In this study, a MT(Al)/calcium alginate [MT(Al)@CA] microsphere structure was prepared using sodium alginate (SA) and MT(Al). In order to achieve [MT(Al)@CA] microspheres with a high stability and chemical resistance, glutaraldehyde was used as the crosslinking agent to graft the microspheres and ethylenediamine (ED)...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.03.172

    authors： Song Y,Wang S,Yang LY,Yu D,Wang YG,Ouyang XK

    更新日期：2019-06-15 00:00:00

  • The antibacterial and anti-inflammatory investigation of Lawsonia Inermis-gelatin-starch nano-fibrous dressing in burn wound.

    abstract：:The aim of this study was to develop a new bioactive gelatin-oxidized starch nanofibers containing Lawsonia Inermis (henna) for treating second-degree burn wounds. Continuous, smooth, and bead-free fibers were obtained when the gelatin-starch ratio was 70/30.Additionally, the fiber dimeter was reduced with increasing ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.10.061

    authors： Hadisi Z,Nourmohammadi J,Nassiri SM

    更新日期：2018-02-01 00:00:00

  • Quantitative proteomic analysis of the effects of a GalNAc/Man-specific lectin CSL on yeast cells by label-free LC-MS.

    abstract：:A Ca(2+)-dependent GalNAc/Man-specific lectin (CSL) from Cyclina sinensis was isolated, and its stimulatory action was characterized in yeast. CSL showed a potent effect on the production of ethanol by Saccharomyces cerevisiae. In this work, the changes in the protein expression profiles of S. cerevisiae after 24h of ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.01.034

    authors： Liu S,Li L,Tong C,Zhao Q,Lukyanov PA,Chernikov OV,Li W

    更新日期：2016-04-01 00:00:00

  • Multiparticulate based thermosensitive intra-pocket forming implants for better treatment of bacterial infections in periodontitis.

    abstract：:Considering alarming projections in the prevalence of periodontitis, following study was undertaken to develop chitosan-vanillin crosslinked microspheres loaded in-situ gel (MLIG) implants containing ornidazole and doxycycline hyclate for the treatment of pocket infections. Firstly, microspheres were formulated and op...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.04.179

    authors： Yadav SK,Khan G,Bansal M,Thokala S,Bonde GV,Upadhyay M,Mishra B

    更新日期：2018-09-01 00:00:00