Deciphering the interactions of fish gelatine and hyaluronic acid in aqueous solutions.


:The interactions of fish gelatine (FG) with hyaluronic acid (HA) are studied in an aqueous environment at 25°C by turbidimetric titration, confocal scanning laser microscopy, dynamic light scattering, zeta potentiometry, spectrophotometry with methylene blue, and construction of state diagrams. FG forms soluble complexes with HA above a boundary pH (pHφ1), where both biopolymers are net-negatively charged, but develop insoluble complexes as liquid-state complex coacervates below pHφ1, where the two biopolymers are oppositely charged. The insoluble complexes are continuously aggregated with further acid titration, followed by immediate visible phase-separation when another boundary pH (pHp) is reached. The complex formation is mainly driven by electrostatic attractions rather than hydrogen bonding or hydrophobic interactions. The complex formation is promoted by increasing FG-to-HA weight ratio or total biopolymer concentration, or at a low ionic strength, but significantly suppressed in the presence of high ionic strength.


Int J Biol Macromol


Razzak MA,Kim M,Kim HJ,Park YC,Chung D




Has Abstract


2017-09-01 00:00:00












  • Quantitative proteomics to reveal the composition of Southern India spectacled cobra (Naja naja) venom and its immunological cross-reactivity towards commercial antivenom.

    abstract::Indian cobra (Naja naja) envenomation is frequently reported across Indian subcontinent. Geographical differences in the venom composition of a particular species of snake often leads to inconsistencies in the antivenom neutralization. Consequently, determining the venom proteome from every locale is necessary for the...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chanda A,Mukherjee AK

    更新日期:2020-10-01 00:00:00

  • Electrospraying of environmentally sustainable alginate microbeads for cosmetic additives.

    abstract::Polymer microbeads (MBs) for scrubbing additives have generally been prepared from non-biodegradable synthetic polymers. The worldwide pollution of the marine ecosystem by microplastics urgently demands novel environment-friendly MBs. In this study, Ca-alginate MBs were fabricated by electrospraying an aqueous alginat...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Bae SB,Nam HC,Park WH

    更新日期:2019-07-15 00:00:00

  • Role of phosphorylation of phosvitin in the phase transformation of mineralization.

    abstract::Phosvitin is a unique highly phosphorylated protein that plays a role in the regulation of mineralization. This study investigated the role of phosphorylation of phosvitin in the phase transformation of calcium phosphate in the mineralization solution. Partially dephosphorylated phosvitins (T1, T2, T3 and T4) were pre...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Zhang X,Huang X,Ma M

    更新日期:2017-08-01 00:00:00

  • Comparison of two starch-based flocculants with polyacrylamide for the simultaneous removal of phosphorus and turbidity from simulated and actual wastewater samples in combination with FeCl3.

    abstract::Two laboratory-made cationic starch-based flocculants (St-CTA and St-AD) with different chain architectures were used to simultaneously remove phosphorus and turbidity from two simulated wastewaters and one actual wastewater with laboratory and pilot scales, respectively, in conjunction with FeCl3. A commercial polyac...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Hu P,Ren J,Hu X,Yang H

    更新日期:2021-01-15 00:00:00

  • Biocompatible, drug-loaded anti-adhesion barrier using visible-light curable furfuryl gelatin derivative.

    abstract::Recently, many of studies have been attempted to determine how to decrease adhesion. To effectively prevent adhesion, decrease in unnecessary surgical procedures, prevention of contact with other tissue, and drug treatment for inflammation are required. However, current anti-adhesion materials have disadvantages. To s...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Kim EH,Kim JW,Han GD,Noh SH,Choi JH,Choi C,Kim MK,Nah JW,Kim TY,Ito Y,Son TI

    更新日期:2018-12-01 00:00:00

  • Computational design of Bacillus licheniformis RN-01 levansucrase for control of the chain length of levan-type fructooligosaccharides.

    abstract::Levansucrase (LS) from Gram-positive bacteria generally produces a large quantity of levan polymer, a polyfructose with glucose at the end (GFn) but a small quantity of levan-type fructooligosaccharides (LFOs). The properties of levan and LFOs depend on their chain lengths, thereby determining their potential applicat...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Kanjanatanin P,Pichyangkura R,Sitthiyotha T,Charoenwongpaiboon T,Wangpaiboon K,Chunsrivirot S

    更新日期:2019-11-01 00:00:00

  • Preparation and property of a biantenna macromolecule based on polysialic acid.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Lei Y,Wu M,Wang J,Zhang H,Zhan X,Sun Z,Wu J

    更新日期:2020-07-15 00:00:00

  • Changes of digestive and fermentation properties of Sargassum pallidum polysaccharide after ultrasonic degradation and its impacts on gut microbiota.

    abstract::The in vitro digestive and fermentation properties of Sargassum pallidum polysaccharide (SPP) after ultrasound degradation were investigated. The results showed that SPP and its degraded fractions were not affected by human saliva, but slightly degraded by breaking glycosidic bonds under simulated gastrointestinal dig...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Yuan D,Li C,You L,Dong H,Fu X

    更新日期:2020-12-01 00:00:00

  • Both beta sheet breaker and alpha helix forming pentapeptide inhibits protein fibrillation: Implication for the treatment of amyloid disorders.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Siddiqi MK,Majid N,Alam P,Malik S,Alam A,Rajan S,Ajmal MR,Khan RH

    更新日期:2020-01-15 00:00:00

  • Silk as templates for hydroxyapatite biomineralization: A comparative study of Bombyx mori and Antheraea pernyi silkworm silks.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Zhang H,You R,Yan K,Lu Z,Fan Q,Li X,Wang D

    更新日期:2020-12-01 00:00:00

  • New xylanolytic enzyme from Geobacillus galactosidasius BS61 from a geothermal resource in Turkey.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Sari B,Faiz O,Genc B,Sisecioglu M,Adiguzel A,Adiguzel G

    更新日期:2018-11-01 00:00:00

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Takeda M,Nakamori T,Hatta M,Yamada H,Koizumi J

    更新日期:2003-12-01 00:00:00

  • Effect of plasticizers on microstructure, compatibility and mechanical property of hydroxypropyl methylcellulose/hydroxypropyl starch blends.

    abstract::Polymer film blends of hydroxypropyl methylcellulose (HPMC) and hydroxypropyl starch (HPS) were produced with an incorporation of three different plasticizers, including polyethylene glycol (PEG), glycerol and 1, 2-propylene glycol (PG) respectively, and the influence of these plasticizers were compared and studied by...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Zhang L,Wang XF,Liu H,Yu L,Wang Y,Simon GP,Qian J

    更新日期:2018-11-01 00:00:00

  • The effect of deep eutectic solvents on catalytic function and structure of bovine liver catalase.

    abstract::Aqueous solutions of reline and glyceline, the most common deep eutectic solvents, were used as a medium for Catalase reaction. By some spectroscopic methods such as UV-vis, fluorescence and circular dichroism (CD) function and structure of Catalase were investigated in aqueous solutions of reline and glyceline. These...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Harifi-Mood AR,Ghobadi R,Divsalar A

    更新日期:2017-02-01 00:00:00

  • Alginate-chitosan/hydroxyapatite polyelectrolyte complex porous scaffolds: preparation and characterization.

    abstract::Porous scaffolds composed of alginate (AG) and chitosan (CS) were fabricated by combining the formation of polyelectrolyte complex (PEC) with freeze-drying. The AG scaffold was used as a framework with uniformly distributed and interconnected pore structure. The chitosan or chitosan/hydroxyapatite (CS/HA) composite so...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Han J,Zhou Z,Yin R,Yang D,Nie J

    更新日期:2010-03-01 00:00:00

  • Characterization of a recombinant d-allulose 3-epimerase from Agrobacterium sp. ATCC 31749 and identification of an important interfacial residue.

    abstract::d-Allulose 3-epimerase (DAEase) catalyzes the epimerization between d-fructose and d-allulose. We had PCR-cloned and overexpressed the gene encoding Agrobacterium sp. ATCC 31749 DAEase (AsDAEase) in Escherichia coli. A high yield of active AsDAEase, 35,300U/L or 1350U/g of wet cells, was acquired with isopropyl β-d-1-...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Tseng WC,Chen CN,Hsu CT,Lee HC,Fang HY,Wang MJ,Wu YH,Fang TY

    更新日期:2018-06-01 00:00:00

  • Physical properties imparted by genipin to chitosan for tissue regeneration with human stem cells: A review.

    abstract::Genipin is a fully assessed non-cytotoxic crosslinking compound. The chitosan|genipin physical properties such as morphology, roughness, porosity, hydrophilicity, ζ-potential, surface area and surface energy exert control over cell adhesion, migration, phenotype maintenance and intracellular signaling in vitro, and ce...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章,评审


    authors: Muzzarelli RA,El Mehtedi M,Bottegoni C,Gigante A

    更新日期:2016-12-01 00:00:00

  • Biophysical insight into structure-function relation of Allium sativum Protease Inhibitor by thermal, chemical and pH-induced modulation using comprehensive spectroscopic analysis.

    abstract::In this study, we have analyzed the structural and functional changes in the nature of Allium sativum Protease Inhibitor (ASPI) on undergoing various denaturation with variable range of pH, temperature and urea (at pH 8.2). ASPI being anti-tryptic in nature has native molecular mass of ∼15kDa. The conformational stabi...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Shamsi TN,Parveen R,Naz H,Haque MA,Fatima S

    更新日期:2017-10-01 00:00:00

  • Shelf life extension of wheat bread by alhydwan flour and Carboxymethylcellulose and improvement of their quality characteristics, dough rheological and microstructure.

    abstract::Alhydwan, has been used in bakery products for many years in South of Yemen. Alhydwan primary function in bakery products is to inhibit moisture content during storage, leading to improved shelf life. However, as a fresh strategy to bread staling, no extensive study has been conducted to evaluate its potential. The pr...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Ammar AF,Siddeeg A,Aqlan FM,Howladar SM,Refai MY,Afifi M,Ali HA,Hajjar D,Sulamain MGM,Chamba MVM,Kimani BG,Saleh A,Baeshen M

    更新日期:2020-08-01 00:00:00

  • A β-glucan from Grifola frondosa effectively delivers therapeutic oligonucleotide into cells via dectin-1 receptor and attenuates TNFα gene expression.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Cui H,Zhu X,Huo Z,Liao B,Huang J,Wang Z,Song C,Hu X,Fang J

    更新日期:2020-04-15 00:00:00

  • Magnetic chitosan composite as a green support for anchoring diphenyl diselenide as a biocatalyst for the oxidation of sulfides.

    abstract::Development of efficient, inexpensive and recyclable catalysts for a reaction under mild and green reaction conditions is still a very marvelous topic. In this work, diphenyl diselenide stabilized on magnetic chitosan as a novel, highly efficient, ecologically safe, cost-effective and magnetically recoverable heteroge...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Rangraz Y,Nemati F,Elhampour A

    更新日期:2018-10-01 00:00:00

  • Fabrication and characterization of novel bilayer scaffold from nanocellulose based aerogel for skin tissue engineering applications.

    abstract::The aim of this study was to fabricate a novel bilayer scaffold containing cellulose nanofiber/poly (vinyl) alcohol (CNF/PVA) to evaluate its potential use in skin tissue engineering. Here, the scaffolds were fabricated using a novel one-step freeze-drying technique with two different concentrations of the aforementio...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Ghafari R,Jonoobi M,Amirabad LM,Oksman K,Taheri AR

    更新日期:2019-09-01 00:00:00

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chang J,Lee YS,Fang SJ,Park DJ,Choi YL

    更新日期:2013-10-01 00:00:00

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    abstract::Water-soluble chitosan-based core-shell particles that contained changeable cores were successfully applied to anchor carbon dioxide. The entrapment capacity of the particles for carbon dioxide (EC) depended on the cores. It was found that EC of the particles contained aqueous cores was higher than that of the beads w...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Dong Y,Fu Y,Lin X,Xiao C

    更新日期:2016-08-01 00:00:00

  • Scaffolds containing chitosan, gelatin and graphene oxide for bone tissue regeneration in vitro and in vivo.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Saravanan S,Chawla A,Vairamani M,Sastry TP,Subramanian KS,Selvamurugan N

    更新日期:2017-11-01 00:00:00

  • Physicochemical and structural properties of sago starch.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Du C,Jiang F,Jiang W,Ge W,Du SK

    更新日期:2020-12-01 00:00:00

  • Biosynthesis of Ag nanoparticles using isolated bacteria from contaminated sites and its application as an efficient catalyst for hydrazine electrooxidation.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Rostami H,Khosravi F,Mohseni M,Rostami AA

    更新日期:2018-02-01 00:00:00

  • Influence of the ionic liquid 1-butyl-3-methylimidazolium bromide on amyloid fibrillogenesis in lysozyme: Evidence from photophysical and imaging studies.

    abstract::Many proteins can abnormally fold to form pathological amyloid deposits/aggregates that are responsible for various degenerative disorders called amyloidosis. Here we have examined the anti-amyloidogenic potency of an ionic liquid, 1-butyl-3-methylimidazolium bromide, using lysozyme as a model system. Thioflavin T flu...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Basu A,Bhattacharya SC,Kumar GS

    更新日期:2018-02-01 00:00:00

  • Effect of different combinations of maltodextrin, gum arabic and whey protein concentrate on the encapsulation behavior and oxidative stability of spray dried drumstick (Moringa oleifera) oil.

    abstract::The objective of the present study was to investigate the effect of different combinations of carrier agents (Maltodextrin, gum arabic and whey protein concentrate) on the emulsion properties, encapsulation efficiency and oxidative stability of encapsulated drumstick oil powder (EDOP), produced by spray drying to incr...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Premi M,Sharma HK

    更新日期:2017-12-01 00:00:00

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Li H,Yuan Z,Shang X,Shang H,Liu J,Darwesh OM,Li C,Fang J

    更新日期:2020-12-31 00:00:00