Abstract:
:Autochthonous pig breeds represent an important genetic reserve to be utilized mainly for the production of typical products. To explore its genetic variability, here we present for the first time whole genome sequencing data and SNPs discovered in a male domestic Nero Siciliano pig compared to the last pig reference genome Sus scrofa11.1.A total of 346.8 million paired reads were generated by sequencing. After quality control, 99.03% of the reads were mapped to the reference genome, and over 11 million variants were detected.Additionally, we evaluated sequence diversity in 21 fitness-related loci selected based on their biological function and/or their proximity to relevant QTLs. We focused on genes that have been related to environmental adaptation and reproductive traits in previous studies regarding local breeds. A total of 6,747 variants were identified resulting in a rate of 1 variant every ~276 bases. Among these variants 1,132 were novel to the dbSNP151 database. This study represents a first step in the genetic characterization of Nero Siciliano pig and also provides a platform for future comparative studies between this and other swine breeds.
journal_name
Genet Mol Bioljournal_title
Genetics and molecular biologyauthors
D'Alessandro E,Giosa D,Sapienza I,Giuffrè L,Cigliano RA,Romeo O,Zumbo Adoi
10.1590/1678-4685-GMB-2018-0169subject
Has Abstractpub_date
2019-07-01 00:00:00pages
594-602issue
3eissn
1415-4757issn
1678-4685pii
S1415-47572019005021102journal_volume
42pub_type
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