Identification and detection of a novel human endogenous retrovirus-related gene, and structural characterization of its related elements.

abstract：:Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration. This study was aimed at investigating the methylation level of EGF gene throughout liver regeneration. DNA of liver tissue fr...

journal_title：Genetics and molecular biology

authors： Li D,Fan J,Li Z,Xu C

更新日期：2014-06-01 00:00:00

abstract：:Despite their ecological and economical importance, fishes of the family Ariidae are still genetically and cytogenetically poorly studied. Among the 133 known species of ariids, only eight have been karyotyped. Cytogenetic analyses performed on Genidens barbus and Sciades herzbergii revealed that both species have 2n ...

journal_title：Genetics and molecular biology

authors： Nirchio M,Martinez ER,Foresti F,Oliveira C

更新日期：2010-04-01 00:00:00

abstract：:A detailed study of putative recombination events and their evolution frequency in the whole genome of the currently known members of the family Tombusviridae, comprising 79 accessions retrieved from the international databases, was carried out by using the RECCO and RDP version 3.31β algorithms. The first program all...

journal_title：Genetics and molecular biology

authors： Boulila M

更新日期：2011-10-01 00:00:00

abstract：:The common everyday use of medicinal plants is an ancient, and still very widespread practice, whereby the need for studies on their possible toxicity and mutagenic properties. The species Coccoloba mollis has been much used in phytotherapy, mainly in cases involving loss of memory and stress. In order to investigate ...

journal_title：Genetics and molecular biology

authors： Tsuboy MS,Marcarini JC,Ferreira DT,Ferraz ER,Chequer FM,de Oliveira DP,Ribeiro LR,Mantovani MS

更新日期：2010-07-01 00:00:00

abstract：:The function of gene body DNA methylation in alternative splicing, and its relation to disease pathogenesis is not fully elucidated. The gene for familial Mediterranean fever (MEFV) encodes the pyrin protein and contains a 998 bp CpG island, covering the second exon, which is differentially methylated in FMF patients ...

journal_title：Genetics and molecular biology

authors： Erdem GC,Erdemir S,Abaci I,Aydin AKK,Everest E,Turanli ET

更新日期：2017-07-01 00:00:00

abstract：:The Morato's Digger Toad, Proceratophrys moratoi, is a critically endangered toad species with a marked population decline in southern Brazilian Cerrado. Despite this, new populations are being discovered, primarily in the northern part of the distribution range, which raises a number of questions with regard to the c...

journal_title：Genetics and molecular biology

authors： Arruda MP,Costa WP,Recco-Pimentel SM

更新日期：2017-04-01 00:00:00

abstract：:Xenobiotics can trigger degranulation of eosinophils and mast cells. In this process, the cells release several substances leading to bronchial hyperactivity, the main feature of atopic asthma (AA). GSTM1 and GSTT1 genes encode enzymes involved in the inactivation of these compounds. Both genes are polymorphic in huma...

journal_title：Genetics and molecular biology

authors： Lima CS,Néri IA,Lourenço GJ,Faria IC,Ribeiro JD,Bertuzzo CS

更新日期：2010-07-01 00:00:00

abstract：:Population genetics studies the distributions and changes in population allele frequencies in response to processes, such as mutation, natural selection, gene flow, and genetic drift. Researchers daily manage genetic, biological, and environmental data of the samples, storing them in text files or spreadsheets, which ...

journal_title：Genetics and molecular biology

authors： Elias DE,Rueda ECR

更新日期：2020-05-29 00:00:00

abstract：:Tabebuia sp. is native to tropical rain forests throughout Central and South America. Although the biological and pharmacological effects of bark extracts have been intensely studied, little is known on the extract obtained from the flower. Herein, the genotoxic potential of a flower extract from T. impetiginosa ("ipê...

journal_title：Genetics and molecular biology

authors： Lemos OA,Sanches JC,Silva IE,Silva ML,Vinhólis AH,Felix MA,Santos RA,Cecchi AO

更新日期：2012-04-01 00:00:00

abstract：:The allelic frequencies of 12 short tandem repeat loci were obtained from a sample of 307 unrelated individuals living in Macapá, a city in the northern Amazon region, Brazil. These loci are the most commonly used in forensics and paternity testing. Based on the allele frequency obtained for the population of Macapá, ...

journal_title：Genetics and molecular biology

authors： da Costa Francez PA,Rodrigues EM,Frazão GF,Dos Reis Borges ND,Dos Santos SE

更新日期：2011-01-01 00:00:00

abstract：:In order to understand the genetic ancestry and mitochondrial DNA (mtDNA) diversity of current Colombian horse breeds we sequenced a 364-bp fragment of the mitocondrial DNA D-loop in 116 animals belonging to five Spanish horse breeds and the Colombian Paso Fino and Colombian Creole cattle horse breeds. Among Colombian...

journal_title：Genetics and molecular biology

authors： Jimenez LM,Mendez S,Dunner S,Cañón J,Cortés O

更新日期：2012-12-01 00:00:00

abstract：:Topoisomerase II inhibitors are effective chemotherapeutic agents in the treatment of cancer, in spite of being associated with the development of secondary leukemia. Our purpose was to determine the effects of etoposide on different genomic regions, aiming at discovering whether there are preferential sites which can...

journal_title：Genetics and molecular biology

authors： Brassesco MS,Montaldi AP,Sakamoto-Hojo ET

更新日期：2009-01-01 00:00:00

abstract：:A wide array of molecular markers has been used to investigate the genetic diversity among common bean species. However, the best combination of markers for studying such diversity among common bean cultivars has yet to be determined. Few reports have examined the genetic diversity of the carioca bean, commercially on...

journal_title：Genetics and molecular biology

authors： Küpper Cardoso Perseguini JM,Chioratto AF,Zucchi MI,Colombo CA,Carbonell SA,Costa Mondego JM,Gazaffi R,Franco Garcia AA,de Campos T,de Souza AP,Rubiano LB

更新日期：2011-01-01 00:00:00

abstract：:The PPARγ nuclear receptor regulates the expression of genes involved in lipid and carbohydrate metabolism, and it has protective effects in some patients with type 2 diabetes. Nevertheless, the therapeutic value of the PPARγ nuclear receptor protein is limited due to the secondary effects of some PPARγ ligands. Becau...

journal_title：Genetics and molecular biology

authors： Lizcano F,Vargas D

更新日期：2013-03-01 00:00:00

abstract：:Indica and japonica are two main subspecies of Asian cultivated rice (Oryza sativa L.) that differ clearly in morphological and agronomic traits, in physiological and biochemical characteristics and in their genomic structure. However, the proteins and genes responsible for these differences remain poorly characterize...

journal_title：Genetics and molecular biology

authors： Yang Y,Zhu K,Xia H,Chen L,Chen K

更新日期：2014-10-01 00:00:00

abstract：:Alpha-1-antitrypsin (AAT) plays an important role in the pathogenesis of emphysema, the pathological lesion underlying the majority of the manifestations of Chronic Obstructive Pulmonary Disease (COPD). In this study we tested the hypothesis that common AAT polymorphisms influence the risk of developing COPDs. We inve...

journal_title：Genetics and molecular biology

authors： Denden S,Khelil AH,Knani J,Lakhdar R,Perrin P,Lefranc G,Chibani JB

更新日期：2010-01-01 00:00:00

abstract：:The population of India harbors one of the world's most highly diverse gene pools, owing to the influx of successive waves of immigrants over regular periods in time. Several phylogenetic studies involving mitochondrial DNA and Y chromosomal variation have demonstrated Europeans to have been the first settlers in Indi...

journal_title：Genetics and molecular biology

authors： Tiwari SK,Sharma V,Sharma VK,Gopi M,Saikant R,Nandan A,Bardia A,Gunisetty S,Katikala P,Habeeb MA,Khan AA,Habibullah CM

更新日期：2011-04-01 00:00:00

abstract：:Lupinus albescens is a resistant cover plant that establishes symbiotic relationships with bacteria belonging to the Bradyrhizobium genus. This symbiosis helps the development of these plants in adverse environmental conditions, such as the ones found in arenized areas of Southern Brazil. This work studied three Brady...

journal_title：Genetics and molecular biology

authors： Granada CE,Vargas LK,Sant'Anna FH,Balsanelli E,Baura VA,Oliveira Pedrosa F,Souza EM,Falcon T,Passaglia LMP

更新日期：2018-04-01 00:00:00

abstract：:Birth defects (BDs) are functional and structural alterations in embryonic or fetal development. With an incidence of approximately 3-5%, BDs are a leading cause of infant mortality and lifelong disability. A population-based prospective case-control study was conducted for one year with 5204 infants, between March 1s...

journal_title：Genetics and molecular biology

authors： Oliveira-Brancati CIF,Ferrarese VCC,Costa AR,Fett-Conte AC

更新日期：2020-02-10 00:00:00

abstract：:Oral Lichen Planus (OLP) is an oral inflammatory condition, mediated by host immune system reaction, presenting basal membrane damages with inflammatory lesions in the mouth and/or skin. In this study, the role of functional polymorphisms in the MBL2 gene, encoding for Mannose-Binding Protein C (MBP-C), a member of th...

journal_title：Genetics and molecular biology

authors： Polesello V,Segat L,Biasotto M,Ottaviani G,Gobbo M,Di Lenarda R,Crovella S,Zupin L

更新日期：2019-01-01 00:00:00

abstract：:Ample evidence suggests that cancer is triggered by mutagenic damage and diets or supplements capable of reducing such incidences can be related to the prevention of neoplasy development or to an improvement in life quality of patients who undergo chemotherapy. This research aimed to evaluate the antimutagenic and ant...

journal_title：Genetics and molecular biology

authors： Oliveira RJ,Salles MJ,da Silva AF,Kanno TY,Lourenço AC,Leite Vda S,Matiazi HJ,Pesarini JR,Ribeiro LR,Mantovani MS

更新日期：2013-09-01 00:00:00

abstract：:The aim of this study was to estimate the components of variance and genetic parameters for the visual scores which constitute the Morphological Evaluation System (MES), such as body structure (S), precocity (P) and musculature (M) in Nellore beef-cattle at the weaning and yearling stages, by using threshold Bayesian ...

journal_title：Genetics and molecular biology

authors： de Faria CU,Koury W Jr,Magnabosco CU,de Albuquerque LG,Bezerra LA,Lôbo RB

更新日期：2009-10-01 00:00:00

abstract：:Breast cancer (BC) is the most prevalent type worldwide, besides being one of the most common causes of death among women. It has been suggested that sporadic BC is most likely caused by low-penetrance genes, including those involved in DNA repair mechanisms. Furthermore, the accumulation of DNA damage may contribute ...

journal_title：Genetics and molecular biology

authors： Santos RA,Teixeira AC,Mayorano MB,Carrara HH,Andrade JM,Takahashi CS

更新日期：2010-10-01 00:00:00

abstract：:Tandem repeats (microsatellites or SSRs) are molecular markers with great potential for plant genetic studies. Modern strategies include the transfer of these markers among widely studied and orphan species. In silico analyses allow for studying distribution patterns of microsatellites and predicting which motifs woul...

journal_title：Genetics and molecular biology

authors： da Maia LC,de Souza VQ,Kopp MM,de Carvalho FI,de Oliveira AC

更新日期：2009-10-01 00:00:00

abstract：:Phylogenetic niche conservatism can be investigated at multiple scales on an explicit geographical context. Haplotype-based comparative analyses of lineages occupying the same region, and thus subjected to similar environmental factors, allow decoupling shared evolutionary and ecological patterns, as well as multiple ...

journal_title：Genetics and molecular biology

authors： Barros MJF,Silva-Arias GA,Segatto ALA,Reck-Kortmann M,Fregonezi JN,Diniz-Filho JAF,Freitas LB

更新日期：2020-04-27 00:00:00

abstract：:Rhagomys rufescens (Rodentia: Sigmodontinae) is an endemic species of the Atlantic forest from Southern and Southeastern Brazil. Some authors consider Rhagomys as part of the tribe Thomasomyini; but its phylogenetic relationships remain unclear. Chromosomal studies on eight specimens of Rhagomys rufescens revealed a d...

journal_title：Genetics and molecular biology

authors： Testoni AF,Althoff SL,Nascimento AP,Steiner-Souza F,Sbalqueiro IJ

更新日期：2010-07-01 00:00:00

abstract：:Trypoxylon is a genus of solitary crabronid wasps whose population genetics is poorly known. The purpose of the present study was to investigate the genetic variation and differentiation among five populations of Trypoxylon albitarse, a species widely distributed throughout the Neotropics, with records from Panama to ...

journal_title：Genetics and molecular biology

authors： Bergamaschi AC,Lama MA

更新日期：2015-12-01 00:00:00

abstract：:Cannabinoids, flavonoids, and stilbenoids have been identified in the annual dioecious plant Cannabis sativa L. Of these, the cannabinoids are the best known group of this plant's natural products. Polyketide synthases (PKSs) are responsible for the biosynthesis of diverse secondary metabolites, including flavonoids a...

journal_title：Genetics and molecular biology

authors： Flores-Sanchez IJ,Linthorst HJ,Verpoorte R

更新日期：2010-10-01 00:00:00

abstract：:More than 90% of birds are socially monogamous, although genetic studies indicate that many are often not sexually monogamous. In the present study, DNA fingerprinting was used to estimate the genetic relationships between nestlings belonging to the same broods to evaluate the mating system in the socially monogamous ...

journal_title：Genetics and molecular biology

authors： Caparroz R,Miyaki CY,Baker AJ

更新日期：2011-01-01 00:00:00

abstract：:The usefulness of IRAP (inter-retrotransposon amplified polymorphism) and ITS-RFLP (restriction of PCR-amplified internal transcribed spacers of the rDNA) markers in the analysis of 39 Pyrenophora graminea isolates was determined. Each marker system could discriminate between all of the isolates in detecting polymorph...

journal_title：Genetics and molecular biology

authors： Zein I,Jawhar M,Arabi MI

更新日期：2010-04-01 00:00:00