Clinical significance of miR-140-5p and miR-193b expression in patients with breast cancer and relationship to IGFBP5.

abstract：:The applicability of mitochondrial nad6 sequences to studies of DNA and population variability in Lepidoptera was tested in four species of economically important moths and one of wild butterflies. The genetic information so obtained was compared to that of cox1 sequences for two species of Lepidoptera. nad6 primers a...

journal_title：Genetics and molecular biology

authors： Silva-Brandão KL,Lyra ML,Santos TV,Seraphim N,Albernaz KC,Pavinato VA,Martinelli S,Cônsoli FL,Omoto C

更新日期：2011-10-01 00:00:00

abstract：:Peanut (Arachis hypogaea) is the fifth most produced oil crop worldwide. Besides lack of water, fungal diseases are the most limiting factors for the crop. Several species of Arachis are resistant to certain pests and diseases. This study aimed to successfully cross the A-genome with B-K-A genome wild species previous...

journal_title：Genetics and molecular biology

authors： Fávero AP,Dos Santos RF,Simpson CE,Valls JF,Vello NA

更新日期：2015-07-01 00:00:00

abstract：:Glucose-6-phosphate dehydrogenase deficiency (G6PDd) and Duffy-negative blood group are two red blood cells variants that confer protection against malaria. In this study, the distribution of the most common G6PD variants (G6PD*A-, GGPD*A and G6PD Mediterranean) and the major alleles of the Duffy blood group (FY*A, FY...

journal_title：Genetics and molecular biology

authors： Oliveira HSS,Silva ANLMD,Andrade GB,Gaia KC,Costa GLC,Santos ÂKCRD,Guerreiro JF

更新日期：2018-10-01 00:00:00

abstract：:The PPARγ nuclear receptor regulates the expression of genes involved in lipid and carbohydrate metabolism, and it has protective effects in some patients with type 2 diabetes. Nevertheless, the therapeutic value of the PPARγ nuclear receptor protein is limited due to the secondary effects of some PPARγ ligands. Becau...

journal_title：Genetics and molecular biology

authors： Lizcano F,Vargas D

更新日期：2013-03-01 00:00:00

abstract：:Cytogenetic studies in birds are still scarce compared to other vertebrates. Woodcreepers (Dendrocolaptidae) are part of a highly specialized group within the Suboscines of the New World. They are forest birds exclusive to the Neotropical region and similar to woodpeckers, at a comparable evolutionary stage. This pape...

journal_title：Genetics and molecular biology

authors： de Oliveira Barbosa M,da Silva RR,de Sena Correia VC,Dos Santos LP,Garnero Adel V,Gunski RJ

更新日期：2013-03-01 00:00:00

abstract：:The roots of the understorey shrub Carapichea ipecacuanha (ipecac) have medicinal properties, and the uprooting of wild plants has supplied most of the world demand for this species. Although under severe population decline, C. ipecacuanha lacks legal protection. In the wild, the aerial stems of ipecac clump together ...

journal_title：Genetics and molecular biology

authors： de Oliveira LO,Venturini BA,Rossi AA,Hastenreiter SS

更新日期：2010-01-01 00:00:00

abstract：:The function of gene body DNA methylation in alternative splicing, and its relation to disease pathogenesis is not fully elucidated. The gene for familial Mediterranean fever (MEFV) encodes the pyrin protein and contains a 998 bp CpG island, covering the second exon, which is differentially methylated in FMF patients ...

journal_title：Genetics and molecular biology

authors： Erdem GC,Erdemir S,Abaci I,Aydin AKK,Everest E,Turanli ET

更新日期：2017-07-01 00:00:00

abstract：:The Morato's Digger Toad, Proceratophrys moratoi, is a critically endangered toad species with a marked population decline in southern Brazilian Cerrado. Despite this, new populations are being discovered, primarily in the northern part of the distribution range, which raises a number of questions with regard to the c...

journal_title：Genetics and molecular biology

authors： Arruda MP,Costa WP,Recco-Pimentel SM

更新日期：2017-04-01 00:00:00

abstract：:Hereditary cancer risk assessment is a multidisciplinary and dynamic process, with the purpose of estimating probabilities of germline mutations in cancer susceptibility genes and assessing empiric risks of cancer based on personal and family histories, in order to offer clinical and molecular diagnoses and clinical m...

journal_title：Genetics and molecular biology

authors： Gomy I,Diz Mdel P

更新日期：2016-05-13 00:00:00

abstract：:In the present study, water buffalo MHC (Bubu)-DRB cDNA was cloned and characterized. The 1022 base long-amplified cDNA product encompassed a single open reading frame of 801 bases that coded for 266 amino acids. The Bubu-DRB sequence showed maximum homology with the BoLA-DRB3*0101 allele of cattle. A total of seven a...

journal_title：Genetics and molecular biology

authors： Naskar S,Deb SM,Niranjan SK,Kumar S,Sharma D,Sakaram D,Sharma A

更新日期：2012-01-01 00:00:00

abstract：:During the last decade, microsatellites (short tandem repeats or STRs) have been successfully used for animal genetic identification, traceability and paternity, although in recent year single nucleotide polymorphisms (SNPs) have been increasingly used for this purpose. An efficient SNP identification system requires ...

journal_title：Genetics and molecular biology

authors： Fernández ME,Goszczynski DE,Lirón JP,Villegas-Castagnasso EE,Carino MH,Ripoli MV,Rogberg-Muñoz A,Posik DM,Peral-García P,Giovambattista G

更新日期：2013-07-01 00:00:00

abstract：:Tissue samples from mosquitoes artificially infected with Zika virus and shown to be positive by RT-qPCR were reexamined by RT-PCR. Using these samples we compared the two methods employed in virus RNA detection for vector competence studies. Results demonstrated that, albeit useful, RT-PCR gave false negatives with l...

journal_title：Genetics and molecular biology

authors： Paiva MHS,Guedes DRD,Leal WS,Ayres CFJ

更新日期：2017-07-01 00:00:00

abstract：:The genus Phanaeus is included in the tribe Phanaeini, one of the most diverse tribes within the subfamily Scarabaeinae in terms of chromosomal characteristics. However, so far the species of this genus were not studied with differential cytogenetic techniques, limiting any inference of the probable mechanisms respons...

journal_title：Genetics and molecular biology

authors： Arcanjo A,Cabral-de-Mello DC,Martins C,de Cássia de Moura R,de Souza MJ

更新日期：2013-09-01 00:00:00

abstract：:Oral Lichen Planus (OLP) is an oral inflammatory condition, mediated by host immune system reaction, presenting basal membrane damages with inflammatory lesions in the mouth and/or skin. In this study, the role of functional polymorphisms in the MBL2 gene, encoding for Mannose-Binding Protein C (MBP-C), a member of th...

journal_title：Genetics and molecular biology

authors： Polesello V,Segat L,Biasotto M,Ottaviani G,Gobbo M,Di Lenarda R,Crovella S,Zupin L

更新日期：2019-01-01 00:00:00

abstract：:This study shows that sampling maternal DNA from hatched and abandoned eggshells is a viable noninvasive strategy for studying the genetics of rare or endangered tropical birds, as exemplified here by the Brazilian Merganser (Mergus octosetaceus). Eighteen microsatellites were isolated from enriched libraries and nine...

journal_title：Genetics and molecular biology

authors： Maia TA,Vilaça ST,Silva LRD,Santos FR,Dantas GPM

更新日期：2017-10-01 00:00:00

abstract：:Screening of mutations that cause β-thalassaemia in the Bangladeshi population led to the identification of a patient with a combination of two rare mutations, Hb Monroe and HBB: -92 C > G. The β-thalassaemia major male individual was transfusion-dependent and had an atypical β-globin gene cluster haplotype. Of the tw...

journal_title：Genetics and molecular biology

authors： Moosa MM,Ayub MI,Bashar AE,Sarwardi G,Khan W,Khan H,Yeasmin S

更新日期：2011-07-01 00:00:00

abstract：:Lupinus albescens is a resistant cover plant that establishes symbiotic relationships with bacteria belonging to the Bradyrhizobium genus. This symbiosis helps the development of these plants in adverse environmental conditions, such as the ones found in arenized areas of Southern Brazil. This work studied three Brady...

journal_title：Genetics and molecular biology

authors： Granada CE,Vargas LK,Sant'Anna FH,Balsanelli E,Baura VA,Oliveira Pedrosa F,Souza EM,Falcon T,Passaglia LMP

更新日期：2018-04-01 00:00:00

abstract：:Despite their ecological and economical importance, fishes of the family Ariidae are still genetically and cytogenetically poorly studied. Among the 133 known species of ariids, only eight have been karyotyped. Cytogenetic analyses performed on Genidens barbus and Sciades herzbergii revealed that both species have 2n ...

journal_title：Genetics and molecular biology

authors： Nirchio M,Martinez ER,Foresti F,Oliveira C

更新日期：2010-04-01 00:00:00

abstract：:The purpose of this study was to investigate whether treatment with electroacupuncture (EA) inhibited mitochondria-dependent apoptosis in annulus fibrosis (AF) cells in a rat model of cervical intervertebral disc degradation induced by unbalanced dynamic and static forces. Forty Sprague-Dawley rats were used in this s...

journal_title：Genetics and molecular biology

authors： Liao J,Ke M,Xu T,Lin L

更新日期：2012-07-01 00:00:00

abstract：:More than 90% of birds are socially monogamous, although genetic studies indicate that many are often not sexually monogamous. In the present study, DNA fingerprinting was used to estimate the genetic relationships between nestlings belonging to the same broods to evaluate the mating system in the socially monogamous ...

journal_title：Genetics and molecular biology

authors： Caparroz R,Miyaki CY,Baker AJ

更新日期：2011-01-01 00:00:00

abstract：:This study aimed to use gene chips to investigate differential gene expression profiles in the occurrence and development of acute myocardial infarction (AMI). The study included 12 AMI patients and 12 healthy individuals. Total mRNA of peripheral bloodwas extracted and reversed-transcribed to cDNA for microarray anal...

journal_title：Genetics and molecular biology

authors： Fan L,Meng H,Guo X,Li X,Meng F

更新日期：2018-01-01 00:00:00

abstract：:B chromosomes are supernumerary elements present in about 15% of eukaryotic species and are most frequently heterochromatic, behave parasitically, show a transmission rate higher than standard (A) chromosomes, and can provoke harmful effects on carriers. In the current work, Prochilodus lineatus individuals carrying e...

journal_title：Genetics and molecular biology

authors： Voltolin TA,Senhorini JA,Foresti F,Bortolozzi J,Porto-Foresti F

更新日期：2011-04-01 00:00:00

abstract：:The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populations all over the wor...

journal_title：Genetics and molecular biology

authors： Boldt AB,Culpi L,Tsuneto LT,Souza IR,Kun JF,Petzl-Erler ML

更新日期：2009-01-01 00:00:00

abstract：:In this study, we investigated the influence of two SNPs (rs846910 and rs12086634) of the HSD11B1 gene that encodes 11β-hydroxysteroid dehydrogenase type 1(11β-HSD1), the enzyme that catalyzes the conversion of cortisol to cortisone, on variables associated with obesity and metabolic syndrome in 215 individuals of bot...

journal_title：Genetics and molecular biology

authors： Turek LV,Leite N,Rodrigues Souza RL,Lima JK,Milano GE,Timossi Lda S,Osiecki AC,Osiecki R,Alle LF

更新日期：2014-09-01 00:00:00

abstract：:For a study of diversity and genetic structuring in Melipona quadrifasciata, 61 colonies were collected in eight locations in the state of Minas Gerais, Brazil. By means of PCR analysis, 119 ISSR bands were obtained, 80 (68%) being polymorphic. H(e) and H (B) were 0.20 and 0.16, respectively. Two large groups were obt...

journal_title：Genetics and molecular biology

authors： Nascimento MA,Batalha-Filho H,Waldschmidt AM,Tavares MG,Campos LA,Salomão TM

更新日期：2010-04-01 00:00:00

abstract：:Tobacco farmers are routinely exposed to complex mixtures of inorganic and organic chemicals present in tobacco leaves. In this study, we examined the genotoxicity of tobacco leaves in the snail Helix aspersa as a measure of the risk to human health. DNA damage was evaluated using the micronucleus test and the Comet a...

journal_title：Genetics and molecular biology

authors： da Silva FR,Erdtmann B,Dalpiaz T,Nunes E,Ferraz A,Martins TL,Dias JF,da Rosa DP,Porawskie M,Bona S,da Silva J

更新日期：2013-07-01 00:00:00

abstract：:Exercise is a double-edged sword: when practiced in moderation, it increases the expression of antioxidant enzymes, but when practiced strenuously it causes oxidative stress and cell damage. In this context, polymorphisms in the interleukin (IL)-6 gene should be investigated better because they can influence performan...

journal_title：Genetics and molecular biology

authors： Miranda-Vilela AL,Ribeiro IF,Grisolia CK

更新日期：2016-10-01 00:00:00

abstract：:We determined the polymorphism C242T of the aromatase gene (Cyp19) and its allelic frequency, as well as the effect of the variants on productive and reproductive traits in 71 purebred Santa Inês sheep, 13 purebred Brazilian Somali sheep, nine purebred Poll Dorset sheep, and 18 crossbred 1/2 Dorper sheep. The animals ...

journal_title：Genetics and molecular biology

authors： Lôbo AM,Lôbo RN,Paiva SR

更新日期：2009-07-01 00:00:00

abstract：:Catalase (CAT) is a common antioxidant enzyme in almost all living organisms. Currently, detailed reports on cucumber (Cucumis sativus L.) CAT (CsCAT) genes and tissue expression profiling are limited. In the present study, four candidate CsCAT genes were identified in cucumber. Phylogenetic analysis indicated that Cs...

journal_title：Genetics and molecular biology

authors： Hu L,Yang Y,Jiang L,Liu S

更新日期：2016-07-01 00:00:00

abstract：:Rhagomys rufescens (Rodentia: Sigmodontinae) is an endemic species of the Atlantic forest from Southern and Southeastern Brazil. Some authors consider Rhagomys as part of the tribe Thomasomyini; but its phylogenetic relationships remain unclear. Chromosomal studies on eight specimens of Rhagomys rufescens revealed a d...

journal_title：Genetics and molecular biology

authors： Testoni AF,Althoff SL,Nascimento AP,Steiner-Souza F,Sbalqueiro IJ

更新日期：2010-07-01 00:00:00