Genetic diversity of Morato's Digger Toad, Proceratophrys moratoi: spatial structure, gene flow, effective size and the need for differential management strategies of populations.

abstract：:Despite their ecological and economical importance, fishes of the family Ariidae are still genetically and cytogenetically poorly studied. Among the 133 known species of ariids, only eight have been karyotyped. Cytogenetic analyses performed on Genidens barbus and Sciades herzbergii revealed that both species have 2n ...

journal_title：Genetics and molecular biology

authors： Nirchio M,Martinez ER,Foresti F,Oliveira C

更新日期：2010-04-01 00:00:00

abstract：:Up-regulation of human endogenous retroviruses (HERVs) is associated with many diseases, including cancer. In this study, an H family HERV (HERV-H)-related gene was identified and characterized. Its spliced transcript lacks protein-coding capacity and may belong to the emerging class of noncoding RNAs (ncRNAs). The 1....

journal_title：Genetics and molecular biology

authors： Liang Q,Ding J,Zheng S

更新日期：2009-10-01 00:00:00

abstract：:We determined the polymorphism C242T of the aromatase gene (Cyp19) and its allelic frequency, as well as the effect of the variants on productive and reproductive traits in 71 purebred Santa Inês sheep, 13 purebred Brazilian Somali sheep, nine purebred Poll Dorset sheep, and 18 crossbred 1/2 Dorper sheep. The animals ...

journal_title：Genetics and molecular biology

authors： Lôbo AM,Lôbo RN,Paiva SR

更新日期：2009-07-01 00:00:00

abstract：:A detailed study of putative recombination events and their evolution frequency in the whole genome of the currently known members of the family Tombusviridae, comprising 79 accessions retrieved from the international databases, was carried out by using the RECCO and RDP version 3.31β algorithms. The first program all...

journal_title：Genetics and molecular biology

authors： Boulila M

更新日期：2011-10-01 00:00:00

abstract：:Phenotypic plasticity is a hallmark of the caste systems of social insects, expressed in their life history and morphological traits. These are best studied in bees. In their co-evolution with angiosperm plants, the females of corbiculate bees have acquired a specialized structure on their hind legs for collecting pol...

journal_title：Genetics and molecular biology

authors： Santos CG,Hartfelder K

更新日期：2015-07-01 00:00:00

abstract：:The order Anguilliformes comprises 15 families, 141 genera and 791 fish species. Eight families had at least one karyotyped species, with a prevalence of 2n = 38 chromosomes and high fundamental numbers (FN). The only exception to this pattern is the family Muraenidae, in which the eight species analyzed presented 2n ...

journal_title：Genetics and molecular biology

authors： Vasconcelos AJ,Molina WF

更新日期：2009-01-01 00:00:00

abstract：:Exercise is a double-edged sword: when practiced in moderation, it increases the expression of antioxidant enzymes, but when practiced strenuously it causes oxidative stress and cell damage. In this context, polymorphisms in the interleukin (IL)-6 gene should be investigated better because they can influence performan...

journal_title：Genetics and molecular biology

authors： Miranda-Vilela AL,Ribeiro IF,Grisolia CK

更新日期：2016-10-01 00:00:00

abstract：:Peanut (Arachis hypogaea) is the fifth most produced oil crop worldwide. Besides lack of water, fungal diseases are the most limiting factors for the crop. Several species of Arachis are resistant to certain pests and diseases. This study aimed to successfully cross the A-genome with B-K-A genome wild species previous...

journal_title：Genetics and molecular biology

authors： Fávero AP,Dos Santos RF,Simpson CE,Valls JF,Vello NA

更新日期：2015-07-01 00:00:00

abstract：:Machado-Joseph disease (MJD) is an autosomal dominant, late-onset neurological disorder and the most common form of spinocerebellar ataxia (SCA) worldwide. Diagnostic genetic testing is available to detect the disease-causing mutation by direct sizing of the CAG repeat tract in the ataxin 3 gene. Presymptomatic testin...

journal_title：Genetics and molecular biology

authors： Schuler-Faccini L,Osorio CM,Romariz F,Paneque M,Sequeiros J,Jardim LB

更新日期：2014-03-01 00:00:00

abstract：:Breast cancer (BC) is the most prevalent type worldwide, besides being one of the most common causes of death among women. It has been suggested that sporadic BC is most likely caused by low-penetrance genes, including those involved in DNA repair mechanisms. Furthermore, the accumulation of DNA damage may contribute ...

journal_title：Genetics and molecular biology

authors： Santos RA,Teixeira AC,Mayorano MB,Carrara HH,Andrade JM,Takahashi CS

更新日期：2010-10-01 00:00:00

abstract：:Cannabinoids, flavonoids, and stilbenoids have been identified in the annual dioecious plant Cannabis sativa L. Of these, the cannabinoids are the best known group of this plant's natural products. Polyketide synthases (PKSs) are responsible for the biosynthesis of diverse secondary metabolites, including flavonoids a...

journal_title：Genetics and molecular biology

authors： Flores-Sanchez IJ,Linthorst HJ,Verpoorte R

更新日期：2010-10-01 00:00:00

abstract：:Birth defects (BDs) are functional and structural alterations in embryonic or fetal development. With an incidence of approximately 3-5%, BDs are a leading cause of infant mortality and lifelong disability. A population-based prospective case-control study was conducted for one year with 5204 infants, between March 1s...

journal_title：Genetics and molecular biology

authors： Oliveira-Brancati CIF,Ferrarese VCC,Costa AR,Fett-Conte AC

更新日期：2020-02-10 00:00:00

abstract：:Tissue samples from mosquitoes artificially infected with Zika virus and shown to be positive by RT-qPCR were reexamined by RT-PCR. Using these samples we compared the two methods employed in virus RNA detection for vector competence studies. Results demonstrated that, albeit useful, RT-PCR gave false negatives with l...

journal_title：Genetics and molecular biology

authors： Paiva MHS,Guedes DRD,Leal WS,Ayres CFJ

更新日期：2017-07-01 00:00:00

abstract：:Sickle cell anemia is a genetic disease with high prevalence in people of African descent. There are five typical haplotypes associated with this disease and the haplotypes associated with the beta-globin gene cluster have been used to establish the origin of African-descendant people in America. In this work, we dete...

journal_title：Genetics and molecular biology

authors： Fong C,Lizarralde-Iragorri MA,Rojas-Gallardo D,Barreto G

更新日期：2013-12-01 00:00:00

abstract：:Topoisomerase II inhibitors are effective chemotherapeutic agents in the treatment of cancer, in spite of being associated with the development of secondary leukemia. Our purpose was to determine the effects of etoposide on different genomic regions, aiming at discovering whether there are preferential sites which can...

journal_title：Genetics and molecular biology

authors： Brassesco MS,Montaldi AP,Sakamoto-Hojo ET

更新日期：2009-01-01 00:00:00

abstract：:Meiotic and mitotic chromosomes of Dichotomius nisus, D. semisquamosus and D. sericeus were analyzed after conventional staining, C-banding and silver nitrate staining. In addition, Dichotomius nisus and D. semisquamosus chromosomes were also analyzed after fluorescent in situ hybridization (FISH) with an rDNA probe. ...

journal_title：Genetics and molecular biology

authors： da Silva GM,Bione EG,Cabral-de-Mello DC,de Moura Rde C,Simões ZL,de Souza MJ

更新日期：2009-04-01 00:00:00

abstract：:Xylella fastidiosa genome sequencing has generated valuable data by identifying genes acting either on metabolic pathways or in associated pathogenicity and virulence. Based on available information on these genes, new strategies for studying their expression patterns, such as microarray technology, were employed. A t...

journal_title：Genetics and molecular biology

authors： Travensolo RF,Carareto-Alves LM,Costa MV,Lopes TJ,Carrilho E,Lemos EG

更新日期：2009-04-01 00:00:00

abstract：:Oral Lichen Planus (OLP) is an oral inflammatory condition, mediated by host immune system reaction, presenting basal membrane damages with inflammatory lesions in the mouth and/or skin. In this study, the role of functional polymorphisms in the MBL2 gene, encoding for Mannose-Binding Protein C (MBP-C), a member of th...

journal_title：Genetics and molecular biology

authors： Polesello V,Segat L,Biasotto M,Ottaviani G,Gobbo M,Di Lenarda R,Crovella S,Zupin L

更新日期：2019-01-01 00:00:00

abstract：:4-Coumaric acid: coenzyme A ligase (4CL) is a key enzyme in the phenylpropanoid metabolic pathway that regulates the biosynthesis of lignin and flavonoids. Therefore, the study of 4CL is important to explore the accumulation and regulation of metabolites. This study investigated the role that the 4CL2 gene from Dryopt...

journal_title：Genetics and molecular biology

authors： Li SS,Chang Y,Li B,Shao SL,Zhen-Zhu- Z

更新日期：2020-05-20 00:00:00

abstract：:Trypoxylon is a genus of solitary crabronid wasps whose population genetics is poorly known. The purpose of the present study was to investigate the genetic variation and differentiation among five populations of Trypoxylon albitarse, a species widely distributed throughout the Neotropics, with records from Panama to ...

journal_title：Genetics and molecular biology

authors： Bergamaschi AC,Lama MA

更新日期：2015-12-01 00:00:00

abstract：:Lupinus albescens is a resistant cover plant that establishes symbiotic relationships with bacteria belonging to the Bradyrhizobium genus. This symbiosis helps the development of these plants in adverse environmental conditions, such as the ones found in arenized areas of Southern Brazil. This work studied three Brady...

journal_title：Genetics and molecular biology

authors： Granada CE,Vargas LK,Sant'Anna FH,Balsanelli E,Baura VA,Oliveira Pedrosa F,Souza EM,Falcon T,Passaglia LMP

更新日期：2018-04-01 00:00:00

abstract：:The PPARγ nuclear receptor regulates the expression of genes involved in lipid and carbohydrate metabolism, and it has protective effects in some patients with type 2 diabetes. Nevertheless, the therapeutic value of the PPARγ nuclear receptor protein is limited due to the secondary effects of some PPARγ ligands. Becau...

journal_title：Genetics and molecular biology

authors： Lizcano F,Vargas D

更新日期：2013-03-01 00:00:00

abstract：:In order to understand the genetic ancestry and mitochondrial DNA (mtDNA) diversity of current Colombian horse breeds we sequenced a 364-bp fragment of the mitocondrial DNA D-loop in 116 animals belonging to five Spanish horse breeds and the Colombian Paso Fino and Colombian Creole cattle horse breeds. Among Colombian...

journal_title：Genetics and molecular biology

authors： Jimenez LM,Mendez S,Dunner S,Cañón J,Cortés O

更新日期：2012-12-01 00:00:00

abstract：:Jatropha gossypiifolia L. (Euphorbiaceae), popularly known as cotton-leaf physicnut, is a milky shrub notable for its medicinal properties. The present study aimed to evaluate the toxic, cytotoxic and genotoxic effects of the latex of J. gossypiifolia, using Allium cepa L. as test system. Seeds of A. cepa were exposed...

journal_title：Genetics and molecular biology

authors： de Almeida PM,de Sousa Araújo S,Marin-Morales MA,Benko-Iseppon AM,Brasileiro-Vidal AC

更新日期：2015-03-01 00:00:00

abstract：:Molecular genetic research relies heavily on the ability to detect polymorphisms in DNA. Single nucleotide polymorphisms (SNPs) are the most frequent form of DNA variation in the genome. In combination with a PCR assay, the corresponding SNP can be analyzed as a derived cleaved amplified polymorphic sequence (dCAPS) m...

journal_title：Genetics and molecular biology

authors： Shahinnia F,Sayed-Tabatabaei BE

更新日期：2009-07-01 00:00:00

abstract：:Rabies is a fatal zoonotic infection of the central nervous system of mammals and has been known to humans for millennia. The etiological agent, is a neurotropic RNA virus in the order Mononegavirales, family Rhabdoviridae, genus Lyssavirus. There are currently accepted to be two cycles for rabies transmission: the ur...

journal_title：Genetics and molecular biology

authors： Oliveira RN,Freire CC,Iamarino A,Zanotto PM,Pessoa R,Sanabani SS,Souza SP,Castilho JG,Batista HBCR,Carnieli P Jr,Macedo CI,Watanabe JT,Brandão PE

更新日期：2020-07-31 00:00:00

abstract：:We genotyped 15 microsatellite loci in order to evaluate the effects of habitat fragmentation, caused by flooding of the Tucuruí reservoir, on the genetic structure of Alouatta belzebul in eastern Amazonia. The analysis included two populations sampled in 1984, representing both margins of the Tocantins river, and thr...

journal_title：Genetics and molecular biology

authors： Bastos HB,Gonçalves EC,Ferrari SF,Silva A,Schneider MP

更新日期：2010-10-01 00:00:00

abstract：:Blood methylated cell-free DNA (cfDNA) as a minimally invasive cancer biomarker has great importance in cancer management. Guanylate binding protein 2 (GBP2) has been considered as a possible controlling factor in tumor development. GBP2 gene expression and its promoter methylation status in both plasma cfDNA and tumo...

journal_title：Genetics and molecular biology

authors： Rahvar F,Salimi M,Mozdarani H

更新日期：2020-11-17 00:00:00

abstract：:Oryza sativa, the common cultivated rice, is one of the most important crops for human consumption, but production is increasingly threatened by abiotic stresses. Although many efforts have resulted in breeding rice cultivars that are relatively tolerant to their local environments, climate changes and population incr...

journal_title：Genetics and molecular biology

authors： Menguer PK,Sperotto RA,Ricachenevsky FK

更新日期：2017-01-01 00:00:00

abstract：:Genetic variation was estimated in ten samples populations of Aedes aegypti from the Brazilian Amazon, by using a 380 bp fragment of the mitochocondrial NADH dehydrogenase subunit 4 (ND4) gene. A total of 123 individuals were analyzed, whereby 13 haplotypes were found. Mean genetic diversity was slightly high (h = 0.6...

journal_title：Genetics and molecular biology

authors： Lima RS Jr,Scarpassa VM

更新日期：2009-04-01 00:00:00