Aromatase gene and its effects on growth, reproductive and maternal ability traits in a multibreed sheep population from Brazil.

abstract：:Oral Lichen Planus (OLP) is an oral inflammatory condition, mediated by host immune system reaction, presenting basal membrane damages with inflammatory lesions in the mouth and/or skin. In this study, the role of functional polymorphisms in the MBL2 gene, encoding for Mannose-Binding Protein C (MBP-C), a member of th...

journal_title：Genetics and molecular biology

authors： Polesello V,Segat L,Biasotto M,Ottaviani G,Gobbo M,Di Lenarda R,Crovella S,Zupin L

更新日期：2019-01-01 00:00:00

abstract：:Peanut (Arachis hypogaea) is the fifth most produced oil crop worldwide. Besides lack of water, fungal diseases are the most limiting factors for the crop. Several species of Arachis are resistant to certain pests and diseases. This study aimed to successfully cross the A-genome with B-K-A genome wild species previous...

journal_title：Genetics and molecular biology

authors： Fávero AP,Dos Santos RF,Simpson CE,Valls JF,Vello NA

更新日期：2015-07-01 00:00:00

abstract：:The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populations all over the wor...

journal_title：Genetics and molecular biology

authors： Boldt AB,Culpi L,Tsuneto LT,Souza IR,Kun JF,Petzl-Erler ML

更新日期：2009-01-01 00:00:00

abstract：:Since around 1723, on the occasion of its initial colonization by Europeans, Rondonia has received successive waves of immigrants. This has been further swelled by individuals from northeastern Brazil, who began entering at the beginning of the twentieth century. The ethnic composition varies across the state accordin...

journal_title：Genetics and molecular biology

authors： de Farias JD,Santos MG,de França AK,Delani D,Tada MS,Casseb AA,Simões AL,Engracia V

更新日期：2012-01-01 00:00:00

abstract：:A wide array of molecular markers has been used to investigate the genetic diversity among common bean species. However, the best combination of markers for studying such diversity among common bean cultivars has yet to be determined. Few reports have examined the genetic diversity of the carioca bean, commercially on...

journal_title：Genetics and molecular biology

authors： Küpper Cardoso Perseguini JM,Chioratto AF,Zucchi MI,Colombo CA,Carbonell SA,Costa Mondego JM,Gazaffi R,Franco Garcia AA,de Campos T,de Souza AP,Rubiano LB

更新日期：2011-01-01 00:00:00

abstract：:The roots of the understorey shrub Carapichea ipecacuanha (ipecac) have medicinal properties, and the uprooting of wild plants has supplied most of the world demand for this species. Although under severe population decline, C. ipecacuanha lacks legal protection. In the wild, the aerial stems of ipecac clump together ...

journal_title：Genetics and molecular biology

authors： de Oliveira LO,Venturini BA,Rossi AA,Hastenreiter SS

更新日期：2010-01-01 00:00:00

abstract：:Topoisomerase II inhibitors are effective chemotherapeutic agents in the treatment of cancer, in spite of being associated with the development of secondary leukemia. Our purpose was to determine the effects of etoposide on different genomic regions, aiming at discovering whether there are preferential sites which can...

journal_title：Genetics and molecular biology

authors： Brassesco MS,Montaldi AP,Sakamoto-Hojo ET

更新日期：2009-01-01 00:00:00

abstract：:Cytogenetic studies in birds are still scarce compared to other vertebrates. Woodcreepers (Dendrocolaptidae) are part of a highly specialized group within the Suboscines of the New World. They are forest birds exclusive to the Neotropical region and similar to woodpeckers, at a comparable evolutionary stage. This pape...

journal_title：Genetics and molecular biology

authors： de Oliveira Barbosa M,da Silva RR,de Sena Correia VC,Dos Santos LP,Garnero Adel V,Gunski RJ

更新日期：2013-03-01 00:00:00

abstract：:The Latin American School of Human and Medical Genetics (ELAG) is the main course of its kind in the genetics field in Latin America. Here we describe the main challenges regarding the organization of such event, including how we obtain funding and how we proceed with student selection. Thus, we aim to share our exper...

journal_title：Genetics and molecular biology

authors： Vairo F,López ML,Cruz CU,Corrêa PG,Baldo G

更新日期：2014-03-01 00:00:00

abstract：:Now a days, an important and interesting alternative in the control of tick-infestation in cattle is to select resistant animals, and identify the respective quantitative trait loci (QTLs) and DNA markers, for posterior use in breeding programs. The number of ticks/animal is characterized as a discrete-counting trait,...

journal_title：Genetics and molecular biology

authors： Silva FF,Tunin KP,Rosa GJ,da Silva MV,Azevedo AL,da Silva Verneque R,Machado MA,Packer IU

更新日期：2011-10-01 00:00:00

abstract：:The decapod Grapsus grapsus is commonly found on oceanic islands of the Pacific and Atlantic coasts of the Americas. In this study, a simple, quick and reliable method for detecting its larvae in plankton samples is described, which makes it ideal for large-scale studies of larval dispersal patterns in the species. ...

journal_title：Genetics and molecular biology

authors： Ströher PR,Firkowski CR,Freire AS,Pie MR

更新日期：2011-07-01 00:00:00

abstract：:Switchgrass (Panicum virgatum L.; family Poaceae) is a warm-season C4 perennial grass. Tillering plays an important role in determining the morphology of aboveground parts and the final biomass yield of switchgrass. Auxin distribution in plants can affect a variety of important growth and developmental processes, incl...

journal_title：Genetics and molecular biology

authors： Xu K,Sun F,Wang Y,Shi L,Liu S,Xi Y

更新日期：2016-03-01 00:00:00

abstract：:Tissue samples from mosquitoes artificially infected with Zika virus and shown to be positive by RT-qPCR were reexamined by RT-PCR. Using these samples we compared the two methods employed in virus RNA detection for vector competence studies. Results demonstrated that, albeit useful, RT-PCR gave false negatives with l...

journal_title：Genetics and molecular biology

authors： Paiva MHS,Guedes DRD,Leal WS,Ayres CFJ

更新日期：2017-07-01 00:00:00

abstract：:Population genetics studies the distributions and changes in population allele frequencies in response to processes, such as mutation, natural selection, gene flow, and genetic drift. Researchers daily manage genetic, biological, and environmental data of the samples, storing them in text files or spreadsheets, which ...

journal_title：Genetics and molecular biology

authors： Elias DE,Rueda ECR

更新日期：2020-05-29 00:00:00

abstract：:Treatment of moderate and severe forms of osteogenesis imperfecta (OI) with cyclic pamidronate at the Reference Center for OI Treatment in Southern Brazil was studied. A retrospective cohort study was conducted from 2002 to 2012. Data were obtained during inpatient (drug infusion) and outpatient care. Clinical data, i...

journal_title：Genetics and molecular biology

authors： Pinheiro B,Zambrano MB,Vanz AP,Brizola E,Souza LT,Félix TM

更新日期：2019-01-01 00:00:00

abstract：:Heat shock (HS) leads to the activation of molecular mechanisms, known as HS-response, that prevent damage and enhance survival under stress. Plants have a flexible and specialized network of Heat Shock Factors (HSFs), which are transcription factors that induce the expression of heat shock proteins. The present work ...

journal_title：Genetics and molecular biology

authors： Soares-Cavalcanti NM,Belarmino LC,Kido EA,Pandolfi V,Marcelino-Guimarães FC,Rodrigues FA,Pereira GA,Benko-Iseppon AM

更新日期：2012-06-01 00:00:00

abstract：:The purpose of this study was to investigate whether treatment with electroacupuncture (EA) inhibited mitochondria-dependent apoptosis in annulus fibrosis (AF) cells in a rat model of cervical intervertebral disc degradation induced by unbalanced dynamic and static forces. Forty Sprague-Dawley rats were used in this s...

journal_title：Genetics and molecular biology

authors： Liao J,Ke M,Xu T,Lin L

更新日期：2012-07-01 00:00:00

abstract：:Phylogenetic species of Paracoccidioides brasiliensis complex (S1a and S1b, PS2, PS3, and PS4) and Paracoccidioides lutzii are agents of paracoccidioidomycosis, an endemic fungal disease in Latin America. P. restrepiensis (PS3 genotype) was classified as monophyletic and geographically restricted to Colombia and neigh...

journal_title：Genetics and molecular biology

authors： Cocio TA,Nascimento E,Kress MRVZ,Bagagli E,Martinez R

更新日期：2020-05-29 00:00:00

abstract：:The aim of this study was to evaluate the impact and mechanism of co-blocking of costimulatory signals CD28-B7-CD40-CD40L during immune allograft rejection. Forty-eight recipient rabbits were prepared as a high-risk corneal allograft model. After surgery, the animals were randomly divided into: control group, MR1 grou...

journal_title：Genetics and molecular biology

authors： Zhao HX,Li XY,Guan WY,Han XT

更新日期：2019-04-01 00:00:00

abstract：:A detailed study of putative recombination events and their evolution frequency in the whole genome of the currently known members of the family Tombusviridae, comprising 79 accessions retrieved from the international databases, was carried out by using the RECCO and RDP version 3.31β algorithms. The first program all...

journal_title：Genetics and molecular biology

authors： Boulila M

更新日期：2011-10-01 00:00:00

abstract：:MicroRNAs are considered as potential biomarkers, agents, or therapeutic targets; few studies have addressed the expression of miRNAs in treatment-naïve patients infected with HIV-1. The aim of this study was to assess plasma relative circulating miRNA expression profiles in treatment-naïve Mexican patients with HIV/A...

journal_title：Genetics and molecular biology

authors： Cárdenas-Bedoya J,Marquez-Pedroza J,Morán-Moguel MC,Escoto-Delgadillo M,Vázquez-Valls E,González-Enríquez GV,Pérez-Ríos AM,Torres-Mendoza BM

更新日期：2020-06-22 00:00:00

abstract：:4-Coumaric acid: coenzyme A ligase (4CL) is a key enzyme in the phenylpropanoid metabolic pathway that regulates the biosynthesis of lignin and flavonoids. Therefore, the study of 4CL is important to explore the accumulation and regulation of metabolites. This study investigated the role that the 4CL2 gene from Dryopt...

journal_title：Genetics and molecular biology

authors： Li SS,Chang Y,Li B,Shao SL,Zhen-Zhu- Z

更新日期：2020-05-20 00:00:00

abstract：:B chromosomes are supernumerary elements present in about 15% of eukaryotic species and are most frequently heterochromatic, behave parasitically, show a transmission rate higher than standard (A) chromosomes, and can provoke harmful effects on carriers. In the current work, Prochilodus lineatus individuals carrying e...

journal_title：Genetics and molecular biology

authors： Voltolin TA,Senhorini JA,Foresti F,Bortolozzi J,Porto-Foresti F

更新日期：2011-04-01 00:00:00

abstract：:In order to understand the genetic ancestry and mitochondrial DNA (mtDNA) diversity of current Colombian horse breeds we sequenced a 364-bp fragment of the mitocondrial DNA D-loop in 116 animals belonging to five Spanish horse breeds and the Colombian Paso Fino and Colombian Creole cattle horse breeds. Among Colombian...

journal_title：Genetics and molecular biology

authors： Jimenez LM,Mendez S,Dunner S,Cañón J,Cortés O

更新日期：2012-12-01 00:00:00

abstract：:Jatropha gossypiifolia L. (Euphorbiaceae), popularly known as cotton-leaf physicnut, is a milky shrub notable for its medicinal properties. The present study aimed to evaluate the toxic, cytotoxic and genotoxic effects of the latex of J. gossypiifolia, using Allium cepa L. as test system. Seeds of A. cepa were exposed...

journal_title：Genetics and molecular biology

authors： de Almeida PM,de Sousa Araújo S,Marin-Morales MA,Benko-Iseppon AM,Brasileiro-Vidal AC

更新日期：2015-03-01 00:00:00

abstract：:The PPARγ nuclear receptor regulates the expression of genes involved in lipid and carbohydrate metabolism, and it has protective effects in some patients with type 2 diabetes. Nevertheless, the therapeutic value of the PPARγ nuclear receptor protein is limited due to the secondary effects of some PPARγ ligands. Becau...

journal_title：Genetics and molecular biology

authors： Lizcano F,Vargas D

更新日期：2013-03-01 00:00:00

abstract：:Blood methylated cell-free DNA (cfDNA) as a minimally invasive cancer biomarker has great importance in cancer management. Guanylate binding protein 2 (GBP2) has been considered as a possible controlling factor in tumor development. GBP2 gene expression and its promoter methylation status in both plasma cfDNA and tumo...

journal_title：Genetics and molecular biology

authors： Rahvar F,Salimi M,Mozdarani H

更新日期：2020-11-17 00:00:00

abstract：:Cannabinoids, flavonoids, and stilbenoids have been identified in the annual dioecious plant Cannabis sativa L. Of these, the cannabinoids are the best known group of this plant's natural products. Polyketide synthases (PKSs) are responsible for the biosynthesis of diverse secondary metabolites, including flavonoids a...

journal_title：Genetics and molecular biology

authors： Flores-Sanchez IJ,Linthorst HJ,Verpoorte R

更新日期：2010-10-01 00:00:00

abstract：:The antitumorigenic potential of two palladium(II) complexes, [Pd(ca(2)-o-phen)Cl(2)] - C1 and [Pd(dmba)(dppp)Cl] - C2, was evaluated, using MDA-MB-435 cells, a human breast adenocarcinoma cell-line that does not express the estrogen receptor α (ER-). Growth inhibition and induced alterations in cell-morphology were a...

journal_title：Genetics and molecular biology

authors： Campanella NC,da Silva Demartini M,Torres C,de Almeida ET,Gouvêa CM

更新日期：2012-01-01 00:00:00

abstract：:In this work we describe the establishment of mesenchymal stem cells (MSCs) derived from embryonic stem cells (ESCs) and the role of bFGF in adipocyte differentiation. The totipotency of ESCs and MSCs was assessed by immunofluorescence staining and RT-PCR of totipotency factors. MSCs were successfully used to induce o...

journal_title：Genetics and molecular biology

authors： Song X,Li Y,Chen X,Yin G,Huang Q,Chen Y,Xu G,Wang L

更新日期：2014-03-01 00:00:00