Abstract：
:The advent of Fluorescence Microscopy over the last few years have dramatically improved the problem of visualization and tracking of specific cellular objects for biological inference. But like any other imaging system, fluorescence microscopy has its own limitations. The resultant images suffer from the effect of noise due to both signal dependent and signal independent factors, thereby limiting the possibility of biological inferencing. Denoising is a class of image processing algorithms that aim to remove noise from acquired images and has gained wide attention in the field of fluorescence microscopy image restoration. In this paper, we propose an image denoising algorithm based on the concept of feature extraction through multifractal decomposition and then estimate a noise free image from the gradients restricted to these features. Experimental results over simulated and real fluorescence microscopy data prove the merit of the proposed approach, both visually and quantitatively.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Maji SK,Yahia Hdoi
10.1038/s41598-019-43973-2subject
Has Abstractpub_date
2019-05-22 00:00:00pages
7725issue
1issn
2045-2322pii
10.1038/s41598-019-43973-2journal_volume
9pub_type
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