Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method.

abstract：:The primary motor cortex has an important role in the precise execution of learned motor responses. During motor learning, synaptic efficacy between sensory and primary motor cortical neurons is enhanced, possibly involving long-term potentiation and N-methyl-D-aspartate (NMDA)-specific glutamate receptor function. To...

journal_title：Nature communications

authors： Hasan MT,Hernández-González S,Dogbevia G,Treviño M,Bertocchi I,Gruart A,Delgado-García JM

更新日期：2013-01-01 00:00:00

abstract：:Effective prevention strategies will be essential in reducing disease burden due to bacterial infections. Here we harness the specificity and rapid-acting properties of bacteriophages as a potential prophylaxis therapy for cholera, a severely dehydrating disease caused by Vibrio cholerae. To this end, we test a cockta...

journal_title：Nature communications

authors： Yen M,Cairns LS,Camilli A

更新日期：2017-02-01 00:00:00

abstract：:We report the results from the first 5D tomographic diffraction imaging experiment of a complex Ni-Pd/CeO2-ZrO2/Al2O3 catalyst used for methane reforming. This five-dimensional (three spatial, one scattering and one dimension to denote time/imposed state) approach enabled us to track the chemical evolution of many par...

journal_title：Nature communications

authors： Vamvakeros A,Jacques SDM,Di Michiel M,Matras D,Middelkoop V,Ismagilov IZ,Matus EV,Kuznetsov VV,Drnec J,Senecal P,Beale AM

更新日期：2018-11-12 00:00:00

abstract：:Insight into crumpling or compaction of one-dimensional objects is important for understanding biopolymer packaging and designing innovative technological devices. By compacting various types of wires in rigid confinements and characterizing the morphology of the resulting crumpled structures, here, we report how fric...

journal_title：Nature communications

authors： Shaebani MR,Najafi J,Farnudi A,Bonn D,Habibi M

更新日期：2017-06-06 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity, learning and memory, and are implicated in various neuronal disorders. We synthesized a diffusible photochromic glutamate analogue, azobenzene-triazole-glutamate (ATG), which is specific for NMDARs and functions as a photoswitchable ag...

journal_title：Nature communications

authors： Laprell L,Repak E,Franckevicius V,Hartrampf F,Terhag J,Hollmann M,Sumser M,Rebola N,DiGregorio DA,Trauner D

更新日期：2015-08-27 00:00:00

abstract：:Many small-interfering (si)RNAs are toxic to cancer cells through a 6mer seed sequence (positions 2-7 of the guide strand). Here we performed an siRNA screen with all 4096 6mer seeds revealing a preference for guanine in positions 1 and 2 and a high overall G or C content in the seed of the most toxic siRNAs for four ...

journal_title：Nature communications

authors： Gao QQ,Putzbach WE,Murmann AE,Chen S,Sarshad AA,Peter JM,Bartom ET,Hafner M,Peter ME

更新日期：2018-10-29 00:00:00

abstract：:A high-sugar diet has been associated with reduced lifespan in organisms ranging from worms to mammals. However, the mechanisms underlying the harmful effects of glucose are poorly understood. Here we establish a causative relationship between endogenous glucose storage in the form of glycogen, resistance to oxidative...

journal_title：Nature communications

authors： Gusarov I,Pani B,Gautier L,Smolentseva O,Eremina S,Shamovsky I,Katkova-Zhukotskaya O,Mironov A,Nudler E

更新日期：2017-06-19 00:00:00

abstract：:Bloch electrons lacking inversion symmetry exhibit orbital magnetic moments owing to the rotation around their center of mass; this moment induces a valley splitting in a magnetic field. For the graphene/h-BN moiré superlattice, inversion symmetry is broken by the h-BN. The superlattice potential generates a series of...

journal_title：Nature communications

authors： Moriya R,Kinoshita K,Crosse JA,Watanabe K,Taniguchi T,Masubuchi S,Moon P,Koshino M,Machida T

更新日期：2020-10-23 00:00:00

abstract：:In nature, protein subunits on the capsids of many icosahedral viruses form rotational patterns, and mathematicians also incorporate asymmetric patterns into faces of polyhedra. Chemists have constructed molecular polyhedra with vacant or highly symmetric faces, but very little is known about constructing polyhedra wi...

journal_title：Nature communications

authors： Wang X,Wang Y,Yang H,Fang H,Chen R,Sun Y,Zheng N,Tan K,Lu X,Tian Z,Cao X

更新日期：2016-08-24 00:00:00

abstract：:Acetic acid is an important bulk chemical that is currently produced via methanol carbonylation using fossil based CO. Synthesis of acetic acid from the renewable and cheap CO2 is of great importance, but state of the art routes encounter difficulties, especially in reaction selectivity and activity. Here we report a ...

journal_title：Nature communications

authors： Qian Q,Zhang J,Cui M,Han B

更新日期：2016-05-11 00:00:00

abstract：:How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. The intermediate immune infiltration cluster (Cluster B) is associated ...

journal_title：Nature communications

authors： Tekpli X,Lien T,Røssevold AH,Nebdal D,Borgen E,Ohnstad HO,Kyte JA,Vallon-Christersson J,Fongaard M,Due EU,Svartdal LG,Sveli MAT,Garred Ø,OSBREAC.,Frigessi A,Sahlberg KK,Sørlie T,Russnes HG,Naume B,Kristensen VN

更新日期：2019-12-03 00:00:00

abstract：:Modelling of non-adiabatic dynamics in extended molecular systems and solids is a next frontier of atomistic electronic structure theory. The underlying numerical algorithms should operate only with a few quantities (that can be efficiently obtained from quantum chemistry), provide a controlled approximation (which ca...

journal_title：Nature communications

authors： Gorshkov VN,Tretiak S,Mozyrsky D

更新日期：2013-01-01 00:00:00

abstract：:The insulator-to-metal transition continues to be a challenging subject, especially when electronic correlations are strong. In layered compounds, such as La2-xSrxNiO4 and La2-xBaxCuO4, the doped charge carriers can segregate into periodically spaced charge stripes separating narrow domains of antiferromagnetic order....

journal_title：Nature communications

authors： Anissimova S,Parshall D,Gu GD,Marty K,Lumsden MD,Chi S,Fernandez-Baca JA,Abernathy DL,Lamago D,Tranquada JM,Reznik D

更新日期：2014-03-17 00:00:00

abstract：:The competition between bimolecular nucleophilic substitution and base-induced elimination is of fundamental importance for the synthesis of pure samples in organic chemistry. Many factors that influence this competition have been identified over the years, but the underlying atomistic dynamics have remained difficult...

journal_title：Nature communications

authors： Carrascosa E,Meyer J,Zhang J,Stei M,Michaelsen T,Hase WL,Yang L,Wester R

更新日期：2017-06-21 00:00:00

abstract：:Hybrid quantum systems are essential for the realization of distributed quantum networks. In particular, piezo-mechanics operating at typical superconducting qubit frequencies features low thermal excitations, and offers an appealing platform to bridge superconducting quantum processors and optical telecommunication c...

journal_title：Nature communications

authors： Han X,Fu W,Zhong C,Zou CL,Xu Y,Sayem AA,Xu M,Wang S,Cheng R,Jiang L,Tang HX

更新日期：2020-06-26 00:00:00

abstract：:Quantum fluctuations give rise to van der Waals and Casimir forces that dominate the interaction between electrically neutral objects at sub-micron separations. Under the trend of miniaturization, such quantum electrodynamical effects are expected to play an important role in micro- and nano-mechanical devices. Nevert...

journal_title：Nature communications

authors： Zou J,Marcet Z,Rodriguez AW,Reid MT,McCauley AP,Kravchenko II,Lu T,Bao Y,Johnson SG,Chan HB

更新日期：2013-01-01 00:00:00

abstract：:Wilms tumor gene on the X chromosome (WTX) is a putative tumor suppressor gene in Wilms tumor, but its expression and functions in other tumors are unclear. Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in women and the second leading cause in men in the United States. We demonstrated tha...

journal_title：Nature communications

authors： Zhu GF,Xu YW,Li J,Niu HL,Ma WX,Xu J,Zhou PR,Liu X,Ye DL,Liu XR,Yan T,Zhai WK,Xu ZJ,Liu C,Wang L,Wang H,Luo JM,Liu L,Li XQ,Guo S,Jiang HP,Shen P,Lin HK,Yu DH,Ding YQ,Zhang QL

更新日期：2019-01-10 00:00:00

abstract：:The original version of this Article contained an error in the last sentence of the second paragraph of the 'Atmospheric rarefaction effects' section of the Results, which incorrectly read 'The other one emulates the rarefied, CO2-rich Martian atmosphere (μ♂ = 1.3 × 10-5 N s m-2) at 6.9 mbar and 210 K, which gives ρ♂ ...

journal_title：Nature communications

authors： Di Renzo M,Urzay J

更新日期：2018-05-21 00:00:00

abstract：:In adult skin epidermis and the epithelium lining the esophagus cells are constantly shed from the tissue surface and replaced by cell division. Tracking genetically labelled cells in transgenic mice has given insight into cell behavior, but conflicting models appear consistent with the results. Here, we use an additi...

journal_title：Nature communications

authors： Piedrafita G,Kostiou V,Wabik A,Colom B,Fernandez-Antoran D,Herms A,Murai K,Hall BA,Jones PH

更新日期：2020-03-18 00:00:00

abstract：:Culture (behaviour based on socially transmitted information) is present in diverse animal species, yet how it interacts with genetic evolution remains largely unexplored. Here, we review the evidence for gene-culture coevolution in animals, especially birds, cetaceans and primates. We describe how culture can relax o...

journal_title：Nature communications

authors： Whitehead H,Laland KN,Rendell L,Thorogood R,Whiten A

更新日期：2019-06-03 00:00:00

abstract：:Individual cells in clonal populations often respond differently to environmental changes; for binary phenotypes, such as cell death, this can be measured as a fractional response. These types of responses have been attributed to cell-intrinsic stochastic processes and variable abundances of biochemical constituents, ...

journal_title：Nature communications

authors： Santos LC,Vogel R,Chipuk JE,Birtwistle MR,Stolovitzky G,Meyer P

更新日期：2019-03-21 00:00:00

abstract：:Analyzing scattered wave to recognize object is of fundamental significance in wave physics. Recently-emerged deep learning technique achieved great success in interpreting wave field such as in ultrasound non-destructive testing and disease diagnosis, but conventionally need time-consuming computer postprocessing or ...

journal_title：Nature communications

authors： Weng J,Ding Y,Hu C,Zhu XF,Liang B,Yang J,Cheng J

更新日期：2020-12-09 00:00:00

abstract：:Decoherence originates from the leakage of quantum information into external degrees of freedom. For a qubit, the two main decoherence channels are relaxation and dephasing. Here, we report an experiment on a superconducting qubit where we retrieve part of the lost information in both of these channels. We demonstrate...

journal_title：Nature communications

authors： Ficheux Q,Jezouin S,Leghtas Z,Huard B

更新日期：2018-05-15 00:00:00

abstract：:Previous studies have demonstrated that aneuploidy in human embryos is surprisingly frequent with 50-80% of cleavage-stage human embryos carrying an abnormal chromosome number. Here we combine non-invasive time-lapse imaging with karyotypic reconstruction of all blastomeres in four-cell human embryos to address the hy...

journal_title：Nature communications

authors： Chavez SL,Loewke KE,Han J,Moussavi F,Colls P,Munne S,Behr B,Reijo Pera RA

更新日期：2012-01-01 00:00:00

abstract：:A gene is considered essential if loss of function results in loss of viability, fitness or in disease. This concept is well established for coding genes; however, non-coding regions are thought less likely to be determinants of critical functions. Here we train a machine learning model using functional, mutational an...

journal_title：Nature communications

authors： Wells A,Heckerman D,Torkamani A,Yin L,Sebat J,Ren B,Telenti A,di Iulio J

更新日期：2019-11-20 00:00:00

abstract：:The ice- and organic-rich permafrost of the northeast Siberian Arctic lowlands (NESAL) has been projected to remain stable beyond 2100, even under pessimistic climate warming scenarios. However, the numerical models used for these projections lack processes which induce widespread landscape change termed thermokarst, ...

journal_title：Nature communications

authors： Nitzbon J,Westermann S,Langer M,Martin LCP,Strauss J,Laboor S,Boike J

更新日期：2020-05-04 00:00:00

abstract：:Biodiversity-ecosystem functioning (BEF) experiments have shown that local species richness promotes ecosystem functioning and stability. Whether this also applies under real-world conditions is still debated. Here, we focus on larger scales of space, time and ecological organization. We develop a quasi-experimental d...

journal_title：Nature communications

authors： Oehri J,Schmid B,Schaepman-Strub G,Niklaus PA

更新日期：2020-01-09 00:00:00

abstract：:Flexible organic memory devices are one of the integral components for future flexible organic electronics. However, high-density all-organic memory cell arrays on malleable substrates without cross-talk have not been demonstrated because of difficulties in their fabrication and relatively poor performances to date. H...

journal_title：Nature communications

authors： Ji Y,Zeigler DF,Lee DS,Choi H,Jen AK,Ko HC,Kim TW

更新日期：2013-01-01 00:00:00

abstract：:The future of coastal wetlands and their ecological value depend on their capacity to adapt to the interacting effects of human impacts and sea-level rise. Even though extensive wetland loss due to submergence is a possible scenario, its magnitude is highly uncertain due to limited understanding of hydrodynamic and bi...

journal_title：Nature communications

authors： Rodríguez JF,Saco PM,Sandi S,Saintilan N,Riccardi G

更新日期：2017-07-13 00:00:00

abstract：:Adenovirus is a nuclear replicating DNA virus reliant on host RNA processing machinery. Processing and metabolism of cellular RNAs can be regulated by METTL3, which catalyzes the addition of N6-methyladenosine (m6A) to mRNAs. While m6A-modified adenoviral RNAs have been previously detected, the location and function o...

journal_title：Nature communications

authors： Price AM,Hayer KE,McIntyre ABR,Gokhale NS,Abebe JS,Della Fera AN,Mason CE,Horner SM,Wilson AC,Depledge DP,Weitzman MD

更新日期：2020-11-26 00:00:00