Casimir forces on a silicon micromechanical chip.

abstract：:Cryptochrome (Cry) 1 and Cry2 are regarded as critical components for circadian rhythm generation in mammals. Nevertheless, cultured suprachiasmatic nucleus (SCN) of neonatal Cry double deficient (Cry1(-/-)/Cry2(-/-)) mice exhibit circadian rhythms that damp out in several cycles. Here, by combining bioluminescence im...

journal_title：Nature communications

authors： Ono D,Honma S,Honma K

更新日期：2013-01-01 00:00:00

abstract：:Post-translational protein modification by tyrosine sulfation has an important role in extracellular protein-protein interactions. The protein tyrosine sulfation reaction is catalysed by the Golgi enzyme called the tyrosylprotein sulfotransferase. To date, no crystal structure is available for tyrosylprotein sulfotran...

journal_title：Nature communications

authors： Teramoto T,Fujikawa Y,Kawaguchi Y,Kurogi K,Soejima M,Adachi R,Nakanishi Y,Mishiro-Sato E,Liu MC,Sakakibara Y,Suiko M,Kimura M,Kakuta Y

更新日期：2013-01-01 00:00:00

abstract：:Nacre-mimetics hold great promise as mechanical high-performance and functional materials. Here we demonstrate large progress of mechanical and functional properties of self-assembled polymer/nanoclay nacre-mimetics by using synthetic nanoclays with aspect ratios covering three orders in magnitude (25-3,500). We estab...

journal_title：Nature communications

authors： Das P,Malho JM,Rahimi K,Schacher FH,Wang B,Demco DE,Walther A

更新日期：2015-01-20 00:00:00

abstract：:Mapping neuroanatomy is a foundational goal towards understanding brain function. Electron microscopy (EM) has been the gold standard for connectivity analysis because nanoscale resolution is necessary to unambiguously resolve synapses. However, molecular information that specifies cell types is often lost in EM recon...

journal_title：Nature communications

authors： Shen FY,Harrington MM,Walker LA,Cheng HPJ,Boyden ES,Cai D

更新日期：2020-09-15 00:00:00

abstract：:Chloroplast function requires the coordinated action of nuclear- and chloroplast-derived proteins, including several hundred nuclear-encoded pentatricopeptide repeat (PPR) proteins that regulate plastid mRNA metabolism. Despite their large number and importance, regulatory mechanisms controlling PPR expression are poo...

journal_title：Nature communications

authors： Bailey M,Ivanauskaite A,Grimmer J,Akintewe O,Payne AC,Osborne R,Labandera AM,Etherington RD,Rantala M,Baginsky S,Mulo P,Gibbs DJ

更新日期：2021-01-11 00:00:00

abstract：:Planar neural networks and interfaces serve as versatile in vitro models of central nervous system physiology, but adaptations of related methods to three dimensions (3D) have met with limited success. Here, we demonstrate for the first time volumetric functional imaging in a bioengineered neural tissue growing in a t...

journal_title：Nature communications

authors： Dana H,Marom A,Paluch S,Dvorkin R,Brosh I,Shoham S

更新日期：2014-06-05 00:00:00

abstract：:Herpes simplex encephalitis (HSE) is the most common form of acute viral encephalitis in industrialized countries. Type I interferon (IFN) is important for control of herpes simplex virus (HSV-1) in the central nervous system (CNS). Here we show that microglia are the main source of HSV-induced type I IFN expression i...

journal_title：Nature communications

authors： Reinert LS,Lopušná K,Winther H,Sun C,Thomsen MK,Nandakumar R,Mogensen TH,Meyer M,Vægter C,Nyengaard JR,Fitzgerald KA,Paludan SR

更新日期：2016-11-10 00:00:00

abstract：:Express delivery services are booming in both developed and emerging economies due to their low cost, convenience, and the fast growth in online shopping. The increasing environmental impacts of express delivery services and mitigation potentials, however, remain largely unexplored. Here we addressed such a gap for Ch...

journal_title：Nature communications

authors： Kang P,Song G,Xu M,Miller TR,Wang H,Zhang H,Liu G,Zhou Y,Ren J,Zhong R,Duan H

更新日期：2021-01-19 00:00:00

abstract：:Long-chain alcohols synthesis (LAS, C5+OH) from syngas provides a promising route for the conversion of coal/biomass/natural gas into high-value chemicals. Cu-Fe binary catalysts, with the merits of cost effectiveness and high CO conversion, have attracted considerable attention. Here we report a nano-construct of a F...

journal_title：Nature communications

authors： Li Y,Gao W,Peng M,Zhang J,Sun J,Xu Y,Hong S,Liu X,Liu X,Wei M,Zhang B,Ma D

更新日期：2020-01-03 00:00:00

abstract：:Gold recovery using environmentally benign chemistry is imperative from an environmental perspective. Here we report the spontaneous assembly of a one-dimensional supramolecular complex with an extended {[K(OH₂)₆][AuBr₄](α-cyclodextrin)₂}n chain superstructure formed during the rapid co-precipitation of α-cyclodextrin...

journal_title：Nature communications

authors： Liu Z,Frasconi M,Lei J,Brown ZJ,Zhu Z,Cao D,Iehl J,Liu G,Fahrenbach AC,Botros YY,Farha OK,Hupp JT,Mirkin CA,Fraser Stoddart J

更新日期：2013-01-01 00:00:00

abstract：:Heparin-like oligosaccharides mediate numerous important biological interactions, of which many are implicated in various diseases. Synthetic improvements are central to the development of such oligosaccharides as therapeutics and, in addition, there are no methods to elucidate the pharmacokinetics of structurally def...

journal_title：Nature communications

authors： Hansen SU,Miller GJ,Cole C,Rushton G,Avizienyte E,Jayson GC,Gardiner JM

更新日期：2013-01-01 00:00:00

abstract：:Global emergence of Gram-negative bacteria carrying the plasmid-borne resistance genes, blaMBL and mcr, raises a significant challenge to the treatment of life-threatening infections by the antibiotics, carbapenem and colistin (COL). Here, we identify an antirheumatic drug, auranofin (AUR) as a dual inhibitor of metal...

journal_title：Nature communications

authors： Sun H,Zhang Q,Wang R,Wang H,Wong YT,Wang M,Hao Q,Yan A,Kao RY,Ho PL,Li H

更新日期：2020-10-16 00:00:00

abstract：:Diversity-oriented synthesis (DOS) can provide a collection of diverse and complex drug-like small molecules, which is critical in the development of new chemical probes for biological research of undruggable targets. However, the design and synthesis of small-molecule libraries with improved biological relevance as w...

journal_title：Nature communications

authors： Kim J,Jung J,Koo J,Cho W,Lee WS,Kim C,Park W,Park SB

更新日期：2016-10-24 00:00:00

abstract：:Fullerene peapods, which are carbon nanotubes encapsulating fullerene molecules, can offer enhanced functionality with respect to empty nanotubes. Their prospective applications include, for example, data storage devices, single-electron transistors and spin-qubit arrays for quantum computing. However, the present inc...

journal_title：Nature communications

authors： Utko P,Ferone R,Krive IV,Shekhter RI,Jonson M,Monthioux M,Noé L,Nygård J

更新日期：2010-07-13 00:00:00

abstract：:Acute graft-versus-host disease (GVHD) remains a major obstacle for the wider usage of allogeneic hematopoietic stem cell transplantation (allo-HSCT), which is an effective therapy for hematopoietic malignancy. Here we show that caspase-11, the cytosolic receptor for bacterial endotoxin (lipopolysaccharide: LPS), enha...

journal_title：Nature communications

authors： Lu Y,Meng R,Wang X,Xu Y,Tang Y,Wu J,Xue Q,Yu S,Duan M,Shan D,Wang Q,Wang H,Billiar TR,Xiao X,Chen F,Lu B

更新日期：2019-09-06 00:00:00

abstract：:Identification of the complete set of translated genes of viruses is important to understand viral replication and pathogenesis as well as for therapeutic approaches to control viral infection. Here, we use chemical proteomics, integrating bio-orthogonal non-canonical amino acid tagging and high-resolution mass spectr...

journal_title：Nature communications

authors： Kato A,Adachi S,Kawano S,Takeshima K,Watanabe M,Kitazume S,Sato R,Kusano H,Koyanagi N,Maruzuru Y,Arii J,Hatta T,Natsume T,Kawaguchi Y

更新日期：2020-09-29 00:00:00

abstract：:Crosstalk between inflammatory signalling pathways and receptor tyrosine kinases has been revealed as an indicator of cancer malignant progression. In the present study, we focus on EphA2 receptor tyrosine kinase, which is overexpressed in many human cancers. It has been reported that ligand-independent phosphorylatio...

journal_title：Nature communications

authors： Zhou Y,Yamada N,Tanaka T,Hori T,Yokoyama S,Hayakawa Y,Yano S,Fukuoka J,Koizumi K,Saiki I,Sakurai H

更新日期：2015-07-09 00:00:00

abstract：:Sequencing of a single-cell genome requires DNA amplification, a process prone to introducing bias and errors into the amplified genome. Here we introduce a novel multiple displacement amplification (MDA) method based on the unique DNA primase features of Thermus thermophilus (Tth) PrimPol. TthPrimPol displays a poten...

journal_title：Nature communications

authors： Picher ÁJ,Budeus B,Wafzig O,Krüger C,García-Gómez S,Martínez-Jiménez MI,Díaz-Talavera A,Weber D,Blanco L,Schneider A

更新日期：2016-11-29 00:00:00

abstract：:The efficient selection and isolation of individual cells of interest from a mixed population is desired in many biomedical and clinical applications. Here we show the concept of using photoswitchable semiconducting polymer dots (Pdots) as an optical 'painting' tool, which enables the selection of certain adherent cel...

journal_title：Nature communications

authors： Kuo CT,Thompson AM,Gallina ME,Ye F,Johnson ES,Sun W,Zhao M,Yu J,Wu IC,Fujimoto B,DuFort CC,Carlson MA,Hingorani SR,Paguirigan AL,Radich JP,Chiu DT

更新日期：2016-04-27 00:00:00

abstract：:Dislocation defects together with their associated strain fields and segregated impurities are of considerable significance in many areas of materials science. However, their atomic-scale structures have remained extremely challenging to resolve, limiting our understanding of these ubiquitous defects. Here, by develop...

journal_title：Nature communications

authors： Wang Z,Saito M,McKenna KP,Ikuhara Y

更新日期：2014-01-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Hart Y,Goldberg H,Striem-Amit E,Mayo AE,Noy L,Alon U

更新日期：2020-02-24 00:00:00

abstract：:Understanding the formation chemistry of metal halide perovskites is key to optimizing processing conditions and realizing enhanced optoelectronic properties. Here, we reveal the structure of the crystalline precursor in the formation of methylammonium lead iodide (MAPbI3) from the single-step deposition of lead chlor...

journal_title：Nature communications

authors： Stone KH,Gold-Parker A,Pool VL,Unger EL,Bowring AR,McGehee MD,Toney MF,Tassone CJ

更新日期：2018-08-27 00:00:00

abstract：:The Middle Eocene Climatic Optimum (MECO) represents a ~500-kyr period of global warming ~40 million years ago and is associated with a rise in atmospheric CO2 concentrations, but the cause of this CO2 rise remains enigmatic. Here we show, based on osmium isotope ratios (187Os/188Os) of marine sediments and published ...

journal_title：Nature communications

authors： van der Ploeg R,Selby D,Cramwinckel MJ,Li Y,Bohaty SM,Middelburg JJ,Sluijs A

更新日期：2018-07-23 00:00:00

abstract：:The Non-Proliferation Treaty and other non-proliferation agreements are in place worldwide to ensure that nuclear material and facilities are used only for peaceful purposes. Antineutrino detectors, sensitive to reactor power and fuel changes, can complement the tools already at the disposal of international agencies ...

journal_title：Nature communications

authors： Stewart C,Abou-Jaoude A,Erickson A

更新日期：2019-08-06 00:00:00

abstract：:Foldamers provide an attractive medium to test the mechanisms by which biological macromolecules fold into complex three-dimensional structures, and ultimately to design novel protein-like architectures with properties unprecedented in nature. Here, we describe a large cage-like structure formed from an amphiphilic ar...

journal_title：Nature communications

authors： Pavone V,Zhang SQ,Merlino A,Lombardi A,Wu Y,DeGrado WF

更新日期：2014-04-07 00:00:00

abstract：:During bacterial cell division, the tubulin-homolog FtsZ forms a ring-like structure at the center of the cell. This Z-ring not only organizes the division machinery, but treadmilling of FtsZ filaments was also found to play a key role in distributing proteins at the division site. What regulates the architecture, dyn...

journal_title：Nature communications

authors： Caldas P,López-Pelegrín M,Pearce DJG,Budanur NB,Brugués J,Loose M

更新日期：2019-12-17 00:00:00

abstract：:Optical spectroscopy is a fundamental tool in numerous areas of science and technology. Much effort has focused on miniaturizing spectrometers, but thus far at the cost of spectral resolution and broad operating range. Here we describe a compact spectrometer that achieves both high spectral resolution and broad bandwi...

journal_title：Nature communications

authors： Wan NH,Meng F,Schröder T,Shiue RJ,Chen EH,Englund D

更新日期：2015-07-23 00:00:00

abstract：:Hybrid halide perovskite solar cells were first demonstrated in 2009 with cell efficiency quickly soaring from below 10% to more than 23% in a few years. Halide perovskites have the desirable processing simplicity but are very fragile when exposed to water and heat. This fragility represents a great challenge for the ...

journal_title：Nature communications

authors： Gao P,Bin Mohd Yusoff AR,Nazeeruddin MK

更新日期：2018-11-28 00:00:00

abstract：:Lithium metal is an ideal battery anode. However, dendrite growth and limited Coulombic efficiency during cycling have prevented its practical application in rechargeable batteries. Herein, we report that the use of highly concentrated electrolytes composed of ether solvents and the lithium bis(fluorosulfonyl)imide sa...

journal_title：Nature communications

authors： Qian J,Henderson WA,Xu W,Bhattacharya P,Engelhard M,Borodin O,Zhang JG

更新日期：2015-02-20 00:00:00

abstract：:The extent to which the impact of regulatory genetic variants may depend on other factors, such as the expression levels of upstream transcription factors, remains poorly understood. Here we report a framework in which regulatory variants are first aggregated into sets, and using these as estimates of the total cis-ge...

journal_title：Nature communications

authors： Wragg D,Liu Q,Lin Z,Riggio V,Pugh CA,Beveridge AJ,Brown H,Hume DA,Harris SE,Deary IJ,Tenesa A,Prendergast JGD

更新日期：2020-01-17 00:00:00