Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Abusara Z,Andrews SHJ,Von Kossel M,Herzog Wdoi
10.1038/s41598-019-40293-3subject
Has Abstractpub_date
2019-04-09 00:00:00pages
5975issue
1issn
2045-2322pii
10.1038/s41598-019-40293-3journal_volume
9pub_type
已发布勘误abstract::A delicate balance between proliferating and differentiating signals is necessary to ensure proper growth and neuronal specification. By studying the developing zebrafish brain, we observed a specific and dynamic expression of a microtubule destabilizer gene, stathmin-like 4 (stmn4), in the dorsal midbrain region. The...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36188
更新日期:2016-11-07 00:00:00
abstract::Knowledge of the genomic variation among different strains of a pathogenic microbial species can help in selecting optimal candidates for diagnostic assays and vaccine development. Pooled sequencing (Pool-seq) is a cost effective approach for population level genetic studies that require large numbers of samples such ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45771
更新日期:2017-03-31 00:00:00
abstract::Increasing life expectancy and a growing share of older people around the world spotlight the issue of health during additional years of life. Research on trends of proportions of older people with activity limitations for low and middle income countries is sparse. We use data from the World Health Survey and the UN W...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67166-4
更新日期:2020-06-26 00:00:00
abstract::The ultrathin SmCo5 nanoflakes with average thickness smaller than 50 nm are prepared by a novel method of solid particle (NaCl) and surfactant co-assisted ball milling. The as-prepared nanoflakes exhibit a narrower thickness distribution of 10-50 nm and high coercivity of 23 kOe. The possible formation mechanism of n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25805
更新日期:2016-05-13 00:00:00
abstract::A growing interest in healthy eating has lead to an increase in the consumption of vegetables, associated with a rising number of bacterial outbreaks related to fresh produce. This is the case of the outbreak in Germany, caused by a O104:H4 enteroaggregative E. coli strain lysogenic for a Stx phage. Temperate Stx phag...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08169-6
更新日期:2017-08-10 00:00:00
abstract::Jute fibre is the second most important fibre next to cotton. It is obtained from the bark of plant through microbial retting process. Here we report optimized microbial retting protocol that can lower retting period and produce high fibre quality. A total of 451 bacterial colonies have been isolated from five jute re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61898-z
更新日期:2020-03-20 00:00:00
abstract::The spread of multidrug-resistant Staphylococcus aureus strains, including methicillin-resistant S. aureus (MRSA), has shortened the useful life of anti-staphylococcal drugs enormously. Two approaches can be followed to address this problem: screening various sources for new leads for antibiotics or finding ways to di...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03716-7
更新日期:2017-06-19 00:00:00
abstract::MicroRNAs (miRNAs) have been reported to be involved in DNA damage response induced by ionizing radiation (IR). c-Myc is reduced when cells treated with IR or other DNA damaging agents. It is unknown whether miRNAs participate in c-Myc downregulation in response to IR. In the present study, we found that miR-449a enha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27346
更新日期:2016-06-02 00:00:00
abstract::Extranodal NK/T-cell lymphoma, nasal type (NKTL) is an aggressive type of non-Hodgkin lymphoma closely associated with Epstein-Barr virus and characterized by varying degrees of systemic inflammation. We aim to examine the prognostic significance of peripheral blood neutrophil-lymphocyte ratio (NLR) in patients with N...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究
doi:10.1038/s41598-019-51522-0
更新日期:2019-10-18 00:00:00
abstract::Landau-Zener (LZ) transition has received renewed interest as an alternative approach to control single-qubit states. An LZ transition occurs when a system passes through an avoided crossing that arises from quantum mechanical coupling of two levels, taking the system to a coherent superposition of the two states. The...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23468-2
更新日期:2018-04-03 00:00:00
abstract::Microbial life below the seafloor has changed over geological time, but these changes are often not obvious, as they are not recorded in the sediment. Sulphur (S) isotope values in pyrite extracted from a Plio- to Holocene sequence of the Peru Margin (Ocean Drilling Program, ODP, Site 1229) show a down-core pattern th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36943-7
更新日期:2019-01-24 00:00:00
abstract::Although previous findings identified an association between C-reactive protein (CRP) levels, and impaired cognitive functions in patients with schizophrenia (SZ), little is currently known about the relationship between inflammation, cognition, and sex in SZ. The current study aimed to explore the association between...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73043-x
更新日期:2020-09-29 00:00:00
abstract::The Thoroughbred horse has played an important role in both sporting and economic aspects of society since the establishment of the breed in the 1700s. The extensive pedigree and phenotypic information available for the Thoroughbred horse population provides a unique opportunity to examine the effects of 300 years of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24663-x
更新日期:2018-04-18 00:00:00
abstract::The chemiresistive thin film gas sensors with fast response, high sensitivity, low power consumption and mass-produced potency, have been expected for practical application. It requires both sensitive materials, especially exquisite nanomaterials, and efficient substrate chip for heating and electrical addressing. How...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01669
更新日期:2013-01-01 00:00:00
abstract::Although it is well known that mean annual rainfall (MAR) and rainfall seasonality have a key role in influencing the distribution of tree and grass cover in African tropical grassy biomes (TGBs), the impact of intra-seasonal rainfall variability on these distributions is less agreed upon. Since the prevalent mechanis...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38933-9
更新日期:2019-02-20 00:00:00
abstract::Tumor aggressiveness is usually associated with metastasis. MDA-MB 231, a triple-negative breast cancer (TNBC), is an aggressive type of breast cancer and associated with early metastasis. The Rho/ROCK pathway is a key regulator of cell motility involving cytoskeleton regulation through stabilization of actin filament...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14216-z
更新日期:2017-10-20 00:00:00
abstract::Papain-like cysteine proteases (PLCPs) are a class of proteolytic enzymes involved in many plant processes. Compared with the extensive research in Arabidopsis thaliana, little is known in castor bean (Ricinus communis) and physic nut (Jatropha curcas), two Euphorbiaceous plants without any recent whole-genome duplica...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18760-6
更新日期:2018-01-10 00:00:00
abstract::Automated patch clamp (APC) instruments enable efficient evaluation of electrophysiologic effects of drugs on human cardiac currents in heterologous expression systems. Differences in experimental protocols, instruments, and dissimilar site procedures affect the variability of IC50 values characterizing drug block pot...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62344-w
更新日期:2020-03-27 00:00:00
abstract::Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high sodium ion conductivity into the zeolitic imidazolate framework ZIF-8 by impregnation with the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60198-w
更新日期:2020-02-26 00:00:00
abstract::Impaired immune function contributes to the development of chronic obstructive pulmonary disease (COPD). Disease progression is further exacerbated by pathogen infections due to impaired immune responses. Elimination of infected cells is achieved by cytotoxic CD8(+) T cells that are activated by MHC I-mediated presen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10230
更新日期:2015-05-19 00:00:00
abstract::Developing therapeutics that target multiple receptor signaling pathways in tumors is critical as therapies targeting single specific biomarker/pathway have shown limited efficacy in patients with cancer. In this study, we extensively characterized a bi-functional molecule comprising of epidermal growth factor recepto...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02483-9
更新日期:2017-06-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-60910-w
更新日期:2020-02-28 00:00:00
abstract::Dental caries is an important public health problem worldwide. This study aims to prove how preventive therapies reduce the onset of caries in adult patients, and to identify patients with high or low risk of caries by using Classification and Regression Trees based survival analysis (survival CART). A clinical data s...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究
doi:10.1038/srep29190
更新日期:2016-07-06 00:00:00
abstract::Accidental introduction through ballast water and biofouling are currently the main factors responsible for spreading non-indigenous species in the marine realm. In the Southwestern Atlantic, two scleractinian corals, Tubastraea coccinea and T. tagusensis, have been introduced by opportunistic colonization in 1980 and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50442-3
更新日期:2019-09-27 00:00:00
abstract::Thrombin-induced and proteinase-activated receptor 1 (PAR1)-mediated signaling increases ROS production, activates ERK, and promotes inflammation and fibroblast proliferation in bleomycin-induced lung injury. Stanniocalcin-1 (STC1) activates anti-oxidant pathways, inhibits inflammation and provides cytoprotection; hen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18117
更新日期:2015-12-07 00:00:00
abstract::Although the association between visual acuity (VA) and vision-related quality of life (VRQoL) has been well reported in patients with type 2 diabetes mellitus (T2DM), little is known about how unilateral and bilateral VA affects daily performance in such patients. For this cross-sectional study, patients were recruit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79483-9
更新日期:2021-01-11 00:00:00
abstract::The TREX complex mediates the passage of bulk cellular mRNA export to the nuclear export factor TAP/NXF1 via the export adaptors ALYREF or UIF, which appear to act in a redundant manner. TREX complex recruitment to nascent RNA is coupled with 5' capping, splicing and polyadenylation. Therefore to facilitate expression...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33379-x
更新日期:2018-10-09 00:00:00
abstract::Parasitic lice (order Phthiraptera) infest birds and mammals. The typical animal mitochondrial (mt) genome organization, which consists of a single chromosome with 37 genes, was found in chewing lice in the suborders Amblycera and Ischnocera. The sucking lice (suborder Anoplura) known, however, have fragmented mt geno...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17389
更新日期:2015-11-30 00:00:00
abstract::Rapid urbanization is a global phenomenon that has altered many ecosystems, generating ecological risks such as causing a decline in many ecosystem services. In this study, ecosystem service oriented risk assessment combined with PSR were quantifying how urbanization influences the ecosystem services about Beijing-Tia...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52719-z
更新日期:2019-11-14 00:00:00
abstract::Genome editing tools have revolutionized the generation of genetically modified animals including livestock. In particular, the domestic pig is a proven model of human physiology and an agriculturally important species. In this study, we utilized the CRISPR/Cas9 system to edit the NANOS2 gene in pig embryos to generat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40176
更新日期:2017-01-10 00:00:00