Abstract:
:Electron transport in two-dimensional conducting materials such as graphene, with dominant electron-electron interaction, exhibits unusual vortex flow that leads to a nonlocal current-field relation (negative resistance), distinct from the classical Ohm's law. The transport behavior of these materials is best described by low Reynolds number hydrodynamics, where the constitutive pressure-speed relation is Stoke's law. Here we report evidence of such vortices observed in a viscous flow of Newtonian fluid in a microfluidic device consisting of a rectangular cavity-analogous to the electronic system. We extend our experimental observations to elliptic cavities of different eccentricities, and validate them by numerically solving bi-harmonic equation obtained for the viscous flow with no-slip boundary conditions. We verify the existence of a predicted threshold at which vortices appear. Strikingly, we find that a two-dimensional theoretical model captures the essential features of three-dimensional Stokes flow in experiments.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Mayzel J,Steinberg V,Varshney Adoi
10.1038/s41467-019-08916-5subject
Has Abstractpub_date
2019-02-26 00:00:00pages
937issue
1issn
2041-1723pii
10.1038/s41467-019-08916-5journal_volume
10pub_type
杂志文章abstract::Increased lipogenesis has been linked to an increased cancer risk and poor prognosis; however, the underlying mechanisms remain obscure. Here we show that phosphatidic acid phosphatase (PAP) lipin-1, which generates diglyceride precursors necessary for the synthesis of glycerolipids, interacts with and is a direct sub...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19694-w
更新日期:2020-11-17 00:00:00
abstract::Macrophage-mediated inflammation is thought to have a causal role in osteoarthritis-related pain and severity, and has been suggested to be triggered by endotoxins produced by the gastrointestinal microbiome. Here we investigate the relationship between joint pain and the gastrointestinal microbiome composition, and o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12873-4
更新日期:2019-10-25 00:00:00
abstract::As European heatwaves become more severe, summers in the United Kingdom (UK) are also getting warmer. The UK record temperature of 38.7 °C set in Cambridge in July 2019 prompts the question of whether exceeding 40 °C is now within reach. Here, we show how human influence is increasing the likelihood of exceeding 30, 3...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16834-0
更新日期:2020-06-30 00:00:00
abstract::The original version of this Article was missing the ORCID ID of Professor Nicola Pugno.Also in the original version of this Article, the third to last sentence of the fourth paragraph of the Results incorrectly read 'However, the stepwise addition of CNTs increases the self-entanglement and thereby the compressive st...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-017-02372-9
更新日期:2018-01-09 00:00:00
abstract::The divalent carbene carbon centre in cyclic (alkyl)(amino)carbenes (CAACs) is known to exhibit transition-metal-like insertion into E-H σ-bonds (E = H, N, Si, B, P, C, O) with formation of new, strong C-E and C-H bonds. Although subsequent transformations of the products represent an attractive strategy for metal-fre...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08967-8
更新日期:2019-03-26 00:00:00
abstract::The original version of this Article contained an error in the spelling of the author Woochul Song, which was incorrectly given as Woochul C. Song. This has been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-05447-3
更新日期:2018-08-14 00:00:00
abstract::In the original version of this Article, the affiliation details for Antoine Aze, Michalis Fragkos, Stéphane Bocquet, Julien Cau and Marcel Méchali incorrectly omitted 'CNRS and the University of Montpellier'. This has now been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-02968-9
更新日期:2018-02-05 00:00:00
abstract::Nature has developed striking light-powered proteins such as bacteriorhodopsin, which can convert light energy into conformational changes for biological functions. Such natural machines are a great source of inspiration for creation of their synthetic analogues. However, synthetic molecular machines typically operate...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10591
更新日期:2016-02-02 00:00:00
abstract::Membranes with nano-apertures are versatile templates that possess a wide range of electronic, optical and biomedical applications. However, such membranes have been limited to silicon-based inorganic materials to utilize standard semiconductor processes. Here we report a new type of flexible and free-standing polymer...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4137
更新日期:2014-01-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-020-15800-0
更新日期:2020-04-20 00:00:00
abstract::Global emergence of Gram-negative bacteria carrying the plasmid-borne resistance genes, blaMBL and mcr, raises a significant challenge to the treatment of life-threatening infections by the antibiotics, carbapenem and colistin (COL). Here, we identify an antirheumatic drug, auranofin (AUR) as a dual inhibitor of metal...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18939-y
更新日期:2020-10-16 00:00:00
abstract::Thoracian barnacles rely heavily upon their ability to adhere to surfaces and are environmentally and economically important as biofouling pests. Their adhesives have unique attributes that define them as targets for bio-inspired adhesive development. With the aid of multi-photon and broadband coherent anti-Stokes Ram...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5414
更新日期:2014-07-11 00:00:00
abstract::Nonsense-mediated decay (NMD) eliminates transcripts with premature termination codons. Although NMD-induced loss-of-function has been shown to contribute to the genesis of particular cancers, its global functional consequence in tumours has not been characterized. Here we develop an algorithm to predict NMD and apply...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15943
更新日期:2017-06-26 00:00:00
abstract::To reconstruct the evolutionary origin of multicellular animals from their unicellular ancestors, the genome sequences of diverse unicellular relatives are essential. However, only the genome of the choanoflagellate Monosiga brevicollis has been reported to date. Here we completely sequence the genome of the filastere...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3325
更新日期:2013-01-01 00:00:00
abstract::Complex tissue-specific and cell-specific signaling by the estrogen receptor (ER) frequently leads to the development of resistance to endocrine therapy for breast cancer. Pure ER antagonists, which completely lack tissue-specific agonist activity, hold promise for preventing and treating endocrine resistance, however...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04413-3
更新日期:2018-06-18 00:00:00
abstract::Although B cell response is frequently found in cancer, there is little evidence that it alters tumor development or progression. The process through which tumor-associated antigens trigger humoral response is not well delineated. We investigate the repertoire of antigens associated with humoral immune response in pan...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08109-6
更新日期:2019-01-16 00:00:00
abstract::The recent outbreak of Zika virus (ZIKV) has imposed a serious threat to public health. Here we report the crystal structure of the ZIKV NS5 protein in complex with S-adenosyl-L-homocysteine, in which the tandem methyltransferase (MTase) and RNA-dependent RNA polymerase (RdRp) domains stack into one of the two alterna...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14763
更新日期:2017-03-27 00:00:00
abstract::Small interfering RNAs (siRNAs) conjugated to a trivalent N-acetylgalactosamine (GalNAc) ligand are being evaluated in investigational clinical studies for a variety of indications. The typical development candidate selection process includes evaluation of the most active compounds for toxicity in rats at pharmacologi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-02989-4
更新日期:2018-02-19 00:00:00
abstract::Human land use may detrimentally affect biodiversity, yet long-term stability of species communities is vital for maintaining ecosystem functioning. Community stability can be achieved by higher species diversity (portfolio effect), higher asynchrony across species (insurance hypothesis) and higher abundance of popula...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10697
更新日期:2016-02-12 00:00:00
abstract::A non-classical light source emitting pairs of identical photons represents a versatile resource of interdisciplinary importance with applications in quantum optics and quantum biology. To date, photon twins have mostly been generated using parametric downconversion sources, relying on Poissonian number distributions,...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14870
更新日期:2017-04-03 00:00:00
abstract::The development of theories and methods devoted to the accurate calculation of the electronic quasi-particle states and levels of molecules, clusters and solids is of prime importance to interpret the experimental data. These quantum systems are often modelled by using the Born-Oppenheimer approximation where the coup...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11327
更新日期:2016-04-22 00:00:00
abstract::Subduction zone magmas are more oxidised on eruption than those at mid-ocean ridges. This is attributed either to oxidising components, derived from subducted lithosphere (slab) and added to the mantle wedge, or to oxidation processes occurring during magma ascent via differentiation. Here we provide direct evidence f...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05804-2
更新日期:2018-08-29 00:00:00
abstract::Understanding the molecular parameters that regulate cross-species transmission and host adaptation of potential pathogens is crucial to control emerging infectious disease. Although microbial pathotype diversity is conventionally associated with gene gain or loss, the role of pathoadaptive nonsynonymous single-nucleo...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9754
更新日期:2015-10-30 00:00:00
abstract::As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different types of cancer, chronic lymphocytic leukaemia and medulloblastoma, we conduct a benchmarking e...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10001
更新日期:2015-12-09 00:00:00
abstract::Synthetic polymers are indispensable in many different applications, but there is a growing need for green processes and natural surfactants for emulsion polymerization. The use of solid particles to stabilize Pickering emulsions is a particularly attractive avenue, but oxygen sensitivity has remained a formidable cha...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19407-3
更新日期:2020-11-05 00:00:00
abstract::Ultra-small, magic-sized metal nanoclusters represent an important new class of materials with properties between molecules and particles. However, their small size challenges the conventional methods for structure characterization. Here we present the structure of ultra-stable Au144(SR)60 magic-sized nanoclusters obt...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11859
更新日期:2016-06-14 00:00:00
abstract::Tenuazonic acid (TeA) is a well-known mycotoxin produced by various plant pathogenic fungi. However, its biosynthetic gene has been unknown to date. Here we identify the TeA biosynthetic gene from Magnaporthe oryzae by finding two TeA-inducing conditions of a low-producing strain. We demonstrate that TeA is synthesize...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9758
更新日期:2015-10-27 00:00:00
abstract::Fourier ring correlation (FRC) has recently gained popularity among fluorescence microscopists as a straightforward and objective method to measure the effective image resolution. While the knowledge of the numeric resolution value is helpful in e.g., interpreting imaging results, much more practical use can be made o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11024-z
更新日期:2019-07-15 00:00:00
abstract::Drop motility at liquid surfaces is attracting growing interest because of its potential applications in microfluidics and artificial cell design. Here we report the unique highly ordered pattern that sets in when a millimeter-size drop of dichloromethane spreads on an aqueous substrate under the influence of surface ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03201-3
更新日期:2018-02-26 00:00:00
abstract::The gut-derived orexigenic peptide hormone ghrelin enhances neuronal firing in the substantia nigra pars compacta, where dopaminergic neurons modulate the function of the nigrostriatal system for motor coordination. Here we describe a novel mechanism by which ghrelin enhances firing of nigral dopaminergic neurons by i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2439
更新日期:2013-01-01 00:00:00