Combination of Platelet expression of PKCepsilon and cardiac troponin-I for early diagnosis of chest pain patients in the emergency department.

abstract：:At the regional scale, although environmental factors are known to shape the distributions of belowground communities in terrestrial ecosystems, these environmental factors account for relatively low percentages of the variation in belowground communities. More of this variation might be explained by considering ecosy...

journal_title：Scientific reports

authors： Wang B,Wu Y,Chen D

更新日期：2017-08-04 00:00:00

abstract：:Present study aimed to estimate the incidence of recurrent SARS-CoV-2 RNA positivity after recovery from COVID-19 and to determine the factors associated with recurrent positivity. We searched the PubMed, MedRxiv, BioRxiv, the Cochrane Library, ClinicalTrials.gov, and the World Health Organization International Clinic...

journal_title：Scientific reports

authors： Azam M,Sulistiana R,Ratnawati M,Fibriana AI,Bahrudin U,Widyaningrum D,Aljunid SM

更新日期：2020-11-26 00:00:00

abstract：:We collected Solidago altissima clones to explore their leaf damage resistance, and as a result identified five accessions that exhibited variable defense abilities against the generalist herbivore Spodoptera litura. In order to characterize molecules involved in such natural variation, we focused on ethylene response...

journal_title：Scientific reports

authors： Takafuji K,Rim H,Kawauchi K,Mujiono K,Shimokawa S,Ando Y,Shiojiri K,Galis I,Arimura GI

更新日期：2020-03-24 00:00:00

abstract：:Maternal obesity in pregnancy increases the risk of adverse long-term health outcomes in both mother and offspring. A population-based cohort of prospectively collected routine antenatal healthcare data collected between January 2003 and September 2017 at University Hospital Southampton, UK was utilised to investigate...

journal_title：Scientific reports

authors： Ziauddeen N,Roderick PJ,Macklon NS,Alwan NA

更新日期：2019-06-24 00:00:00

abstract：:The present study investigates the impact of charge variants on bevacizumab's structure, stability, and biological activity. Five basic and one acidic charge variants were separated using semi-preparative cation exchange chromatography using linear pH gradient elution with purity > 85%. Based on the commercial biosimi...

journal_title：Scientific reports

authors： Singh SK,Kumar D,Malani H,Rathore AS

更新日期：2021-01-29 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep44640. ...

journal_title：Scientific reports

authors： Dong S,Wen P,Zhang Q,Li X,Tan K,Nieh J

更新日期：2017-06-30 00:00:00

abstract：:Acute kidney injury (AKI) in patients with septic shock is associated with high mortality, but the appropriate timing for initiating continuous renal replacement therapy (CRRT) is controversial. We retrospectively enrolled 158 septic shock patients with AKI in the medical intensive care unit (ICU) from July 2016 to Ap...

journal_title：Scientific reports

authors： Yoon BR,Leem AY,Park MS,Kim YS,Chung KS

更新日期：2019-08-19 00:00:00

abstract：:The objective of this study was to unveil the potential mechanism of focused ultrasound (FUS)-enhanced intranasal (IN) brain drug delivery and assess its feasibility in the delivery of therapeutic molecules. Delivery outcomes of fluorescently-labeled dextrans to mouse brains by IN administration either before or after...

journal_title：Scientific reports

authors： Chen H,Yang GZ,Getachew H,Acosta C,Sierra Sánchez C,Konofagou EE

更新日期：2016-06-27 00:00:00

abstract：:It is known that ribosomal RNA (rRNA) synthesis is regulated by cellular energy and proliferation status. In this study, we investigated rRNA gene transcription in response to cytoskeletal stress. Our data revealed that the cell shape constrained by isotropic but not elongated micropatterns in HeLa cells led to a sign...

journal_title：Scientific reports

authors： Wu TH,Kuo YY,Lee HH,Kuo JC,Ou MH,Chang ZF

更新日期：2016-06-28 00:00:00

abstract：:Synthetic analogues of mycobacterial trehalose-dimycolate such as trehalose acyl esters have been proposed as novel adjuvants for vaccination. They induce an immune response by binding to the macrophage C-type lectin receptor Mincle. The binding site of trehalose is known, but there is yet only very limited structural...

journal_title：Scientific reports

authors： Söldner CA,Horn AHC,Sticht H

更新日期：2018-03-29 00:00:00

abstract：:E. coli expressed recombinant basic fibroblast growth factor (bFGF) with histidine-tag (bFGF-His) was immobilized onto the surface of a glass plate modified with a Ni(II)-chelated alkanethiol monolayer. The immobilization is expected to take place through the coordination between Ni(II) and His-tag. The bFGF-immobiliz...

journal_title：Scientific reports

authors： Shakya A,Imado E,Nguyen PK,Matsuyama T,Horimoto K,Hirata I,Kato K

更新日期：2020-05-29 00:00:00

abstract：:Saccharomyces cerevisiae is a robust host for heterologous protein expression. The efficient expression of cellulases in S. cerevisiae is important for the consolidated bioprocess that directly converts lignocellulose into valuable products. However, heterologous proteins are often N-hyperglycosylated in S. cerevisiae...

journal_title：Scientific reports

authors： Tang H,Wang S,Wang J,Song M,Xu M,Zhang M,Shen Y,Hou J,Bao X

更新日期：2016-05-09 00:00:00

abstract：:One of the greatest enigmas of modern biology is how the geometry of muscular and skeletal structures are created and how their development is controlled during growth and regeneration. Scaling and shaping of vertebrate muscles and skeletal elements has always been enigmatic and required an advanced technical level in...

journal_title：Scientific reports

authors： Tesařová M,Mancini L,Simon A,Adameyko I,Kaucká M,Elewa A,Lanzafame G,Zhang Y,Kalasová D,Szarowská B,Zikmund T,Novotná M,Kaiser J

更新日期：2018-09-20 00:00:00

abstract：:A potted experiment with Populus × euramericana 'Neva' was carried out to assess whether there are positive effects of magnetic treatment of saline water (MTSW) on nitrogen metabolism under controlled conditions in a greenhouse. Growth properties, nitrogen contents, enzyme activities and metabolite concentrations were...

journal_title：Scientific reports

authors： Liu X,Zhu H,Wang L,Bi S,Zhang Z,Meng S,Zhang Y,Wang H,Song C,Ma F

更新日期：2019-07-11 00:00:00

abstract：:To evaluate crop rotation effects on maize seedling performance and its associated microbiome, maize plants were grown in the greenhouse in soils preceded by either maize, pea, soybean or sunflower. Soils originated from a replicated field experiment evaluating different four-year rotation combinations. In the greenho...

journal_title：Scientific reports

authors： Benitez MS,Osborne SL,Lehman RM

更新日期：2017-11-16 00:00:00

abstract：:Primordial germ cells (PGCs), the embryonic precursors of the sperm and egg, are used for the introduction of genetic modifications into avian genome. Introduction of small defined sequences using genome editing has not been demonstrated in bird species. Here, we compared oligonucleotide-mediated HDR using wild type S...

journal_title：Scientific reports

authors： Idoko-Akoh A,Taylor L,Sang HM,McGrew MJ

更新日期：2018-10-11 00:00:00

abstract：:Osteosarcoma (OS) is the most common bone tumor characterized with a high risk of amputation and malignant morbidity among teenagers and adolescents. However, relevant pathogenic/biological mechanisms underlying OS-genesis remains to be ambiguous. The aim of this study was to elucidate functional relationship about mi...

journal_title：Scientific reports

authors： Wang H,Tang M,Ou L,Hou M,Feng T,Huang YE,Jin Y,Zhang H,Zuo G

更新日期：2017-07-14 00:00:00

abstract：:Magnetic-charge ordering and corresponding magnetic/monopole phase transitions in spin ices are the emergent topics of condensed matter physics. In this work, we investigate a series of magnetic-charge (monopole) phase transitions in artificial square spin ice model using the conserved monopole density algorithm. It i...

journal_title：Scientific reports

authors： Xie YL,Du ZZ,Yan ZB,Liu JM

更新日期：2015-10-29 00:00:00

abstract：:We compared the effects of 12-week programs of resistance training (RT), high-intensity interval aerobic training (HIAT), and moderate-intensity continuous aerobic training (MICT). The primary goal was to evaluate the therapeutic effects of the exercise modalities for the management of nonalcoholic fatty liver disease...

journal_title：Scientific reports

authors： Oh S,So R,Shida T,Matsuo T,Kim B,Akiyama K,Isobe T,Okamoto Y,Tanaka K,Shoda J

更新日期：2017-02-22 00:00:00

abstract：:Photodynamic therapy is attracting increasing attention, but how to increase its tumor-specificity remains a daunting challenge. Herein we report a theranostic probe (azo-PDT) that integrates pyropheophorbide α as a photosensitizer and a NIR fluorophore for tumor imaging. The two functionalities are linked with a hypo...

journal_title：Scientific reports

authors： Wang C,Wang S,Wang Y,Wu H,Bao K,Sheng R,Li X

更新日期：2020-07-22 00:00:00

abstract：:The aim of this study was to estimate the influence of regenerated tobacco on the extraction of Cd from two acidic soils as well as to address the problem of how to deal with contaminated leaves following phytoextraction. Results showed that a coppicing tobacco led to a decline in Cd concentration in regenerated leave...

journal_title：Scientific reports

authors： Yang Y,Ge Y,Zeng H,Zhou X,Peng L,Zeng Q

更新日期：2017-08-03 00:00:00

abstract：:Harvesting light for optical torque is of significant importance, owing to its ability to rotate nano- or micro-objects. Nevertheless, applying a strong optical torque remains a challenging task: angular momentum must conserve but light is limited. A simple argument shows the tendency for two objects with strong mutua...

journal_title：Scientific reports

authors： Chen J,Wang N,Cui L,Li X,Lin Z,Ng J

更新日期：2016-06-13 00:00:00

abstract：:Alternative splicing contributes to phenotypic diversity at multiple biological scales, and its dysregulation is implicated in both ageing and age-associated diseases in human. Cross-tissue variability in splicing further complicates its links to age-associated phenotypes and elucidating these links requires a compreh...

journal_title：Scientific reports

authors： Wang K,Wu D,Zhang H,Das A,Basu M,Malin J,Cao K,Hannenhalli S

更新日期：2018-07-19 00:00:00

abstract：:Methadone maintenance treatment (MMT) can induce impairments in brain function and structure, despite its clinical effectiveness. However, the effect of chronic MMT on brain white matter (WM) is not fully known. Thirty-three MMT patients underwent diffusion tensor imaging (DTI) twice - at the start of the study (Scan1...

journal_title：Scientific reports

authors： Li W,Li Q,Wang Y,Zhu J,Ye J,Yan X,Li Y,Chen J,Liu J,Li Z,Wang W,Liu Y

更新日期：2016-01-22 00:00:00

abstract：:Cardiac fibroblasts are present throughout the myocardium and are enriched in the microenvironment surrounding the ventricular conduction system (VCS). Several forms of arrhythmias are linked to VCS abnormalities, but it is still unclear whether VCS malformations are cardiomyocyte autonomous or could be linked to cros...

journal_title：Scientific reports

authors： Ribeiro da Silva A,Neri EA,Turaça LT,Dariolli R,Fonseca-Alaniz MH,Santos-Miranda A,Roman-Campos D,Venturini G,Krieger JE

更新日期：2020-09-30 00:00:00

abstract：:Sphingolipids are essential constituents of the plasma membrane (PM) and play an important role in signal transduction by modulating clustering and dynamics of membrane receptors. Changes in lipid composition are therefore likely to influence receptor organisation and function, but how this precisely occurs is difficu...

journal_title：Scientific reports

authors： Eich C,Manzo C,de Keijzer S,Bakker GJ,Reinieren-Beeren I,García-Parajo MF,Cambi A

更新日期：2016-02-12 00:00:00

abstract：:Spatially-resolved neutron powder diffraction with a gauge volume of 2 × 2 × 20 mm(3) has been applied as an in situ method to probe the lithium concentration in the graphite anode of different Li-ion cells of 18650-type in charged state. Structural studies performed in combination with electrochemical measurements an...

journal_title：Scientific reports

authors： Senyshyn A,Mühlbauer MJ,Dolotko O,Hofmann M,Ehrenberg H

更新日期：2015-12-18 00:00:00

abstract：:The goal of this work was to develop a mathematical model to predict Kaplan-Meier survival curves for chemotherapy combined with radiation in Non-Small Cell Lung Cancer patients for use in clinical trial design. The Gompertz model was used to describe tumor growth, radiation effect was simulated by the linear-quadrati...

journal_title：Scientific reports

authors： Geng C,Paganetti H,Grassberger C

更新日期：2017-10-19 00:00:00

abstract：:The auditory steady-state response (ASSR) has been used to detect auditory processing deficits in patients with psychiatric disorders. However, the methodology of ASSR recording from the brain surface has not been standardized in preclinical studies, limiting its use as a translational biomarker. The sites of maximal ...

journal_title：Scientific reports

authors： Kozono N,Honda S,Tada M,Kirihara K,Zhao Z,Jinde S,Uka T,Yamada H,Matsumoto M,Kasai K,Mihara T

更新日期：2019-06-11 00:00:00

abstract：:Multicolor microscopy tools necessary to localize and visualize the complexity of subcellular systems are limited by current fluorophore technology. While commercial fluorophores cover spectral space from the ultraviolet to the near infrared region and are optimized for conventional bandpass based fluorescence microsc...

journal_title：Scientific reports

authors： Bittel AM,Davis AM,Wang L,Nederlof MA,Escobedo JO,Strongin RM,Gibbs SL

更新日期：2018-03-15 00:00:00