A quantitative analysis of 3D-cell distribution in regenerating muscle-skeletal system with synchrotron X-ray computed microtomography.

abstract：:Early detection of cancer is essential for effective intervention. Urine has been used to reflect early changes in various tumor-bearing models. However, urine has not been used to predict whether tumors will form in animal models. In this study, a cancer model was established by tail vein injection of 2 million NuTu-...

journal_title：Scientific reports

authors： Wei J,Ni N,Meng W,Huan Y,Gao Y

更新日期：2020-07-16 00:00:00

abstract：:Transcriptome diversity in adult neurons is partly mediated by RNA binding proteins (RBPs), including the RBFOX factors. RBFOX3/NeuN, a neuronal maturity marker, is strangely depleted in suprachiasmatic nucleus (SCN) neurons, and may be compensated by a change in Rbfox2 expression. In this study, we found no superfici...

journal_title：Scientific reports

authors： Partridge LMM,Carter DA

更新日期：2017-08-30 00:00:00

abstract：:Sea level rise (SLR) will cause shoreline retreat of sandy coasts in the absence of sand supply mechanisms. These coasts have high touristic and ecological value and provide protection of valuable infrastructures and buildings to storm impacts. So far, large-scale assessments of shoreline retreat use specific datasets...

journal_title：Scientific reports

authors： Athanasiou P,van Dongeren A,Giardino A,Vousdoukas MI,Ranasinghe R,Kwadijk J

更新日期：2020-07-17 00:00:00

abstract：:Phytophthora blight is one of the most serious diseases affecting melon (Cucumis melo) production. Due to the lack of highly resistant germplasms, the progress on disease-resistant research is slow. To understand the genetics of melon resistance to Phytophthora capsici, an F2 population containing 498 individuals was ...

journal_title：Scientific reports

authors： Wang P,Xu X,Zhao G,He Y,Hou C,Kong W,Zhang J,Liu S,Xu Y,Xu Z

更新日期：2020-11-24 00:00:00

abstract：:Functionalization of monoclonal antibodies (mAbs) requires chemical derivatization and/or genetic manipulation. Inherent in these methods are challenges with protein heterogeneity, stability and solubility. Such perturbations could potentially be avoided by using a high affinity, non-covalent intermediate to bridge th...

journal_title：Scientific reports

authors： Avery KN,Zer C,Bzymek KP,Williams JC

更新日期：2015-01-15 00:00:00

abstract：:The N-methyl-D-aspartate subfamily of ionotropic glutamate receptors (NMDARs) is well known for its important roles in the central nervous system (CNS), e.g. learning and memory formation. Besides the CNS, NMDARs are also expressed in numerous peripheral tissues including the pancreas, kidney, stomach, and blood cells...

journal_title：Scientific reports

authors： Koch A,Bonus M,Gohlke H,Klöcker N

更新日期：2019-07-11 00:00:00

abstract：:Recovery of nutrients and energy from municipal wastewater has attracted much attention in recent years; however, its efficiency is significantly limited by the low-strength properties of municipal wastewater. Herein, we report a pilot-scale forward osmosis (FO) system using a spiral-wound membrane module to concentra...

journal_title：Scientific reports

authors： Wang Z,Zheng J,Tang J,Wang X,Wu Z

更新日期：2016-02-22 00:00:00

abstract：:Radiotherapy can result in lung diseases pneumonitis or fibrosis dependent on patient susceptibility. Herein we used inbred and genetically altered mice to investigate whether the tissue adaptive immune response to radiation injury influences the development of radiation-induced lung disease. Six inbred mouse strains ...

journal_title：Scientific reports

authors： Paun A,Bergeron ME,Haston CK

更新日期：2017-09-14 00:00:00

abstract：:Infantile hemangioma is the most common benign tumor in infants. Many studies have confirmed that basic fibroblast growth factor (bFGF) and its key receptor FGFR1 are highly expressed in hemangioma. Moreover, several miRNAs can regulate angiogenesis. In this regard, miR-424 often plays a role as tumor suppressor gene....

journal_title：Scientific reports

authors： Yang L,Dai J,Li F,Cheng H,Yan D,Ruan Q

更新日期：2017-09-19 00:00:00

abstract：:Urothelial cells play essential roles in protection of urine exudation and bacterial invasion at the urothelial mucosa, so that defect or damage of urothelial cells associated with urinary tract diseases may cause serious problems. If a sufficient number of functional urothelial cells are prepared in culture and trans...

journal_title：Scientific reports

authors： Inoue Y,Kishida T,Kotani SI,Akiyoshi M,Taga H,Seki M,Ukimura O,Mazda O

更新日期：2019-09-25 00:00:00

abstract：:Surface enhanced Raman scattering (SERS) is generally and widely used to enhance the vibrational fingerprint of molecules located at the vicinity of noble metal nanoparticles. In this work, SERS is originally used to enhance the own vibrational density of states (VDOS) of nude and isolated gold nanoparticles. This off...

journal_title：Scientific reports

authors： Carles R,Benzo P,Pécassou B,Bonafos C

更新日期：2016-12-16 00:00:00

abstract：:Huntington's disease (HD) is a neurodegenerative disorder whose major symptoms include progressive motor and cognitive dysfunction. Cognitive decline is a critical quality of life concern for HD patients and families. The enzyme histone deacetylase 3 (HDAC3) appears to be important in HD pathology by negatively regula...

journal_title：Scientific reports

authors： Suelves N,Kirkham-McCarthy L,Lahue RS,Ginés S

更新日期：2017-07-20 00:00:00

abstract：:Monitoring marine top predators is fundamental for assessing the health and functioning of open ocean ecosystems. Although recently tracking observations have substantially increased, factors determining the horizontal exploration of the ocean by marine predators are still largely unknown, especially at the scale of b...

journal_title：Scientific reports

authors： Della Penna A,De Monte S,Kestenare E,Guinet C,d'Ovidio F

更新日期：2015-12-15 00:00:00

abstract：:The endogenous circadian clock drives oscillations that are completely synchronized with the environmental day-night rhythms with a period of approximately 24 hours. Temporal misalignment between one's internal circadian clock and the external solar time often occurs in shift workers and long-distance travelers; such ...

journal_title：Scientific reports

authors： Kori H,Yamaguchi Y,Okamura H

更新日期：2017-04-26 00:00:00

abstract：:Nuclear proteins are primarily regulatory factors governing gene expression. Multiple factors determine the localization of a protein in the nucleus. An upright identification of nuclear proteins is way far from accuracy. We have attempted to combine information from subcellular prediction tools, experimental evidence...

journal_title：Scientific reports

authors： Deveshwar P,Sharma S,Prusty A,Sinha N,Zargar SM,Karwal D,Parashar V,Singh S,Tyagi AK

更新日期：2020-09-15 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Delplancke TDJ,de Seymour JV,Tong C,Sulek K,Xia Y,Zhang H,Han TL,Baker PN

更新日期：2020-02-21 00:00:00

abstract：:Plants experience a highly variable light environment over the course of the day. To reveal the molecular mechanisms of their photosynthetic response to fluctuating light, we examined the role of two cyclic electron flows around photosystem I (CEF-PSI)--one depending on PROTON GRADIENT REGULATION 5 (PGR5) and one on N...

journal_title：Scientific reports

authors： Yamori W,Makino A,Shikanai T

更新日期：2016-02-02 00:00:00

abstract：:Soil physical properties and soil organic carbon (SOC) are considered as important factors of soil quality. Arable land, grassland, and forest land coexist in the saline-alkali reclamation area of the Yellow River Delta (YRD), China. Such different land uses strongly influence the services of ecosystem to induce soil ...

journal_title：Scientific reports

authors： Jiao S,Li J,Li Y,Xu Z,Kong B,Li Y,Shen Y

更新日期：2020-11-23 00:00:00

abstract：:Microbiologically Influenced Corrosion (MIC) is a serious problem in many industries because it causes huge economic losses. Due to its excellent resistance to chemical corrosion, 2707 hyper duplex stainless steel (2707 HDSS) has been used in the marine environment. However, its resistance to MIC was not experimentall...

journal_title：Scientific reports

authors： Li H,Zhou E,Zhang D,Xu D,Xia J,Yang C,Feng H,Jiang Z,Li X,Gu T,Yang K

更新日期：2016-02-05 00:00:00

abstract：:The aberrant expression of human sodium iodide symporter (NIS) in breast cancer (BC) has raised the possibility of using targeted radioiodide therapy. Here we investigate modulation of endogenous, functional NIS expression by histone deacetylase inhibitors (HDACi) in vitro and in vivo. Luciferase reporter based initia...

journal_title：Scientific reports

authors： Kelkar MG,Senthilkumar K,Jadhav S,Gupta S,Ahn BC,De A

更新日期：2016-01-18 00:00:00

abstract：:Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engineering. Extrusion-based 3D bioprinting necessitates a phase change from a liquid bioink to a semi-solid crosslinked network achieved by a photo-initiated free radical polymerization reaction that is known to be cytotox...

journal_title：Scientific reports

authors： Duchi S,Onofrillo C,O'Connell CD,Blanchard R,Augustine C,Quigley AF,Kapsa RMI,Pivonka P,Wallace G,Di Bella C,Choong PFM

更新日期：2017-07-19 00:00:00

abstract：:We summarized published data on the associations of apolipoprotein E (APOE) gene ε2/ε3/ε4 polymorphism with both cancer risk and circulating lipid profiles, aiming to examine the causal relevance between lipids and cancer risk. Article identification and data abstraction were conducted in duplicate and independently b...

journal_title：Scientific reports

authors： Yang C,Tian G,Mi J,Wei X,Li X,Li X,Wang W,Wang B

更新日期：2015-03-30 00:00:00

abstract：:The abundance and diversity of bacteria in two types of ponds were investigated by quantitative PCR and Illumina MiSeq sequencing. The results revealed that the abundance of bacterial 16S rRNA genes in D ponds (with grass carp fed sudan grass) was significantly lower than that in E ponds (with grass carp fed commercia...

journal_title：Scientific reports

authors： Qin Y,Hou J,Deng M,Liu Q,Wu C,Ji Y,He X

更新日期：2016-10-19 00:00:00

abstract：:Polarization control using single plasmonic nanoantennas is of interest for subwavelength optical components in nano-optical circuits and metasurfaces. Here, we investigate the role of two mechanisms for polarization conversion by plasmonic antennas: Structural asymmetry and plasmon hybridization through strong coupli...

journal_title：Scientific reports

authors： Wiecha PR,Black LJ,Wang Y,Paillard V,Girard C,Muskens OL,Arbouet A

更新日期：2017-01-19 00:00:00

abstract：:Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within their genomic stru...

journal_title：Scientific reports

authors： Lam TH,Tay MZ,Wang B,Xiao Z,Ren EC

更新日期：2015-11-23 00:00:00

abstract：:Epigallocatechin-3-gallate (EGCG), a green tea-derived polyphenol, exhibits antitumor activities. An EGCG nanoemulsion (nano-EGCG) was prepared to improve the stability and reduce the side effects of EGCG for treatment of human lung cancer cells, and the antitumor effects were studied. The possible molecular mechanism...

journal_title：Scientific reports

authors： Chen BH,Hsieh CH,Tsai SY,Wang CY,Wang CC

更新日期：2020-03-20 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is a low-grade chronic inflammatory diseases, which have been implicated in the pathogenesis of cognitive decline. We aim to evaluate associations between inflammatory markers and the risk of mild cognitive impairment (MCI) in T2DM. This study of 140 diabetic patients involved 71 with M...

journal_title：Scientific reports

authors： Cai R,Huang R,Han J,Sun H,Sun J,Xia W,Tian S,Dong X,Shen Y,Wang S

更新日期：2017-09-26 00:00:00

abstract：:The present study aimed to explore a new source of montmorillonite and to develop an extraction and purification protocol for its isolation from raw clay samples acquired from the Koh-e-Suleiman mountain range in Pakistan. The process involved the collection of raw clay from the source, identification and quantificati...

journal_title：Scientific reports

authors： Nirwan JS,Farhaj S,Chaudhary MM,Khizer Z,Hasan SS,Angelis-Dimakis A,Gill A,Rasheed H,Abbas N,Arshad MS,Hussain T,Shahzad Y,Yousaf AM,Chohan TA,Hussain T,Merchant HA,Akram MR,Khan TM,Ashraf M,Conway BR,Ghori MU

更新日期：2020-01-17 00:00:00

abstract：:Owing to their unique optical properties such as large absorption and scattering cross section and large enhancement of electromagnetic field at the surface, plasmonic nanostructures have received extensive attention as a highly promising class of materials for nano-oncology. Most of the existing plasmonic nanostructu...

journal_title：Scientific reports

authors： Gandra N,Portz C,Nergiz SZ,Fales A,Vo-Dinh T,Singamaneni S

更新日期：2015-05-14 00:00:00

abstract：:Concurrent chemoradiation therapy (CCRT) is the treatment of choice for locally advanced non-small cell lung cancer (LA-NSCLC). Several clinical trials that combine programmed cell death 1 (PD-1) axis inhibitors with radiotherapy are in development for patients with LA-NSCLC. However, the effect of CCRT on programmed ...

journal_title：Scientific reports

authors： Fujimoto D,Uehara K,Sato Y,Sakanoue I,Ito M,Teraoka S,Nagata K,Nakagawa A,Kosaka Y,Otsuka K,Imai Y,Hamakawa H,Takahashi Y,Kokubo M,Tomii K

更新日期：2017-09-12 00:00:00