Abstract:
AIM:Early Intervention Psychosis Services (EIPS) for people experiencing First Episode Psychosis (FEP) offer important clinical and non-clinical benefits over standard care. Similarly, intervention for Clinical High Risk for Psychosis state (CHR-P) can prevent psychosis, ameliorate symptoms and have non-clinical benefits. This study aimed to estimate associated local economic benefits of FEP and CHR-P services compared with standard care. METHODS:Across four south London boroughs, proportion of annual number of new cases of FEP and CHR-P seen by early intervention services was estimated. Economic modelling conducted for England's mental health strategy was applied to estimate local economic impacts of current and improved service provision. RESULTS:Across four London boroughs during 2011/2012, proportion of 15-34 year olds with FEP seen by EIPS was 100.2% assuming 80/100 000 annual incidence whereas proportion with CHR-P seen by CHR-P services was 4.1% assuming 200/100 000 annual incidence. Application of economic modelling suggests that provision of EIPS to reach all new FEP cases each year would free up resources of £13.1m over 10 years including £2.0m to National Health Service (NHS) after the first year. Scaling up to reach all new CHR-P cases each year would free up resources of £19.7m over 10 years with an estimated 10-year cost of implementation gap for each 1 year cohort of £18.9m. An earlier related briefing resulted in increased funding for EIPS and new CHR-P services despite overall cuts to mental health services. CONCLUSIONS:Estimation of local economic impacts of FEP and CHR-P services was associated with improved investment in such services.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Campion J,Taylor MJ,McDaid D,Park AL,Shiers Ddoi
10.1111/eip.12787subject
Has Abstractpub_date
2019-12-01 00:00:00pages
1424-1430issue
6eissn
1751-7885issn
1751-7893journal_volume
13pub_type
杂志文章abstract:AIM:Reduced social network (SN) might be associated with a longer duration of untreated psychosis (DUP) in people with first episode psychosis (FEP). We aimed at exploring the specific role of SN confidants on DUP, taking into account cannabis misuse, which is known to influence DUP and might be associated with social ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12476
更新日期:2018-10-01 00:00:00
abstract:AIM:To determine the association between duration of untreated psychosis (DUP) and symptoms remission in a hospitalized first-episode psychosis cohort. METHODS:Inpatients with a first-episode non-affective psychosis were recruited. Subjects were divided into two groups of long and short DUP using a 3-month cut-off poi...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12266
更新日期:2017-02-01 00:00:00
abstract:AIM:Suicidal behaviours (suicide attempts and suicides) are common among individuals experiencing, or having recently experienced, a first-episode psychosis (FEP). Current interventions for suicidal behaviours are crisis driven and focused on hospital admission of patients at imminent risk of ending their lives. This p...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12084
更新日期:2014-11-01 00:00:00
abstract:AIM:Valid instruments for the early identification of psychotic experiences (PE) and symptoms in youths are urgently needed for large-scale preventive interventions. A new section of The-Development-and-Well-Being Assessment (DAWBA) measuring child self-reported PE has yet to be validated. The current study aimed to in...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12547
更新日期:2019-06-01 00:00:00
abstract:AIM:To determine duration of untreated psychosis (DUP) in patients with schizophrenia-spectrum disorders from Serbia and to analyse factors that potentially contribute to the treatment delay, with focus on personality traits. METHODS:Fifty seven patients (males 54.4%; age = 29.9 ± 6.0 yrs; age at the illness onset = 2...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12348
更新日期:2018-02-01 00:00:00
abstract:AIM:To design and assess the psychometric properties of a questionnaire to identify and measure factors that influence the identification of individuals at ultra-high risk for psychosis in primary care. It will inform the subsequent design of educational interventions to help general practitioners (GPs; primary care ph...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00296.x
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Both the nature and number of a wide range of prodromal symptoms have been related to the severity and type of psychopathology in the psychotic phase. However, at present there is an incomplete picture focused mainly on the positive pre-psychotic dimension. AIM:To characterize the prodromal phase retrospect...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12498
更新日期:2019-06-01 00:00:00
abstract:AIM:Ultrahigh risk (UHR) criteria, consisting of brief limited intermittent psychotic symptoms (BLIPS), attenuated psychotic symptoms (APS) and genetic risk and deterioration (GRD) syndrome are the most widely used criteria for assessing the clinical high-risk state for psychosis (CHR-P). The Basel Screening Instrument...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12719
更新日期:2019-08-01 00:00:00
abstract:AIM:Prior to the release of the fifth edition of the Diagnostic and Statistical Manual for Mental Disorders, experts in the field of psychosis research considered including a psychosis high-risk syndrome-attenuated psychosis syndrome-as a formal diagnosis. Opponents argued that such a diagnosis may increase the risk of...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12710
更新日期:2019-08-01 00:00:00
abstract:AIM:It is now necessary to investigate whether recovery in psychosis is possible without the use of antipsychotic medication. This study will determine (1) whether a first-episode psychosis (FEP) group receiving intensive psychosocial interventions alone can achieve symptomatic remission and functional recovery; (2) wh...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1111/eip.12716
更新日期:2019-08-01 00:00:00
abstract:AIM:Neurophysiological markers of schizophrenia may help identify individuals who are at an increased risk of developing psychosis. As an operational measure of sensorimotor gating, pre-pulse inhibition (PPI) deficit has been investigated in clinical high-risk (CHR) individuals. In this study, we performed a systematic...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13015
更新日期:2020-07-24 00:00:00
abstract:AIM:This paper aims to identify the ways in which youth at ultra high risk for psychosis access mental health services and the factors that advance or delay help seeking, using the Revised Network Episode Model (REV NEM) of mental health care. METHODS:A case study approach documents help-seeking pathways, encompassing...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2012.00350.x
更新日期:2013-05-01 00:00:00
abstract:AIM:This study aimed to explore the presence of psychotic like experience (PLE) symptoms and evaluate for the possible socio-demographic, family, school and mental health variables associated with clinically significant PLE symptoms in Nigeria school adolescent. METHODS:A total of 9441 adolescents from 47 secondary sc...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13032
更新日期:2020-09-02 00:00:00
abstract:AIM:This study aims to evaluate the outcomes and economic case for a UK innovative youth-specific mental health service for 16-25 year olds. METHODS:A pre-, during- and post-treatment comparative design for 20 young people at high risk of developing psychosis who received 2 years' treatment with the service, using out...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12261
更新日期:2017-10-01 00:00:00
abstract:AIM:Early-onset schizophrenia (onset before adulthood) is a rare and severe form of the disorder that shows phenotypic and neurobiological continuity with adult-onset schizophrenia. Here, we provide a synthesis of keynote findings in this enriched population to understand better the neurobiology and pathophysiology of ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/j.1751-7893.2010.00253.x
更新日期:2011-02-01 00:00:00
abstract:AIM:In this study, we investigate the feasibility and acceptability of a 9-month psychoeducational multi-family group (PMFG) intervention for adolescents who are at ultra-high-risk (UHR) for developing psychosis. METHODS:The treatment programme was adapted from those previously shown to be effective in patients with e...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2007.00046.x
更新日期:2007-11-01 00:00:00
abstract:AIM:It has been found that long-chain omega-3 polyunsaturated fatty acids (PUFAs) reduce the risk of progression to first episode of psychosis (FEP) and may offer a safe and efficacious strategy for selective and indicated prevention in young people with ultra-high-risk (UHR) states. An opportunity for exploring the tr...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1111/eip.12197
更新日期:2016-10-01 00:00:00
abstract:AIM:Early intervention in eating disorders (EDs) has been a neglected area. Peak onset is in adolescence, suggesting that early intervention should include parents. We synthesize findings from five key theoretical domains, and present pilot data from a phase-specific early intervention for new onset EDs in young people...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/j.1751-7893.2012.00373.x
更新日期:2012-11-01 00:00:00
abstract:AIM:Improvement of social adjustment is a major aim of indicated prevention in young people at risk of developing psychosis. The present study explores the effect of specific cognitive behaviour therapy (CBT) as compared with supportive counselling (SC) on social adjustment in people in a potential early initial prodro...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1751-7893.2007.00013.x
更新日期:2007-02-01 00:00:00
abstract:AIMS:To review intervention variables and outcomes of studies designed to increase physical activity or exercise participation among people experiencing first-episode psychosis. METHODS:A systematic review of electronic databases was conducted from inception to November 2014. RESULTS:Eleven eligible studies describin...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/eip.12238
更新日期:2016-10-01 00:00:00
abstract:AIM:Looking after someone in the early stages of psychosis can have a negative impact on caregivers, but there is little clarity about which interventions, if any, caregivers should be offered. This study investigated sleep disturbances in early psychosis caregivers and the relationship between their sleep quality and ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12538
更新日期:2019-06-01 00:00:00
abstract:AIMS:Depression in adolescents is common and debilitating. Treatment approaches vary widely across clinics and may not reflect evidence-based care. Integrated care pathways (ICPs) are implementation tools to facilitate bridging the gap between rigorous but often complex clinical practice guidelines and what is actually...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12918
更新日期:2020-08-01 00:00:00
abstract:AIMS:This study aimed to develop a comprehensive measurement tool for assessing client satisfaction at a youth mental health service. METHODS:We developed a scale based on existing scale items and by generating new items, before undertaking revisions and item reduction in consultation with an expert panel composed of ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12104
更新日期:2014-11-01 00:00:00
abstract:AIM:Depression and suicidal ideation (SUI) and behaviour are more prevalent in females than males, and common in clinical high-risk (CHR) patients. Childhood adversities and trauma (CAT) are associated with adult depression and SUI. The role of gender as a moderator and depression as a mediator for the effect of CAT on...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12714
更新日期:2019-08-01 00:00:00
abstract:AIMS:Most programs specializing in the treatment of first-episode psychosis in the United States focus on schizophrenia. However, many early psychosis patients do not fit into this diagnostic category. Here we describe McLean OnTrack, an intensive outpatient treatment program that accepts all comers with first-episode ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12299
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Approximately 80 000 children and young people in the UK suffer from depression, but many are untreated because of poor identification of early warning signs and risk factors. AIMS:This study aimed to derive and to investigate discrimination characteristics of a prediction model for a first recorded diagnos...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12332
更新日期:2018-06-01 00:00:00
abstract:AIM:Cognitive and functioning impairments are present early in the course of psychotic disorder and remain one of the greatest treatment challenges. Cognitive adaptation training (CAT) is a compensatory approach to psychosocial intervention that is underpinned by a model that incorporates the role of cognition in daily...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12207
更新日期:2016-12-01 00:00:00
abstract:AIM:Most studies on the determinants of psychosocial functioning in first-episode psychosis used few predictors. This study examines the effects of multiple cognitive domains and multiple symptoms on psychosocial functioning. METHODS:A total of 162 patients with a first-episode psychosis were assessed within 3 months ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12210
更新日期:2017-02-01 00:00:00
abstract:AIM:Thought disorder is a core feature of schizophrenia but assessment of disordered thinking is challenging, which may contribute to the paucity of mechanistic understanding of disorganization in early psychosis. We studied the use of linguistic connectives in relation to clinically quantified dimensions of thought di...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12948
更新日期:2020-03-03 00:00:00
abstract:AIM:To increase our understanding of substance use among adolescents with psychosis by comparing their reasons for use with those of typically developing adolescents. METHODS:Participants were 35 outpatient adolescents, recently admitted for a first episode of psychosis to an early psychosis programme, and 35 typicall...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2007.00055.x
更新日期:2008-02-01 00:00:00