Duration of untreated psychosis and acute remission of negative symptoms in a South American first-episode psychosis cohort.

Abstract:

AIM:To determine the association between duration of untreated psychosis (DUP) and symptoms remission in a hospitalized first-episode psychosis cohort. METHODS:Inpatients with a first-episode non-affective psychosis were recruited. Subjects were divided into two groups of long and short DUP using a 3-month cut-off point, and this was related to remission at 10 weeks of treatment. Multivariate analyses were performed. RESULTS:Fifty-five inpatients were included. There were no differences in remission rates of positive symptoms. Up to 76.5% of the patients with a short DUP (<3 months) achieved remission of negative symptoms versus 31.6% in the DUP ≥ 3 months group (P = 0.003). After controlling for relevant factors, patients with a shorter DUP were still three times more likely to achieve negative symptoms remission (HR: 3.04, 95% CI 1.2-7.5). CONCLUSIONS:DUP is a prognostic factor that should be considered at an early stage to identify a 'high risk' subgroup of persistent negative symptoms.

authors

González-Valderrama A,Castañeda CP,Mena C,Undurraga J,Mondaca P,Yañez M,Bedregal P,Nachar R

doi

10.1111/eip.12266

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

77-82

issue

1

eissn

1751-7885

issn

1751-7893

journal_volume

11

pub_type

杂志文章
  • Social network confidants, duration of untreated psychosis and cannabis use in people with first episode psychosis: An exploratory study.

    abstract:AIM:Reduced social network (SN) might be associated with a longer duration of untreated psychosis (DUP) in people with first episode psychosis (FEP). We aimed at exploring the specific role of SN confidants on DUP, taking into account cannabis misuse, which is known to influence DUP and might be associated with social ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12476

    authors: Carrà G,Battaglia C,Hinton M,Sheridan Rains L,Crocamo C,Johnson S

    更新日期:2018-10-01 00:00:00

  • MAKINGtheLINK: a school-based health promotion programme to increase help-seeking for cannabis and mental health issues among adolescents.

    abstract:AIM:There is increasing concern regarding the use of cannabis among adolescents, especially given recent evidence highlighting its link with later mental disorders. Encouraging young people with mental health or drug issues to seek professional help is an important early intervention strategy; however, adolescents are ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2010.00252.x

    authors: Berridge BJ,Hall K,Dillon P,Hides L,Lubman DI

    更新日期:2011-02-01 00:00:00

  • Teachers' awareness for psychotic symptoms in secondary school: the effects of an early detection programme and information campaign.

    abstract:AIM:The objective of the study was to investigate high school teacher's literacy on psychosis symptoms and teachers' confidence in the positive effects of psychosis treatment on the mental health of students with psychotic symptoms at two sites: one site with an extensive early detection of psychosis programme includin...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2010.00248.x

    authors: Langeveld J,Joa I,Larsen TK,Rennan JA,Cosmovici E,Johannessen JO

    更新日期:2011-05-01 00:00:00

  • Perceptual abnormalities in an ultra-high risk for psychosis population relationship to trauma and co-morbid disorder.

    abstract:AIMS:The aims of this study were 3-fold. We wished to investigate whether at baseline entry to an ultra-high risk (UHR) clinic whether: (1) perceptual abnormalities are more prevalent in those young people with co-morbid psychiatric diagnoses, (2) perceptual abnormalities are more prevalent in those young people with h...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12469

    authors: O' Connor K,Nelson B,Cannon M,Yung A,Thompson A

    更新日期:2019-04-01 00:00:00

  • Suicidal behaviours during treatment for first-episode psychosis: towards a comprehensive approach to service-based prevention.

    abstract:AIM:Suicidal behaviours (suicide attempts and suicides) are common among individuals experiencing, or having recently experienced, a first-episode psychosis (FEP). Current interventions for suicidal behaviours are crisis driven and focused on hospital admission of patients at imminent risk of ending their lives. This p...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12084

    authors: Fedyszyn IE,Robinson J,Harris MG,Paxton SJ,Francey S,Edwards J

    更新日期:2014-11-01 00:00:00

  • Gender differences in first self-perceived signs and symptoms in patients with an at-risk mental state and first-episode psychosis.

    abstract:AIM:Gender differences in the current symptomatology of patients with psychotic disorders have previously been described in the literature. However, it has not yet been investigated whether gender differences exist in the very first self-perceived signs or symptoms of illness onset. The aim of this study was to investi...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12528

    authors: Heitz U,Studerus E,Menghini-Müller S,Papmeyer M,Egloff L,Ittig S,Navarra A,Andreou C,Riecher-Rössler A

    更新日期:2019-06-01 00:00:00

  • Filling the implementation gap: a community-academic partnership approach to early intervention in psychosis.

    abstract:AIM:The aim of this study was to describe the development of a sustainable community early psychosis programme created through an academic-community partnership in the United States to other parties interested in implementing early psychosis services founded upon evidence-based practices within community settings. MET...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2011.00310.x

    authors: Hardy KV,Moore M,Rose D,Bennett R,Jackson-Lane C,Gause M,Jackson A,Loewy R

    更新日期:2011-11-01 00:00:00

  • Roles of peer specialists and use of mental health services among youth with serious mental illness.

    abstract:AIM:To examine whether roles of peer specialists affect service use among Black, Latinx and White youth ages 16-24 with serious mental illness (SMI) in Los Angeles and San Diego Counties. METHODS:Administrative data from 2015 to 2018 was used to summarize service use among 6329 transition age youth age 16-24 with SMI ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.13036

    authors: Ojeda VD,Jones N,Munson MR,Berliant E,Gilmer TP

    更新日期:2020-09-04 00:00:00

  • Initial medical work-up of first-episode psychosis: a conceptual review.

    abstract:AIM:To help clinicians carry out a comprehensive, medical diagnostic assessment in first-episode patients who are suspected of developing schizophrenia. METHODS:Conceptual review of the published work with emphasis on the diagnostic goals of excluding medical causes of psychosis and establishing a medical baseline. R...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1111/j.1751-7893.2008.00105.x

    authors: Freudenreich O,Schulz SC,Goff DC

    更新日期:2009-02-01 00:00:00

  • Feasibility and acceptability of a volunteer peer fidelity assessment model in early psychosis intervention programmes in Ontario: Results from a pilot study.

    abstract:AIM:Fidelity monitoring can support high-quality service delivery but is resource-intensive to implement. A fidelity assessment model utilizing volunteer assessors was trialled as a low-cost strategy for conducting fidelity assessments. This article reports on the acceptability and feasibility of this model. METHODS:T...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12961

    authors: Selick A,Langill G,Cheng C,Addington D,Archie S,Butt S,Durbin J

    更新日期:2020-03-31 00:00:00

  • Negative symptoms of psychosis: A life course approach and implications for prevention and treatment.

    abstract:AIM:Negative symptoms are a cause of enduring disability in serious mental illness. In spite of this, the development of effective treatments for negative symptoms has remained slow. The challenge of improving negative symptom outcomes is compounded by our limited understanding of their aetiology and longitudinal devel...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1111/eip.12501

    authors: Lyne J,O'Donoghue B,Roche E,Renwick L,Cannon M,Clarke M

    更新日期:2018-08-01 00:00:00

  • Specialized, multi-component care for individuals with first-episode psychosis: Effects on autonomy, competence and relatedness.

    abstract:AIM:Self-determination theory (SDT) has demonstrated that human well-being is associated with the satisfaction of three basic psychological needs (ie, autonomy, competence and relatedness)-with more recent research highlighting the applicability of SDT to individuals with first-episode psychosis (FEP). These findings s...

    journal_title:Early intervention in psychiatry

    pub_type: 临床试验,杂志文章

    doi:10.1111/eip.12784

    authors: Breitborde NJK,Pine JG,Moe AM

    更新日期:2019-12-01 00:00:00

  • "If you don't speak from the heart, the young mob aren't going to listen at all": An invitation for youth mental health services to engage in new ways of working.

    abstract:AIM:Aboriginal and Torres Strait Islander young people are more likely to experience mental health issues or end their life by suicide than non-Aboriginal youth, but are less likely to access mental health services for support. Systemic change is required if mainstream youth mental health services are to be relevant an...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12844

    authors: Wright M,Culbong T,Crisp N,Biedermann B,Lin A

    更新日期:2019-12-01 00:00:00

  • Evaluation of a professional development training programme for mental health clinicians specializing in early psychosis.

    abstract::The Early Psychosis Prevention and Intervention Centre Statewide Services (ESW) team provides training for multidisciplinary clinicians that specialise in early psychosis across the State of Victoria, Australia. The aim of this paper is to describe the 4-phase approach utilised by ESW to prepare for and deliver worksh...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12424

    authors: Macneil C,Foster F,Nicoll A,Osman H,Monfries R,Cotton S

    更新日期:2018-06-01 00:00:00

  • Exploratory comparison of auditory verbal hallucinations and other psychotic symptoms among youth with borderline personality disorder or schizophrenia spectrum disorder.

    abstract:OBJECTIVE:This study explored phenomenological aspects of auditory verbal hallucinations (AVH) and other psychotic symptoms among youth with borderline personality disorder (BPD). METHODS:Sixty-eight outpatients, aged 15 to 25 years, were categorized into three groups according to their primary Diagnostic and Statisti...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12763

    authors: Cavelti M,Thompson KN,Hulbert C,Betts J,Jackson H,Francey S,Homan P,Chanen AM

    更新日期:2019-10-01 00:00:00

  • The role of youth mental health services in the treatment of young people with serious mental illness: 2-year outcomes and economic implications.

    abstract:AIM:This study aims to evaluate the outcomes and economic case for a UK innovative youth-specific mental health service for 16-25 year olds. METHODS:A pre-, during- and post-treatment comparative design for 20 young people at high risk of developing psychosis who received 2 years' treatment with the service, using out...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12261

    authors: Brimblecombe N,Knapp M,Murguia S,Mbeah-Bankas H,Crane S,Harris A,Evans-Lacko S,Ardino V,Iemmi V,King D

    更新日期:2017-10-01 00:00:00

  • Treating young individuals at clinical high risk for psychosis.

    abstract:BACKGROUND:Typically, studies investigating those at clinical high risk for psychosis have focused on predictors of conversion and treatments that might prevent conversion to full-blown psychosis. Few studies have followed those who do not go on to develop a psychotic illness. METHODS:Participants were 48 young people...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1751-7893.2011.00299.x

    authors: Marshall C,Addington J,Epstein I,Liu L,Deighton S,Zipursky RB

    更新日期:2012-02-01 00:00:00

  • Childhood physical neglect and psychotic experiences: Findings from the National Comorbidity Survey Replication.

    abstract:AIM:Childhood adversities have been linked to an increased risk for psychosis. However, as yet, there has been comparatively little research on the effects of neglect. This study examined the association between childhood physical neglect and psychotic experiences (PEs) in a general population sample. METHODS:Data wer...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12932

    authors: Stickley A,Waldman K,Sumiyoshi T,Narita Z,Shirama A,Shin JI,Oh H

    更新日期:2020-02-11 00:00:00

  • Derivation of a prediction model for a diagnosis of depression in young adults: a matched case-control study using electronic primary care records.

    abstract:BACKGROUND:Approximately 80 000 children and young people in the UK suffer from depression, but many are untreated because of poor identification of early warning signs and risk factors. AIMS:This study aimed to derive and to investigate discrimination characteristics of a prediction model for a first recorded diagnos...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12332

    authors: Nichols L,Ryan R,Connor C,Birchwood M,Marshall T

    更新日期:2018-06-01 00:00:00

  • Indicated prevention with long-chain polyunsaturated omega-3 fatty acids in patients with 22q11DS genetically at high risk for psychosis. Protocol of a randomized, double-blind, placebo-controlled treatment trial.

    abstract:AIM:It has been found that long-chain omega-3 polyunsaturated fatty acids (PUFAs) reduce the risk of progression to first episode of psychosis (FEP) and may offer a safe and efficacious strategy for selective and indicated prevention in young people with ultra-high-risk (UHR) states. An opportunity for exploring the tr...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/eip.12197

    authors: Armando M,De Crescenzo F,Vicari S,Digilio MC,Pontillo M,Papaleo F,Amminger GP

    更新日期:2016-10-01 00:00:00

  • Early intervention and identification strategies for young people at risk of developing mental health issues: working in partnership with schools in Birmingham, UK.

    abstract:AIM:This study explores the mental health needs of teachers and how these might impact on their capacity to provide early identification and intervention strategies to support their student's emotional well-being. METHOD:The present study surveyed a sample of UK teachers (N = 320) to explore the impact of work-related...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12264

    authors: Palmer CJ,Connor C,Newton BJ,Patterson P,Birchwood M

    更新日期:2017-12-01 00:00:00

  • Openness to experience shortens duration of untreated psychosis in Serbian clinical population.

    abstract:AIM:To determine duration of untreated psychosis (DUP) in patients with schizophrenia-spectrum disorders from Serbia and to analyse factors that potentially contribute to the treatment delay, with focus on personality traits. METHODS:Fifty seven patients (males 54.4%; age = 29.9 ± 6.0 yrs; age at the illness onset = 2...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12348

    authors: Maric NP,Andric S,Mihaljevic M,Mirjanic T

    更新日期:2018-02-01 00:00:00

  • Applying economic models to estimate local economic benefits of improved coverage of early intervention for psychosis.

    abstract:AIM:Early Intervention Psychosis Services (EIPS) for people experiencing First Episode Psychosis (FEP) offer important clinical and non-clinical benefits over standard care. Similarly, intervention for Clinical High Risk for Psychosis state (CHR-P) can prevent psychosis, ameliorate symptoms and have non-clinical benefi...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12787

    authors: Campion J,Taylor MJ,McDaid D,Park AL,Shiers D

    更新日期:2019-12-01 00:00:00

  • Adolescent attention deficit hyperactivity disorder and susceptibility to psychosis in adulthood: a review of the literature and a phenomenological case report.

    abstract:AIM:In contrast to affective disorders, some forms of personality disorders and drug addiction, schizophrenia is commonly not considered to be a sequela of attention deficit hyperactivity disorder. However, attention deficit hyperactivity disorder and the prodromal stages of schizophrenia spectrum disorders do exhibit ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1111/j.1751-7893.2011.00293.x

    authors: Jandl M,Steyer J,Kaschka WP

    更新日期:2012-02-01 00:00:00

  • Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong.

    abstract:AIM:The current study explored the effect of an early intervention (EI) service for psychosis in Hong Kong (EASY) on the reduction of the duration of untreated psychosis (DUP) at 10 years, in adolescent and adult patients. METHOD:Data from three first-episode psychosis (FEP) studies conducted over 10 years using the s...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12313

    authors: Chan SKW,Chau EHS,Hui CLM,Chang WC,Lee EHM,Chen EYH

    更新日期:2018-06-01 00:00:00

  • Pre-pulse inhibition deficits in individuals at clinical high-risk for psychosis: A systematic review and meta-analysis.

    abstract:AIM:Neurophysiological markers of schizophrenia may help identify individuals who are at an increased risk of developing psychosis. As an operational measure of sensorimotor gating, pre-pulse inhibition (PPI) deficit has been investigated in clinical high-risk (CHR) individuals. In this study, we performed a systematic...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.13015

    authors: Li W,Mao Z,Bo Q,Sun Y,Wang Z,Wang C

    更新日期:2020-07-24 00:00:00

  • Perceptions of attenuated psychosis in a diverse sample of undergraduates.

    abstract:AIM:Prior to the release of the fifth edition of the Diagnostic and Statistical Manual for Mental Disorders, experts in the field of psychosis research considered including a psychosis high-risk syndrome-attenuated psychosis syndrome-as a formal diagnosis. Opponents argued that such a diagnosis may increase the risk of...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12710

    authors: Trask CL,Kameoka VA,Schiffman J,Cicero DC

    更新日期:2019-08-01 00:00:00

  • A comparison of early psychosis treatment services using consensus and evidence-based performance measures: moving towards setting standards.

    abstract:OBJECTIVE:This study used data from two Canadian early psychosis programs to assess the feasibility of using common performance measures and to assess the extent to which each program meets suggested standards for early intervention. METHODS:Data were extracted from administrative databases and supplemented by health ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2009.00143.x

    authors: Addington D,Norman R,Adair CE,Manchanda R,McKenzie E,Mitchell B,Pryce C

    更新日期:2009-11-01 00:00:00

  • Implementation case study: Multifamily group intervention in first-episode psychosis programs.

    abstract:AIM:Family interventions are a core component of first-episode psychosis (FEP) treatment; however, low implementation rates are consistently reported. As such, work is needed to understand the factors impacting real-world treatment delivery. The present paper describes the implementation of the McFarlane-model multifam...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.13066

    authors: Browne J,Sanders AS,Friedman-Yakoobian M,Guyer M,Keshavan M,Kim B,Kline E

    更新日期:2020-11-08 00:00:00

  • Distress and negative experiences of the caregiving relationship in early psychosis: does social cognition play a role?

    abstract:AIM:This study explored the relationship between individuals with early psychosis and first-degree relatives who were carers, to see whether negative and distressing experiences of the patient-carer relationship were associated with social cognition difficulties in both groups. METHOD:The study had a cross-sectional c...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12040

    authors: Tomlinson E,Onwumere J,Kuipers E

    更新日期:2014-08-01 00:00:00