Initial medical work-up of first-episode psychosis: a conceptual review.

Abstract:

AIM:To help clinicians carry out a comprehensive, medical diagnostic assessment in first-episode patients who are suspected of developing schizophrenia. METHODS:Conceptual review of the published work with emphasis on the diagnostic goals of excluding medical causes of psychosis and establishing a medical baseline. RESULTS:There is no agreed-upon standard for the initial medical work-up of first-episode cases. Excluding secondary causes of schizophrenia requires consideration of likelihood of disease; laboratory test performance; and relevance of positive test results. CONCLUSIONS:We propose a medical work-up for first-episode psychosis that combines: (i) broad screening; (ii) exclusion of specific diseases informed by treatability and epidemiology; and (iii) medical baseline measures.

authors

Freudenreich O,Schulz SC,Goff DC

doi

10.1111/j.1751-7893.2008.00105.x

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

10-8

issue

1

eissn

1751-7885

issn

1751-7893

journal_volume

3

pub_type

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