Abstract:
AIM:Early intervention programmes for first episode psychosis (FEP) aim to reduce the duration of untreated psychosis (DUP) and improve functional outcomes. The sustained maintenance of improved outcomes depends largely on patients' adherence to prescribed treatment. This paper examines the prevalence of non-adherence in a cohort of patients with FEP and the sociodemographic and clinical factors associated with non-adherent behaviour. METHODS:The sample included consecutive patients accepted from 2007 to 2012 into the Early Psychosis Intervention Programme (EPIP) in Singapore. Sociodemographic variables as well as DUP, insight, severity of psychopathology and clinical diagnoses were collected. Patients were assessed at baseline and 1 year with the PANSS and Global Assessment of Functioning Scale (GAF). Medication adherence was grouped into 3 categories: no-adherence, partial adherence and regular adherence. RESULTS:Of the 445 patients included, 51% were male with a mean age of 26.3 years, 74.6% had schizophrenia spectrum and delusional disorders, 14% had affective psychosis and 11.3% had brief psychotic disorder or psychotic disorder not otherwise specified. At 1 year follow up, 65.5% reported regular adherence, 18.7% were partially adherent and 15.8% were non-adherent. Non-adherence was correlated with male gender, living alone and having poorer judgement and insight. Partial adherence was associated with Malay ethnicity and having undergone national service. CONCLUSION:Medication adherence is prevalent in FEP and associated with a variety of factors. This study supports the use of culturally appropriate interventions in addressing barriers to adherence. Further studies would need to be done to address specific factors affecting adherence outcomes.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Tan C,Abdin E,Liang W,Poon LY,Poon NY,Verma Sdoi
10.1111/eip.12559subject
Has Abstractpub_date
2019-08-01 00:00:00pages
780-788issue
4eissn
1751-7885issn
1751-7893journal_volume
13pub_type
杂志文章abstract:AIMS:The aims of this study were 3-fold. We wished to investigate whether at baseline entry to an ultra-high risk (UHR) clinic whether: (1) perceptual abnormalities are more prevalent in those young people with co-morbid psychiatric diagnoses, (2) perceptual abnormalities are more prevalent in those young people with h...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12469
更新日期:2019-04-01 00:00:00
abstract:AIM:Cognitive deficit in psychotic illness is intensively studied, different cognitive subtypes have been suggested. In recent years, there has been an increase in the number of studies in patients with schizophrenia and their relatives searching for endophenotypes of the disease. The aim of our study was to investigat...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12982
更新日期:2020-06-02 00:00:00
abstract:AIMS:To explore the impact of a targeted case identification intervention, with training and education regarding first-episode psychosis and clinical high-risk syndromes, on the referral and identification of those at high risk. METHODS:Using a historical control design, referral information from pre-intervention and ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12750
更新日期:2019-08-01 00:00:00
abstract:AIM:Autism spectrum disorder (ASD) is a neurodevelopmental disorder impairing social skills and communication. Adolescents with ASD have sexual needs, but may not understand their physical and emotional development resulting in inappropriate sexual behaviour. The aim of this review is to describe the type of inappropri...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/eip.12265
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:This study explored phenomenological aspects of auditory verbal hallucinations (AVH) and other psychotic symptoms among youth with borderline personality disorder (BPD). METHODS:Sixty-eight outpatients, aged 15 to 25 years, were categorized into three groups according to their primary Diagnostic and Statisti...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12763
更新日期:2019-10-01 00:00:00
abstract:AIM:Individuals with a diagnosis of schizophrenia have a reduced life expectancy compared with the general population and cardiovascular disease is the major contributor to this early mortality. The use of second-generation antipsychotic (SGA) medications is associated with significant weight gain and metabolic side ef...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12083
更新日期:2014-08-01 00:00:00
abstract:AIM:Over the past 20 years, early management of psychosis has become both a research and policy priority. In Western countries, psychotic disorders appear more prevalent in migrant and minority ethnic groups than in native or dominant groups. Moreover, disparities exist in health conditions and access to care among imm...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12671
更新日期:2018-10-01 00:00:00
abstract:AIM:Thought disorder is a core feature of schizophrenia but assessment of disordered thinking is challenging, which may contribute to the paucity of mechanistic understanding of disorganization in early psychosis. We studied the use of linguistic connectives in relation to clinically quantified dimensions of thought di...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12948
更新日期:2020-03-03 00:00:00
abstract:AIM:Schizophrenia is a highly stigmatized disorder. Identification of youth at high risk for psychosis has the potential for improved outcomes. However, identifying youth at risk could subject them to increased public stigma. Using an experimental vignette design, this study examined relative levels of public stigma el...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12691
更新日期:2019-08-01 00:00:00
abstract:AIM:The goal of this paper is to provide clarification with regard to the nature of mediator and moderator variables and the statistical methods used to test for the existence of these variables. Particular attention will be devoted to discussing the ways in which the identification of mediator and moderator variables ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/j.1751-7893.2010.00177.x
更新日期:2010-05-01 00:00:00
abstract:AIM:Prior to the release of the fifth edition of the Diagnostic and Statistical Manual for Mental Disorders, experts in the field of psychosis research considered including a psychosis high-risk syndrome-attenuated psychosis syndrome-as a formal diagnosis. Opponents argued that such a diagnosis may increase the risk of...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12710
更新日期:2019-08-01 00:00:00
abstract:AIM:A modular symptom-specific (MSS) programme of early intervention group cognitive behaviour therapy for psychosis might confer additional therapeutic benefits and clinical and financial efficiency, but the approach is empirically untested. Therefore, we devised a novel MSS programme to test - in a culturally diverse...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12025
更新日期:2013-05-01 00:00:00
abstract:AIMS:Individual Placement and Support is the most defined and evidence-based approach to supported employment for severe mental illness, including recent-onset psychosis. However, there is limited evidence or detailed guidelines informing the management of mental illness disclosure to educators or employers when delive...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12030
更新日期:2013-08-01 00:00:00
abstract:AIM:Most studies on the determinants of psychosocial functioning in first-episode psychosis used few predictors. This study examines the effects of multiple cognitive domains and multiple symptoms on psychosocial functioning. METHODS:A total of 162 patients with a first-episode psychosis were assessed within 3 months ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12210
更新日期:2017-02-01 00:00:00
abstract:AIM:Although advances in the treatment of schizophrenia have been made, little is known about the process of recovery from first episode of schizophrenia (FES). To date, the study of recovery in the field of mental health has focused on long-term mental illness. This qualitative study addresses ways in which individual...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2010.00187.x
更新日期:2010-08-01 00:00:00
abstract:AIM:To design and assess the psychometric properties of a questionnaire to identify and measure factors that influence the identification of individuals at ultra-high risk for psychosis in primary care. It will inform the subsequent design of educational interventions to help general practitioners (GPs; primary care ph...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00296.x
更新日期:2012-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13036
更新日期:2020-09-04 00:00:00
abstract:AIM:This study investigated the behavioural correlates of caregiver attitudes among parents of youth at risk for psychosis and with recent-onset psychotic symptoms. METHODS:Forty adolescents identified as ultra-high-risk (UHR) for psychosis using the Structured Interview for Prodromal Syndromes, and their primary care...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2008.00088.x
更新日期:2008-11-01 00:00:00
abstract:AIM:Adolescents with psychotic disorders show deficits in IQ, attention, learning and memory, executive functioning, and processing speed that are related to important clinical variables including negative symptoms, adaptive functioning and academics. Previous studies have reported relatively consistent deficits with v...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2008.00075.x
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Both the nature and number of a wide range of prodromal symptoms have been related to the severity and type of psychopathology in the psychotic phase. However, at present there is an incomplete picture focused mainly on the positive pre-psychotic dimension. AIM:To characterize the prodromal phase retrospect...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12498
更新日期:2019-06-01 00:00:00
abstract:AIM:Self-determination theory (SDT) has demonstrated that human well-being is associated with the satisfaction of three basic psychological needs (ie, autonomy, competence and relatedness)-with more recent research highlighting the applicability of SDT to individuals with first-episode psychosis (FEP). These findings s...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12784
更新日期:2019-12-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13072
更新日期:2020-11-25 00:00:00
abstract:AIM:Family interventions are a core component of first-episode psychosis (FEP) treatment; however, low implementation rates are consistently reported. As such, work is needed to understand the factors impacting real-world treatment delivery. The present paper describes the implementation of the McFarlane-model multifam...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13066
更新日期:2020-11-08 00:00:00
abstract:AIM:To describe how a new partnership model of early intervention in psychosis, early intervention in psychosis (EIP) programme delivery in Canada attracted the interest of the community and acquired government funding. METHODS:The process by which a few individuals used a conceptual framework of integrated, collabora...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2009.00130.x
更新日期:2009-08-01 00:00:00
abstract::Young people attempting to access mental health services in the United Kingdom often find traditional models of care outdated, rigid, inaccessible and unappealing. Policy recommendations, research and service user opinion suggest that reform is needed to reflect the changing needs of young people. There is significant...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12452
更新日期:2018-08-01 00:00:00
abstract:AIM:Olfactory identification deficits (OIDs) are seen in schizophrenia patients and individuals at increased risk for psychosis but its pathophysiology remains unclear. Although dopaminergic imbalance is known to lie at the core of schizophrenia symptomatology, its role in the development of OIDs has not been elucidate...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12183
更新日期:2016-10-01 00:00:00
abstract:AIM:There is increasing concern regarding the use of cannabis among adolescents, especially given recent evidence highlighting its link with later mental disorders. Encouraging young people with mental health or drug issues to seek professional help is an important early intervention strategy; however, adolescents are ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2010.00252.x
更新日期:2011-02-01 00:00:00
abstract::The aim of this pilot study was to evaluate the utilisation and experience of an exercise physiology programme, known as Bod Squad at a youth mental health service. Individual sessions were offered in an outpatient setting, while both group and individual sessions occurred in an inpatient unit. This pilot study used a...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12436
更新日期:2018-08-01 00:00:00
abstract:AIM:Looking after someone in the early stages of psychosis can have a negative impact on caregivers, but there is little clarity about which interventions, if any, caregivers should be offered. This study investigated sleep disturbances in early psychosis caregivers and the relationship between their sleep quality and ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12538
更新日期:2019-06-01 00:00:00
abstract:AIMS:This study aimed to develop a comprehensive measurement tool for assessing client satisfaction at a youth mental health service. METHODS:We developed a scale based on existing scale items and by generating new items, before undertaking revisions and item reduction in consultation with an expert panel composed of ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12104
更新日期:2014-11-01 00:00:00