Abstract:
AIM:Adolescents with psychotic disorders show deficits in IQ, attention, learning and memory, executive functioning, and processing speed that are related to important clinical variables including negative symptoms, adaptive functioning and academics. Previous studies have reported relatively consistent deficits with varying relationships to illness status and symptoms. The goals of this study were to examine these relationships in a larger sample at baseline, and also to examine the longitudinal course of these deficits in a smaller subset of adolescents. METHOD:Thirty-six subjects, aged 10 to 17 years, were included at baseline. All had Diagnostic and Statistical Manual-Fourth Edition diagnoses of schizophrenia, schizoaffective disorder, schizophreniform disorder and psychosis - not otherwise specified, as determined by Kiddie-Schedule for Affective Disorders and Schizophrenia for School-Age Children structured interviews. Patients were administered a neuropsychological battery, and Positive and Negative Syndrome Scale ratings were completed at baseline and again at 1 year (n = 14). Most participants were inpatients at baseline, and 13 of 14 were on atypical antipsychotic medication during both sessions. RESULTS:At baseline, the patients demonstrated impairments in working memory, processing speed, executive function and verbal learning. No significant cognitive change was detected at 1-year follow-up. In contrast, clinical symptoms were variable across 1 year, with an improvement in positive symptoms at 1 year. No relationships between clinical and cognitive symptoms were observed, with the exception of baseline IQ predicting negative symptoms at 1 year. CONCLUSIONS:Young patients with schizophrenia-spectrum disorders displayed neurocognitive impairments at baseline. Despite measurable fluctuations in clinical symptoms over the year, no significant changes were measured in cognition. Lower IQ at baseline was predictive of more negative symptoms at 1 year.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Wozniak JR,Block EE,White T,Jensen JB,Schulz SCdoi
10.1111/j.1751-7893.2008.00075.xsubject
Has Abstractpub_date
2008-08-01 00:00:00pages
169-77issue
3eissn
1751-7885issn
1751-7893journal_volume
2pub_type
杂志文章abstract:AIM:Self-determination theory (SDT) has demonstrated that human well-being is associated with the satisfaction of three basic psychological needs (ie, autonomy, competence and relatedness)-with more recent research highlighting the applicability of SDT to individuals with first-episode psychosis (FEP). These findings s...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12784
更新日期:2019-12-01 00:00:00
abstract:AIMS:This report discusses the use of antinuclear antibody (ANA) detection as a screening test for neuropsychiatry systemic lupus erythematosus (NPSLE) in patients presenting a first-episode psychosis. METHODS:We reviewed the medical records of 85 patients admitted to an emergency service due to first-episode psychosi...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00339.x
更新日期:2012-08-01 00:00:00
abstract:AIM:New psychoactive substance (NPS) use can negatively impact mental health and may result in drug-related psychiatric admissions (DRPA). Irish youth reported very high rates of NPS use by international standards, the most common being synthetic cannabinoids and cathinones. This occurred in the context of a rapid expa...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12807
更新日期:2020-02-01 00:00:00
abstract:AIM:Fidelity monitoring can support high-quality service delivery but is resource-intensive to implement. A fidelity assessment model utilizing volunteer assessors was trialled as a low-cost strategy for conducting fidelity assessments. This article reports on the acceptability and feasibility of this model. METHODS:T...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12961
更新日期:2020-03-31 00:00:00
abstract:AIM:The Meals, Mindfulness, & Moving Forward (M3 ) programme included nutrition education, hands-on cooking classes, mindfulness meditation practice, physical activities and facilitated group sharing. M3 was designed as a supplement to standard care for youths (age 15-25 years) with first-episode psychosis (FEP) who we...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12913
更新日期:2021-02-01 00:00:00
abstract:AIM:Cognitive and functioning impairments are present early in the course of psychotic disorder and remain one of the greatest treatment challenges. Cognitive adaptation training (CAT) is a compensatory approach to psychosocial intervention that is underpinned by a model that incorporates the role of cognition in daily...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12207
更新日期:2016-12-01 00:00:00
abstract:AIM:In this study, we investigate the feasibility and acceptability of a 9-month psychoeducational multi-family group (PMFG) intervention for adolescents who are at ultra-high-risk (UHR) for developing psychosis. METHODS:The treatment programme was adapted from those previously shown to be effective in patients with e...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2007.00046.x
更新日期:2007-11-01 00:00:00
abstract:AIM:This study aims to evaluate the outcomes and economic case for a UK innovative youth-specific mental health service for 16-25 year olds. METHODS:A pre-, during- and post-treatment comparative design for 20 young people at high risk of developing psychosis who received 2 years' treatment with the service, using out...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12261
更新日期:2017-10-01 00:00:00
abstract:AIM:Neurophysiological markers of schizophrenia may help identify individuals who are at an increased risk of developing psychosis. As an operational measure of sensorimotor gating, pre-pulse inhibition (PPI) deficit has been investigated in clinical high-risk (CHR) individuals. In this study, we performed a systematic...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13015
更新日期:2020-07-24 00:00:00
abstract:AIM:Individuals with a diagnosis of schizophrenia have a reduced life expectancy compared with the general population and cardiovascular disease is the major contributor to this early mortality. The use of second-generation antipsychotic (SGA) medications is associated with significant weight gain and metabolic side ef...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12083
更新日期:2014-08-01 00:00:00
abstract:AIM:To explore the differences in pharmacotherapy and clinical characteristics of individuals at ultra-high-risk (UHR) for psychosis according to the conversion status, we analyzed the data for UHR patients seen at the Seoul Youth Clinic. METHODS:This was a naturalistic observational study. We obtained clinical data, ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00295.x
更新日期:2012-02-01 00:00:00
abstract::Young people use social media to communicate about suicide, however, they often feel ill-equipped to share their own experiences or to respond to expressions of risk by others. AIMS:To describe the adaptation of the Australian #chatsafe guidelines for an international audience, and their initial roll out via social m...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13044
更新日期:2020-09-15 00:00:00
abstract:OBJECTIVE:The onset of psychosis typically occurs during adolescence or early adulthood and can have a detrimental impact on social and cognitive development. Cognitive behavioural therapy (CBT) shows promise in reducing the risk of psychosis. Teaching families to apply CBT with their offspring may bolster therapeutic ...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12204
更新日期:2016-12-01 00:00:00
abstract:AIM:Previous research has demonstrated a strong association between early trauma exposure and the development of psychotic symptoms. However, few of these studies have included young adolescents and children. This study investigated rates and number of potentially traumatic experiences (PTEs) among typically developing...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12565
更新日期:2019-08-01 00:00:00
abstract:AIM:It has been found that long-chain omega-3 polyunsaturated fatty acids (PUFAs) reduce the risk of progression to first episode of psychosis (FEP) and may offer a safe and efficacious strategy for selective and indicated prevention in young people with ultra-high-risk (UHR) states. An opportunity for exploring the tr...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1111/eip.12197
更新日期:2016-10-01 00:00:00
abstract:AIMS:Individual Placement and Support is the most defined and evidence-based approach to supported employment for severe mental illness, including recent-onset psychosis. However, there is limited evidence or detailed guidelines informing the management of mental illness disclosure to educators or employers when delive...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12030
更新日期:2013-08-01 00:00:00
abstract:AIM:To increase our understanding of substance use among adolescents with psychosis by comparing their reasons for use with those of typically developing adolescents. METHODS:Participants were 35 outpatient adolescents, recently admitted for a first episode of psychosis to an early psychosis programme, and 35 typicall...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2007.00055.x
更新日期:2008-02-01 00:00:00
abstract:AIM:The duration of untreated psychosis (DUP) refers to the period of time between the emergence of psychotic symptoms and the initiation of appropriate clinical treatment. Prolonged DUP is associated with a range of adverse consequences, including more severe illness course, cognitive deficits and poor functioning. Pr...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12308
更新日期:2017-06-01 00:00:00
abstract:AIM:This study investigated the behavioural correlates of caregiver attitudes among parents of youth at risk for psychosis and with recent-onset psychotic symptoms. METHODS:Forty adolescents identified as ultra-high-risk (UHR) for psychosis using the Structured Interview for Prodromal Syndromes, and their primary care...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2008.00088.x
更新日期:2008-11-01 00:00:00
abstract:AIM:Transition to university is associated with unique stressors and coincides with the peak period of risk for onset of mental illness. Our objective in this analysis was to estimate the mental health need of students at entry to a major Canadian university. METHODS:After a student-led engagement campaign, all first ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12939
更新日期:2020-02-11 00:00:00
abstract:AIM:Ultrahigh risk (UHR) criteria, consisting of brief limited intermittent psychotic symptoms (BLIPS), attenuated psychotic symptoms (APS) and genetic risk and deterioration (GRD) syndrome are the most widely used criteria for assessing the clinical high-risk state for psychosis (CHR-P). The Basel Screening Instrument...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12719
更新日期:2019-08-01 00:00:00
abstract:AIM:To help clinicians carry out a comprehensive, medical diagnostic assessment in first-episode patients who are suspected of developing schizophrenia. METHODS:Conceptual review of the published work with emphasis on the diagnostic goals of excluding medical causes of psychosis and establishing a medical baseline. R...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/j.1751-7893.2008.00105.x
更新日期:2009-02-01 00:00:00
abstract:AIM:Individual Placement and Support is an effective vocational intervention for increasing competitive employment for people with severe mental illness. Little is known, however, about its effectiveness in the context of early psychosis. This study assesses improvements in clients' employment in a phase of illness dur...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13005
更新日期:2020-06-24 00:00:00
abstract:BACKGROUND:This article describes the development of the smartphone application for cognitive-behavioural case management of young individuals with early psychosis and examines the acceptance and potential clinical benefits of this application through a pilot survey. METHODS:Gwangju Bukgu-Community Mental Health Cente...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12418
更新日期:2018-12-01 00:00:00
abstract:AIM:As a foundation for considering how gains may be maintained following early intervention in first-episode psychosis (FEP), this study aimed to describe and investigate factors predicting post-discharge relapse and longer term functioning. METHOD:An evaluation via case-note review obtained quantitative data on 163 ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12099
更新日期:2015-08-01 00:00:00
abstract:AIM:Despite the potential benefits of e-health interventions for patients with psychosis, the integration of these applications into the clinical workflow and analysis of their long-term effects still face significant challenges. To address these issues, we developed the ReMindCare app. This app aims to improve the tre...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12960
更新日期:2021-02-01 00:00:00
abstract:AIM:To examine whether roles of peer specialists affect service use among Black, Latinx and White youth ages 16-24 with serious mental illness (SMI) in Los Angeles and San Diego Counties. METHODS:Administrative data from 2015 to 2018 was used to summarize service use among 6329 transition age youth age 16-24 with SMI ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13036
更新日期:2020-09-04 00:00:00
abstract:AIM:Attenuated psychotic symptoms (APSs) have been the primary emphasis in youth at clinical high risk (CHR) for psychosis for assessing symptomology and determining subsequent transition to a psychotic disorder. Previous reviews primarily focused on the efficacy of cognitive behavioural therapy (CBT) on APS; however, ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,meta分析
doi:10.1111/eip.12677
更新日期:2019-02-01 00:00:00
abstract:AIM:Early intervention programmes for first episode psychosis (FEP) aim to reduce the duration of untreated psychosis (DUP) and improve functional outcomes. The sustained maintenance of improved outcomes depends largely on patients' adherence to prescribed treatment. This paper examines the prevalence of non-adherence ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12559
更新日期:2019-08-01 00:00:00
abstract:AIM:The current study explored the effect of an early intervention (EI) service for psychosis in Hong Kong (EASY) on the reduction of the duration of untreated psychosis (DUP) at 10 years, in adolescent and adult patients. METHOD:Data from three first-episode psychosis (FEP) studies conducted over 10 years using the s...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12313
更新日期:2018-06-01 00:00:00