Abstract:
AIM:Cognitive deficit in psychotic illness is intensively studied, different cognitive subtypes have been suggested. In recent years, there has been an increase in the number of studies in patients with schizophrenia and their relatives searching for endophenotypes of the disease. The aim of our study was to investigate cognitive performance and cognitive subtypes in the siblings of the patients. METHODS:Four groups of subjects were included: patients with a first episode of psychotic illness, the siblings of these patients, and two control groups. All the study subjects (N = 84) had a battery of neuropsychological tests that measured basic cognitive domains - memory, executive functions, attention, visual-spatial skills, language skills and psychomotor speed - administered to them. The data were assessed with pairwise t-tests for group comparisons. The siblings were distributed into three groups according to their cognitive performance: non-deficit, partial deficit, and global deficit. Subsequently, the patients were assigned into three groups corresponding to their siblings' performance. RESULTS:Our results revealed attenuation of abstract thinking in the siblings compared to the controls. As expected, the patients showed impairment across all cognitive domains. The patients and siblings demonstrated similar profiles in each subtype, in the severity of their impairment, and in their patterns of cognitive performance. CONCLUSIONS:Our results suggest that the cognitive profile can be considered as an endophenotype of psychotic disorders.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Voráčková V,Knytl P,Španiel F,Šustová P,Renka J,Mohr Pdoi
10.1111/eip.12982subject
Has Abstractpub_date
2020-06-02 00:00:00eissn
1751-7885issn
1751-7893pub_type
杂志文章abstract:AIM:Individual placement and support (IPS) has a considerable body of evidence for its effectiveness in helping people with mental disorder to achieve and maintain competitive jobs. However, little data in young adult populations are currently available, especially in Europe. Aim of this study was to assess the effect ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12883
更新日期:2020-10-01 00:00:00
abstract:AIM:Prior to the release of the fifth edition of the Diagnostic and Statistical Manual for Mental Disorders, experts in the field of psychosis research considered including a psychosis high-risk syndrome-attenuated psychosis syndrome-as a formal diagnosis. Opponents argued that such a diagnosis may increase the risk of...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12710
更新日期:2019-08-01 00:00:00
abstract::The Early Psychosis Prevention and Intervention Centre Statewide Services (ESW) team provides training for multidisciplinary clinicians that specialise in early psychosis across the State of Victoria, Australia. The aim of this paper is to describe the 4-phase approach utilised by ESW to prepare for and deliver worksh...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12424
更新日期:2018-06-01 00:00:00
abstract:AIM:Reduced social network (SN) might be associated with a longer duration of untreated psychosis (DUP) in people with first episode psychosis (FEP). We aimed at exploring the specific role of SN confidants on DUP, taking into account cannabis misuse, which is known to influence DUP and might be associated with social ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12476
更新日期:2018-10-01 00:00:00
abstract:AIMS:The aims of this study were 3-fold. We wished to investigate whether at baseline entry to an ultra-high risk (UHR) clinic whether: (1) perceptual abnormalities are more prevalent in those young people with co-morbid psychiatric diagnoses, (2) perceptual abnormalities are more prevalent in those young people with h...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12469
更新日期:2019-04-01 00:00:00
abstract:AIM:Psychiatric comorbidity frequently occurs with at-risk mental state (ARMS) for psychosis. Its relationships with psychopathology, cognition and functioning, however, remain to be further clarified. We aimed to examine prevalence and correlates of psychiatric comorbidity, and its associations with psychosocial funct...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12992
更新日期:2020-05-22 00:00:00
abstract:AIM:Schizophrenia is a highly stigmatized disorder. Identification of youth at high risk for psychosis has the potential for improved outcomes. However, identifying youth at risk could subject them to increased public stigma. Using an experimental vignette design, this study examined relative levels of public stigma el...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12691
更新日期:2019-08-01 00:00:00
abstract:AIM:Self-determination theory (SDT) has demonstrated that human well-being is associated with the satisfaction of three basic psychological needs (ie, autonomy, competence and relatedness)-with more recent research highlighting the applicability of SDT to individuals with first-episode psychosis (FEP). These findings s...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12784
更新日期:2019-12-01 00:00:00
abstract:AIMS:To explore the impact of a targeted case identification intervention, with training and education regarding first-episode psychosis and clinical high-risk syndromes, on the referral and identification of those at high risk. METHODS:Using a historical control design, referral information from pre-intervention and ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12750
更新日期:2019-08-01 00:00:00
abstract:AIM:Computer-based virtual reality assessments of functional capacity have shown promise as a reliable and valid way to assess individuals with multi-episode schizophrenia. However, there has been little research utilizing this innovative approach with young patients who are in the early phase of schizophrenia. METHOD...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12831
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Approximately 80 000 children and young people in the UK suffer from depression, but many are untreated because of poor identification of early warning signs and risk factors. AIMS:This study aimed to derive and to investigate discrimination characteristics of a prediction model for a first recorded diagnos...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12332
更新日期:2018-06-01 00:00:00
abstract:AIM:This study explored the relationship between individuals with early psychosis and first-degree relatives who were carers, to see whether negative and distressing experiences of the patient-carer relationship were associated with social cognition difficulties in both groups. METHOD:The study had a cross-sectional c...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12040
更新日期:2014-08-01 00:00:00
abstract:AIM:To describe how a new partnership model of early intervention in psychosis, early intervention in psychosis (EIP) programme delivery in Canada attracted the interest of the community and acquired government funding. METHODS:The process by which a few individuals used a conceptual framework of integrated, collabora...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2009.00130.x
更新日期:2009-08-01 00:00:00
abstract:AIM:To design and assess the psychometric properties of a questionnaire to identify and measure factors that influence the identification of individuals at ultra-high risk for psychosis in primary care. It will inform the subsequent design of educational interventions to help general practitioners (GPs; primary care ph...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00296.x
更新日期:2012-08-01 00:00:00
abstract:AIM:This study aimed to examine the psychometric performance of the Recovering Quality of Life scale 10-item version (ReQoL-10) using a sample from a Singapore first-episode psychosis intervention program, to explore its clinical and sociodemographic correlates, and to discuss its utility as a patient-reported outcome ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13050
更新日期:2020-10-15 00:00:00
abstract:AIM:Early-onset schizophrenia (onset before adulthood) is a rare and severe form of the disorder that shows phenotypic and neurobiological continuity with adult-onset schizophrenia. Here, we provide a synthesis of keynote findings in this enriched population to understand better the neurobiology and pathophysiology of ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/j.1751-7893.2010.00253.x
更新日期:2011-02-01 00:00:00
abstract:AIM:The Meals, Mindfulness, & Moving Forward (M3 ) programme included nutrition education, hands-on cooking classes, mindfulness meditation practice, physical activities and facilitated group sharing. M3 was designed as a supplement to standard care for youths (age 15-25 years) with first-episode psychosis (FEP) who we...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12913
更新日期:2021-02-01 00:00:00
abstract:AIM:As a foundation for considering how gains may be maintained following early intervention in first-episode psychosis (FEP), this study aimed to describe and investigate factors predicting post-discharge relapse and longer term functioning. METHOD:An evaluation via case-note review obtained quantitative data on 163 ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12099
更新日期:2015-08-01 00:00:00
abstract:AIM:To examine whether roles of peer specialists affect service use among Black, Latinx and White youth ages 16-24 with serious mental illness (SMI) in Los Angeles and San Diego Counties. METHODS:Administrative data from 2015 to 2018 was used to summarize service use among 6329 transition age youth age 16-24 with SMI ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13036
更新日期:2020-09-04 00:00:00
abstract:AIM:This study investigated the behavioural correlates of caregiver attitudes among parents of youth at risk for psychosis and with recent-onset psychotic symptoms. METHODS:Forty adolescents identified as ultra-high-risk (UHR) for psychosis using the Structured Interview for Prodromal Syndromes, and their primary care...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2008.00088.x
更新日期:2008-11-01 00:00:00
abstract:AIM:New psychoactive substance (NPS) use can negatively impact mental health and may result in drug-related psychiatric admissions (DRPA). Irish youth reported very high rates of NPS use by international standards, the most common being synthetic cannabinoids and cathinones. This occurred in the context of a rapid expa...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12807
更新日期:2020-02-01 00:00:00
abstract:AIM:Depression and suicidal ideation (SUI) and behaviour are more prevalent in females than males, and common in clinical high-risk (CHR) patients. Childhood adversities and trauma (CAT) are associated with adult depression and SUI. The role of gender as a moderator and depression as a mediator for the effect of CAT on...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12714
更新日期:2019-08-01 00:00:00
abstract:AIM:Ultrahigh risk (UHR) criteria, consisting of brief limited intermittent psychotic symptoms (BLIPS), attenuated psychotic symptoms (APS) and genetic risk and deterioration (GRD) syndrome are the most widely used criteria for assessing the clinical high-risk state for psychosis (CHR-P). The Basel Screening Instrument...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12719
更新日期:2019-08-01 00:00:00
abstract:AIM:Autism spectrum disorder (ASD) is a neurodevelopmental disorder impairing social skills and communication. Adolescents with ASD have sexual needs, but may not understand their physical and emotional development resulting in inappropriate sexual behaviour. The aim of this review is to describe the type of inappropri...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/eip.12265
更新日期:2016-08-01 00:00:00
abstract:AIM:Conduct a systematic review for the effectiveness of school mental health literacy programs to enhance knowledge, reduce stigmatizing attitudes and improve help-seeking behaviours among youth (12-25 years of age). METHODS:Reviewers independently searched PubMed, PsycINFO, Cochrane Library, CINAHL, ERIC, grey liter...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/eip.12010
更新日期:2013-05-01 00:00:00
abstract:AIM:Social cognitive impairments are core features in 22q11.2 deletion syndrome (22q11.2DS) and schizophrenia (SCZ). Indeed, adults with 22q.11.2 DS often have poorer social competence as well as poorer performance on measures of social cognitive skills (emotion recognition and theory of mind, ToM) compared with typica...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12557
更新日期:2019-04-01 00:00:00
abstract:AIM:This study explores the mental health needs of teachers and how these might impact on their capacity to provide early identification and intervention strategies to support their student's emotional well-being. METHOD:The present study surveyed a sample of UK teachers (N = 320) to explore the impact of work-related...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12264
更新日期:2017-12-01 00:00:00
abstract:AIM:Looking after someone in the early stages of psychosis can have a negative impact on caregivers, but there is little clarity about which interventions, if any, caregivers should be offered. This study investigated sleep disturbances in early psychosis caregivers and the relationship between their sleep quality and ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12538
更新日期:2019-06-01 00:00:00
abstract:AIM:Valid instruments for the early identification of psychotic experiences (PE) and symptoms in youths are urgently needed for large-scale preventive interventions. A new section of The-Development-and-Well-Being Assessment (DAWBA) measuring child self-reported PE has yet to be validated. The current study aimed to in...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12547
更新日期:2019-06-01 00:00:00
abstract:AIM:People diagnosed with mental disorders experience higher rates of unemployment than those without. Career adaptability, defined as the ability to respond flexibly and make informed career decisions in work and throughout career transitions, is becoming increasingly important as the nature of work changes rapidly. E...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13100
更新日期:2021-01-10 00:00:00