Abstract:
AIM:In the clinical high-risk (CHR) state for psychosis, both negative symptoms and lower cognitive function have been associated with poorer daily functioning. Recent evidence suggests that negative symptoms share overlapping variability with cognition and may partially mediate the relationship between cognition and functioning. However, the nature of this overlap is unknown, and the reverse mediation model remains untested leaving the precise nature of these associations unclear. METHODS:In order to clarify these relationships, a sample of community-dwelling youth meeting CHR criteria was collected from a specialty CHR clinic (n = 91, mean age = 21, 63% male). Bootstrapping methods were then applied in a mediation analysis to test both negative symptoms and cognition as independent variables and mediating variables predicting social and role functioning in CHR individuals. Canonical correlation analysis was used to characterize the overlapping variability between negative symptoms and cognition. RESULTS:Support for a primary role of negative symptoms in predicting functioning and cognition was observed. Canonical correlation revealed a single dimension of overlap between the two symptom types (r = .62), represented by a strong correlation between negative symptoms in general and tasks involving verbal working memory, vigilance and social cognition specifically. A single cognitive factor composed primarily of these tasks was found to predict role functioning (adjusted R 2 = .04). CONCLUSIONS:The results highlight the importance of considering specific cognitive mechanisms overlapping with negative symptoms in research and rehabilitative practice in CHR populations, as well as the primary importance of targeting negative symptoms.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Gerritsen C,Maheandiran M,Lepock J,Ahmed S,Kiang M,Bagby RM,Mizrahi Rdoi
10.1111/eip.12843subject
Has Abstractpub_date
2020-04-01 00:00:00pages
188-195issue
2eissn
1751-7885issn
1751-7893journal_volume
14pub_type
杂志文章abstract:AIMS:To review intervention variables and outcomes of studies designed to increase physical activity or exercise participation among people experiencing first-episode psychosis. METHODS:A systematic review of electronic databases was conducted from inception to November 2014. RESULTS:Eleven eligible studies describin...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/eip.12238
更新日期:2016-10-01 00:00:00
abstract:AIM:In psychotic disorders, a limited number of studies have documented the presence of symptoms of anxiety, especially in first-episode psychosis (FEP). There is a growing interest in better understanding how these symptoms may affect the severity of psychotic symptoms and clinical outcome. This study examined the ass...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12018
更新日期:2013-02-01 00:00:00
abstract:AIMS:This study aimed to develop a comprehensive measurement tool for assessing client satisfaction at a youth mental health service. METHODS:We developed a scale based on existing scale items and by generating new items, before undertaking revisions and item reduction in consultation with an expert panel composed of ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12104
更新日期:2014-11-01 00:00:00
abstract:AIM:Individuals with a diagnosis of schizophrenia have a reduced life expectancy compared with the general population and cardiovascular disease is the major contributor to this early mortality. The use of second-generation antipsychotic (SGA) medications is associated with significant weight gain and metabolic side ef...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12083
更新日期:2014-08-01 00:00:00
abstract:AIM:Social cognitive impairments are core features in 22q11.2 deletion syndrome (22q11.2DS) and schizophrenia (SCZ). Indeed, adults with 22q.11.2 DS often have poorer social competence as well as poorer performance on measures of social cognitive skills (emotion recognition and theory of mind, ToM) compared with typica...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12557
更新日期:2019-04-01 00:00:00
abstract:AIM:Suicidal behaviours (suicide attempts and suicides) are common among individuals experiencing, or having recently experienced, a first-episode psychosis (FEP). Current interventions for suicidal behaviours are crisis driven and focused on hospital admission of patients at imminent risk of ending their lives. This p...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12084
更新日期:2014-11-01 00:00:00
abstract:AIM:Individual Placement and Support is an effective vocational intervention for increasing competitive employment for people with severe mental illness. Little is known, however, about its effectiveness in the context of early psychosis. This study assesses improvements in clients' employment in a phase of illness dur...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13005
更新日期:2020-06-24 00:00:00
abstract:AIM:The early intervention (EI) model appears to improve outcomes of psychosis for younger people, and there is now interest in implementing it in older groups. In the UK, the National Institute of Clinical Excellence advised that EI should be accessible to all individuals with first episode psychosis (FEP). We aimed t...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12322
更新日期:2018-06-01 00:00:00
abstract:AIM:The current study explored the effect of an early intervention (EI) service for psychosis in Hong Kong (EASY) on the reduction of the duration of untreated psychosis (DUP) at 10 years, in adolescent and adult patients. METHOD:Data from three first-episode psychosis (FEP) studies conducted over 10 years using the s...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12313
更新日期:2018-06-01 00:00:00
abstract:AIM:Olfactory identification deficits (OIDs) are seen in schizophrenia patients and individuals at increased risk for psychosis but its pathophysiology remains unclear. Although dopaminergic imbalance is known to lie at the core of schizophrenia symptomatology, its role in the development of OIDs has not been elucidate...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12183
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Approximately 80 000 children and young people in the UK suffer from depression, but many are untreated because of poor identification of early warning signs and risk factors. AIMS:This study aimed to derive and to investigate discrimination characteristics of a prediction model for a first recorded diagnos...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12332
更新日期:2018-06-01 00:00:00
abstract:AIM:To increase our understanding of substance use among adolescents with psychosis by comparing their reasons for use with those of typically developing adolescents. METHODS:Participants were 35 outpatient adolescents, recently admitted for a first episode of psychosis to an early psychosis programme, and 35 typicall...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2007.00055.x
更新日期:2008-02-01 00:00:00
abstract:AIM:Potential differences in psychiatric clinical outcomes and hospitalization rates before and after the initiation of long-acting risperidone among recently and long-term diagnosed schizophrenia patients were studied. METHODS:Data from two observational studies (Trial for the Initiation and Maintenance Of REmission ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12017
更新日期:2014-02-01 00:00:00
abstract:AIM:It is unclear how adult mindfulness-based interventions (MBIs) should be modified for youth, and at what ages programmes should be implemented for optimal impact. Recent non-replication with a 9-week programme in early adolescence suggested abbreviated programme content might be insufficient and/or that this age gr...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12801
更新日期:2019-12-01 00:00:00
abstract:AIM:Looking after someone in the early stages of psychosis can have a negative impact on caregivers, but there is little clarity about which interventions, if any, caregivers should be offered. This study investigated sleep disturbances in early psychosis caregivers and the relationship between their sleep quality and ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12538
更新日期:2019-06-01 00:00:00
abstract:AIM:Improvement of social adjustment is a major aim of indicated prevention in young people at risk of developing psychosis. The present study explores the effect of specific cognitive behaviour therapy (CBT) as compared with supportive counselling (SC) on social adjustment in people in a potential early initial prodro...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1751-7893.2007.00013.x
更新日期:2007-02-01 00:00:00
abstract:AIM:This paper considers the priorities for policy to promote youth mental health in Australia. The Ottawa Charter is applied as a conceptual framework to determine current strengths and future priorities across the entire spectrum of interventions for mental health promotion. METHODS:The five platforms of the Ottawa ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2010.00239.x
更新日期:2011-02-01 00:00:00
abstract:AIM:Early Intervention Psychosis Services (EIPS) for people experiencing First Episode Psychosis (FEP) offer important clinical and non-clinical benefits over standard care. Similarly, intervention for Clinical High Risk for Psychosis state (CHR-P) can prevent psychosis, ameliorate symptoms and have non-clinical benefi...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12787
更新日期:2019-12-01 00:00:00
abstract:AIM:This study aimed to explore the presence of psychotic like experience (PLE) symptoms and evaluate for the possible socio-demographic, family, school and mental health variables associated with clinically significant PLE symptoms in Nigeria school adolescent. METHODS:A total of 9441 adolescents from 47 secondary sc...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13032
更新日期:2020-09-02 00:00:00
abstract::The Early Psychosis Prevention and Intervention Centre Statewide Services (ESW) team provides training for multidisciplinary clinicians that specialise in early psychosis across the State of Victoria, Australia. The aim of this paper is to describe the 4-phase approach utilised by ESW to prepare for and deliver worksh...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12424
更新日期:2018-06-01 00:00:00
abstract:AIM:New psychoactive substance (NPS) use can negatively impact mental health and may result in drug-related psychiatric admissions (DRPA). Irish youth reported very high rates of NPS use by international standards, the most common being synthetic cannabinoids and cathinones. This occurred in the context of a rapid expa...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12807
更新日期:2020-02-01 00:00:00
abstract:AIMS:The aims of this study were 3-fold. We wished to investigate whether at baseline entry to an ultra-high risk (UHR) clinic whether: (1) perceptual abnormalities are more prevalent in those young people with co-morbid psychiatric diagnoses, (2) perceptual abnormalities are more prevalent in those young people with h...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12469
更新日期:2019-04-01 00:00:00
abstract:AIM:Valid instruments for the early identification of psychotic experiences (PE) and symptoms in youths are urgently needed for large-scale preventive interventions. A new section of The-Development-and-Well-Being Assessment (DAWBA) measuring child self-reported PE has yet to be validated. The current study aimed to in...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12547
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Both the nature and number of a wide range of prodromal symptoms have been related to the severity and type of psychopathology in the psychotic phase. However, at present there is an incomplete picture focused mainly on the positive pre-psychotic dimension. AIM:To characterize the prodromal phase retrospect...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12498
更新日期:2019-06-01 00:00:00
abstract:AIM:Auditory hallucinations are hypothesized to be based in distorted sensory perceptions, with increasingly distorted perceptions of reality possibly prompting the first psychotic phase of schizophrenia spectrum disorders. Our goal was to examine the association between distorted auditory perceptions and psychotic sym...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12150
更新日期:2015-06-01 00:00:00
abstract:AIM:Cognitive deficit in psychotic illness is intensively studied, different cognitive subtypes have been suggested. In recent years, there has been an increase in the number of studies in patients with schizophrenia and their relatives searching for endophenotypes of the disease. The aim of our study was to investigat...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12982
更新日期:2020-06-02 00:00:00
abstract:AIM:The Meals, Mindfulness, & Moving Forward (M3 ) programme included nutrition education, hands-on cooking classes, mindfulness meditation practice, physical activities and facilitated group sharing. M3 was designed as a supplement to standard care for youths (age 15-25 years) with first-episode psychosis (FEP) who we...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12913
更新日期:2021-02-01 00:00:00
abstract:AIM:Cognitive and functioning impairments are present early in the course of psychotic disorder and remain one of the greatest treatment challenges. Cognitive adaptation training (CAT) is a compensatory approach to psychosocial intervention that is underpinned by a model that incorporates the role of cognition in daily...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12207
更新日期:2016-12-01 00:00:00
abstract:AIM:Self-determination theory (SDT) has demonstrated that human well-being is associated with the satisfaction of three basic psychological needs (ie, autonomy, competence and relatedness)-with more recent research highlighting the applicability of SDT to individuals with first-episode psychosis (FEP). These findings s...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12784
更新日期:2019-12-01 00:00:00
abstract:AIM:Individual placement and support (IPS) has a considerable body of evidence for its effectiveness in helping people with mental disorder to achieve and maintain competitive jobs. However, little data in young adult populations are currently available, especially in Europe. Aim of this study was to assess the effect ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12883
更新日期:2020-10-01 00:00:00