Abstract:
AIM:Social cognitive impairments are core features in 22q11.2 deletion syndrome (22q11.2DS) and schizophrenia (SCZ). Indeed, adults with 22q.11.2 DS often have poorer social competence as well as poorer performance on measures of social cognitive skills (emotion recognition and theory of mind, ToM) compared with typically developing people. However, studies comparing specific social cognitive components in 22q11.2DS and SCZ have not yet been widely conducted. METHODS:In this study we compared performances of 22q11.2DS and SCZ on both facial emotion recognition and ToM. Patients with 22q11.2DS (n = 18) and matched SCZ patients were recruited. After neuropsychological testing, the facial emotion recognition test assessed the patients' ability to recognize six basic, universal emotions (joy, anger, sadness, fear, disgust, and contempt). The Versailles-situational intentional reading evaluated ToM with six scenes from movies showing characters in complex interactions (involving hints, lies, and indirect speech). RESULTS:We show that 22q11.2DS exhibited significantly lower performance in emotion recognition than SCZ patients did, especially for disgust, contempt, and fear. This impairment seems to be a core cognitive phenotype in 22q11.2DS, regardless of the presence of SCZ symptoms. Concerning ToM, our results may highlight the same impairment level in 22q11.2DS and SCZ but require to be replicated in a larger cohort. CONCLUSION:Our results document the existence of threshold social cognitive deficits distinguishing 22q11.2DS from SCZ.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Peyroux E,Rigard C,Saucourt G,Poisson A,Plasse J,Franck N,Demily Cdoi
10.1111/eip.12557subject
Has Abstractpub_date
2019-04-01 00:00:00pages
304-307issue
2eissn
1751-7885issn
1751-7893journal_volume
13pub_type
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章,meta分析
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2010.00252.x
更新日期:2011-02-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2009.00143.x
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12559
更新日期:2019-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00281.x
更新日期:2011-08-01 00:00:00
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journal_title:Early intervention in psychiatry
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更新日期:2020-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12116
更新日期:2015-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12714
更新日期:2019-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12843
更新日期:2020-04-01 00:00:00
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2020-12-09 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12164
更新日期:2016-06-01 00:00:00
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journal_title:Early intervention in psychiatry
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更新日期:2013-02-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2012.00387.x
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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