Abstract:
AIM:Within schizophrenia, genetic factors contribute greatly to risk, yet genetic testing for the disorder is not available. For some individuals with specific genotypes, cannabis use may increase risk of schizophrenia. It is possible that genetic tests could be offered in the future to inform individuals of the risk of schizophrenia if they use cannabis. Previous research, however, provides little guidance on how young adults might respond to such tests. METHODS:We assessed a group of young adults (n = 83) to determine how the perceived magnitude of increased risk for schizophrenia in the presence of cannabis use influences decisions to undergo genetic testing, as well as subsequent attitudes and intentions towards cannabis use. RESULTS:Participants were significantly more likely to indicate willingness to get tested if the results identified a 10% risk versus a 2% risk of schizophrenia. Participants also indicated that if the results of their test reflected increased risk due to cannabis use, it would be more important to avoid cannabis in the 10% risk scenario as compared to the 2% risk scenario. These findings remained consistent among a subset of participants who indicated cannabis use. CONCLUSIONS:Results suggest that cannabis users and non-users were positively influenced in terms of intentions to change behaviour based on the magnitude of risk conveyed by genetic testing. These findings provide an initial step towards understanding young people's attitudes towards genetic testing and may help prepare interventions specifically tailored around cannabis use reduction for people at risk for schizophrenia.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Schiffman J,Lawrence RE,Demro C,Appelbaum PS,Dixon LBdoi
10.1111/eip.12164subject
Has Abstractpub_date
2016-06-01 00:00:00pages
220-6issue
3eissn
1751-7885issn
1751-7893journal_volume
10pub_type
杂志文章abstract:AIM:This study aimed to explore the presence of psychotic like experience (PLE) symptoms and evaluate for the possible socio-demographic, family, school and mental health variables associated with clinically significant PLE symptoms in Nigeria school adolescent. METHODS:A total of 9441 adolescents from 47 secondary sc...
journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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更新日期:2020-08-01 00:00:00
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
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更新日期:2019-04-01 00:00:00
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
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更新日期:2016-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2010.00248.x
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journal_title:Early intervention in psychiatry
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更新日期:2020-11-25 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12714
更新日期:2019-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12538
更新日期:2019-06-01 00:00:00
abstract:AIM:Childhood adversities have been linked to an increased risk for psychosis. However, as yet, there has been comparatively little research on the effects of neglect. This study examined the association between childhood physical neglect and psychotic experiences (PEs) in a general population sample. METHODS:Data wer...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12932
更新日期:2020-02-11 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00281.x
更新日期:2011-08-01 00:00:00
abstract:AIM:To design and assess the psychometric properties of a questionnaire to identify and measure factors that influence the identification of individuals at ultra-high risk for psychosis in primary care. It will inform the subsequent design of educational interventions to help general practitioners (GPs; primary care ph...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2012-08-01 00:00:00
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2008.00065.x
更新日期:2008-05-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2013-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2018-10-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
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journal_title:Early intervention in psychiatry
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/eip.12501
更新日期:2018-08-01 00:00:00