Attitudes towards cannabis use and genetic testing for schizophrenia.

Abstract:

AIM:Within schizophrenia, genetic factors contribute greatly to risk, yet genetic testing for the disorder is not available. For some individuals with specific genotypes, cannabis use may increase risk of schizophrenia. It is possible that genetic tests could be offered in the future to inform individuals of the risk of schizophrenia if they use cannabis. Previous research, however, provides little guidance on how young adults might respond to such tests. METHODS:We assessed a group of young adults (n = 83) to determine how the perceived magnitude of increased risk for schizophrenia in the presence of cannabis use influences decisions to undergo genetic testing, as well as subsequent attitudes and intentions towards cannabis use. RESULTS:Participants were significantly more likely to indicate willingness to get tested if the results identified a 10% risk versus a 2% risk of schizophrenia. Participants also indicated that if the results of their test reflected increased risk due to cannabis use, it would be more important to avoid cannabis in the 10% risk scenario as compared to the 2% risk scenario. These findings remained consistent among a subset of participants who indicated cannabis use. CONCLUSIONS:Results suggest that cannabis users and non-users were positively influenced in terms of intentions to change behaviour based on the magnitude of risk conveyed by genetic testing. These findings provide an initial step towards understanding young people's attitudes towards genetic testing and may help prepare interventions specifically tailored around cannabis use reduction for people at risk for schizophrenia.

authors

Schiffman J,Lawrence RE,Demro C,Appelbaum PS,Dixon LB

doi

10.1111/eip.12164

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

220-6

issue

3

eissn

1751-7885

issn

1751-7893

journal_volume

10

pub_type

杂志文章
  • Psychotic like experiences among Nigerian school adolescents: Findings from the Lagos Schools Emotional and Behavioral Health Survey.

    abstract:AIM:This study aimed to explore the presence of psychotic like experience (PLE) symptoms and evaluate for the possible socio-demographic, family, school and mental health variables associated with clinically significant PLE symptoms in Nigeria school adolescent. METHODS:A total of 9441 adolescents from 47 secondary sc...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.13032

    authors: Adewuya AO,Wright K,Njokanma F

    更新日期:2020-09-02 00:00:00

  • Promoting youth mental health: priorities for policy from an Australian perspective.

    abstract:AIM:This paper considers the priorities for policy to promote youth mental health in Australia. The Ottawa Charter is applied as a conceptual framework to determine current strengths and future priorities across the entire spectrum of interventions for mental health promotion. METHODS:The five platforms of the Ottawa ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2010.00239.x

    authors: Rickwood DJ

    更新日期:2011-02-01 00:00:00

  • Youth at ultra high risk for psychosis: using the Revised Network Episode Model to examine pathways to mental health care.

    abstract:AIM:This paper aims to identify the ways in which youth at ultra high risk for psychosis access mental health services and the factors that advance or delay help seeking, using the Revised Network Episode Model (REV NEM) of mental health care. METHODS:A case study approach documents help-seeking pathways, encompassing...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2012.00350.x

    authors: Boydell KM,Volpe T,Gladstone BM,Stasiulis E,Addington J

    更新日期:2013-05-01 00:00:00

  • Concordance of child self-reported psychotic experiences with interview- and observer-based psychotic experiences.

    abstract:AIM:Valid instruments for the early identification of psychotic experiences (PE) and symptoms in youths are urgently needed for large-scale preventive interventions. A new section of The-Development-and-Well-Being Assessment (DAWBA) measuring child self-reported PE has yet to be validated. The current study aimed to in...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12547

    authors: Gundersen SV,Goodman R,Clemmensen L,Rimvall MK,Munkholm A,Rask CU,Skovgaard AM,Van Os J,Jeppesen P

    更新日期:2019-06-01 00:00:00

  • Feasibility and acceptability of cognitive adaptation training for first-episode psychosis.

    abstract:AIM:Cognitive and functioning impairments are present early in the course of psychotic disorder and remain one of the greatest treatment challenges. Cognitive adaptation training (CAT) is a compensatory approach to psychosocial intervention that is underpinned by a model that incorporates the role of cognition in daily...

    journal_title:Early intervention in psychiatry

    pub_type: 临床试验,杂志文章

    doi:10.1111/eip.12207

    authors: Allott KA,Killackey E,Sun P,Brewer WJ,Velligan DI

    更新日期:2016-12-01 00:00:00

  • Does an integrated outreach intervention targeting multiple stages of early psychosis improve the identification of individuals at clinical high risk?

    abstract:AIMS:To explore the impact of a targeted case identification intervention, with training and education regarding first-episode psychosis and clinical high-risk syndromes, on the referral and identification of those at high risk. METHODS:Using a historical control design, referral information from pre-intervention and ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12750

    authors: McIlwaine SV,Jordan G,Pruessner M,Malla A,Faridi K,Iyer SN,Joober R,Shah JL

    更新日期:2019-08-01 00:00:00

  • Suicidal behaviours during treatment for first-episode psychosis: towards a comprehensive approach to service-based prevention.

    abstract:AIM:Suicidal behaviours (suicide attempts and suicides) are common among individuals experiencing, or having recently experienced, a first-episode psychosis (FEP). Current interventions for suicidal behaviours are crisis driven and focused on hospital admission of patients at imminent risk of ending their lives. This p...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12084

    authors: Fedyszyn IE,Robinson J,Harris MG,Paxton SJ,Francey S,Edwards J

    更新日期:2014-11-01 00:00:00

  • Duration of untreated psychosis and acute remission of negative symptoms in a South American first-episode psychosis cohort.

    abstract:AIM:To determine the association between duration of untreated psychosis (DUP) and symptoms remission in a hospitalized first-episode psychosis cohort. METHODS:Inpatients with a first-episode non-affective psychosis were recruited. Subjects were divided into two groups of long and short DUP using a 3-month cut-off poi...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12266

    authors: González-Valderrama A,Castañeda CP,Mena C,Undurraga J,Mondaca P,Yañez M,Bedregal P,Nachar R

    更新日期:2017-02-01 00:00:00

  • A novel approach to improve stress regulation among traumatized youth in residential care: Feasibility study testing three game-based meditation interventions.

    abstract:AIM:Many youth in residential care suffer from post-traumatic symptoms that have adverse effects on a range of psychological, behavioural and physiological outcomes. Although current evidence-based treatment options are effective, they have their limitations. Meditation interventions are an alternative to traditional t...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12874

    authors: Schuurmans AAT,Nijhof KS,Scholte R,Popma A,Otten R

    更新日期:2020-08-01 00:00:00

  • Stigma and treatment delay in first-episode psychosis: a grounded theory study.

    abstract:AIM:A longer duration of untreated psychosis (DUP) is associated with greater morbidity in the early course of schizophrenia. This formative, hypothesis-generating study explored the effects of stigma, as perceived by family members, on DUP. METHODS:Qualitative interviews were conducted with 12 African American family...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2009.00155.x

    authors: Franz L,Carter T,Leiner AS,Bergner E,Thompson NJ,Compton MT

    更新日期:2010-02-01 00:00:00

  • Disagreement between service-users and clinicians assessment of physical health during early psychosis.

    abstract:AIMS:Physical illnesses account for the majority of excess deaths following psychosis; access to care and treatment is inequitable and schizophrenia has now been dubbed the life-shortening disease. We compared service-users and clinician's perspectives of their physical health assuming that one of the fundamental issue...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12668

    authors: Renwick L,Drennan J,Sheridan A,Lyne J,Kinsella A,O' Callaghan E,Clarke M

    更新日期:2019-04-01 00:00:00

  • The effectiveness of school mental health literacy programs to address knowledge, attitudes and help seeking among youth.

    abstract:AIM:Conduct a systematic review for the effectiveness of school mental health literacy programs to enhance knowledge, reduce stigmatizing attitudes and improve help-seeking behaviours among youth (12-25 years of age). METHODS:Reviewers independently searched PubMed, PsycINFO, Cochrane Library, CINAHL, ERIC, grey liter...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1111/eip.12010

    authors: Wei Y,Hayden JA,Kutcher S,Zygmunt A,McGrath P

    更新日期:2013-05-01 00:00:00

  • Inappropriate sexual behaviour in adolescents with autism spectrum disorder: what education is recommended and why.

    abstract:AIM:Autism spectrum disorder (ASD) is a neurodevelopmental disorder impairing social skills and communication. Adolescents with ASD have sexual needs, but may not understand their physical and emotional development resulting in inappropriate sexual behaviour. The aim of this review is to describe the type of inappropri...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1111/eip.12265

    authors: Beddows N,Brooks R

    更新日期:2016-08-01 00:00:00

  • Teachers' awareness for psychotic symptoms in secondary school: the effects of an early detection programme and information campaign.

    abstract:AIM:The objective of the study was to investigate high school teacher's literacy on psychosis symptoms and teachers' confidence in the positive effects of psychosis treatment on the mental health of students with psychotic symptoms at two sites: one site with an extensive early detection of psychosis programme includin...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2010.00248.x

    authors: Langeveld J,Joa I,Larsen TK,Rennan JA,Cosmovici E,Johannessen JO

    更新日期:2011-05-01 00:00:00

  • Mental health first aid by Australian tertiary staff: Application rates, modes, content, and outcomes.

    abstract:AIM:Mental health problems are a growing challenge in tertiary institutions warranting psycho-educational intervention programmes such as mental health first aid (MHFA) that provide training to identify and support affected individuals. The present study assesses the impact of MHFA interventions on tertiary students an...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.13072

    authors: Carpini JA,Chandra J,Lin J,Teo R,Truong N,Boyne E,Wylde T,Clifford R,Ashoorian D

    更新日期:2020-11-25 00:00:00

  • Childhood adversity predicts persistence of suicidal thoughts differently in females and males at clinical high-risk patients of psychosis. Results of the EPOS project.

    abstract:AIM:Depression and suicidal ideation (SUI) and behaviour are more prevalent in females than males, and common in clinical high-risk (CHR) patients. Childhood adversities and trauma (CAT) are associated with adult depression and SUI. The role of gender as a moderator and depression as a mediator for the effect of CAT on...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12714

    authors: Salokangas RKR,Patterson P,Hietala J,Heinimaa M,From T,Ilonen T,von Reventlow HG,Schultze-Lutter F,Juckel G,Linszen D,Dingemans P,Birchwood M,Klosterkötter J,Ruhrmann S,EPOS group.

    更新日期:2019-08-01 00:00:00

  • Role of poor sleep in determining distress in caregivers of individuals with early psychosis.

    abstract:AIM:Looking after someone in the early stages of psychosis can have a negative impact on caregivers, but there is little clarity about which interventions, if any, caregivers should be offered. This study investigated sleep disturbances in early psychosis caregivers and the relationship between their sleep quality and ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12538

    authors: Smith LM,Onwumere J,Craig T,Kuipers E

    更新日期:2019-06-01 00:00:00

  • Childhood physical neglect and psychotic experiences: Findings from the National Comorbidity Survey Replication.

    abstract:AIM:Childhood adversities have been linked to an increased risk for psychosis. However, as yet, there has been comparatively little research on the effects of neglect. This study examined the association between childhood physical neglect and psychotic experiences (PEs) in a general population sample. METHODS:Data wer...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12932

    authors: Stickley A,Waldman K,Sumiyoshi T,Narita Z,Shirama A,Shin JI,Oh H

    更新日期:2020-02-11 00:00:00

  • Themes of delusions and hallucinations in first-episode psychosis.

    abstract:AIM:The study aims to examine the themes of delusions and hallucinations in a cohort of adolescent and young adult patients (aged 15-26 years) presenting with a first episode of psychosis. METHODS:Information was collected retrospectively from 143 randomly selected medical files, using a questionnaire. RESULTS:Over 7...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2011.00281.x

    authors: Rajapakse T,Garcia-Rosales A,Weerawardene S,Cotton S,Fraser R

    更新日期:2011-08-01 00:00:00

  • Use of the theory of planned behaviour to assess factors influencing the identification of individuals at ultra-high risk for psychosis in primary care.

    abstract:AIM:To design and assess the psychometric properties of a questionnaire to identify and measure factors that influence the identification of individuals at ultra-high risk for psychosis in primary care. It will inform the subsequent design of educational interventions to help general practitioners (GPs; primary care ph...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2011.00296.x

    authors: Russo DA,Stochl J,Croudace TJ,Graffy JP,Youens J,Jones PB,Perez J

    更新日期:2012-08-01 00:00:00

  • Perceptual abnormalities in an ultra-high risk for psychosis population relationship to trauma and co-morbid disorder.

    abstract:AIMS:The aims of this study were 3-fold. We wished to investigate whether at baseline entry to an ultra-high risk (UHR) clinic whether: (1) perceptual abnormalities are more prevalent in those young people with co-morbid psychiatric diagnoses, (2) perceptual abnormalities are more prevalent in those young people with h...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12469

    authors: O' Connor K,Nelson B,Cannon M,Yung A,Thompson A

    更新日期:2019-04-01 00:00:00

  • Pre-pulse inhibition deficits in individuals at clinical high-risk for psychosis: A systematic review and meta-analysis.

    abstract:AIM:Neurophysiological markers of schizophrenia may help identify individuals who are at an increased risk of developing psychosis. As an operational measure of sensorimotor gating, pre-pulse inhibition (PPI) deficit has been investigated in clinical high-risk (CHR) individuals. In this study, we performed a systematic...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.13015

    authors: Li W,Mao Z,Bo Q,Sun Y,Wang Z,Wang C

    更新日期:2020-07-24 00:00:00

  • Integrating primary care and early intervention in psychosis services: a general practitioner perspective.

    abstract:AIMS:Earlier detection and treatment of psychosis is associated with improved health outcomes. While the role of specialist services to facilitate early diagnosis and treatment has been extensively described internationally, little data on their impact on general practice has been reported. A new specialist service for...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/j.1751-7893.2008.00065.x

    authors: Gavin B,Cullen W,Foley S,McWilliams S,Turner N,O'Callaghan E,Bury G

    更新日期:2008-05-01 00:00:00

  • Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong.

    abstract:AIM:The current study explored the effect of an early intervention (EI) service for psychosis in Hong Kong (EASY) on the reduction of the duration of untreated psychosis (DUP) at 10 years, in adolescent and adult patients. METHOD:Data from three first-episode psychosis (FEP) studies conducted over 10 years using the s...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12313

    authors: Chan SKW,Chau EHS,Hui CLM,Chang WC,Lee EHM,Chen EYH

    更新日期:2018-06-01 00:00:00

  • Managing disclosure following recent-onset psychosis: utilizing the individual placement and support model.

    abstract:AIMS:Individual Placement and Support is the most defined and evidence-based approach to supported employment for severe mental illness, including recent-onset psychosis. However, there is limited evidence or detailed guidelines informing the management of mental illness disclosure to educators or employers when delive...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12030

    authors: Allott KA,Turner LR,Chinnery GL,Killackey EJ,Nuechterlein KH

    更新日期:2013-08-01 00:00:00

  • Social network confidants, duration of untreated psychosis and cannabis use in people with first episode psychosis: An exploratory study.

    abstract:AIM:Reduced social network (SN) might be associated with a longer duration of untreated psychosis (DUP) in people with first episode psychosis (FEP). We aimed at exploring the specific role of SN confidants on DUP, taking into account cannabis misuse, which is known to influence DUP and might be associated with social ...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12476

    authors: Carrà G,Battaglia C,Hinton M,Sheridan Rains L,Crocamo C,Johnson S

    更新日期:2018-10-01 00:00:00

  • The role of youth mental health services in the treatment of young people with serious mental illness: 2-year outcomes and economic implications.

    abstract:AIM:This study aims to evaluate the outcomes and economic case for a UK innovative youth-specific mental health service for 16-25 year olds. METHODS:A pre-, during- and post-treatment comparative design for 20 young people at high risk of developing psychosis who received 2 years' treatment with the service, using out...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12261

    authors: Brimblecombe N,Knapp M,Murguia S,Mbeah-Bankas H,Crane S,Harris A,Evans-Lacko S,Ardino V,Iemmi V,King D

    更新日期:2017-10-01 00:00:00

  • Figural fluency and immediate visual memory in patients with at-risk mental state for psychosis: empirical study.

    abstract:AIM:Although a number of cognitive functions have been assessed in the ultra-high risk (UHR) population, only one study has reported on figural fluency. Visual memory was measured by different tests providing inconsistent results. The aim of the present study was to compare figural fluency and visual immediate memory p...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12116

    authors: Pawełczyk A,Kotlicka-Antczak M,Rabe-Jabłońska J,Pawełczyk T,Ruszpel A,Łojek E

    更新日期:2015-08-01 00:00:00

  • Destigmatizing psychosis: Investigating the effectiveness of a school-based programme in Hong Kong secondary school students.

    abstract:AIM:Although the reasons behind the stigmatization of psychosis are manifold, poor mental health literacy among the general public is likely to be a major factor. In Hong Kong, the Early Psychosis Foundation (EPISO) was established in 2007 to tackle this issue by providing educational and mental health promotional acti...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章

    doi:10.1111/eip.12692

    authors: Hui CLM,Leung WWT,Wong AKH,Loong KY,Kok J,Hwang A,Lee EHM,Chan SKW,Chang WC,Chen EYH

    更新日期:2019-08-01 00:00:00

  • Negative symptoms of psychosis: A life course approach and implications for prevention and treatment.

    abstract:AIM:Negative symptoms are a cause of enduring disability in serious mental illness. In spite of this, the development of effective treatments for negative symptoms has remained slow. The challenge of improving negative symptom outcomes is compounded by our limited understanding of their aetiology and longitudinal devel...

    journal_title:Early intervention in psychiatry

    pub_type: 杂志文章,评审

    doi:10.1111/eip.12501

    authors: Lyne J,O'Donoghue B,Roche E,Renwick L,Cannon M,Clarke M

    更新日期:2018-08-01 00:00:00