Abstract:
AIM:Negative symptoms are a cause of enduring disability in serious mental illness. In spite of this, the development of effective treatments for negative symptoms has remained slow. The challenge of improving negative symptom outcomes is compounded by our limited understanding of their aetiology and longitudinal development. METHODS:A literature search was conducted for life course approach of negative symptoms using PubMed. Further articles were included following manual checking of reference lists and other search strategies. The paper contains a theoretical synthesis of the literature, summarized using conceptual models. RESULTS:Negative symptom definitions are compared and considered within a context of the life course. Previous studies suggest that several illness phases may contribute to negative symptoms, highlighting our uncertainty in relation to the origin of negative symptoms. CONCLUSIONS:Similar to other aspects of schizophrenia, negative symptoms likely involve a complex interplay of several risk and protective factors at different life phases. Concepts suggested in this article, such as "negative symptom reserve" theory, require further research, which may inform future prevention and treatment strategies.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Lyne J,O'Donoghue B,Roche E,Renwick L,Cannon M,Clarke Mdoi
10.1111/eip.12501subject
Has Abstractpub_date
2018-08-01 00:00:00pages
561-571issue
4eissn
1751-7885issn
1751-7893journal_volume
12pub_type
杂志文章,评审abstract:AIM:Potential differences in psychiatric clinical outcomes and hospitalization rates before and after the initiation of long-acting risperidone among recently and long-term diagnosed schizophrenia patients were studied. METHODS:Data from two observational studies (Trial for the Initiation and Maintenance Of REmission ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12017
更新日期:2014-02-01 00:00:00
abstract:AIM:Self-determination theory (SDT) has demonstrated that human well-being is associated with the satisfaction of three basic psychological needs (ie, autonomy, competence and relatedness)-with more recent research highlighting the applicability of SDT to individuals with first-episode psychosis (FEP). These findings s...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12784
更新日期:2019-12-01 00:00:00
abstract:AIMS:Most programs specializing in the treatment of first-episode psychosis in the United States focus on schizophrenia. However, many early psychosis patients do not fit into this diagnostic category. Here we describe McLean OnTrack, an intensive outpatient treatment program that accepts all comers with first-episode ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12299
更新日期:2017-02-01 00:00:00
abstract:AIM:This study aims to evaluate the outcomes and economic case for a UK innovative youth-specific mental health service for 16-25 year olds. METHODS:A pre-, during- and post-treatment comparative design for 20 young people at high risk of developing psychosis who received 2 years' treatment with the service, using out...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12261
更新日期:2017-10-01 00:00:00
abstract:AIM:The early intervention (EI) model appears to improve outcomes of psychosis for younger people, and there is now interest in implementing it in older groups. In the UK, the National Institute of Clinical Excellence advised that EI should be accessible to all individuals with first episode psychosis (FEP). We aimed t...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12322
更新日期:2018-06-01 00:00:00
abstract:AIM:This study explores the mental health needs of teachers and how these might impact on their capacity to provide early identification and intervention strategies to support their student's emotional well-being. METHOD:The present study surveyed a sample of UK teachers (N = 320) to explore the impact of work-related...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12264
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Those with serious mental illness (SMI) including both psychotic and affective disorders are recognized to have a premature mortality compared to the general population, at least in part due to elevated cardiovascular risk profile. AIM:To examine the effect of a 12-week, pragmatic, sustainable, low-cost int...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12965
更新日期:2020-04-26 00:00:00
abstract:AIM:The duration of untreated psychosis (DUP) refers to the period of time between the emergence of psychotic symptoms and the initiation of appropriate clinical treatment. Prolonged DUP is associated with a range of adverse consequences, including more severe illness course, cognitive deficits and poor functioning. Pr...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12308
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:The onset of psychosis typically occurs during adolescence or early adulthood and can have a detrimental impact on social and cognitive development. Cognitive behavioural therapy (CBT) shows promise in reducing the risk of psychosis. Teaching families to apply CBT with their offspring may bolster therapeutic ...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12204
更新日期:2016-12-01 00:00:00
abstract:AIM:Ultrahigh risk (UHR) criteria, consisting of brief limited intermittent psychotic symptoms (BLIPS), attenuated psychotic symptoms (APS) and genetic risk and deterioration (GRD) syndrome are the most widely used criteria for assessing the clinical high-risk state for psychosis (CHR-P). The Basel Screening Instrument...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12719
更新日期:2019-08-01 00:00:00
abstract:AIM:It is unclear how adult mindfulness-based interventions (MBIs) should be modified for youth, and at what ages programmes should be implemented for optimal impact. Recent non-replication with a 9-week programme in early adolescence suggested abbreviated programme content might be insufficient and/or that this age gr...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12801
更新日期:2019-12-01 00:00:00
abstract:AIMS:Earlier detection and treatment of psychosis is associated with improved health outcomes. While the role of specialist services to facilitate early diagnosis and treatment has been extensively described internationally, little data on their impact on general practice has been reported. A new specialist service for...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2008.00065.x
更新日期:2008-05-01 00:00:00
abstract:AIM:Although a number of cognitive functions have been assessed in the ultra-high risk (UHR) population, only one study has reported on figural fluency. Visual memory was measured by different tests providing inconsistent results. The aim of the present study was to compare figural fluency and visual immediate memory p...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12116
更新日期:2015-08-01 00:00:00
abstract:AIM:Early intervention programmes for first episode psychosis (FEP) aim to reduce the duration of untreated psychosis (DUP) and improve functional outcomes. The sustained maintenance of improved outcomes depends largely on patients' adherence to prescribed treatment. This paper examines the prevalence of non-adherence ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12559
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:This article describes the development of the smartphone application for cognitive-behavioural case management of young individuals with early psychosis and examines the acceptance and potential clinical benefits of this application through a pilot survey. METHODS:Gwangju Bukgu-Community Mental Health Cente...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12418
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Despite recent focus on developing family-inclusive services to meet the needs of young people with first-episode psychosis, the needs of their siblings are often overlooked. AIMS:This study explored the experiences and needs of siblings of young adults with first-episode psychosis receiving support from tw...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00300.x
更新日期:2012-02-01 00:00:00
abstract:AIM:Family interventions are a core component of first-episode psychosis (FEP) treatment; however, low implementation rates are consistently reported. As such, work is needed to understand the factors impacting real-world treatment delivery. The present paper describes the implementation of the McFarlane-model multifam...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13066
更新日期:2020-11-08 00:00:00
abstract:AIM:The aim of this study was to describe the development of a sustainable community early psychosis programme created through an academic-community partnership in the United States to other parties interested in implementing early psychosis services founded upon evidence-based practices within community settings. MET...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00310.x
更新日期:2011-11-01 00:00:00
abstract::Young people attempting to access mental health services in the United Kingdom often find traditional models of care outdated, rigid, inaccessible and unappealing. Policy recommendations, research and service user opinion suggest that reform is needed to reflect the changing needs of young people. There is significant...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12452
更新日期:2018-08-01 00:00:00
abstract:AIM:Most studies on the determinants of psychosocial functioning in first-episode psychosis used few predictors. This study examines the effects of multiple cognitive domains and multiple symptoms on psychosocial functioning. METHODS:A total of 162 patients with a first-episode psychosis were assessed within 3 months ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12210
更新日期:2017-02-01 00:00:00
abstract:AIM:Previous research has demonstrated a strong association between early trauma exposure and the development of psychotic symptoms. However, few of these studies have included young adolescents and children. This study investigated rates and number of potentially traumatic experiences (PTEs) among typically developing...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12565
更新日期:2019-08-01 00:00:00
abstract:AIM:To determine duration of untreated psychosis (DUP) in patients with schizophrenia-spectrum disorders from Serbia and to analyse factors that potentially contribute to the treatment delay, with focus on personality traits. METHODS:Fifty seven patients (males 54.4%; age = 29.9 ± 6.0 yrs; age at the illness onset = 2...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12348
更新日期:2018-02-01 00:00:00
abstract:AIM:To increase our understanding of substance use among adolescents with psychosis by comparing their reasons for use with those of typically developing adolescents. METHODS:Participants were 35 outpatient adolescents, recently admitted for a first episode of psychosis to an early psychosis programme, and 35 typicall...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2007.00055.x
更新日期:2008-02-01 00:00:00
abstract:AIM:Despite the potential benefits of e-health interventions for patients with psychosis, the integration of these applications into the clinical workflow and analysis of their long-term effects still face significant challenges. To address these issues, we developed the ReMindCare app. This app aims to improve the tre...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12960
更新日期:2021-02-01 00:00:00
abstract:AIM:A longer duration of untreated psychosis (DUP) is associated with greater morbidity in the early course of schizophrenia. This formative, hypothesis-generating study explored the effects of stigma, as perceived by family members, on DUP. METHODS:Qualitative interviews were conducted with 12 African American family...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2009.00155.x
更新日期:2010-02-01 00:00:00
abstract:AIM:The Meals, Mindfulness, & Moving Forward (M3 ) programme included nutrition education, hands-on cooking classes, mindfulness meditation practice, physical activities and facilitated group sharing. M3 was designed as a supplement to standard care for youths (age 15-25 years) with first-episode psychosis (FEP) who we...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12913
更新日期:2021-02-01 00:00:00
abstract:AIMS:This report discusses the use of antinuclear antibody (ANA) detection as a screening test for neuropsychiatry systemic lupus erythematosus (NPSLE) in patients presenting a first-episode psychosis. METHODS:We reviewed the medical records of 85 patients admitted to an emergency service due to first-episode psychosi...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00339.x
更新日期:2012-08-01 00:00:00
abstract:AIM:This study aimed to explore the presence of psychotic like experience (PLE) symptoms and evaluate for the possible socio-demographic, family, school and mental health variables associated with clinically significant PLE symptoms in Nigeria school adolescent. METHODS:A total of 9441 adolescents from 47 secondary sc...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13032
更新日期:2020-09-02 00:00:00
abstract:AIM:Neurophysiological markers of schizophrenia may help identify individuals who are at an increased risk of developing psychosis. As an operational measure of sensorimotor gating, pre-pulse inhibition (PPI) deficit has been investigated in clinical high-risk (CHR) individuals. In this study, we performed a systematic...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13015
更新日期:2020-07-24 00:00:00
abstract:AIM:The current study explored the effect of an early intervention (EI) service for psychosis in Hong Kong (EASY) on the reduction of the duration of untreated psychosis (DUP) at 10 years, in adolescent and adult patients. METHOD:Data from three first-episode psychosis (FEP) studies conducted over 10 years using the s...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12313
更新日期:2018-06-01 00:00:00