Abstract:
AIMS:Most programs specializing in the treatment of first-episode psychosis in the United States focus on schizophrenia. However, many early psychosis patients do not fit into this diagnostic category. Here we describe McLean OnTrack, an intensive outpatient treatment program that accepts all comers with first-episode psychosis. METHODS:We assessed baseline characteristics of patients in the 2.5 years since program initiation. We examined how initial referral diagnoses compare with current diagnoses, calculating the proportion of diagnostic changes. RESULTS:At 2.5 years, patients in McLean OnTrack consist of 30 (33.0%) individuals with primary psychotic disorder, 40 (44.0%) with affective psychosis, 19 (20.9%) with psychotic disorder not otherwise specified (NOS) who do not meet full criteria for either category and two (2.2%) individuals with no psychosis. Although patients with affective psychosis had higher pre-morbid functioning, all three categories of psychosis had similar rates of prior hospitalizations and substance use. The retention rate in the psychotic disorder NOS group was lower than that in affective and primary psychotic disorders. Finally, diagnoses changed over the course of treatment in 50.5% of patients. CONCLUSIONS:Diagnostic heterogeneity appears to be the norm among patients with first-episode psychosis, and diagnoses commonly evolve over the illness course. Baseline indices of illness severity were similar across categories and suggest the need for early intervention, irrespective of specific diagnosis. We discuss the benefits and challenges of a transdiagnostic approach to early intervention in first-episode psychosis, treating patients who share many but not all characteristics.
journal_name
Early Interv Psychiatryjournal_title
Early intervention in psychiatryauthors
Shinn AK,Bolton KW,Karmacharya R,Lewandowski KE,Yuksel C,Baker JT,Chouinard VA,Pingali SM,Bye H,Cederbaum K,Öngür Ddoi
10.1111/eip.12299subject
Has Abstractpub_date
2017-02-01 00:00:00pages
83-90issue
1eissn
1751-7885issn
1751-7893journal_volume
11pub_type
杂志文章abstract:AIM:It is unclear how adult mindfulness-based interventions (MBIs) should be modified for youth, and at what ages programmes should be implemented for optimal impact. Recent non-replication with a 9-week programme in early adolescence suggested abbreviated programme content might be insufficient and/or that this age gr...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12801
更新日期:2019-12-01 00:00:00
abstract:AIM:Children and adolescents with bipolar parents have an elevated risk for anxiety disorders. However, antidepressant medications commonly used to treat symptoms of anxiety may accelerate the onset of mania in these already at-risk youth. Therefore, studies evaluating innovative non-pharmacologic treatments for anxiet...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12216
更新日期:2016-10-01 00:00:00
abstract:AIM:Looking after someone in the early stages of psychosis can have a negative impact on caregivers, but there is little clarity about which interventions, if any, caregivers should be offered. This study investigated sleep disturbances in early psychosis caregivers and the relationship between their sleep quality and ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12538
更新日期:2019-06-01 00:00:00
abstract:AIM:Prior to the release of the fifth edition of the Diagnostic and Statistical Manual for Mental Disorders, experts in the field of psychosis research considered including a psychosis high-risk syndrome-attenuated psychosis syndrome-as a formal diagnosis. Opponents argued that such a diagnosis may increase the risk of...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12710
更新日期:2019-08-01 00:00:00
abstract:AIM:A longer duration of untreated psychosis (DUP) is associated with greater morbidity in the early course of schizophrenia. This formative, hypothesis-generating study explored the effects of stigma, as perceived by family members, on DUP. METHODS:Qualitative interviews were conducted with 12 African American family...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2009.00155.x
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abstract:AIM:The study aims to examine the themes of delusions and hallucinations in a cohort of adolescent and young adult patients (aged 15-26 years) presenting with a first episode of psychosis. METHODS:Information was collected retrospectively from 143 randomly selected medical files, using a questionnaire. RESULTS:Over 7...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2011.00281.x
更新日期:2011-08-01 00:00:00
abstract:AIM:Although the reasons behind the stigmatization of psychosis are manifold, poor mental health literacy among the general public is likely to be a major factor. In Hong Kong, the Early Psychosis Foundation (EPISO) was established in 2007 to tackle this issue by providing educational and mental health promotional acti...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12692
更新日期:2019-08-01 00:00:00
abstract:AIM:Gender differences in the current symptomatology of patients with psychotic disorders have previously been described in the literature. However, it has not yet been investigated whether gender differences exist in the very first self-perceived signs or symptoms of illness onset. The aim of this study was to investi...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12528
更新日期:2019-06-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12831
更新日期:2020-02-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/j.1751-7893.2012.00373.x
更新日期:2012-11-01 00:00:00
abstract::Young people use social media to communicate about suicide, however, they often feel ill-equipped to share their own experiences or to respond to expressions of risk by others. AIMS:To describe the adaptation of the Australian #chatsafe guidelines for an international audience, and their initial roll out via social m...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.13044
更新日期:2020-09-15 00:00:00
abstract:AIM:Youth at clinical high risk (CHR) for psychosis often exhibit difficulties in social functioning and poorer social functioning may be predictive of transition to a psychotic disorder. Therefore, the primary objective of this systematic review was to summarize the impact of all interventions on social functioning in...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,meta分析
doi:10.1111/eip.12689
更新日期:2019-04-01 00:00:00
abstract:AIM:This study aims to evaluate the outcomes and economic case for a UK innovative youth-specific mental health service for 16-25 year olds. METHODS:A pre-, during- and post-treatment comparative design for 20 young people at high risk of developing psychosis who received 2 years' treatment with the service, using out...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12261
更新日期:2017-10-01 00:00:00
abstract:AIM:The Meals, Mindfulness, & Moving Forward (M3 ) programme included nutrition education, hands-on cooking classes, mindfulness meditation practice, physical activities and facilitated group sharing. M3 was designed as a supplement to standard care for youths (age 15-25 years) with first-episode psychosis (FEP) who we...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12913
更新日期:2021-02-01 00:00:00
abstract:AIM:Early Intervention Psychosis Services (EIPS) for people experiencing First Episode Psychosis (FEP) offer important clinical and non-clinical benefits over standard care. Similarly, intervention for Clinical High Risk for Psychosis state (CHR-P) can prevent psychosis, ameliorate symptoms and have non-clinical benefi...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12787
更新日期:2019-12-01 00:00:00
abstract:AIM:There is a long-standing interest in the relationship between patients affected by psychosis and their families. Previous research also suggests that perceived family dysfunction is a factor commonly associated with psychological problems in adolescence. The current study examined the role of self-reported family p...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12115
更新日期:2015-08-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12939
更新日期:2020-02-11 00:00:00
abstract:AIM:The objective of the study was to investigate high school teacher's literacy on psychosis symptoms and teachers' confidence in the positive effects of psychosis treatment on the mental health of students with psychotic symptoms at two sites: one site with an extensive early detection of psychosis programme includin...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2010.00248.x
更新日期:2011-05-01 00:00:00
abstract:AIM:In psychotic disorders, a limited number of studies have documented the presence of symptoms of anxiety, especially in first-episode psychosis (FEP). There is a growing interest in better understanding how these symptoms may affect the severity of psychotic symptoms and clinical outcome. This study examined the ass...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12018
更新日期:2013-02-01 00:00:00
abstract:AIM:Psychiatric comorbidity frequently occurs with at-risk mental state (ARMS) for psychosis. Its relationships with psychopathology, cognition and functioning, however, remain to be further clarified. We aimed to examine prevalence and correlates of psychiatric comorbidity, and its associations with psychosocial funct...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12992
更新日期:2020-05-22 00:00:00
abstract:OBJECTIVE:The onset of psychosis typically occurs during adolescence or early adulthood and can have a detrimental impact on social and cognitive development. Cognitive behavioural therapy (CBT) shows promise in reducing the risk of psychosis. Teaching families to apply CBT with their offspring may bolster therapeutic ...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12204
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abstract:AIM:Conduct a systematic review for the effectiveness of school mental health literacy programs to enhance knowledge, reduce stigmatizing attitudes and improve help-seeking behaviours among youth (12-25 years of age). METHODS:Reviewers independently searched PubMed, PsycINFO, Cochrane Library, CINAHL, ERIC, grey liter...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/eip.12010
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12083
更新日期:2014-08-01 00:00:00
abstract:AIM:In contrast to affective disorders, some forms of personality disorders and drug addiction, schizophrenia is commonly not considered to be a sequela of attention deficit hyperactivity disorder. However, attention deficit hyperactivity disorder and the prodromal stages of schizophrenia spectrum disorders do exhibit ...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,评审
doi:10.1111/j.1751-7893.2011.00293.x
更新日期:2012-02-01 00:00:00
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journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12452
更新日期:2018-08-01 00:00:00
abstract:AIM:This paper aims to identify the ways in which youth at ultra high risk for psychosis access mental health services and the factors that advance or delay help seeking, using the Revised Network Episode Model (REV NEM) of mental health care. METHODS:A case study approach documents help-seeking pathways, encompassing...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2012.00350.x
更新日期:2013-05-01 00:00:00
abstract:AIM:A modular symptom-specific (MSS) programme of early intervention group cognitive behaviour therapy for psychosis might confer additional therapeutic benefits and clinical and financial efficiency, but the approach is empirically untested. Therefore, we devised a novel MSS programme to test - in a culturally diverse...
journal_title:Early intervention in psychiatry
pub_type: 临床试验,杂志文章
doi:10.1111/eip.12025
更新日期:2013-05-01 00:00:00
abstract:AIM:Adolescents with psychotic disorders show deficits in IQ, attention, learning and memory, executive functioning, and processing speed that are related to important clinical variables including negative symptoms, adaptive functioning and academics. Previous studies have reported relatively consistent deficits with v...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/j.1751-7893.2008.00075.x
更新日期:2008-08-01 00:00:00
abstract:AIM:Improvement of social adjustment is a major aim of indicated prevention in young people at risk of developing psychosis. The present study explores the effect of specific cognitive behaviour therapy (CBT) as compared with supportive counselling (SC) on social adjustment in people in a potential early initial prodro...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1751-7893.2007.00013.x
更新日期:2007-02-01 00:00:00
abstract:AIM:Although models of family intervention are clearly articulated in the child and early adolescent literature, there is less clarity regarding family intervention approaches in later adolescence and emerging adulthood. METHODS:This study provides the rationale and intervention framework for a developmentally sensiti...
journal_title:Early intervention in psychiatry
pub_type: 杂志文章
doi:10.1111/eip.12383
更新日期:2018-04-01 00:00:00