Abstract:
BACKGROUND:Acne vulgaris is the most common inflammatory sebaceous gland disorder in young adults. The resistant strains of Propionibacterium acnes (P. acnes) are of increasing concern in the treatment of acne. OBJECTIVES:To evaluate the efficacy of 0.5% topical mangosteen extract in nanoparticle loaded gel (containing alpha-mangostin) compared with 1% clindamycin gel for treatment of mild-to-moderate acne vulgaris. METHODS:Patients aged 18-40 years were enrolled in this double-blinded, split-face, randomized, control study. The 2.5% benzoyl peroxide cream was applied to both sides of the faces once daily for 5 minutes and washed off. Each patient was randomly treated with the mangosteen fruit rind extract on one side and 1% clindamycin on another side of the face twice daily for 12 weeks. Treatment efficacies and side effects were evaluated on every follow-up. RESULTS:Twenty-eight patients, 24 female (85.7%), mean ± SD age of 25.14 ± 5.8, with Global Acne Grading system (GAGs) score of 15.43 ± 5.96 were included. Mangosteen fruit rind extract significantly showed significant 66.86% and 67.05% reduction of comedone and inflammatory lesions (P < 0.001) after 12-week treatment. The improvement on both treated sides significantly showed since 2 weeks after treatment, without statistical difference between two groups. Nonetheless, the mangosteen fruit rind extract revealed significantly better improvement of clinical severity, with no severe side effects. CONCLUSIONS:The mangosteen fruit rind extract formation could be a phytopharmaceutical medication for effective treatment of mild and moderate acne vulgaris treatment comparable to 1% clindamycin gel, with no severe side effects.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Lueangarun S,Sriviriyakul K,Tempark T,Managit C,Sithisarn Pdoi
10.1111/jocd.12856subject
Has Abstractpub_date
2019-01-27 00:00:00eissn
1473-2130issn
1473-2165pub_type
杂志文章abstract::We described-along with a genetic predisposition and exposure to sunlight, as the main factors for melasma development-pregnancy, hormonal therapies, and oral contraceptive pills. Whilst hormonal alteration or therapies are frequently reported in literature in association with melasma, studies analyzing the laboratori...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/jocd.12877
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Human skin aging is caused by several factors, such as UV irradiation, stress, hormone, and pollution. Wrinkle formation and skin pigmentation are representative features of skin aging. Although EGF and arbutin are used as anti-wrinkle and skin whitening agents, respectively, they have adverse effects on ski...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12671
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Acne vulgaris in females may be resistant to treatment in spite of topical and systemic therapy for a sufficient period. In this condition, acne may be a manifestation of underlying endocrine conditions such as polycystic ovary syndrome (PCOS). OBJECTIVE:To evaluate the frequency of PCOS in females with res...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2010.00500.x
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Clinical outcomes of eyebrow restoration with single-follicular-unit hair transplantation largely depend on the surgeon's anatomic knowledge, experience, and technical skills. AIMS:To evaluate the effect of the reconstruction with single follicular unit transplantation on eyebrow loss and provide technical ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13242
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION:Plantar warts are associated with high transmissibility and morbidity. Among the available therapeutic options, none is uniformly effective or virucidal. Salicylic acid is the first-line therapy but approximately one-third of lesions could not resolve and become recalcitrant despite repeated treatment. Cry...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13102
更新日期:2020-04-01 00:00:00
abstract::We report the case of a woman who presented with several facial scars following a road accident. Treatment was carried out using combined laser treatment with pulsed dye laser (PDL) and Q-switched neodymium:yttrium-aluminum-garnet laser (QS Nd:YAG laser). No side effects or complications from treatment were noted or r...
journal_title:Journal of cosmetic dermatology
pub_type: 信件
doi:10.1111/j.1473-2165.2008.00394.x
更新日期:2008-09-01 00:00:00
abstract::Cosmetic defects of the nail cover a range of changes. Some are variants of normal which are considered unattractive, others are part of the normal ageing process and some changes are manifestations of local or systemic disease. Interpretation of these changes relies on recognition of the specific characteristics in q...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1046/j.1473-2130.2001.00014.x
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Since air pollution is only one of many environmental stressors that can affect skin, it has been challenging to identify skin appearance or functional features profoundly affected by chronic exposure to traffic-derived air pollution. AIMS:The current population study focused on taxi drivers working in urba...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13194
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Rosacea is a chronic skin condition that typically affects the face and it results in redness and inflammation. The main risk factors of this disease are Demodex folliculorum, living in the pilosebaceous units. AIMS:To evaluate the efficacy and safty of permethrin 2.5% in combination with tea tree oil (TTO)...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
abstract::Today, most do not go a day without practicing or hearing about new hair removal methods. However, little is discussed about the history of hair removal and the development of most hair removal methods since the period of cavemen. Avoiding decapitation and fitting in with society are two of many reasons for the develo...
journal_title:Journal of cosmetic dermatology
pub_type: 历史文章,杂志文章
doi:10.1111/jocd.12021
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Infraorbital dark circles (DC) are defined as a symptom that presents darkness under infraorbital eyelids. The objective of this study was to evaluate the efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol (PR) for the treatment of infraorbital dark circles. METHODS:Twenty female partic...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13641
更新日期:2020-08-11 00:00:00
abstract:BACKGROUND:The aging process affects all organs of the body, but the skin is the most visible indicator with a great psychosocial impact. As a consequence, many skin anti-aging strategies have been developed to minimize, postpone, and even reverse the aging process. Growth factors have been widely studied in skin wound...
journal_title:Journal of cosmetic dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/jocd.12771
更新日期:2019-06-01 00:00:00
abstract:INTRODUCTION:The ideal filler should be long-lasting, biocompatible, chemically inert, soft and easy to use, and have a long history of safety. This review focuses on the evolution and development of the PMMA-collagen gel, Bellafill, and the 10 years of postmarketing experience of Bellafill since it received premarket ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
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更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Spiny keratoderma shows "music box spine" keratotic papules limited to the palms and soles and these lesions do not cause any trouble besides the cosmetic impairment and the sensation of roughness of hands and soles. AIM:To present cases and review the literature on spiny keratoderma. PATIENTS/METHODS, RES...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13248
更新日期:2020-08-01 00:00:00
abstract::Recently, both doctors and patients pay particular attention to aesthetic medical services quality and efficacy of aesthetic adjustment implemented. It is essential to ensure research, analysis, and improving of botulinum toxin therapy quality and provide patients' orientation on the adjustment schedule, which include...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13584
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Adolescent and young adult melanomas show different histopathological characteristics and clinical behaviors from adult melanomas. OBJECTIVE:To describe the histopathological and clinical features pertinent to vicenarian skin melanomas and compare them with adult melanomas using a large cohort from a single...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13314
更新日期:2020-01-31 00:00:00
abstract:BACKGROUND:Spitzoid melanoma is one of the rare subtypes of melanoma, whose clinical and pathological characteristics have yet to be understood. OBJECTIVE:Understanding the histopathologic features and behavior characteristics of Spitzoid cutaneous melanoma. METHODS:A total number of 11 Turkish Caucasian patients wit...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12958
更新日期:2019-12-01 00:00:00
abstract::Botulinum toxin type A is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It has been used extensively in the field of dermatology for the treatment of dynamic rhytides and in the treatment of hyperhidrosis. Botulinum toxin has an excellent safety profile and few s...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2006.00255.x
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Due to the ever-increasing demands for the personalized care, people seek for the tailored management according to the accurate identification of their skin type. The Baumann Skin Type Indicator, which was proposed by Leslie Baumann, is composed of four parameters: oily or dry, resistant or sensitive, pigmen...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/jocd.13347
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Infantile hemangiomas (IHs) are the most common soft tissue tumors of infancy. Although spontaneous regression is expected, medical treatment is needed in approximately 10-20% of cases. AIMS:We aimed to assess the safety and efficacy of systemic propranolol for the treatment of IH. PATIENTS/METHODS:Medical...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Hyaluronic acid fillers are known to be effective for correction of nasolabial folds. Recently, a novel biphasic hyaluronic acid filler incorporating lidocaine, DIVAVIVA medium has been introduced. OBJECTIVES:We compared the efficacy and safety between DIVAVIVA medium and Restylane Perlane Lidocaine for mod...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13773
更新日期:2020-10-08 00:00:00
abstract::To review indexed literature concerning adverse ocular effects of the most common aesthetic facial procedures (light-emitting therapy, dermal fillers injection, and botulinum toxin). Literature search using three online databases - PubMed, SciELO, and Capes - selecting case reports, series of cases and reviews, with n...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/jocd.12141
更新日期:2015-06-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13075
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Microdermabrasion is a nonchemical superficial resurfacing procedure that removes the stratum corneum. Because it is a somewhat subtle procedure, it may be difficult to demonstrate its cosmetic benefit. OBJECTIVES:To assess the efficacy of microdermabrasion in treatment of melasma, postacne scarring, striae...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12827
更新日期:2019-02-01 00:00:00
abstract::Melasma is an acquired hypermelanosis that results in localized hyperpigmentation, commonly found on the face. This condition is much more common in women than men. There are some features of melasma in men that seem to differ from those seen in women. However, there is a paucity of data on this topic. The aim of this...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2012.00613.x
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The sebaceous gland and the follicular bulge region have important role in biology of the hair. They initiate destruction of the hair follicle both in human and animal models in certain conditions. The morphometric feature of the sebaceous gland is not well understood so as the distribution of the bulge stem...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12153
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:UV filters should be determined a strict toxicological safety prior to approval. Homosalate (HMS) is one of the most widely used organic UV filter. HMS accumulates in aquatic biota ecosystems and humans through the food chain; therefore, it is important to consider the effects on health and know its mechanis...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Masseter hypertrophy is a common, prominent feature in many Asian patients, and correction procedures are often requested for esthetic reasons. Toxin masseter injections have a high efficacy and safety profile, but the risks of a variety of side effects or complications remain. OBJECTIVES:The categorization...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.12473
更新日期:2018-02-01 00:00:00
abstract::A 23-year-old left-handed white male was referred with a complaint of brown discolouration of the fingernails of his left hand. He had been applying 4% hydroquinone cream to facial melasma. The discolouration began in winter and worsened in March and April. It resolved within 2 months of cessation of hydroquinone. The...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2130.2004.00085.x
更新日期:2003-07-01 00:00:00