Abstract：
BACKGROUND:Spitzoid melanoma is one of the rare subtypes of melanoma, whose clinical and pathological characteristics have yet to be understood. OBJECTIVE:Understanding the histopathologic features and behavior characteristics of Spitzoid cutaneous melanoma. METHODS:A total number of 11 Turkish Caucasian patients with pathologically diagnosed Spitzoid melanoma were analyzed retrospectively. RESULTS:The median age of patients was 24 years (ranging from 16 to 54 years), and the females outnumbered the males (90%). The extremities, especially lower limbs (67%), were the most commonly affected primary areas (64% of patients). Median depth and mitotic rate were 2.2 mm and 3 /mm2 , respectively. The presence of ulceration and regression were observed in a few lesions (14%). While tumor-infiltrating lymphocytes were expressed in all of the lesions, none of the lesions was associated with lymphovascular invasion and/or neurotropism. The regional lymph nodes were involved only in minority of the patients (27%), and no patients had metastatic disease. Recurrences occurred in only two patients (18%) that affected merely distant areas, that is, lung and brain. The median disease-free survival time and 5-year disease-free survival rate were 20.5 months and 80.6%, respectively. Only one (9%) death occurred; and the median overall survival time was 26.2 months, and 5-year overall survival rate was 90.7%. CONCLUSION:Spitzoid cutaneous melanoma is correlated with favorable histopathologic and clinical characteristics, and therefore, it is associated with better survival rates.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Tas F,Erturk Kdoi
10.1111/jocd.12958subject
Has Abstractpub_date
2019-12-01 00:00:00pages
1841-1845issue
6eissn
1473-2130issn
1473-2165journal_volume
18pub_type
杂志文章abstract：:Skin aging (intrinsic aging) and photoaging (extrinsic aging) involve a similar process that leads to the typical creased appearance of the skin, with the progressive loss of its physical and biologic properties. Photoaging is a premature skin aging caused by long-term exposure to the ultraviolet B radiations of the s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2005.00198.x
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Argyria results from silver accumulation in the skin. It is a stressful condition for patients due to skin discoloration. In the past, no effective treatments were available. However, it has been recently reported laser treatments showed promising results. AIM:To review and summarize all reported laser trea...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.13549
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Acne vulgaris is a highly prevalent skin condition associated with considerable psychological burden. Acne and its sequelae can affect many domains of life leading to social dysfunction, psychiatric issues and educational shortcomings. Psychiatric conditions like depression is found to be more prevalent in a...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.13753
更新日期：2020-12-01 00:00:00
abstract：:Twin studies, especially those involving monozygotic (MZ) twins, facilitate the analysis of factors affecting skin aging while controlling for age, gender, and genetic susceptibility. The purpose of this study was to objectively assess various features of facial skin and analyze the effects of environmental factors on...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12081
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Blue light from electronic devices enriched with a peak at 456 nm affects circadian rhythm and antioxidant balance of skin, necessitating the study of photoprotection against the 456-nm blue light. AIMS:This study aims to report that blue light (456 nm) can cause skin pigmentation and proposes a new clinica...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13508
更新日期：2020-09-01 00:00:00
abstract：:Nutracosmetics are an emerging class of health and beauty aid products that combine the benefits of nutracosmetical ingredients with the elegance, skin feel, and delivery systems of cosmetics. Herbs and spices have been used in maintaining and enhancing human beauty because herbs have many beneficial properties, such ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2008.00369.x
更新日期：2008-06-01 00:00:00
abstract：:Botulinum toxin type A is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It has been used extensively in the field of dermatology for the treatment of dynamic rhytides and in the treatment of hyperhidrosis. Botulinum toxin has an excellent safety profile and few s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2006.00255.x
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:Brittle nail syndrome is a common problem among women and refers to nails that exhibit surface roughness, raggedness, and peeling. AIM:The goal of this study was to investigate whether daily oral supplementation with collagen peptides alleviates the symptoms of brittle nails and improves nail growth rate. ...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.12393
更新日期：2017-12-01 00:00:00
abstract：:Moisturizers are used on large body surfaces to maintain the smoothness of the skin and to break the dry-skin cycle. Many healthcare professionals and patients overlook the importance of moisturizers and do not consider them to be 'active' treatments. However, evidence from clinical and experimental studies shows that...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2130.2004.00062.x
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:There remains the need for more effective therapeutic options to treat acne vulgaris. Interest in light-based acne treatments has increased, but few randomized, controlled clinical trials assessing the value of photodynamic therapy (PDT) for acne have been reported. AIMS:We sought to examine the efficacy of...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1473-2165.2010.00483.x
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Dermal fillers have become an integral part of any aesthetic physician's intervention. AIMS:To assess, by means of ultrasounds, the tissue integration of the hyaluronic acid (HA) dermal filler VYC-25L in chin and jaw. METHODS:Prospective, noncomparative, open-label, and multicenter study conducted on healt...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13632
更新日期：2020-08-04 00:00:00
abstract：BACKGROUND:Synthetic hair fiber implantation first achieved widespread use in the 1970s, but in 1983, the US Federal Drug Administration banned the fibers due to its complications. Currently available synthetic fibers consist of polyamide material, which has been claimed to be effective and safe. Nevertheless, its use ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13318
更新日期：2020-02-15 00:00:00
abstract：BACKGROUND:Abobotulinum- toxin A is used extensively for the treatment of frown (glabellar) lines. AIMS:The aim of this study was to evaluate the efficacy and complications of a new injection technique and to assess the amount of satisfaction in patients with the frown lines. METHODS:This cross-sectional study was co...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12529
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Undecylenoyl phenylalanine is a novel skin-lightening agent, probably acting as α-melanocyte-stimulating hormone (α-MSH) and beta-adrenergic receptor (β-ADR) antagonist. OBJECTIVES:The objective of this double-blind randomized comparative study was to evaluate the efficacy and safety of a preparation contai...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12089
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Both age-related and congenital volume deficiencies may be addressed through the injection of hyaluronic acid (HA) fillers. Deep injection provides structural support, more superficial fat-tissue injection mediates contouring, and superficial intradermal use of HA filler and/or onabotulinumtoxinA may be used...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13596
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Hair plays a significant role in shaping the appearance of an individual. Loss of hair can lead to serious effects on social esteem of an individual. The most common cause of hair loss is Androgenetic Alopecia (AGA).This hereditary disorder followed a specific pattern causing progressive thinning of hair in ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13398
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Riehl's melanosis is a chronic, refractory disorder, which can adversely affect patient's quality of life. Intense pulse light, neodymium-doped yttrium aluminum garnet laser, hydroquinone, tranexamic acid have been reported to treat this disease, but there have been few reports on the effectiveness of other ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13153
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:The increase in the pigmentation of skin grafts during the healing process is a cosmetic problem. There are a variety of medical and surgical treatment options for skin graft darkening. AIMS:The aim of this study was to investigate the effects of topical hydroquinone, tretinoin, and betamethasone applicatio...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13315
更新日期：2020-02-06 00:00:00
abstract：BACKGROUND:Psoriasis is an inflammatory disease that is mostly immune-derived. It causes proliferation of skin cells, forming plaques. Psoriasis etiology is unknown. It might be multifactorial. AIMS:This work aimed to study Smad7 expression in psoriasis vulgaris patients in comparison with normal skin. PATIENTS/METHO...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13425
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Different laser systems are reported to be effective in treatment of telangiectasia and erythema, but comparative studies on 1064-nm neodymium-yttrium aluminum garnet (Nd-YAG) laser and pulsed dye laser (PDL) in treatment of erythemato-telangiectatic rosacea are lacking. Substance (P) is implicated in rosace...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12048
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:New treatments and techniques were being added over the last few years to treat atrophic scars with variable results and adverse effects. AIM OF THE WORK:The aim of this study was to evaluate and compare the therapeutic efficacy and safety of microneedling, autologous platelet-rich plasma, and combination o...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12356
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Body hair removal is an increasing trend that has an impact on the individual's body image. AIMS:To characterize current body hair removal practices in Germany and the extent to which body hair removal was related to demographic characteristics, body image, and body mass index. PATIENTS/METHODS:A national ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13343
更新日期：2020-11-01 00:00:00
abstract：:Psoriasis is a chronic, immune-mediated disease that has a major negative impact on a patient's quality of life. Although several literature reviews indicate that skin microbiota may play an important role in the development and regulation of the immune and inflammatory response of psoriasis, few clinical studies are ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.13752
更新日期：2020-09-30 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Hypertrophic scarring is seen regularly. Tissue penetration of laser energy into hypertrophic scars using computer defaults from some lasers may be insufficient and penetration not enough. We have developed a treatment with an interrupted laser "drilling" by the Ultrapulse CO2 (Manual Fractiona...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12334
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Anecdotal data suggest that combed natural African hair reaches a length steady state. Easier grooming and anticipated long hair have made relaxers popular. OBJECTIVES:These hypotheses were tested in a cross-sectional survey of 1042 school children using a piloted questionnaire and hair length measurements ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2007.00326.x
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:Management of periorbital hyperpigmentation (POH) is still a therapeutic challenge. Although different therapeutic modalities are available, the outcomes of most of them are unsatisfactory. OBJECTIVES:To investigate and compare the efficacy and safety of two new modalities in the treatment of POH; the plate...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.12478
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Vitiligo is a common pigmentary disorder affecting about 1% of the general population. There are numerous medical and surgical treatments. Microneedling is an evolving treatment technique for an expanding number of dermatologic conditions. It is used also to augment transdermal drug delivery through pores cr...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.12704
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:The demand for personalized skin care is increasing rapidly in recent years. In order to provide suitable products for different customers, an accurate assessment of the skin condition is required. It is necessary to establish a remote and convenient method for quantifying skin condition. MATERIALS AND METH...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13576
更新日期：2021-02-01 00:00:00
abstract：:Many cosmetic companies utilize in vitro gene array studies to display significant stimulation or inhibition of various human skin biomarkers to validate in vivo actions that are reported to enhance dermal health. This follows the central dogma of DNA-to-RNA results in protein expression; however, gene and protein exp...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12362
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Glycolic acid (GA) is an effective way of reversing the signs of age and photodamage. GA enhances desquamation of the stratum corneum and induces biological responses that can help restore skin's integrity. GA can, however, cause irritation, especially when its concentration is high, and its pH is low. Thus,...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13570
更新日期：2021-02-01 00:00:00
