Abstract：
BACKGROUND:Spiny keratoderma shows "music box spine" keratotic papules limited to the palms and soles and these lesions do not cause any trouble besides the cosmetic impairment and the sensation of roughness of hands and soles. AIM:To present cases and review the literature on spiny keratoderma. PATIENTS/METHODS, RESULTS:Three cases of spiny keratoderma are presented. The first case is a 52-year-old man with protein S deficiency presented with multiple spiny keratotic papules on palms and soles for more than 30 years, referring to remove them with a razor blade. The second case is an 84-year-old man who was hospitalized due to a rectal adenocarcinoma diagnosed 2 months before and presented multiples papules on palms and soles that were present for more than 50 years, with worsening after being bedridden. The third case is a 59-year-old woman who had since birth together with relatives the same type of spiny keratotic papules on palms and soles. CONCLUSION:The authors discuss the epidemiologic data and differential diagnosis of spiny keratoderma, as well as the related literature. Associations with systemic disease or malignancy occur in some acquired cases. It is important to distinguish from other palmoplantar keratodermas as some of that can be linked to cutaneous and internal malignancies. To date, no cases of spiny keratoderma in patients with protein S deficiency and only one case of association with rectal carcinoma have been reported.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
de Azevedo TP,Sodré CT,Santangelo CL,Quintella DC,Cuzzi T,Ramos-E-Silva Mdoi
10.1111/jocd.13248subject
Has Abstractpub_date
2020-08-01 00:00:00pages
2006-2010issue
8eissn
1473-2130issn
1473-2165journal_volume
19pub_type
杂志文章abstract：BACKGROUND:Melasma is an acquired disorder of symmetrical hyperpigmentation. Several treatment methods are available for patients with melasma, including topical compounds, broad-spectrum photoprotection, camouflage, chemical peels, and laser and light therapies which represent potentially promising options for patient...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.12751
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:The pathophysiology of cellulite involves changes in the subcutaneous adipose layer and the extracellular matrix (ECM) that supports it together with overlying dermal layer. Cellular mechanisms governing cellulite are not fully understood. However, it is accepted that changes include enhanced lipogenesis, de...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1473-2165.2011.00594.x
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Dermal fillers have become an integral part of any aesthetic physician's intervention. AIMS:To assess, by means of ultrasounds, the tissue integration of the hyaluronic acid (HA) dermal filler VYC-25L in chin and jaw. METHODS:Prospective, noncomparative, open-label, and multicenter study conducted on healt...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13632
更新日期：2020-08-04 00:00:00
abstract：:The carboxylic acids include alpha-hydroxyacids (AHAs), polyhydroxy acids (PHAs), aldobionic acids (ABAs), retinoic acid, vitamin C and azelaic acid. They all have therapeutic actions. AHAs, PHAs and ABAs are organic hydroxyacids, a group of natural and physiological substances which can modulate skin keratinization a...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2130.2004.00059.x
更新日期：2004-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Topical aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola (Centella asiatica) may aid in reducing body fat. Lipoxyderm™ contains these ingredients and was used to test if fat loss of the thigh, in conjunction with a low intensity exercise program and restricted calorie intake, was en...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12801
更新日期：2019-08-01 00:00:00
abstract：:Fern pattern technique refers to a novel technique to inject acids gels in the dermis for optimal correction of dynamic facial lines. Although it has been proposed to show good results in correcting dynamic facial lines, it may result in higher risk of postinflammatory hyperpigmentation (PIH) since this technique requ...
journal_title：Journal of cosmetic dermatology
pub_type： 信件
doi：10.1111/j.1473-2165.2010.00511.x
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:Skin color varies among ethnic groups on accounts of genetic background. Within an ethnic group, skin color may also vary according to geographical environments and sun exposure habits. While many reports address skin color differences between ethnic groups, few have compared skin color within as ethnic grou...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12130
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:The addition of hydrophobically modified polymers (HMPs) to cleansers that contain surfactants can create polymer-surfactant complexes that are less irritating to the skin than commercially available mild cleansers. Our objective was to compare the tolerability and efficacy of a test foaming liquid facial ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12061
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:The use of the injectable products for soft tissue augmentation and treatment of skin aging is an uncomfortable, invasive and related to several complications, and chronic reactions, mainly after long-term application. Efforts to develop new topically active anti-aging products with fewer adverse effects are...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13818
更新日期：2020-11-10 00:00:00
abstract：BACKGROUND:Gender-related price inequalities for over-the-counter dermatologic products such as shampoos and conditioners, razors, deodorants, and lotions remain prevalent in the marketplace. This trend has also been found to apply to topical minoxidil, a common treatment for male and female pattern hair loss. OBJECTI...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12954
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and safety associated with use of a 589-nm solid-state laser for treatment of facial erythema. METHODS:A prospective, IRB-approved study was conducted. Participants who were interested in treatment for facial erythema were recruited. They received four monthly treatments with the 589...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12742
更新日期：2018-10-01 00:00:00
abstract：AIMS:To study sun-protective behaviors among skiers and snowboarders on the South Island of New Zealand and to identify associations with personal characteristics or weather conditions. METHODS:Two hundred twenty-six skiers and snowboarders completed an interviewer-administered questionnaire during September and Octob...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2006.00221.x
更新日期：2006-03-01 00:00:00
abstract：INTRODUCTION:There are no evidence-based data how to predict response to therapy in patients with alopecia areata. AIM:The assessment of the predictive value of trichoscopy for the therapeutic outcome in patients with alopecia areata. METHODS:A total of 65 patients with patchy alopecia areata were included into the s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13064
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Xanthelasma palpebrarum (XP) is the most common type of cutaneous xanthoma and has been treated with intralesional injection of pingyangmycin effectively. However, bleomycin, which has the same effect in antitumor activity as pingyangmycin, has not been applied in the treatment of XP. AIMS:To explore and as...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13258
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Ultraviolet (UV) radiation exposure is related to skin and lip tumors. Therefore, the development of photoprotective lipstick formulations is of utmost importance. AIMS:Considering the biological properties of Shea butter (Butyrospermum parkii), we assessed its potential as an adjuvant in a molded lipstick ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13429
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Androgenic alopecia is common, chronic dermatologic disorder. A variety of lasers and light sources appear to be safe and effective in the treatment of AGA. AIMS:To evaluate the efficacy and safety of 1540-nm fractional erbium glass laser in the treatment of AGA. PATIENTS/METHODS:This was an interventional...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.13122
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Management of periorbital hyperpigmentation (POH) is still a therapeutic challenge. Although different therapeutic modalities are available, the outcomes of most of them are unsatisfactory. OBJECTIVES:To investigate and compare the efficacy and safety of two new modalities in the treatment of POH; the plate...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
doi：10.1111/jocd.12478
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:For treating irregular skin pigmentation, a hallmark of premature skin aging, safe and effective alternatives to hydroquinone and kojic acid are being researched. AIMS:Four skin-brightening actives targeting melanin formation at multiple levels, namely disodium glycerophosphate, L-leucine, phenylethyl resor...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2011.00573.x
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:There remains the need for more effective therapeutic options to treat acne vulgaris. Interest in light-based acne treatments has increased, but few randomized, controlled clinical trials assessing the value of photodynamic therapy (PDT) for acne have been reported. AIMS:We sought to examine the efficacy of...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1473-2165.2010.00483.x
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Dermal fillers have been used safely and effectively to revolumize aging hands. We assess the effectiveness of polymethylmethacrylate (PMMA) to treat the volume loss of photoaged dorsal hands for up to 12 months. METHODS:In a 12-month prospective study, 15 subjects were treated with PMMA filler in the bilat...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13445
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Clinical outcomes of eyebrow restoration with single-follicular-unit hair transplantation largely depend on the surgeon's anatomic knowledge, experience, and technical skills. AIMS:To evaluate the effect of the reconstruction with single follicular unit transplantation on eyebrow loss and provide technical ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13242
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Welders are normally at risk of skin cancer due to continuous contact with natural ultraviolet rays and welding radiation. Protective behaviors against the radiations are the most fundamental measures taken to prevent skin cancer in these individuals. AIMS:This research aimed to evaluate the factors affecti...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13092
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:New treatments and techniques were being added over the last few years to treat atrophic scars with variable results and adverse effects. AIM OF THE WORK:The aim of this study was to evaluate and compare the therapeutic efficacy and safety of microneedling, autologous platelet-rich plasma, and combination o...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12356
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis (AD) is an inflammatory pruritic chronic dermatosis involving the alarmin thymic stromal lymphopoietin (TSLP), which is directly implicated in AD pruritus. AIMS:To evaluate the efficacy of Tambourissa trichophylla leaf extract (TTLE) titrated in polyphenols and 18β-glycyrrhetinic acid (GA)...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13515
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Some moisturizing formulations can help restore and maintain the barrier function of the skin. OBJECTIVES:This study was designed to assess the hydration potential of three lamellar moisturizers relative to a control (nonlamellar) moisturizer. METHODS:Healthy adults aged 18 to 65 years with self-reported s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13361
更新日期：2020-11-01 00:00:00
abstract：:Skin aging (intrinsic aging) and photoaging (extrinsic aging) involve a similar process that leads to the typical creased appearance of the skin, with the progressive loss of its physical and biologic properties. Photoaging is a premature skin aging caused by long-term exposure to the ultraviolet B radiations of the s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2005.00198.x
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Subjects seeking facial rejuvenation want the results to appear natural. Currently, however, there is no consensus definition of, or assessment scale for, "naturalness." AIMS:This open-label pilot study explored evaluation techniques and criteria to assess naturalness of facial movement and expression follo...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12961
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Ultraviolet B (UVB) irradiation is viewed as the main factor of skin aging, associated with acceleration of elastin, collagen degradation and expression of matrix metalloproteinases (MMPs). Apples are one of the most commonly eaten fruits in the world, and isoquercitrin is the main active ingredient in new b...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13903
更新日期：2020-12-23 00:00:00
abstract：BACKGROUND:Energy-based devices are increasingly used for noninvasive body contouring. Our aim was to investigate the clinical efficacy of combined radiofrequency and ultrasound device for reduction in body circumference in various body parts. AIMS:The aim of our study was to investigate the clinical efficacy of combi...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13896
更新日期：2020-12-19 00:00:00
abstract：BACKGROUND:Doctors and healthcare workers (HCW) are at frontline in control of the pandemic caused by the novel coronavirus infection (COVID-19). The virus is transmitted by contact, droplet, and airborne transmission; hence, hand hygiene, social distancing, environmental disinfection, and use of appropriate personal p...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.13736
更新日期：2020-12-01 00:00:00
