Abstract：
INTRODUCTION:There are no evidence-based data how to predict response to therapy in patients with alopecia areata. AIM:The assessment of the predictive value of trichoscopy for the therapeutic outcome in patients with alopecia areata. METHODS:A total of 65 patients with patchy alopecia areata were included into the study. Trichoscopy was performed at baseline and 2 months after the treatment initiation. After 6 months, patients were classified as responders (27/65) and nonresponders (38/65). RESULTS:There were no differences between the groups in baseline trichoscopy. After 2 months, black dots, broken hairs, exclamation mark hairs, and tapered hairs occurred significantly more often in nonresponders compared to responders (19/38, 50% vs 3/27, 11%; 26/38, 68% vs 6/27, 22%; 23/38, 61% vs 5/27, 19% and 11/38, 29% vs 0/27, 0%, respectively). Upright regrowing hairs and pigtail hairs occurred significantly more often in responders compared to nonresponders (27/27, 100% vs 21/38, 55% and 9/27, 33% vs 3/38, 8%, respectively). A trichoscopy-based Alopecia Areata Predictive Score (min -4 to max 2) was developed. Probability of hair regrowth was 98.3%, 88.7%, 52.3%, 13.2%, 2.1%, 0.3%, and 0% in patients with score 2, 1, 0, -1, -2, -3, and -4, respectively. CONCLUSIONS:In patchy alopecia areata, upright regrowing hairs and pigtail hairs are positive, while black dots, broken hairs, exclamation mark hairs, and tapered hairs negative predictive markers. Alopecia Areata Predictive Score is new trichoscopy-based tool to predict treatment outcome in patients with patchy alopecia areata.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Waśkiel-Burnat A,Rakowska A,Sikora M,Olszewska M,Rudnicka Ldoi
10.1111/jocd.13064subject
Has Abstractpub_date
2020-03-01 00:00:00pages
746-751issue
3eissn
1473-2130issn
1473-2165journal_volume
19pub_type
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abstract：:Cutaneous hypermelanoses are frequently encountered conditions that can have severe adverse psychosocial and emotional effects on affected patients. Melasma, postinflammatory hyperpigmentation, drug-induced pigmentation, and erythema dischromicum perstans are among the most common cutaneous disorders leading to acquir...
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abstract：:Leg telangiectasia is more difficult to treat than facial telangiectasia. Investigations may be needed to elucidate the origin of the telangiectasia. In cases of venous insufficiency, investigation of venous haemodynamics is desirable. Treatment is primarily by sclerotherapy, including foam sclerotherapy. Light and la...
journal_title：Journal of cosmetic dermatology
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abstract：:We described-along with a genetic predisposition and exposure to sunlight, as the main factors for melasma development-pregnancy, hormonal therapies, and oral contraceptive pills. Whilst hormonal alteration or therapies are frequently reported in literature in association with melasma, studies analyzing the laboratori...
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journal_title：Journal of cosmetic dermatology
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doi：10.1111/j.1473-2165.2006.00232.x
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abstract：BACKGROUND:Human hair cuticle is always exposed to various stresses and then gradually lost in daily life. There are two typical patterns of cuticle damage: type L, where the cell membrane complex, the structure located between cuticle cells, is split and the cuticle lifts up, and type E, where the fragile substructure...
journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
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abstract：BACKGROUND:Scrubbing of the skin during Hammam, a Turkish spa treatment, removes cells from the ultraviolet radiation absorbing stratum corneum. AIM:The aim of this study was to assess if skin is more susceptible to sunburn after a Hammam treatment. METHODS:In this randomized controlled trial with a paired design, he...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12829
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abstract：BACKGROUND:Application of radiofrequency (RF) energy with microneedles to facial skin shown to promote skin renewal. AIM:To evaluate the safety and efficacy of the VoluDerm technology with 100 ultra-thin electrodes gen100 tip for improvement of skin texture and wrinkles. METHODS:A prospective, open-label, intra-indiv...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13239
更新日期：2020-02-01 00:00:00
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2008.00369.x
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Cutaneous hyperchromias are disorders of skin pigmentation involving an increase of melanin production and its irregular accumulation in skin cells. It is known that the use of sunscreens helps to prevent changes in the skin pigmentation pattern, but the structural and morphological alterations that occur in...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12307
更新日期：2017-09-01 00:00:00
abstract：:In contrast to the female breast the male breast has gained much less attention by aesthetic surgery and cosmetic dermatology. In this review a focus on minimally invasive procedures to correct aesthetic problems of male breast are discussed. The major indications are gynecomastia, breast asymmetry, and body sculpturi...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2011.00548.x
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND:The intracellular form of action of retinoids requires these agents to reach deeper layers of the skin with viable cells to ensure therapeutic efficiency. However, studies on swine skin models show that some retinoids have low skin permeability. Thus, the association of innovative formulations with technolog...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13826
更新日期：2020-11-03 00:00:00
abstract：INTRODUCTION:The addition of hydrophobically modified polymers (HMPs) to cleansers that contain surfactants can create polymer-surfactant complexes that are less irritating to the skin than commercially available mild cleansers. Our objective was to compare the tolerability and efficacy of a test foaming liquid facial ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12061
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Androgenic alopecia is common, chronic dermatologic disorder. A variety of lasers and light sources appear to be safe and effective in the treatment of AGA. AIMS:To evaluate the efficacy and safety of 1540-nm fractional erbium glass laser in the treatment of AGA. PATIENTS/METHODS:This was an interventional...
journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
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abstract：OBJECTIVES:Para rubber (Hevea brasiliensis (Willd. ex A. Juss.) Müll. Arg.)) is the important crop of the word. It has been vastly used in biomedical products. However, its pharmacologically application besides the latex is sparely to be explored especially the seed. Cellular biological activities of the standardized p...
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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更新日期：2003-07-01 00:00:00
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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更新日期：2016-09-01 00:00:00
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
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更新日期：2012-06-01 00:00:00
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
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更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Facial telangiectasia is one of the common skin vascular lesions characterized by dilated cutaneous vasculatures. The variety of diameters and difference in depths of lesional blood vessels are the major challenges for effective treatments for Facial telangiectasia. AIMS:To compare the efficacy and safety p...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Skin care influences skin barrier function during the first postnatal weeks. Although the use of natural oils in preterms has been investigated, there are currently no data comparing the effect of sunflower oil to an emollient on barrier development in healthy term newborns. METHODS:In a prospective, random...
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pub_type： 杂志文章,随机对照试验
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更新日期：2017-12-01 00:00:00
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journal_title：Journal of cosmetic dermatology
pub_type： 临床试验,杂志文章
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更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Many methods have been performed to achieve a satisfying outcome in acne scars but some of them were high cost and also were associated with low results and some complications. OBJECTIVES:To evaluate and compare the efficacy and safety therapy of glycolic acid (GA) peel, microneedling with dermapen and a co...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:As the face is known for its extreme variation in vascular anatomy and the number of filler-associated complications due to intra-arterial injection is increasing, we are in need of a method to visualize anyone's individual arterial anatomy of the face in a completely harmless way. AIMS:The different medica...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
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更新日期：2021-02-01 00:00:00
