Abstract:
BACKGROUND:Subjects seeking facial rejuvenation want the results to appear natural. Currently, however, there is no consensus definition of, or assessment scale for, "naturalness." AIMS:This open-label pilot study explored evaluation techniques and criteria to assess naturalness of facial movement and expression following optimal bilateral correction of moderate-to-severe nasolabial folds and marionette lines with soft-tissue hyaluronic acid fillers formulated with XpresHAn Technology™. METHODS:Primary efficacy was investigator assessed naturalness of dynamic expressions using baseline and Day 42 posttreatment 2D video. Other evaluations included investigator assessed naturalness using static images, wrinkle severity, investigator and subject Global Aesthetic Improvement Scale assessments, and subject satisfaction. RESULTS:Thirty Caucasian females (41-65 years) received either Restylane® Refyne, Restylane® Defyne or both. Naturalness of dynamic expressions was at least maintained in all subjects. Naturalness of static expressions was not negatively affected in most subjects (96.7%). For dynamic expressions, 83.3% of subjects showed enhanced attractiveness, younger appearance and maintained naturalness. CONCLUSIONS:Overall, nasolabial folds and marionette lines improved significantly based on severity and Global Aesthetic Improvement Scale scores, with high subject satisfaction and favorable safety profile. Based on subject satisfaction and investigator assessments, using highly flexible hyaluronic acid dermal fillers did not compromise naturalness of lower facial expressions while achieving the desired improvements in attractiveness and youthfulness. The preliminary results obtained in this pilot study suggest that dynamic and static assessments of facial animation may aid the evaluation of natural outcomes in facial rejuvenation procedures.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Solish N,Bertucci V,Percec I,Wagner T,Nogueira A,Mashburn Jdoi
10.1111/jocd.12961subject
Has Abstractpub_date
2019-06-01 00:00:00pages
738-746issue
3eissn
1473-2130issn
1473-2165journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Pediatric hypertrophic burn scars are challenging to treat due to their widespread nature and pain associated with the treatment. Intralesional triamcinolone acetonide (TAC) injection with or without 5-fluorouracil (5FU) is considered first-line treatment for severe hypertrophic scars. The pain associated wi...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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abstract:OBJECTIVES:To measure the effects of platelet-rich plasma (PRP) on hair diameter in Pakistani population. MATERIALS AND METHODS:The study was conducted in a private setup in the adult patients undergoing PRP treatment. Baseline platelets count was noted for each patient. PRP was prepared using a commercial kit. Three ...
journal_title:Journal of cosmetic dermatology
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
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更新日期:2020-11-29 00:00:00
abstract:BACKGROUND:Facial lipoatrophies are rare disfiguring syndromes, most commonly characterized by loss of buccal fat pads. AIMS:To demonstrate a relationship between facial lipoatrophy and a new synthetic filler device (Profill) used to correct naso-labial folds. METHODS:Five cases of lipoatrophy, appeared 9 months or l...
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2008.00369.x
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of injection of autologous keratin gel and fibroblast for neck aging as soft tissue filler. MATERIALS AND METHODS:Totally 30 volunteers received treatment of autologous keratin and fibroblast for neck wrinkles and 5 of them received hyaluronic acid (HA) treatment as control. Clini...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2018-08-01 00:00:00
abstract::The authors report the case of a 58-year-old woman presenting with "puffiness" in her lower eyelids persisting for approximately 5 years. While dark, puffy eyelid circles following hyaluronic acid placement periorbitally are not uncommon, what is so unusual in our case is that it was noted 5 years after treatment with...
journal_title:Journal of cosmetic dermatology
pub_type: 信件
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更新日期:2012-09-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2017-09-01 00:00:00
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更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Management of periorbital hyperpigmentation (POH) is still a therapeutic challenge. Although different therapeutic modalities are available, the outcomes of most of them are unsatisfactory. OBJECTIVES:To investigate and compare the efficacy and safety of two new modalities in the treatment of POH; the plate...
journal_title:Journal of cosmetic dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/jocd.12478
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Topical aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola (Centella asiatica) may aid in reducing body fat. Lipoxyderm™ contains these ingredients and was used to test if fat loss of the thigh, in conjunction with a low intensity exercise program and restricted calorie intake, was en...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jocd.12801
更新日期:2019-08-01 00:00:00
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更新日期:2020-09-01 00:00:00
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更新日期:2020-07-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2007-12-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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