Combination therapy with salicylic acid chemical peels, glycyrrhizin compound, and vitamin C for Riehl's melanosis.

Abstract:

BACKGROUND:Riehl's melanosis is a chronic, refractory disorder, which can adversely affect patient's quality of life. Intense pulse light, neodymium-doped yttrium aluminum garnet laser, hydroquinone, tranexamic acid have been reported to treat this disease, but there have been few reports on the effectiveness of other treatments. AIM:To assess the efficacy and safety of triple combination therapy with salicylic acid chemical peels, oral glycyrrhizin compound, and vitamin C for Riehl's melanosis. PATIENTS/METHODS:Three patients diagnosed with Riehl's melanosis were enrolled. All patients were treated with glycyrrhizin compound (150 mg/d), vitamin C (100 mg/d), and salicylic acid 30% peels once every 2 weeks. Clinical photographs and VISIA were used to assess the efficacy. RESULTS:All patients received obvious improvement and reported no obvious side effects. CONCLUSION:Triple combination therapy with salicylic acid peels, oral glycyrrhizin compound, and vitamin C is a safe and effective modality for Riehl's melanosis.

journal_name

J Cosmet Dermatol

authors

Wang L,Wen X,Hao D,Li Y,Du D,Jiang X

doi

10.1111/jocd.13153

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

1377-1380

issue

6

eissn

1473-2130

issn

1473-2165

journal_volume

19

pub_type

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