Abstract：
BACKGROUND:Acne vulgaris is an inflammatory disorder with a profound heterogenous aetio-pathophysiology. ACE gene I/D polymorphism affects angiotensin-converting enzyme activities that play a role in inflammation. However, there are no molecular genetic studies investigating the contribution of ACE gene insertion/deletion polymorphism in the genetic background of acne vulgaris. AIMS:The aim of this work was to reveal the relation between the ACE gene I/D polymorphism and acne vulgaris development among a sample of patients. PATIENTS AND METHODS:This study included 100 acne vulgaris patients in addition to 120 matched control subjects. The ACE gene I/D polymorphism was analyzed using polymerase chain reaction (PCR). RESULTS:The distribution of DD, ID genotypes, and D allele showed higher frequency in AV patients than in controls (P < 0.001 for all). Moreover, positive family history and ACEI/D gene polymorphism (DD + ID genotypes) were considered as independent predictors for severe acne grades (P ≤ 0.001 and 0.046, respectively) in multivariate analysis. CONCLUSIONS:The current study results suggest that the D allele of the ACE I/D gene polymorphism might confer risk to AV among the studied patients. Moreover, ACE I/D gene polymorphism and positive family history were considered as independent predictors of severe AV.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Sorour NE,Mustafa AI,Alhusseni NF,Fawzy E,Amer AGdoi
10.1111/jocd.12937subject
Has Abstractpub_date
2019-12-01 00:00:00pages
1992-1997issue
6eissn
1473-2130issn
1473-2165journal_volume
18pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:Topical aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola (Centella asiatica) may aid in reducing body fat. Lipoxyderm™ contains these ingredients and was used to test if fat loss of the thigh, in conjunction with a low intensity exercise program and restricted calorie intake, was en...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12801
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Lichen Planus Pigmentosus (LPP), a disorder with stubborn treatment-refractory hyperpigmentation predominantly affects the darker skin. Deep dermal pigmentary incontinence of LPP renders the condition treatment-refractory. OBJECTIVES:Lack of a consistently effective depigmenting treatment protocol of inacti...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12862
更新日期：2019-01-20 00:00:00
abstract：BACKGROUND:Ultraviolet (UV) radiation has been implicated in photoaging and various types of skin carcinomas. Although the human skin has evolved several defense mechanisms to survive the insults of actinic damage like keratinization, melanin pigmentation, etc., it is still subjected to the harmful effects of sunlight....
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2007.00293.x
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:Recent studies have reported that the incidence of acne combined with rosacea is increasing. However, the clinical feature and inducing factor of these two diseases co-occurrence is remain unclear. AIMS:This study aims to investigate the classification and severity of female patients combining with acne and...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13762
更新日期：2020-10-06 00:00:00
abstract：BACKGROUND:Glycolic acid (GA) is an effective way of reversing the signs of age and photodamage. GA enhances desquamation of the stratum corneum and induces biological responses that can help restore skin's integrity. GA can, however, cause irritation, especially when its concentration is high, and its pH is low. Thus,...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13570
更新日期：2021-02-01 00:00:00
abstract：:Skin resurfacing has been a part of cosmetic dermatology for more than two decades now, and most of it has been ablative with traditional aggressive lasers including the CO(2) and erbium. The last few years have seen a revolutionary change with the invention of nonablative lasers for skin tightening. Fractional resurf...
journal_title：Journal of cosmetic dermatology
pub_type： 历史文章,杂志文章,评审
doi：10.1111/j.1473-2165.2010.00528.x
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis (AD) is an inflammatory pruritic chronic dermatosis involving the alarmin thymic stromal lymphopoietin (TSLP), which is directly implicated in AD pruritus. AIMS:To evaluate the efficacy of Tambourissa trichophylla leaf extract (TTLE) titrated in polyphenols and 18β-glycyrrhetinic acid (GA)...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13515
更新日期：2020-08-01 00:00:00
abstract：:The American Academy of Dermatology (AAD) has prioritized skin cancer prevention efforts in 2018, as photoprotection measures adopted by the general public remain suboptimal. A large proportion of patients lack understanding of primary prevention methods for skin cancer, and mistruths in advertising may contribute sig...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12743
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:The increase in the pigmentation of skin grafts during the healing process is a cosmetic problem. There are a variety of medical and surgical treatment options for skin graft darkening. AIMS:The aim of this study was to investigate the effects of topical hydroquinone, tretinoin, and betamethasone applicatio...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13315
更新日期：2020-02-06 00:00:00
abstract：INTRODUCTION:There are no evidence-based data how to predict response to therapy in patients with alopecia areata. AIM:The assessment of the predictive value of trichoscopy for the therapeutic outcome in patients with alopecia areata. METHODS:A total of 65 patients with patchy alopecia areata were included into the s...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13064
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Lip enhancement using fillers improves appearance by increasing fullness, enhancing lip definition, and reducing fine lines and wrinkles around the lips. AIMS:To investigate a 24 mg/mL hyaluronic acid (HA) with pre-incorporated lidocaine gel for lip definition and enhancement, medium-deep lines, and oral co...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2010.00539.x
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:At present, it is no longer possible to use animal testing for ingredients and cosmetic products in the Organisation for Economic Co-operation and Development (OECD) member states. However, in vitro tests are widely used to determine the safety and efficacy of ingredients and medicines. OBJECTIVE:Obviously,...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13789
更新日期：2020-10-14 00:00:00
abstract：BACKGROUND:The application of ingredients from marine and maritime origins is increasingly common in skin care products, driven by consumer expectations for natural ingredients. However, these ingredients are typically studied for a few isolated in vitro activities. OBJECTIVES:The purpose of this study was to carry ou...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12528
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:A variety of energy-based devices have been used to treat acne. However, all studies have been subjective and have not involved double-blind and randomized controlled studies. AIMS:We undertook a randomized controlled study evaluating the use of a 650 usec 1064 nm Nd:YAG laser compared with a sham in the tr...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13480
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Synthetic hair fiber implantation first achieved widespread use in the 1970s, but in 1983, the US Federal Drug Administration banned the fibers due to its complications. Currently available synthetic fibers consist of polyamide material, which has been claimed to be effective and safe. Nevertheless, its use ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13318
更新日期：2020-02-15 00:00:00
abstract：OBJECTIVES:To measure the effects of platelet-rich plasma (PRP) on hair diameter in Pakistani population. MATERIALS AND METHODS:The study was conducted in a private setup in the adult patients undergoing PRP treatment. Baseline platelets count was noted for each patient. PRP was prepared using a commercial kit. Three ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12510
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Human hair cuticle is always exposed to various stresses and then gradually lost in daily life. There are two typical patterns of cuticle damage: type L, where the cell membrane complex, the structure located between cuticle cells, is split and the cuticle lifts up, and type E, where the fragile substructure...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12129
更新日期：2015-03-01 00:00:00
abstract：:Nutracosmetics are an emerging class of health and beauty aid products that combine the benefits of nutracosmetical ingredients with the elegance, skin feel, and delivery systems of cosmetics. Herbs and spices have been used in maintaining and enhancing human beauty because herbs have many beneficial properties, such ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2008.00369.x
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Palmar hyperhidrosis (PH) can produce social and occupational difficulties and reduce the quality of life of those who suffer from this kind of problem. When dealing with focal hyperhidrosis, the patients' attitudes and their subjective approaches regarding the process may influence the objective evaluation ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2005.00304.x
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND:Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin aging. Nutrition is a key factor influencing skin health and consequently its appearance. A wide range of dietary supplements is offered to improve skin health. Collagen peptides are used as a bioactive ...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jocd.12174
更新日期：2015-12-01 00:00:00
abstract：:Facial expressions convey emotions that form the foundation of interpersonal relationships, and many of these emotions promote and regulate our social linkages. Hence, the facial aging symptomatological analysis and the treatment plan must of necessity include knowledge of the facial dynamics and the emotional express...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12128
更新日期：2015-03-01 00:00:00
abstract：AIMS:Bromhidrosis is a common problem with a severe negative impact on the patient's social and emotional life. The objective of this open-label study was to evaluate the efficacy and safety of a local product with the main active ingredient of glycine-soja sterocomplex in the treatment of local bromhidrosis. PATIENTS...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/j.1473-2165.2010.00536.x
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:The demand for personalized skin care is increasing rapidly in recent years. In order to provide suitable products for different customers, an accurate assessment of the skin condition is required. It is necessary to establish a remote and convenient method for quantifying skin condition. MATERIALS AND METH...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.13576
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Bimatoprost has known adnexal activity and was observed to increase nail growth at two clinical centers. OBJECTIVES:In this randomized, double-blinded, placebo-controlled pilot study, we examine the effect of bimatoprost (Lumigan 0.01%), applied bid to the proximal nail fold on nail growth, nail brittleness...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/jocd.12372
更新日期：2018-04-01 00:00:00
abstract：:Twin studies, especially those involving monozygotic (MZ) twins, facilitate the analysis of factors affecting skin aging while controlling for age, gender, and genetic susceptibility. The purpose of this study was to objectively assess various features of facial skin and analyze the effects of environmental factors on...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12081
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Microdermabrasion is a nonchemical superficial resurfacing procedure that removes the stratum corneum. Because it is a somewhat subtle procedure, it may be difficult to demonstrate its cosmetic benefit. OBJECTIVES:To assess the efficacy of microdermabrasion in treatment of melasma, postacne scarring, striae...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12252
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Androgenetic alopecia (AGA) is the most common cause of alopecia in men. In the literature, although there are in vitro studies investigating the relationship between oxidative stress and AGA, any in vivo study does not exist. AIM:Our aim was to evaluate the oxidative stress status in male patients with ear...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
doi：10.1111/jocd.12300
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Doctors and healthcare workers (HCW) are at frontline in control of the pandemic caused by the novel coronavirus infection (COVID-19). The virus is transmitted by contact, droplet, and airborne transmission; hence, hand hygiene, social distancing, environmental disinfection, and use of appropriate personal p...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.13736
更新日期：2020-12-01 00:00:00
abstract：:To review indexed literature concerning adverse ocular effects of the most common aesthetic facial procedures (light-emitting therapy, dermal fillers injection, and botulinum toxin). Literature search using three online databases - PubMed, SciELO, and Capes - selecting case reports, series of cases and reviews, with n...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/jocd.12141
更新日期：2015-06-01 00:00:00
abstract：:Cutaneous hypermelanoses are frequently encountered conditions that can have severe adverse psychosocial and emotional effects on affected patients. Melasma, postinflammatory hyperpigmentation, drug-induced pigmentation, and erythema dischromicum perstans are among the most common cutaneous disorders leading to acquir...
journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
doi：10.1111/j.1473-2165.2006.00276.x
更新日期：2006-12-01 00:00:00
