Abstract:
BACKGROUND:Lichen Planus Pigmentosus (LPP), a disorder with stubborn treatment-refractory hyperpigmentation predominantly affects the darker skin. Deep dermal pigmentary incontinence of LPP renders the condition treatment-refractory. OBJECTIVES:Lack of a consistently effective depigmenting treatment protocol of inactive LPP mandates exploration of novel approaches. We analyzed the effect of six sessions of modified phenol peel on reduction of pigmentation of LPP in Indian patients. METHODS:The results of a retrospective analysis of the efficacy and safety of six sessions of Croton oil free phenol combination (CFPC) peel done every 3 weeks, for inactive LPP-associated hyperpigmentation in 17 patients are presented. Efficacy evaluation was done with patient-reported improvement, physician-evaluated improvement (photographic comparison of baseline and post-treatment clinical images), and pre- and posttreatment comparison of dermoscopic images using a simple scale. RESULTS:Out of 17, 5 (29%) patients sustained excellent improvement with >75% reduction of pigmentation. Overall 13 (76%) patients had moderate to excellent improvement, that is, at least 25% or more reduction in pigmentation. The patient-reported improvement, physician-graded improvement, and dermoscopic changes-all three measures showed harmonious overlap. Lightening of the background color and reduction in density and color intensity of pigmented structures was observed on dermoscopy in majority of patients. The treatment was well tolerated with no serious local/systemic adverse effects. CONCLUSIONS:Modified phenol peels seem effective in reduction of hyperpigmentation of LPP. They are safe and well tolerated. Thorough priming, stringent sun protection and use of post-peel adjuvant topicals boost the peel effect and aid in maintaining the effect for up to a year.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Sonthalia S,Vedamurthy M,Thomas M,Goldust M,Jha AK,Srivastava S,Aggarwal Idoi
10.1111/jocd.12862subject
Has Abstractpub_date
2019-01-20 00:00:00eissn
1473-2130issn
1473-2165pub_type
杂志文章abstract:BACKGROUND:There remains the need for more effective therapeutic options to treat acne vulgaris. Interest in light-based acne treatments has increased, but few randomized, controlled clinical trials assessing the value of photodynamic therapy (PDT) for acne have been reported. AIMS:We sought to examine the efficacy of...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1473-2165.2010.00483.x
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Clinical outcomes of eyebrow restoration with single-follicular-unit hair transplantation largely depend on the surgeon's anatomic knowledge, experience, and technical skills. AIMS:To evaluate the effect of the reconstruction with single follicular unit transplantation on eyebrow loss and provide technical ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13242
更新日期:2020-08-01 00:00:00
abstract::Many cosmetic companies utilize in vitro gene array studies to display significant stimulation or inhibition of various human skin biomarkers to validate in vivo actions that are reported to enhance dermal health. This follows the central dogma of DNA-to-RNA results in protein expression; however, gene and protein exp...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-09-06 00:00:00
abstract:BACKGROUND:Abobotulinum- toxin A is used extensively for the treatment of frown (glabellar) lines. AIMS:The aim of this study was to evaluate the efficacy and complications of a new injection technique and to assess the amount of satisfaction in patients with the frown lines. METHODS:This cross-sectional study was co...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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journal_title:Journal of cosmetic dermatology
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更新日期:2018-06-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2019-12-01 00:00:00
abstract::To review indexed literature concerning adverse ocular effects of the most common aesthetic facial procedures (light-emitting therapy, dermal fillers injection, and botulinum toxin). Literature search using three online databases - PubMed, SciELO, and Capes - selecting case reports, series of cases and reviews, with n...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
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更新日期:2015-06-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 信件
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更新日期:2008-09-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Facial lipoatrophies are rare disfiguring syndromes, most commonly characterized by loss of buccal fat pads. AIMS:To demonstrate a relationship between facial lipoatrophy and a new synthetic filler device (Profill) used to correct naso-labial folds. METHODS:Five cases of lipoatrophy, appeared 9 months or l...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2002-10-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1473-2165.2008.00379.x
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Infraorbital dark circles (DC) are defined as a symptom that presents darkness under infraorbital eyelids. The objective of this study was to evaluate the efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol (PR) for the treatment of infraorbital dark circles. METHODS:Twenty female partic...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-08-11 00:00:00
abstract:BACKGROUND:Type XVI collagen is a member of the fibril-associated collagens with interrupted triple helices; however, its function or regulation remain unclear. AIMS:This study is to examine the effect of ultraviolet B (UVB) or photoaging on type XVI collagen expression in various cultured cells, mouse, and human skin...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2165.2012.00612.x
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2021-02-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-08-11 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-11-10 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2018-12-01 00:00:00
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journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
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更新日期:2020-02-06 00:00:00
abstract::Moisturizers are used on large body surfaces to maintain the smoothness of the skin and to break the dry-skin cycle. Many healthcare professionals and patients overlook the importance of moisturizers and do not consider them to be 'active' treatments. However, evidence from clinical and experimental studies shows that...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/j.1473-2130.2004.00062.x
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Ultraviolet (UV) radiation exposure is related to skin and lip tumors. Therefore, the development of photoprotective lipstick formulations is of utmost importance. AIMS:Considering the biological properties of Shea butter (Butyrospermum parkii), we assessed its potential as an adjuvant in a molded lipstick ...
journal_title:Journal of cosmetic dermatology
pub_type: 杂志文章
doi:10.1111/jocd.13429
更新日期:2020-12-01 00:00:00