Abstract：
BACKGROUND:Acne vulgaris is a common cosmetic problem that is frequently associated with psychosocial disturbances as well as increased oxidative stress. However, oxidative stress and psychological aspects have been studied separately in acne. OBJECTIVE:To evaluate the relationships between oxidative stress, anxiety, depression, and quality of life in acne patients. METHODS:Sixty patients with facial acne and 40 age- and sex-matched healthy individuals were included in the study. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS), and quality of life (QoL) was measured by the Cardiff Acne Disability Index. Disease severity was assessed using the Combined Acne Severity Classification. The serum levels of zinc and malondialdehyde (MDA) and total antioxidant capacity (TAC) were measured in patients and healthy subjects. RESULTS:The mean HADS scores for anxiety and depression were higher in patients than controls (P<.001 for both). Acne patients showed higher serum MDA and lower TAC and serum zinc levels compared with control subjects (P=.019, P<.001, and P=.028, respectively). Anxiety and depression scores did not correlate with oxidative stress parameters. Patients with moderate/severe acne had worse anxiety scores than mild acne (P=.048), and higher anxiety scores were associated with poorer quality of life (r=.436, P=.001). CONCLUSION:Our results indicate that the high levels of anxiety and depression in patients with facial acne were not related to oxidative stress. Anxiety was more common than depression and was directly related to QoL impairment.
journal_name
J Cosmet Dermatoljournal_title
Journal of cosmetic dermatologyauthors
Awad SM,Morsy H,Sayed AA,Mohamed NA,Ezzat GM,Noaman MMdoi
10.1111/jocd.12366subject
Has Abstractpub_date
2018-04-01 00:00:00pages
203-208issue
2eissn
1473-2130issn
1473-2165journal_volume
17pub_type
杂志文章abstract：BACKGROUND:Petrolatum is often used to suppress water evaporation from the skin surface. However, its stickiness, shininess, and other factors make it inconvenient for continuous use. OBJECTIVE:To compare the effectiveness and usability between a newly developed petrolatum-based ointment (NOV® II Moisture Balm) and wh...
journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
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journal_title：Journal of cosmetic dermatology
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pub_type： 杂志文章,评审
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章,评审
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pub_type： 信件
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pub_type： 杂志文章
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更新日期：2020-04-01 00:00:00
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更新日期：2016-06-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：2018-12-16 00:00:00
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pub_type： 杂志文章,随机对照试验
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journal_title：Journal of cosmetic dermatology
pub_type： 杂志文章
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更新日期：2020-05-01 00:00:00
